Houston is among the top cities for veteran entrepreneurs. Photo via Getty Images

Houston has moved up the ranks in an annual study of the top places in the U.S. for veteran entrepreneurs.

The study, conducted by the PenFed Foundation and Edelman Data & Intelligence, puts Houston at No. 5 among the best metro areas for veteran entrepreneurs. That’s up from No. 12 in the 2021 study.

The study cites Houston’s economic growth, support for veterans, strong employment, and low unemployment rate among veterans as factors favoring veteran entrepreneurs.

More than 300,000 military veterans live in the Houston area. That’s the second largest population of veterans in the U.S.

Due to the Houston area’s robust veteran population, Bayou City was chosen in 2018 as the site for the third local chapter of Bunker Labs, an accelerator and incubator for military-affiliated entrepreneurs.

At No. 1 in the study is Washington, D.C., followed by:

2. New York City
3. Seattle
4. Dallas-Fort Worth
5. Houston
6. Austin
7. Sioux Falls, South Dakota
8. Cleveland
9. Rapid City, South Dakota
10. Boston

Elsewhere in Texas, McAllen-Edinburg-Mission landed at No. 20 and San Antonio at No. 23.

The study analyzed four categories for each city: livability, economic growth, support for veterans, and ability to start a business. The study evaluated 390 metro areas.

“As the nation navigates the economic impacts of inflation, the study focused especially on how inflation impacts cities differently,” says the PenFed Foundation, established by PenFed Credit Union.

This is the third year for the study.

“We want to help cities across the United States understand which environments are best suited for military veterans to start and grow businesses, and inspire city leaders to take the actions needed to support veteran entrepreneurs,” James Schenck, president and CEO of PenFed Credit Union and CEO of the foundation, says in a news release.

Three Houston companies will pitch in Rice University's competition for veteran-owned startups. Courtesy of Rice University

3 Houston startups to compete in Rice University's Veterans Business Battle

It's on.

Rice University will soon play host to its 2019 Veterans Business Battle, where 20 veteran-owned companies — three of which are from Houston — will pitch their business models and compete for prize money and investment offers.

On April 12, the 20 semifinalists will pitch to a panel of investors, who will choose the top five. Those finalists will pitch the next ay, April 13, in hopes of taking home some of the awards.

"We are very excited about the great group of companies that are coming to Houston next month," says event co-chairman Asad Akram in a release. "It's our goal to introduce them to a network that can help their businesses grow and succeed."

The Houston-based companies competing are Amor Oral, Welcome Connect and FeedMe Fitness, according to a release from Rice University. Amor Oral specializes in the manufacturing and sale of edible, organic personal lubricants. The company's lubricants are all water-based, and Amor Oral claims to offer the largest selection of flavored personal lubricants in the U.S.

FeedMe Fitness, another Houston competitor, is a subscription service that offers customized workouts and meal plans to its subscribers. Welcome Connect is a real estate platform that connects real estate agents with prospective buyers.

More than $3 million has been invested in veteran-owned businesses since the competition's launch in 2015. All the competitors are ultimately after the same thing: investments that will help them launch or expand. The competitor pool includes newly launched ventures and owner-operated businesses, per the Rice release, and all semifinalists can potentially receive investment offers.

A handful of competitors are from Texas. Those competitors include the Dallas-based companies And I Like It and City Gym, Floresville-based Harvard Telemedicine, Fort Worth-based Harvest Returns, Wimberly-based Power Polymer, Corpus Christ-based Rock N Roe Aquaponics, and Bryan-based Zanbazan.

The remaining competitors from around the U.S. are:

  • Gotta Have It Fan Foams, from Springfield, Virginia
  • Family Proud, from San Diego
  • High Country Air Service, from Albuquerque, New Mexico
  • Knifehand Nutrition, from Syracuse, New York
  • Maco, from New York
  • Off Duty Blue, from Syracuse, New York
  • Randian, from Los Angeles
  • Reimbi, from Portland, Oregon
  • Safe Stamp, from Nashville
  • SEE ID, from Newcastle, Washington
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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.