Put in the effort to create a strong people culture from the start — it can make all the difference for your company. Photo by Tom Werner/Getty Images

Entrepreneurs are driven and tenacious when building a business. However, the laser focus on making a business profitable, from logistics to taxes and everything in between, can sometimes cause one important element to be missed, the people.

The best business plans cannot work without people to implement the details. When a strong people culture is established from the very beginning, the employees who help build the company from the ground up, stay engaged and can become an integral part of the company’s success for years to come.

Below are a few items to help entrepreneurs concentrate on their most precious asset, their people, pinpoint their motivations and learn how employees can enjoy what they do every day, which can take any business to the next level.

Share values

The onus falls on the business leaders within a startup to create a work environment that encourages employees to succeed and enjoy their career. Nurturing a culture rooted in a shared mission and values allows the company to easily build a desirable workplace where employees are eager to return.

When communicating a company’s values, they are more influential when they are lived by leadership. For example, if curiosity is a key value, leadership should encourage teams to ask questions and not be afraid to try to speak up when there may be a more effective path for the business.

It is also important for business owners to look for candidates to fill roles in the growing business who embody their key values. This may mean looking beyond the job description for like-minded people who align with the values and who then bring a positive outlook to the position, are more apt to collaborate and are fully engaged.

Offer unique benefits

Small businesses have the upper hand when it comes to unique benefits because they are a much nimbler organization. When an organization intentionally creates a people-first environment, there is near immediate access to leadership, rapid advancement opportunities are more plentiful and the impact employees at every level can have on the organization is monumental. This is an exciting prospect for so many who share an entrepreneur’s vision.

There are also the traditional benefits that are essential to a strong people culture. This may seem like a daunting prospect, but it can be simple to provide employees, while also competing with large-company benefits, with the help of a professional employer organization. What will strengthen a people culture’s foundation is offering the traditional benefits along with the benefits many enjoyed during the pandemic, which may have been cut by other organizations, such as mental health programs, expanded sick-leave, financial wellness programs, care benefits and others.

When deciding what benefits to offer, it is important to ask employees what benefits mean the most to them. Every benefit may not be feasible, but employees having a say in their benefits further strengthens the people culture.

Communicate

It sounds simple but establishing a culture with transparent communication, within reason, is conducive to a strong people culture. However, for many entrepreneurs, communicating without a plan often leads to not communicating at all.

Set the stage for clear, consistent communication from the very beginning. For example, establishing a standing meeting, whether it is once per week or every morning, allows leadership to share updates, make announcements and point out team wins. For employees, it is an open forum to ask questions. Also setting the standard to talk to employees before making any major policy changes builds trust in the organization, even if the policy change may not be the most desirable for everyone. By surveying staff before a policy change, leadership can clearly communicate the reasoning and have a fully prepared team before implementation.

In a growing business, it is easy to put your head down and grind forward, but engaged employees are essential to making an entrepreneur’s dream come to fruition. Putting in the effort to create a strong people culture from the start will help ensure you have employees who want to be a part of the organization and contribute to its success.

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Jill Chapman is a director of early talent programs with Insperity, a leading provider of human resources and business performance solutions.
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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.