The Woodlands is the No. 4 best place to retire. Photo courtesy of Visit The Woodlands

Houston-area suburbs should be on the lookout for an influx of retirees in 2026. A new study by U.S. News and World Report has declared The Woodlands and Spring as the fourth and fifth best cities to retire in America, with three other local cities making the top 25.

The annual report, called "250 Best Places to Retire in the U.S. in 2026" initially compared 850 U.S. cities, and narrowed the list down to a final 250 cities (up from 150 previously). Each locale was analyzed across six indexes: quality of life for individuals reaching retirement age, value (housing affordability and cost of living), health care quality, tax-friendliness for retirees, senior population and migration rates, and the strength of each city's job market.

Midland, Michigan was crowned the No. 1 best place to retire in 2026. The remaining cities that round out the top five are Weirton, West Virginia (No. 2) and Homosassa Springs, Florida (No. 3).

According to U.S. News, about 15 percent of The Woodlands' population is over the age of 65. The median household income in this suburb is $139,696, far above the national average median household income of $79,466.

Though The Woodlands has a higher cost of living than many other places in the country, the report maintains that the city "offers a higher value of living compared to similarly sized cities."

"If you want to buy a house in The Woodlands, the median home value is $474,279," the city's profile on U.S. News says. "And if you're a renter, you can expect the median rent here to be $1,449." For comparison, the report says the national average home value is $370,489.

Spring ranked as the fifth best place to retire in 2026, boasting a population of more than 68,000 residents, 11 percent of whom are seniors. This suburb is located less than 10 miles south of The Woodlands, while still being far enough away from Houston (about 25 miles) for seniors to escape big city life for the comfort of a smaller community.

"Retirees are prioritizing quality of life over affordability for the first time since the beginning of the COVID-19 pandemic," said U.S. News contributing editor Tim Smart in a press release.

The median home value in Spring is lower than the national average, at $251,247, making it one of the more affordable places to buy a home in the Houston area. Renters can expect to pay a median $1,326 in monthly rent, the report added.

Elsewhere in Houston, Pearland ranked as the 17th best place to retire for 2026, followed by Conroe (No. 20) and League City (No. 25).

Other Texas cities that ranked among the top 50 best places to retire nationwide include Victoria (No. 12), San Angelo (No. 28), and Flower Mound (No. 37).

The top 10 best U.S. cities to retire in 2026 are:

  • No. 1 – Midland, Michigan
  • No. 2 – Weirton, West Virginia
  • No. 3 – Homosassa Springs, Florida
  • No. 4 – The Woodlands, Texas
  • No. 5 – Spring, Texas
  • No. 6 – Rancho Rio, New Mexico
  • No. 7 – Spring Hill, Florida
  • No. 8 – Altoona, Pennsylvania
  • No. 9 – Palm Coast, Florida
  • No. 10 – Lynchburg, Virginia
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This article originally appeared on CultureMap.com.

Chevron is one of the best places to work. Courtesy photo

11 Houston companies named best places to work by U.S. News

Best in the U.S.

Nearly a dozen public and private Houston-based companies have been hailed among the best places to work in 2025 by U.S. News and World Report.

The annual "U.S. News Best Companies to Work For" report examines thousands of publicly-traded companies around the world to determine the best employers based on six metrics including work-life balance and flexibility; quality of pay and benefits; job and company stability; career opportunities and professional development; and more. The companies were not ranked, but included based on reader surveys and publicly available data about each workplace.

New for the 2025-2026 ratings, U.S. News expanded its methodology to include privately owned companies and companies with internship opportunities for recent graduates and new, current, and prospective students. Companies were also grouped into job-specific and industry-specific lists, and the publication also added a new list highlighting "employers that are particularly friendly to employees who are also caregivers in their personal lives."

U.S. News included seven publicly-traded companies and four privately owned companies in Houston on the lists.

Chevron

It may not come as a surprise that oil and gas corporation Chevron landed at the top of the list of top public employers in the Energy Capital of the World. The energy giant currently employs more than 45,000 people, earns $193.47 billion in annual revenue, and has a market cap of $238.74 billion. The company earned high ratings by U.S. News for its job stability, "belongingness," and quality of pay.

Chevron also appeared in U.S. News' industry-specific "Best in Energy and Resources" list, the "Best Companies in the South" list, and the "Best for Internships" list.

