Turns out, everyone wants to live here. Photo via Getty Images

Houston is the fourth most populous U.S. city, and saw the ninth largest numeric population gain of any U.S. city in 2022, according to the U.S. Census Bureau's latest findings.

From July 2021 to July 2022, Houston added 11,223 new residents, bringing its total population to 2,302,878. By comparison, San Antonio (population just under 1.5 million) is the seventh largest.

Harris County also led the way with the highest numeric gains for housing units in the nation, at 32,694, coinciding with recent reports deeming Houston the most active real estate market within the last decade.

Together, Houston-The Woodlands-Sugar Land ranked No. 5 in the list of the 10 most populous U.S. metro areas (as opposed to the cities, themselves). Dallas-Fort Worth-Arlington ranked one place higher at No. 4.

Texas cities and towns dominated every list in the new Census Bureau report. "Texas was the only state that had more than three cities on both the 15 fastest-growing large cities and towns by numeric change and by percent change lists," the report says.

Fastest-growing cities
Six out of the 15 fastest-growing cities in the United States are in Texas, and with one Houston suburb – Conroe – landing at No. 11. Conroe had an 6.3 percent population increase from July 2021 to July 2022, bringing the city's total population just over 101,400.

The north Austin suburb of Georgetown had the highest growth rate in the nation, at 14.4 percent, bringing the city's total population to more than 86,500 residents. Surrounding Austin suburbs Kyle and Leander landed in No. 3 and No. 4 with the same population growth rate of 10.9 percent.

The not-so-little Dallas suburb Little Elm zoomed all the way up to No. 5 with an 8 percent population increase, bringing the city's total population to more than 55,300 residents. New Braunfels, which is outside San Antonio, came in at No. 13.

The top 15 fastest-growing large cities in the U.S. are:

  • No. 1 – Georgetown, Texas
  • No. 2 – Santa Cruz, California
  • No. 3 – Kyle, Texas
  • No. 4 – Leander, Texas
  • No. 5 – Little Elm, Texas
  • No. 6 – Westfield, Indiana
  • No. 7 – Queen Creek, Arizona
  • No. 8 – North Port, Florida
  • No. 9 – Cape Coral, Florida
  • No. 10 – Port St. Lucie, Florida
  • No. 11 – Conroe, Texas
  • No. 12 – Maricopa, Arizona
  • No. 13 – New Braunfels, Texas
  • No. 14 – Lehi, Utah
  • No. 15 – Medford, Massachusetts
Largest population increases
When it comes to most populous cities overall, Texas takes five of the 15 top spots with Houston claiming No. 1 in the state. After Houston's No. 4 national rank with its population of over 2.3 million, San Antonio earned No. 7 with over 1.47 million residents, and Dallas at No. 9 with just under 1.3 million residents. Austin barely made it into the top 10 with over 974,000 residents, and Fort Worth ranked No. 13.

The top 15 most populous American cities are:

  • No. 1 – New York City
  • No. 2 – Los Angeles
  • No. 3 – Chicago
  • No. 4 – Houston
  • No. 5 – Phoenix
  • No. 6 – Philadelphia
  • No. 7 – San Antonio, Texas
  • No. 8 – San Diego, California
  • No. 9 – Dallas
  • No. 10 – Austin, Texas
  • No. 11 - Jacksonville, Florida
  • No. 12 - San Jose, California
  • No. 13 - Fort Worth, Texas
  • No. 14 - Columbus, Ohio
  • No. 15 - Charlotte, North Carolina

Greatest housing growth
The report also discovered that housing inventory skyrocketed by 1.6 million units between 2021 and 2022. Texas had the third fastest housing growth with a rate of 2.3 percent, versus Utah, which had the fastest growth at 3.3 percent.

In addition to Harris County, the only other Texas county that made the top five for the highest housing growth was Travis (No. 3).

The full report can be found on census.gov.

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This article originally ran on CultureMap.

Texas added more residents from mid-2018 through mid-2019 than any other state. Marco Bicci/Getty Images

Texas added more residents than any other state in past year

Growing gains

Yes, everything is bigger in Texas — including population growth. From mid-2018 to mid-2019, the Lone Star State added more residents than any other state, new estimates from the U.S. Census Bureau show.

From July 2018 to July 2019, the population of Texas grew by 367,215, according to Census Bureau data released December 30. That's close to the number of people who live in the Dallas-Fort Worth suburb of Arlington (398,112).

Keep in mind that this does not mean nearly 370,000 people moved to Texas in just one year. The Census Bureau's new population estimates represent the number of people who moved to and moved out of each state, as well as the number of births versus deaths.

Texas' 2018-19 population growth eclipsed that of the country's largest state, California.

The Golden State saw its population increase by just 50,635 during the one-year period, the Census Bureau says. What's behind the meager growth? From 2018 to 2019, California's net domestic migration plunged by 203,414. Net domestic migration represents the number of people moving to a state versus the number of people moving out of a state.

Here's another eye opener: Texas accounted for nearly one-fourth of the country's population growth from 2018 to 2019 (1,552,022 people). In that time, 10 states lost population, including Illinois, New Jersey, and New York.

In July 2018, the Texas population stood at an estimated 28,628,666. By July 2019, that figure had climbed to 28,995,881, the Census Bureau says. On a percentage basis, Texas' 2018-19 population growth (1.28 percent) ranked fifth among the states.

Perhaps more impressive is how much Texas expanded from April 2010 (when the last official U.S. headcount was conducted) to July 2019. During that period, Texas added 3,849,790 residents, according to the Census Bureau. To put that into perspective, nearly 4 million people live in the entire state of Oklahoma. Texas' population jumped 15.3 percent from 2010 to 2019, the third highest growth rate behind the District of Columbia and Utah.

Experts cite economic and job growth — along with a low cost of living, a low cost of doing business, and low taxes compared with many other states — as drivers of Texas' population boom. Helping fuel the boom are substantial population spikes in the state's four largest metro areas: Austin, Dallas-Fort Worth, Houston, and San Antonio.

In 2030, the state's population is projected to approach 34.9 million, according to a forecast from the Texas Demographic Center.

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This article originally ran on CultureMap.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.