Houston rises in the ranks of best cities for veteran entrepreneurs

best of the rest

Houston is among the top cities for veteran entrepreneurs. Photo via Getty Images

Houston has moved up the ranks in an annual study of the top places in the U.S. for veteran entrepreneurs.

The study, conducted by the PenFed Foundation and Edelman Data & Intelligence, puts Houston at No. 5 among the best metro areas for veteran entrepreneurs. That’s up from No. 12 in the 2021 study.

The study cites Houston’s economic growth, support for veterans, strong employment, and low unemployment rate among veterans as factors favoring veteran entrepreneurs.

More than 300,000 military veterans live in the Houston area. That’s the second largest population of veterans in the U.S.

Due to the Houston area’s robust veteran population, Bayou City was chosen in 2018 as the site for the third local chapter of Bunker Labs, an accelerator and incubator for military-affiliated entrepreneurs.

At No. 1 in the study is Washington, D.C., followed by:

2. New York City
3. Seattle
4. Dallas-Fort Worth
5. Houston
6. Austin
7. Sioux Falls, South Dakota
8. Cleveland
9. Rapid City, South Dakota
10. Boston

Elsewhere in Texas, McAllen-Edinburg-Mission landed at No. 20 and San Antonio at No. 23.

The study analyzed four categories for each city: livability, economic growth, support for veterans, and ability to start a business. The study evaluated 390 metro areas.

“As the nation navigates the economic impacts of inflation, the study focused especially on how inflation impacts cities differently,” says the PenFed Foundation, established by PenFed Credit Union.

This is the third year for the study.

“We want to help cities across the United States understand which environments are best suited for military veterans to start and grow businesses, and inspire city leaders to take the actions needed to support veteran entrepreneurs,” James Schenck, president and CEO of PenFed Credit Union and CEO of the foundation, says in a news release.

Three Houston companies will pitch in Rice University's competition for veteran-owned startups. Courtesy of Rice University

3 Houston startups to compete in Rice University's Veterans Business Battle

It's on.

Rice University will soon play host to its 2019 Veterans Business Battle, where 20 veteran-owned companies — three of which are from Houston — will pitch their business models and compete for prize money and investment offers.

On April 12, the 20 semifinalists will pitch to a panel of investors, who will choose the top five. Those finalists will pitch the next ay, April 13, in hopes of taking home some of the awards.

"We are very excited about the great group of companies that are coming to Houston next month," says event co-chairman Asad Akram in a release. "It's our goal to introduce them to a network that can help their businesses grow and succeed."

The Houston-based companies competing are Amor Oral, Welcome Connect and FeedMe Fitness, according to a release from Rice University. Amor Oral specializes in the manufacturing and sale of edible, organic personal lubricants. The company's lubricants are all water-based, and Amor Oral claims to offer the largest selection of flavored personal lubricants in the U.S.

FeedMe Fitness, another Houston competitor, is a subscription service that offers customized workouts and meal plans to its subscribers. Welcome Connect is a real estate platform that connects real estate agents with prospective buyers.

More than $3 million has been invested in veteran-owned businesses since the competition's launch in 2015. All the competitors are ultimately after the same thing: investments that will help them launch or expand. The competitor pool includes newly launched ventures and owner-operated businesses, per the Rice release, and all semifinalists can potentially receive investment offers.

A handful of competitors are from Texas. Those competitors include the Dallas-based companies And I Like It and City Gym, Floresville-based Harvard Telemedicine, Fort Worth-based Harvest Returns, Wimberly-based Power Polymer, Corpus Christ-based Rock N Roe Aquaponics, and Bryan-based Zanbazan.

The remaining competitors from around the U.S. are:

 
  • Gotta Have It Fan Foams, from Springfield, Virginia
    •  
  • Family Proud, from San Diego
    •  
  • High Country Air Service, from Albuquerque, New Mexico
    •  
  • Knifehand Nutrition, from Syracuse, New York
    •  
  • Maco, from New York
    •  
  • Off Duty Blue, from Syracuse, New York
    •  
  • Randian, from Los Angeles
    •  
  • Reimbi, from Portland, Oregon
    •  
  • Safe Stamp, from Nashville
    •  
  • SEE ID, from Newcastle, Washington
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Rice team keeps CO2-to-fuel devices running 50 times longer in new study

Bubbling Up

In a new study published in the journal Science, a team of Rice University researchers shared findings on how acid bubbles can improve the stability of electrochemical devices that convert carbon dioxide into useful fuels and chemicals.

The team led by Rice associate professor Hoatian Wang addressed an issue in the performance and stability of CO2 reduction systems. The gas flow channels in the systems often clog due to salt buildup, reducing efficiency and causing the devices to fail prematurely after about 80 hours of operation.

“Salt precipitation blocks CO2 transport and floods the gas diffusion electrode, which leads to performance failure,” Wang said in a news release. “This typically happens within a few hundred hours, which is far from commercial viability.”

By using an acid-humidified CO2 technique, the team was able to extend the operational life of a CO2 reduction system more than 50-fold, demonstrating more than 4,500 hours of stable operation in a scaled-up reactor.

The Rice team made a simple swap with a significant impact. Instead of using water to humidify the CO2 gas input into the reactor, the team bubbled the gas through an acid solution such as hydrochloric, formic or acetic acid. This process made more soluble salt formations that did not crystallize or block the channels.

The process has major implications for an emerging green technology known as electrochemical CO2 reduction, or CO2RR, that transforms climate-warming CO2 into products like carbon monoxide, ethylene, or alcohols. The products can be further refined into fuels or feedstocks.

“Using the traditional method of water-humidified CO2 could lead to salt formation in the cathode gas flow channels,” Shaoyun Hao, postdoctoral research associate in chemical and biomolecular engineering at Rice and co-first author, explained in the news release. “We hypothesized — and confirmed — that acid vapor could dissolve the salt and convert the low solubility KHCO3 into salt with higher solubility, thus shifting the solubility balance just enough to avoid clogging without affecting catalyst performance.”

The Rice team believes the work can lead to more scalable CO2 electrolyzers, which is vital if the technology is to be deployed at industrial scales as part of carbon capture and utilization strategies. Since the approach itself is relatively simple, it could lead to a more cost-effective and efficient solution. It also worked well with multiple catalyst types, including zinc oxide, copper oxide and bismuth oxide, which are allo used to target different CO2RR products.

“Our method addresses a long-standing obstacle with a low-cost, easily implementable solution,” Ahmad Elgazzar, co-first author and graduate student in chemical and biomolecular engineering at Rice, added in the release. “It’s a step toward making carbon utilization technologies more commercially viable and more sustainable.”

A team led by Wang and in collaboration with researchers from the University of Houston also recently shared findings on salt precipitation buildup and CO2RR in a recent edition of the journal Nature Energy.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

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