The five finalists in the Top Founder Under 40 category for the inaugural InnovationMap Awards share the challenges they have had to overcome. Photos courtesy

It's not easy being the youngest person in a room, and that's certainly the case for startup founders looking to make an impact on an industry that's been doing things a certain way since before they were born.

The five finalists of the Top Founder Under 40 category for the InnovationMap Awards presented by Techwave were asked to share their challenges overcame as young founders. Here's what they had to say. Click here to register for the livestream.

"It wasn't until I stood my ground by being persistent, and by not being afraid to hand their responsibilities to someone else, that they finally took me seriously."

Photo courtesy of CaseCTRL

— Pamela Singh of CaseCTRL says. "While working as on a Department of Defense Contract, I was leading a development effort with other older white men who were mostly retired military," she explains."They did not appreciate a young ethnic female giving them orders, and would often ignore my email requests or assigned tasks. At first, I felt defeated, but then I had to remember that although they have a lot of knowledge in general, I was the one with the right knowledge for this specific project."

"Changing the minds of experienced executives, who have worked in the energy industry for decades, was an uphill battle that took time and a considerable amount of effort."

With fresh funds, this Houston entrepreneur plans to scale his industrial e-commerce startup

Photo by Colt Melrose for GoExpedi

— Tim Neal of GoExpedi. "Over the years, I have enjoyed great success in my professional career, but that has not come without a few challenges," Neal says. "I am incredibly grateful for my mentors who believed in my vision despite my age."

"I think my go getter attitude has always helped me out and aid me mature faster."

Photo courtesy of LAMIK Beauty

— Kim Roxie of LAMIK Beauty. "Since I started at such young age at 21, after being labeled 'at risk' in high school, I think I have always been seen as 'too young,'" she says. "However, My life motto is 'qualify yourself!'"

"Once I started just being myself and not carrying the weight of the no's it really improved my productivity, my leadership, and my overall success as a person and as a leader in my business."

Emily Cisek, CEO and co-founder of The Postage

Photo courtesy of The Postage

— Emily Cisek of The Postage. "I think advocating for myself and my business as a younger female founder has been a challenge mostly because as a person you want to please the people around you, investors, whoever, and sometimes no matter what you do, they aren't going to be on the same page and that's OK," she says. "But not carrying that forward is what's important. There's been times I've been told no, when I was trying to be exactly what I thought an investor or business partner wanted to hear."

"Typically, companies that have been around and have older leadership can have an advantage."

Photo via TMC.edu

— Emma Fauss of Medical Informatics Corp. She says she's experienced age discrimination early on within the health care industry.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.