American Bureau of Shipping (ABS)

In the category of privately held companies headquartered in Houston, American Bureau of Shipping (ABS) landed on top as one of the best employers thanks to its employee work-life balance, job stability, and quality of pay. U.S. News estimates ABS has between 5,000 and 10,000 employees, and generated between $1 billion to $10 billion in revenue in 2024.

This engineering and construction company was founded in 1862, and describes itself as "a global leader in providing classification services for marine and offshore assets."

"Our mission is to serve the public interest as well as the needs of our members and clients by promoting the security of life and property and preserving the natural environment," the company website says.

In addition to earning a place among U.S. News' overall "Best Companies" list, ABS also appeared in the "Best in Engineering and Construction" list.

Other top companies to work for in Houston include:

  • Calpine – Best in Energy and Resources; Best Companies (overall)
  • ConocoPhillips – Best in Energy and Resources; Best Companies (overall); Best in Caregiving; Best Companies in the South
  • Hines – Best in Real Estate and Facilities Management; Best Companies (overall)
  • Insperity, Kingwood – Best in Healthcare and Research; Best Companies (overall); Best in Caregiving; Best Companies in the South
  • KBR – Best in Engineering and Construction; Best Companies (overall); Best Companies in the South
  • Men's Warehouse – Best in Consumer Products; Best Companies (overall)
  • Occidental – Best in Energy and Resources; Best Companies (overall); Best Companies in the South
  • PROS – Best in Information Technology; Best Companies (overall); Best Companies in the South
  • Skyward Specialty Insurance – Best in Finance and Insurance; Best Companies (overall); Best Companies in the South
"'Best' is a subjective term relative to career satisfaction, and many aspects factor into someone’s decision to apply for a job with any given company," U.S. News said. "But some universally desired factors can contribute to a good workplace, such as quality pay, good work-life balance, and opportunities for professional development and advancement.

Other top Texas employers

In all, 30 employers headquartered in the Lone Star State made it onto U.S. News' 2025-2026 "Best Places to Work For" lists. Houston and the Dallas-Fort Worth metro area tied for the most employers make the list, at 11 companies each. Diamondback Energy in Midland was the only company from West Texas to make it on the list for the second year in a row.

The best places to work for across Dallas-Fort Worth:

  • Aimbridge Hospitality, Plano
  • Ben E. Keith, Fort Worth
  • Coach America, Grand Prairie
  • Digital Realty, Dallas
  • Freeman, Dallas
  • Integrity Marketing Group, Dallas
  • Lincoln Property Company, Dallas
  • RGP, Dallas
  • Sammons Enterprises, Dallas
  • Texas Instruments, Dallas
  • Veritex Community Bank, Dallas

The top companies to work for in Austin:

  • Cirrus Logic
  • Dell Technologies, Round Rock
  • Silicon Labs
  • Yeti

The top companies to work for in San Antonio:

  • Frost Bank
  • H-E-B
  • Sachry Group
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This article originally appeared on CultureMap.com.

Pearland is the No. 2 best place to live in the U.S. Photo via pearlandedc.com

2 Houston suburbs named among 10 best places to live by U.S. News & World Report

Where to Live

The Houston suburbs of Pearland and League City have landed among the top 10 best places to live in 2025, according to U.S. News & World Report.

New for the 2025-2026 "Best Places to Live in the U.S." rankings, U.S. News expanded its coverage from 150 to 250 U.S. cities, and updated its methodology to examine each city based on five livability indexes: Quality of life, value, desirability, job market, and net migration.

Pearland ranked No. 3 nationwide, earning a 7.0 score alongside No. 1-winning Johns Creek, Georgia and No. 2 winner Carmel, Indiana.

Pearland also landed on top of U.S. News separate rankings of the best places to live in Texas for 2025-2026.

Some facts about Pearland that put it at the top of the list include its median household income ($115,504), its median home values ($319,753), and its bustling population of nearly 124,000 residents.

Housing costs in Pearland are extremely attractive compared to other places in the country, as the national average home is worth over $370,000. It's no wonder this Houston neighbor has been adding more high-income households than many other places in Texas.

Pearland's population is a healthy mix of young individuals and families, with 29 percent of residents under 20 years old and 36 percent of the population between the ages of 20-44. Nearly a quarter of Pearland's population is between 45-64-years-old, while only 12 percent of residents are over 65, the report says.

