Former Shell Chief Scientist Joseph Powell has joined UH to lead its new Energy Transition Institute. Photo via uh.edu

The University of Houston has announced the first leader of its Shell-backed Energy Transition Institute.

Joseph Powell has been named the founding director of the institute, which was founded following a $10 million donation from Shell in spring of last year. Powell is the former chief scientist for Shell and member of the National Academy of Engineering, according to a news release from UH.

“What excites me about my new role is the opportunity to work with students, faculty and industry to make a difference on problems that truly matter," Powell says in the release. "Who could pass that up? Imagine the difficulties that arise when you don’t have access to energy.

“At this point in time, the global transformation to energy abundance is not complete, so we must grow the energy system while reducing its impact on climate and the environment, and also develop circular systems to recycle materials and reduce waste," he continues. "That’s a tall order, but a necessity to bring clean energy and sustainable chemicals into play globally and develop solutions that improve the quality of life for all.”

The appointment was funded by a matching grant from the Governor’s University Research Initiative, a program that was created in 2015 to help Texas's public universities recruit the top researchers. In addition to his role at the institute, Powell will also serve as a faculty member in the Department of Chemical & Biomolecular Engineering at the UH Cullen College of Engineering.

“Dr. Powell brings extensive experience, insight and passion to the position. I anticipate the institute growing under his leadership to further strengthen UH’s position as the Energy University," says Ramanan Krishnamoorti, vice president for energy and innovation at UH, in the release. "We are grateful Governor Abbott prioritizes funding to bring recognized researchers to Texas through GURI and believe Dr. Powell will play a pivotal role in finding solutions to critical local and global challenges around the energy transition."

Powell's name is associated with over 125 patent applications, with more than 60 granted. He has 36 years of chemical engineering experience and has led research and development programs in new chemical processes, biofuels and enhanced oil recovery.

The new institute — through its faculty and industry partnerships — is geared at education and research into the future of affordable and cleaner energy, including hydrogen, carbon management and circular plastics.

“We must be the trusted voice for stakeholders and the community that is objective and knowledgeable, where industry comes to present ideas and challenges, where faculty come with their research interests and expertise to partner and achieve more together, and where students are transformed into the energy workforce and leaders of tomorrow," he says in the release.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.