Houston named 4th most populous city in U.S. — with the greatest housing growth — in new Census report

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Turns out, everyone wants to live here. Photo via Getty Images

Houston is the fourth most populous U.S. city, and saw the ninth largest numeric population gain of any U.S. city in 2022, according to the U.S. Census Bureau's latest findings.

From July 2021 to July 2022, Houston added 11,223 new residents, bringing its total population to 2,302,878. By comparison, San Antonio (population just under 1.5 million) is the seventh largest.

Harris County also led the way with the highest numeric gains for housing units in the nation, at 32,694, coinciding with recent reports deeming Houston the most active real estate market within the last decade.

Together, Houston-The Woodlands-Sugar Land ranked No. 5 in the list of the 10 most populous U.S. metro areas (as opposed to the cities, themselves). Dallas-Fort Worth-Arlington ranked one place higher at No. 4.

Texas cities and towns dominated every list in the new Census Bureau report. "Texas was the only state that had more than three cities on both the 15 fastest-growing large cities and towns by numeric change and by percent change lists," the report says.

Fastest-growing cities
Six out of the 15 fastest-growing cities in the United States are in Texas, and with one Houston suburb – Conroe – landing at No. 11. Conroe had an 6.3 percent population increase from July 2021 to July 2022, bringing the city's total population just over 101,400.

The north Austin suburb of Georgetown had the highest growth rate in the nation, at 14.4 percent, bringing the city's total population to more than 86,500 residents. Surrounding Austin suburbs Kyle and Leander landed in No. 3 and No. 4 with the same population growth rate of 10.9 percent.

The not-so-little Dallas suburb Little Elm zoomed all the way up to No. 5 with an 8 percent population increase, bringing the city's total population to more than 55,300 residents. New Braunfels, which is outside San Antonio, came in at No. 13.

The top 15 fastest-growing large cities in the U.S. are:

  • No. 1 – Georgetown, Texas
  • No. 2 – Santa Cruz, California
  • No. 3 – Kyle, Texas
  • No. 4 – Leander, Texas
  • No. 5 – Little Elm, Texas
  • No. 6 – Westfield, Indiana
  • No. 7 – Queen Creek, Arizona
  • No. 8 – North Port, Florida
  • No. 9 – Cape Coral, Florida
  • No. 10 – Port St. Lucie, Florida
  • No. 11 – Conroe, Texas
  • No. 12 – Maricopa, Arizona
  • No. 13 – New Braunfels, Texas
  • No. 14 – Lehi, Utah
  • No. 15 – Medford, Massachusetts
Largest population increases
When it comes to most populous cities overall, Texas takes five of the 15 top spots with Houston claiming No. 1 in the state. After Houston's No. 4 national rank with its population of over 2.3 million, San Antonio earned No. 7 with over 1.47 million residents, and Dallas at No. 9 with just under 1.3 million residents. Austin barely made it into the top 10 with over 974,000 residents, and Fort Worth ranked No. 13.

The top 15 most populous American cities are:

  • No. 1 – New York City
  • No. 2 – Los Angeles
  • No. 3 – Chicago
  • No. 4 – Houston
  • No. 5 – Phoenix
  • No. 6 – Philadelphia
  • No. 7 – San Antonio, Texas
  • No. 8 – San Diego, California
  • No. 9 – Dallas
  • No. 10 – Austin, Texas
  • No. 11 - Jacksonville, Florida
  • No. 12 - San Jose, California
  • No. 13 - Fort Worth, Texas
  • No. 14 - Columbus, Ohio
  • No. 15 - Charlotte, North Carolina

Greatest housing growth
The report also discovered that housing inventory skyrocketed by 1.6 million units between 2021 and 2022. Texas had the third fastest housing growth with a rate of 2.3 percent, versus Utah, which had the fastest growth at 3.3 percent.

In addition to Harris County, the only other Texas county that made the top five for the highest housing growth was Travis (No. 3).

The full report can be found on census.gov.

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This article originally ran on CultureMap.

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Texas added more residents from mid-2018 through mid-2019 than any other state. Marco Bicci/Getty Images

Texas added more residents than any other state in past year

Growing gains

Yes, everything is bigger in Texas — including population growth. From mid-2018 to mid-2019, the Lone Star State added more residents than any other state, new estimates from the U.S. Census Bureau show.

From July 2018 to July 2019, the population of Texas grew by 367,215, according to Census Bureau data released December 30. That's close to the number of people who live in the Dallas-Fort Worth suburb of Arlington (398,112).

Keep in mind that this does not mean nearly 370,000 people moved to Texas in just one year. The Census Bureau's new population estimates represent the number of people who moved to and moved out of each state, as well as the number of births versus deaths.

Texas' 2018-19 population growth eclipsed that of the country's largest state, California.

The Golden State saw its population increase by just 50,635 during the one-year period, the Census Bureau says. What's behind the meager growth? From 2018 to 2019, California's net domestic migration plunged by 203,414. Net domestic migration represents the number of people moving to a state versus the number of people moving out of a state.

Here's another eye opener: Texas accounted for nearly one-fourth of the country's population growth from 2018 to 2019 (1,552,022 people). In that time, 10 states lost population, including Illinois, New Jersey, and New York.

In July 2018, the Texas population stood at an estimated 28,628,666. By July 2019, that figure had climbed to 28,995,881, the Census Bureau says. On a percentage basis, Texas' 2018-19 population growth (1.28 percent) ranked fifth among the states.

Perhaps more impressive is how much Texas expanded from April 2010 (when the last official U.S. headcount was conducted) to July 2019. During that period, Texas added 3,849,790 residents, according to the Census Bureau. To put that into perspective, nearly 4 million people live in the entire state of Oklahoma. Texas' population jumped 15.3 percent from 2010 to 2019, the third highest growth rate behind the District of Columbia and Utah.

Experts cite economic and job growth — along with a low cost of living, a low cost of doing business, and low taxes compared with many other states — as drivers of Texas' population boom. Helping fuel the boom are substantial population spikes in the state's four largest metro areas: Austin, Dallas-Fort Worth, Houston, and San Antonio.

In 2030, the state's population is projected to approach 34.9 million, according to a forecast from the Texas Demographic Center.

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This article originally ran on CultureMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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