Three Houston companies are going into the semifinals of Cleantech.org's competition. Photo via Getty Images

Three Houston energy startups are in the running for the $100,000 cash prize in Cleantech.org's GS Beyond Energy Innovation Challenge.

Amperon Holdings, Cemvita Factory, and Veloce Energy are among the competition's 24 semifinalists, which were announced June 17. Five semifinalists will be chosen to pitch their concepts during a virtual event July 21, and then the winner of the $100,000 prize will be named.

"This is not like the cleantech sector was 10 years ago. Getting down to 24 [semifinalists] was hard. Getting down to five finalists will be extremely challenging," Neal Dikeman, chairman and founder of Cleantech.org and a partner at one of the prize sponsors, Houston-based Energy Transition Ventures, says in a news release.

Amperon, with an office in Houston and headquarters in New York City, is a semifinalist in the "digitization of energy" category. The company, founded in 2017, builds real-time electricity demand tools for utilities, energy retailers, grid operators, and institutional traders. So far, Amperon has raised $4.3 million in funding, according to Crunchbase.

Houston-based Cemvita, founded in 2017 by siblings Tara and Moji Karimi, is a semifinalist in the "new fuels" category. Its biotechnology transforms carbon dioxide emissions into sustainable chemicals and polymers. In a recent interview for the Houston Innovators Podcast, Moji Karimi explained how unprecedented his work is — and how ready for collaboration his team is.

"There weren't biotech companies working with oil and gas companies for this use case that we have now," Karimi says. "We're defining this new category for application of synthetic biology in heavy industries for decarbonization."

Veloce, with an office in Houston and headquarters in Los Angeles, is a semifinalist in the "e-mobility in cities" category. The company, founded in 2020, aims to make installation of electric vehicle charging stations cheaper and faster. Veloce is an inaugural member of Greentown Houston, an incubator for climate technology startups.

Greentown Labs has announced its inaugural batch of members for its new Houston location. Photo via greentownlabs.com

New-to-Houston cleantech incubator names inaugural members

to the lab

A Somerville, Massachusetts-based cleantech accelerator has announced the 16 startups that will be a part of its new Houston incubator program.

Greentown Labs named the companies in the cohort this week just a few weeks after announcing the location of its new lab and workspace. The 40,000-square-foot space is being renovated from a former grocery store and is expected to open next spring.

"These early-access members are innovating across the key greenhouse gas-emitting sectors—including electricity, manufacturing, buildings, and more—and their solutions are helping create a sustainable future for all," reads a blog post on the company's website.

Here are Greentown Houston's inaugural members:

  • Austin-based Applied Bioplastics is creating affordable plastic alternatives with plant matter to help reduce consumers' carbon footprint.
  • Black Mountain Metals, based in Fort Worth, is focused on nickel and copper mining for lithium-ion battery cathodes.
  • Carbon Free Technologies created a home battery system that can store electricity when rates are low.
  • ClearValue uses pure hydrogen and oxygen as a sustainable power system.
  • e^2: equitable energy is described as a "multi-brand cause-marketing platform" that connects consumers to sustainable energy solutions through promotion and incentivization.
  • Eclipse Solar Projects builds, owns, and operates solar projects across the country through new technology and battery storage operations.
  • Houston-based Ennuity Holdings allows users to have access to solar energy subscription service — even though they don't have access to installing panels themselves.
  • Excipicio Energy , based in Houston, is taking renewable energy offshore by integrating wind, wave, and more into a single floating platform.
  • Houston-based Quantum New Energy platform, EnerWisely, helps people and companies make smart energy choices "to maximize their monetary savings and reduce their environmental impacts."
  • Spring, Texas-based Renu Energy is creating sustainable change through waste recycling and community engagement, according to its website.
  • REVOLUTION Turbine Technologies, based in North Carolina, is working on a power generator that can be used in the offshore setting.
  • Houston-based Revterra is developing a long-duration energy storage solution.
  • Skylark, based in Houston, created a "broadband last-mile radio systems for internet service providers, with a focus on 40 million unserved Americans in rural markets."
  • Austin-based swytchX is working on a cloud-based SaaS solution that uses blockchain technology to optimize renewable energy delivery.
  • Houston-based Varea Energy, a software company, uses data to build business models focusing on eliminating barriers to green initiatives.
  • California-based Veloce Energy develops faster electric vehicle charging infrastructure.
Companies interested in joining the incubator should reach out to Greentown Labs online.

The 16 startups will move into the Greentown space when it opens in the spring. Image via greentownlabs.com

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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.