Pearland's reputation as one of the safest cities in America is also boosting its community appeal.

Pearland Pear Trail Pearland's Pear-Scape Trail is a popular public art trail that residents, families, and visitors can enjoy. The sculptures are scattered all over the city.City of Pearland - Government/Facebook

"Finding a community to be part of can play a major role in making a place feel like home," U.S. News said. "If you’re a parent with young children, you may want to live in a neighborhood with other people in that phase of life. If you’re a professional moving to a hot job market for your field, you may want to live in an apartment close to the office or within walking distance of friends and colleagues."

Pearland also enjoys a better job market than other cities, the report added. Pearland's unemployment rate as of 2023 was only 3.6 percent, lower than the national average unemployment rate of 4.5 percent.

However, if people are looking for a public transportation-friendly city, they may need to look elsewhere. Almost all commuters in Pearland drive to their workplaces, making access to a vehicle absolutely necessary for living in the suburb. Pearland's 31.2-minute average commute time is also 9.2 minutes higher than the national average, U.S. News said.

Other Houston-area suburbs

League City ranked three spots behind Pearland as the 6th best place to live in the U.S., and No. 2 in Texas. The city boasts a median household income of $120,670, and affordable median home values at $327,511.

Workers in League City also predominantly rely on vehicles for their daily commutes, and only 3.7 percent of the population use public transport to get to work. Commuters spend an average time of 27.5 minutes driving to work, U.S. News determined.

More than half (63.5 percent) of all League City residents are married, and 54 percent of the population are between the ages of 25 and 64-years-old.

Here's how other Houston-area cities faired among the top 100:

  • No. 16 – Sugar Land
  • No. 44 – The Woodlands
  • No. 45 – Katy
  • No. 67 – Missouri City
  • No. 73 – Spring

Houston drops out of the top 100

Though Houston proper made substantial improvements to land among the top 100 best places to live in U.S. News' 2024-2025 report, the city has once again plummeted toward the bottom of the list for 2025-2026.

Houston slumped to No. 381 this year, and only ranked No. 63 in the statewide comparison, showing that the city has lost its charm in favor of its appealing suburban neighbors.

The top 10 best places to live in the U.S. are:

  • No. 1 – Johns Creek, Georgia
  • No. 2 – Carmel, Indiana
  • No. 3 – Pearland, Texas
  • No. 4 – Fishers, Indiana
  • No. 5 – Cary, North Carolina
  • No. 6 – League City, Texas
  • No. 7 – Apex, North Carolina
  • No. 8 – Leander, Texas
  • No. 9 – Rochester Hills, Michigan
  • No. 10 – Troy, Michigan
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This story originally appeared on CultureMap.com.

University of Houston earns four spots on U.S. News & World Report's rankings. Photo via uh.edu

9 Houston universities make U.S. News' list of best grad schools 2025

Top of the class

Nine Houston universities have climbed through the ranks in U.S. News & World Report’s recently released report of the best graduate schools nationwide for 2025. Several graduate programs also appeared among the top 10 in a Texas-wide comparison.

U.S. News published its annual national "Best Graduate Schools" rankings on April 8. They look at several programs including business, education, engineering, fine arts, health, and many others.

For the 2025 report, the publication added new Ph.D. social sciences and humanities program rankings in English, history, political science and sociology for the first time since 2021. U.S. News also ranked graduate economics and psychology programs in the social sciences and the humanities for the first time since 2022.

Among the newcomers are Houston Christian University and Texas Southern University.

Here's how the nine local schools ranked, statewide and nationally, and how they compared with last year's national ranking:

University of Houston

  • No. 4 best graduate engineering school in Texas; No. 72 nationally
  • No. 5 best graduate education school in Texas; No. 81 nationally (down from No. 63 last year)
  • No. 5 best law school in Texas; No. 63 nationally (up from No. 68)

The University of Houston Law Center has the No. 9 best health law program in the nation, and ranked No. 15 for its legal writing program. The university's part-time MBA program ranked No. 38 nationally

University of Houston, Clear Lake

  • No. 12 best graduate education school in Texas; No. 166 nationally

The Clear Lake branch of the University of Houston tied for No. 166 for its part-time MBA program.

