Turns out, everyone wants to live here. Photo via Getty Images

Houston is the fourth most populous U.S. city, and saw the ninth largest numeric population gain of any U.S. city in 2022, according to the U.S. Census Bureau's latest findings.

From July 2021 to July 2022, Houston added 11,223 new residents, bringing its total population to 2,302,878. By comparison, San Antonio (population just under 1.5 million) is the seventh largest.

Harris County also led the way with the highest numeric gains for housing units in the nation, at 32,694, coinciding with recent reports deeming Houston the most active real estate market within the last decade.

Together, Houston-The Woodlands-Sugar Land ranked No. 5 in the list of the 10 most populous U.S. metro areas (as opposed to the cities, themselves). Dallas-Fort Worth-Arlington ranked one place higher at No. 4.

Texas cities and towns dominated every list in the new Census Bureau report. "Texas was the only state that had more than three cities on both the 15 fastest-growing large cities and towns by numeric change and by percent change lists," the report says.

Fastest-growing cities
Six out of the 15 fastest-growing cities in the United States are in Texas, and with one Houston suburb – Conroe – landing at No. 11. Conroe had an 6.3 percent population increase from July 2021 to July 2022, bringing the city's total population just over 101,400.

The north Austin suburb of Georgetown had the highest growth rate in the nation, at 14.4 percent, bringing the city's total population to more than 86,500 residents. Surrounding Austin suburbs Kyle and Leander landed in No. 3 and No. 4 with the same population growth rate of 10.9 percent.

The not-so-little Dallas suburb Little Elm zoomed all the way up to No. 5 with an 8 percent population increase, bringing the city's total population to more than 55,300 residents. New Braunfels, which is outside San Antonio, came in at No. 13.

The top 15 fastest-growing large cities in the U.S. are:

  • No. 1 – Georgetown, Texas
  • No. 2 – Santa Cruz, California
  • No. 3 – Kyle, Texas
  • No. 4 – Leander, Texas
  • No. 5 – Little Elm, Texas
  • No. 6 – Westfield, Indiana
  • No. 7 – Queen Creek, Arizona
  • No. 8 – North Port, Florida
  • No. 9 – Cape Coral, Florida
  • No. 10 – Port St. Lucie, Florida
  • No. 11 – Conroe, Texas
  • No. 12 – Maricopa, Arizona
  • No. 13 – New Braunfels, Texas
  • No. 14 – Lehi, Utah
  • No. 15 – Medford, Massachusetts
Largest population increases
When it comes to most populous cities overall, Texas takes five of the 15 top spots with Houston claiming No. 1 in the state. After Houston's No. 4 national rank with its population of over 2.3 million, San Antonio earned No. 7 with over 1.47 million residents, and Dallas at No. 9 with just under 1.3 million residents. Austin barely made it into the top 10 with over 974,000 residents, and Fort Worth ranked No. 13.

The top 15 most populous American cities are:

  • No. 1 – New York City
  • No. 2 – Los Angeles
  • No. 3 – Chicago
  • No. 4 – Houston
  • No. 5 – Phoenix
  • No. 6 – Philadelphia
  • No. 7 – San Antonio, Texas
  • No. 8 – San Diego, California
  • No. 9 – Dallas
  • No. 10 – Austin, Texas
  • No. 11 - Jacksonville, Florida
  • No. 12 - San Jose, California
  • No. 13 - Fort Worth, Texas
  • No. 14 - Columbus, Ohio
  • No. 15 - Charlotte, North Carolina

Greatest housing growth
The report also discovered that housing inventory skyrocketed by 1.6 million units between 2021 and 2022. Texas had the third fastest housing growth with a rate of 2.3 percent, versus Utah, which had the fastest growth at 3.3 percent.

In addition to Harris County, the only other Texas county that made the top five for the highest housing growth was Travis (No. 3).

The full report can be found on census.gov.

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This article originally ran on CultureMap.

Texas added more residents from mid-2018 through mid-2019 than any other state. Marco Bicci/Getty Images

Texas added more residents than any other state in past year

Growing gains

Yes, everything is bigger in Texas — including population growth. From mid-2018 to mid-2019, the Lone Star State added more residents than any other state, new estimates from the U.S. Census Bureau show.

From July 2018 to July 2019, the population of Texas grew by 367,215, according to Census Bureau data released December 30. That's close to the number of people who live in the Dallas-Fort Worth suburb of Arlington (398,112).

Keep in mind that this does not mean nearly 370,000 people moved to Texas in just one year. The Census Bureau's new population estimates represent the number of people who moved to and moved out of each state, as well as the number of births versus deaths.

Texas' 2018-19 population growth eclipsed that of the country's largest state, California.

The Golden State saw its population increase by just 50,635 during the one-year period, the Census Bureau says. What's behind the meager growth? From 2018 to 2019, California's net domestic migration plunged by 203,414. Net domestic migration represents the number of people moving to a state versus the number of people moving out of a state.

Here's another eye opener: Texas accounted for nearly one-fourth of the country's population growth from 2018 to 2019 (1,552,022 people). In that time, 10 states lost population, including Illinois, New Jersey, and New York.

In July 2018, the Texas population stood at an estimated 28,628,666. By July 2019, that figure had climbed to 28,995,881, the Census Bureau says. On a percentage basis, Texas' 2018-19 population growth (1.28 percent) ranked fifth among the states.

Perhaps more impressive is how much Texas expanded from April 2010 (when the last official U.S. headcount was conducted) to July 2019. During that period, Texas added 3,849,790 residents, according to the Census Bureau. To put that into perspective, nearly 4 million people live in the entire state of Oklahoma. Texas' population jumped 15.3 percent from 2010 to 2019, the third highest growth rate behind the District of Columbia and Utah.

Experts cite economic and job growth — along with a low cost of living, a low cost of doing business, and low taxes compared with many other states — as drivers of Texas' population boom. Helping fuel the boom are substantial population spikes in the state's four largest metro areas: Austin, Dallas-Fort Worth, Houston, and San Antonio.

In 2030, the state's population is projected to approach 34.9 million, according to a forecast from the Texas Demographic Center.

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.