Meet Commander Reid Wiseman, the responsible for the success of the Artemis II mission once it launches. Photo courtesy of NASA

The world now knows the names of the four Houston-based astronauts who will launch in the first crewed moon mission in 50 years. NASA's Artemis II will see the first woman and person of color helming a lunar voyage, a first since the agency's history.

Astronaut Christina Hammock Koch, herself part of a history-making astronaut class and first all-female spacewalk— will join Victor Glover — the first person of color heading to the moon. Rookie Canadian astronaut Jeremy Hansen rounds out the crew with Commander Reid Wiseman.

Building on the unmanned Artemis I mission to the moon that concluded in December, Artemis II is slated to launch around November 2024, per NASA. In a scene familiar to space fans, the Artemis II crew will deploy inside the cozy Orion spacecraft that will sit atop the Space Launch System (SLS) rocket from Kennedy Space Center in Florida.

Artemis II's crew will spend some 10 days in orbit and even venture farther than the 1.4 million miles logged by Artemis I, adding to the historic nature of the journey. After moon orbit, the spacecraft will return to Earth for splashdown and recovery — always a celebrated moment after the highly anticipated takeoff.

Data gathered from Artemis II will pad information from Artemis I in effort to create a permanent moon outpost. On the moon, crews will learn how to live and work away from Earth, which will pave the way for the eventual mission to Mars. A planned Artemis III mission may launch in 2025 or '26, per NASA, which picks up from the last trip, Apollo 17 in 1972. The Artemis III mission, NASA promises, will see the first woman and person of color on the moon.

CultureMap caught up with a very busy Wiseman, who is now responsible for the success of the Artemis II mission once it launches. Hailing from Baltimore, Maryland, the 47-year-old earned his master's degree from Johns Hopkins University and is a decorated naval aviator, serving in the Middle East as a fighter pilot. The Artemis II mission commander completed a 165-day trip to the International Space Station in 2014 and was most recently chief of the astronaut office, per his bio. He has two sons with wife Carol, who passed away from cancer in May 2020.

The Artemis II crew was announced earlier this week. Photo courtesy of NASA

CultureMap: Congratulations, Commander. As Artemis II's leader, you are joining lunar mission commander names like the first man on the moon, Neil Armstrong, and Apollo 13's Jim Lovell. Do you allow yourself to think like that?

Reid Wiseman: Thank you. I do not allow myself to think like that. I think if you get to meet this crew — Victor Glover, Christina Koch, Jeremy Hanson — I really think we would say we want this to be so routine. We want Artemis II to be so successful and so long term that people completely forget about us. We're just that initial little stepping stone. I really hope that's the case. I am flying with an incredible group of heroes and I can't wait to go get this job done.

CM: What does it mean, as mission commander, to have the safety — and the lives — of these amazing and history-making astronauts in your hands once you launch?

RW: It means everything to me.

CM: You and the crew are so incredibly accomplished in your own individual spaces. Yet when you get to NASA — as Christina Koch once told me — you're kind of learning anew. What are you learning now?

RW: When you look at our crew, our next step is to learn about the spacecraft that will be operating in deep space. It's a very capable, very redundant, robust machine. So we have to get in the classroom, we've got to learn about all the capabilities, but we also have to get out and see the workforce.

We'll be the first humans to ever ride on this vehicle. And there's a lot of unknowns. We have a lot of systems to test. Uh One was very successful.

We need to hit the books and then we need to get in the sim [simulator], we need to practice simulations, learn how we all operate together as a team and then learn about the failure modes of the vehicle, how we can work around to keep ourselves safe and keep the mission going. And then after that, I think we'll be ready to look at Florida — and head out to the moon.

CM: Do prior lunar flight commanders and icons — like Armstrong and Lovell — serve as role models? How about the astronaut network in general?

RW: I think we look at those legends as their heroes, but they are also friends. Those folks really gave their lives to our nation and when they landed on the moon for the first time. But the amazing part for us as younger astronauts is they're still heavily engaged in everything we do right now.

I talked to Jack [Harrrison] Schmitt just a few months ago. Dave Scott still comes by every time he can to talk about geologic processes on the moon. Like these guys are our friends. It's really, really neat.

Neil Armstrong was amazing. John Young was incredible — he led our office for a number of years. Those guys are heroes to us for sure. When you look at who has taught me the most about being an astronaut, it's the folks I flew with on my first mission. It's the folks that I've worked with in the astronaut office. Now, I've seen some exceptional examples of leadership and followership and both skills are critical to be an astronaut.

CM: You learned you'll be headed to the moon — the dream adventure of billions all over the world— in the most office kind of way, we hear.

RW: Uh yeah, we all goofed up [laughs]. We missed the meeting. The chief astronaut put a placeholder on my schedule for a different topic. I was actually at a doctor's office and the doctor just walked in. So, I missed the first part of the meeting and I was able to use Microsoft Teams and dial in towards the end.

When the camera popped up, I saw the chief astronaut — who I expected to see for my meeting. But then, I also saw Norm Knight, our director of flight operations. I also saw Victor Glover and Christina Koch. And I was like, ‘oh boy, I think I just missed something big here.’

CM: Well, we've all missed meetings. But this was big — like headed to the moon big.

RW: Right [laughs]. It turned out that both Christina and Victor also missed the beginning of the meeting. So, we all showed up in perfect harmony.

------

This article originally ran on CultureMap.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.