Houston Christian University

  • No. 21 best graduate education school in Texas; tied for No. 234-258 nationally

University of Texas Health Science Center

  • No. 1 best Doctor of Nursing Practice program in Texas; No. 33 nationally (up from No. 45)
  • No. 2 best graduate nursing program in Texas; No. 41 nationally (down from No. 31)

Prairie View A&M University, Northwest Houston Center

  • No. 5 best graduate nursing program in Texas; No. 104 nationally (up from No. 117)
  • No. 7 best Doctor of Nursing Practice program in Texas; tied for No. 143-158 nationally

Rice University

  • No. 2 best graduate business school in Texas; No. 29 nationally (unchanged)
  • No. 3 best graduate engineering school in Texas; No. 26 nationally

Rice's entrepreneurship program is the 9th best in the country, and its part-time MBA program ranked 13th nationally. The George R. Brown School of Engineering earned nods for its No. 10-ranking biomedical engineering and environmental engineering programs.

University of Texas Medical Branch, Galveston

  • No. 5 best Doctor of Nursing Practice program in Texas; No. 76 nationally

South Texas College of Law Houston

  • No. 7 best law school in Texas; No. 138 nationally

Out of the 11 law programs ranked by U.S. News, the South Texas College of Law performed the best for its trial advocacy (No. 12), dispute resolution law (No. 23), and legal writing (No. 51) programs.

Texas Southern University

  • No. 10 best law school in Texas; tied for No. 178-195 nationally

More specifically, TSU has the 64th best trial advocacy law program in the nation, U.S. News said.

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This article originally appeared on our sister site, CultureMap.com.

Several Houston-area schools earned top spots in U.S. News & World Report's 2025 rankings for best elementary and middle schools in Texas. Photo via Getty Images

Houston schools shine on annual ranking of top institutions for 2025

best in class

Several Houston elementary and middle schools are at the top of the class when it comes to educating and preparing the next generation for a successful life and career, according to U.S. News & World Report's just-released list of 2025 Elementary and Middle Schools Rankings.

One such school – T.H. Rogers School in Houston ISD – is the No. 8 best middle school in Texas for 2025.

U.S. News ranked over 79,000 public schools on the state and district level using data from the U.S. Department of Education. Schools were analyzed based on their students' proficiencies in mathematics and reading/language arts on state assessments, and tie-breakers were decided based on student-teacher ratios.

Texas' best middle schools for 2025

Three Houston middle schools achieved spots among the top 10 best Texas middle schools for 2025, according to U.S. News.

T.H. Rogers School has a total enrollment of 1,063 students, with 87 percent of the student population scoring "at or above the proficient level" in mathematics, and 90 percent proficiency in reading. The school has a student-teacher ratio of 17:1, with 62 full-time teachers.

T.H. Rogers School also topped the district-wide list as the No. 1 best middle school in HISD.

Houston Gateway Academy - Coral Campus also ranked among the statewide top 10, coming in at No. 9 with a total enrollment of 914 students. U.S. News says 82 percent of HGA students are proficient in math, and 80 percent are proficient in reading.

"Houston Gateway Academy - Coral Campus did better in math and better in reading in this metric compared with students across the state," U.S. News said in the school's profile. "In Texas, 51 percent of students tested at or above the proficient level for reading, and 41 percent tested at or above that level for math."

Right behind HGA to round out the top 10 best Texas middle schools is Houston ISD's Briarmeadow Charter School. This middle school has 600 students, 69 percent of which are proficient in math and 74 percent are proficient reading.

Briarmeadow's student-teacher ratio is 16:1, which is better than the district-wide student-teacher ratio, and it employs 38 full-time teachers.

U.S. News also ranked Briarmeadow as the second best middle school in Houston ISD.

