Three Houston companies are going into the semifinals of Cleantech.org's competition. Photo via Getty Images

Three Houston energy startups are in the running for the $100,000 cash prize in Cleantech.org's GS Beyond Energy Innovation Challenge.

Amperon Holdings, Cemvita Factory, and Veloce Energy are among the competition's 24 semifinalists, which were announced June 17. Five semifinalists will be chosen to pitch their concepts during a virtual event July 21, and then the winner of the $100,000 prize will be named.

"This is not like the cleantech sector was 10 years ago. Getting down to 24 [semifinalists] was hard. Getting down to five finalists will be extremely challenging," Neal Dikeman, chairman and founder of Cleantech.org and a partner at one of the prize sponsors, Houston-based Energy Transition Ventures, says in a news release.

Amperon, with an office in Houston and headquarters in New York City, is a semifinalist in the "digitization of energy" category. The company, founded in 2017, builds real-time electricity demand tools for utilities, energy retailers, grid operators, and institutional traders. So far, Amperon has raised $4.3 million in funding, according to Crunchbase.

Houston-based Cemvita, founded in 2017 by siblings Tara and Moji Karimi, is a semifinalist in the "new fuels" category. Its biotechnology transforms carbon dioxide emissions into sustainable chemicals and polymers. In a recent interview for the Houston Innovators Podcast, Moji Karimi explained how unprecedented his work is — and how ready for collaboration his team is.

"There weren't biotech companies working with oil and gas companies for this use case that we have now," Karimi says. "We're defining this new category for application of synthetic biology in heavy industries for decarbonization."

Veloce, with an office in Houston and headquarters in Los Angeles, is a semifinalist in the "e-mobility in cities" category. The company, founded in 2020, aims to make installation of electric vehicle charging stations cheaper and faster. Veloce is an inaugural member of Greentown Houston, an incubator for climate technology startups.

Greentown Labs has announced its inaugural batch of members for its new Houston location. Photo via greentownlabs.com

New-to-Houston cleantech incubator names inaugural members

to the lab

A Somerville, Massachusetts-based cleantech accelerator has announced the 16 startups that will be a part of its new Houston incubator program.

Greentown Labs named the companies in the cohort this week just a few weeks after announcing the location of its new lab and workspace. The 40,000-square-foot space is being renovated from a former grocery store and is expected to open next spring.

"These early-access members are innovating across the key greenhouse gas-emitting sectors—including electricity, manufacturing, buildings, and more—and their solutions are helping create a sustainable future for all," reads a blog post on the company's website.

Here are Greentown Houston's inaugural members:

  • Austin-based Applied Bioplastics is creating affordable plastic alternatives with plant matter to help reduce consumers' carbon footprint.
  • Black Mountain Metals, based in Fort Worth, is focused on nickel and copper mining for lithium-ion battery cathodes.
  • Carbon Free Technologies created a home battery system that can store electricity when rates are low.
  • ClearValue uses pure hydrogen and oxygen as a sustainable power system.
  • e^2: equitable energy is described as a "multi-brand cause-marketing platform" that connects consumers to sustainable energy solutions through promotion and incentivization.
  • Eclipse Solar Projects builds, owns, and operates solar projects across the country through new technology and battery storage operations.
  • Houston-based Ennuity Holdings allows users to have access to solar energy subscription service — even though they don't have access to installing panels themselves.
  • Excipicio Energy , based in Houston, is taking renewable energy offshore by integrating wind, wave, and more into a single floating platform.
  • Houston-based Quantum New Energy platform, EnerWisely, helps people and companies make smart energy choices "to maximize their monetary savings and reduce their environmental impacts."
  • Spring, Texas-based Renu Energy is creating sustainable change through waste recycling and community engagement, according to its website.
  • REVOLUTION Turbine Technologies, based in North Carolina, is working on a power generator that can be used in the offshore setting.
  • Houston-based Revterra is developing a long-duration energy storage solution.
  • Skylark, based in Houston, created a "broadband last-mile radio systems for internet service providers, with a focus on 40 million unserved Americans in rural markets."
  • Austin-based swytchX is working on a cloud-based SaaS solution that uses blockchain technology to optimize renewable energy delivery.
  • Houston-based Varea Energy, a software company, uses data to build business models focusing on eliminating barriers to green initiatives.
  • California-based Veloce Energy develops faster electric vehicle charging infrastructure.
Companies interested in joining the incubator should reach out to Greentown Labs online.

The 16 startups will move into the Greentown space when it opens in the spring. Image via greentownlabs.com

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”