Six additional Houston-area schools ranked among the top 25 best middle schools in Texas, including:

  • No. 18 – Cornerstone Academy, Spring Branch ISD
  • No. 19 – Mandarin Immersion Magnet School, Houston ISD
  • No. 21 – Smith Middle School, Cypress-Fairbanks ISD
  • No. 22 – Seven Lakes Junior High, Katy ISD
  • No. 23 – Houston Gateway Academy
  • No. 25 – Beckendorff Junior High, Katy ISD

The best elementary schools in Texas

Jesus A. Kawas Elementary school in Laredo was crowned the No. 1 elementary school in Texas for 2025, while two Houston-area schools made it into the top 10.Tomball ISD's Creekside Forest Elementary in The Woodlands is the No. 7 best elementary school statewide, boasting 656 students, 42 full-time teachers, and one full-time counselor. Students at this school, which U.S. News designates is situated in a "fringe rural setting," scored 90 percent efficiency in math and 94 percent efficiency in reading.Following one spot behind Creekside Forest in the statewide ranking is Sugar Land's Commonwealth Elementary School in Fort Bend ISD, coming in at No. 8. Commonwealth has a student population of 954 with 55 full-time teachers, and two full-time counselors. The school's student-teacher ratio is 17:1, and 90 percent of students are proficient in math, and 94 percent in reading.U.S. News says student success at Commonwealth is significantly higher than the rest of Fort Bend ISD."In Fort Bend Independent School District, 59 percent of students tested at or above the proficient level for reading, and 47 percent tested at or above that level for math," U.S. News said in Commonwealth's profile. "Commonwealth Elementary [also] did better in math and better in reading in this metric compared with students across the state."Other Houston-area schools that were ranked among the 25 best in Texas are:
  • No. 13 – Bess Campbell Elementary, Sugar Land, Lamar CISD
  • No. 20 – West University Elementary, Houston ISD
  • No. 23 – T.H. Rogers School, Houston ISD
  • No. 25 – Griffin Elementary, Katy ISD

"The 2025 Best Elementary and Middle Schools rankings offer parents a way to evaluate how schools are providing a high-quality education and preparing students for future success," said LaMont Jones, Ed.D., the managing editor for Education at U.S. News. "The data empowers families and communities to advocate for their children’s education. Research continues to indicate that how students perform academically at these early grade levels is a big factor in their success in high school and beyond."

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This article originally ran on CultureMap.

The Ivy League of the South has done it once again. Photo via Rice University

Houston's Rice University tops new 2025 list of best colleges in Texas

report

The most prestigious higher education institution in Houston has done it again: Rice University has topped WalletHub's 2025 list of the best colleges and universities in Texas for 2025.

The just-released list analyzed more than 800 colleges and universities in the United States using 30 metrics to determine their rankings.

Rice claimed the No. 1 spot in Texas and in WalletHub's regional category of best universities in the South. The school also ranked as the No. 6 best college nationwide.

Rice earned first place in the category for the "best" (or lowest) on-campus crime rates, and ranked 13th for its gender and racial diversity. The school ranked No. 24 in the category for net cost. According to U.S. News and World Report, tuition and fees at Rice cost $60,709 per year. Rice also has an acceptance rate of eight percent, earning the university No. 27 in the category for admission rates.

Here's how WalletHub broke down the rest of Rice's ranking, where No. 1 is the best and No. 49 is the worst:

  • No. 26 – Student-faculty ratio
  • No. 43 – Graduation rate
  • No. 47 – Post-attendance median salary
Rice's recent accolades add to an ongoing winning streak of high rankings. In September, the private university ranked as the No. 1 best Texas college for 2025 by U.S. News, and ranked No. 18 nationally. Education information and review platform Niche also recently ranked Rice the 15th best college in the country and the No. 1 best in Texas for 2025. And Forbes named Rice No. 9 in its 2024-25 list of top U.S. colleges.In the spring, Rice's Jesse H. Jones Graduate School of Business ranked No. 2 in the national publication's ranking of the best graduate schools in Texas.

The only other Houston university to earn a spot in WalletHub's report was the University of Houston, earning No. 12 in Texas and No. 288 nationally.

The top five universities that outranked Rice in the national rankings were Princeton University (No. 1), Yale University (No. 2), Harvard University (No. 3), Massachusetts Institute of Technology (No. 4), and Dartmouth College (No. 5).

The top 10 colleges and universities in Texas are:

  • No. 1 – Rice University
  • No. 2 – The University of Texas at Austin
  • No. 3 – Trinity University
  • No. 4 – Texas A&M University-College Station
  • No. 5 – Southwestern University
  • No. 6 – Texas Christian University
  • No. 7 – Austin College
  • No. 8 – Texas A&M International University
  • No. 9 – University of Dallas
  • No. 10 – Southern Methodist University
The full report can be found on wallethub.com

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This article originally ran on CultureMap.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”