Here's what it's like using new connection-focused app that just launched in Houston

Branching out

Timeleft, which specializes in real-life social experiences, has launched in Houston. Here's how it went for CultureMap Austin's editor, Brianna Caleri. Photo courtesy

Editor's note: CultureMap Austin editor Brianna Caleri recently attended a dinner arranged by Timeleft, an app that helps people meet each other. The app just launched in Houston — read about Brianna's experience using the app below.

Conventional wisdom — if I may be so bold as to define it — would suggest that people who want to make friends should: select a genuine interest, join a group centered around it, and keep attending meetings. I have not quite been sold on the generic women's group meetups I see on Facebook; and even the most passionate conversations about my ramen bar neighbor's favorite noodle dishes at have never led us to hang out a second time.

I tend to look for friends who will suggest ethical shopping alternatives, make impassioned, over-intellectualized art recommendations, and stay up late workshopping existential dread. But I recognize that's a lot to ask after one dinner.

Thus, I was both surprised and not surprised at all to really enjoy Austin's second-ever Timeleft dinner, a lightly match-made night out for strangers. I don't think I've discovered a new portal to jump into and skip all the awkward early stages of making adult friends, but I had an energizing night with people who impressed me with their social ease and willingness.

The setup
When someone signs up for the French app Timeleft, they are greeted with a pleasantly detailed, yet broad personality test. First, a this-or-that rapid fire: things like, "Do you consider yourself more of a smart person or funny person?" (Smart.) "Would you rather listen to rock or rap?" (Rock.) "Are your opinions usually guided by logic and facts, or emotions and feelings?" (Tough, but I chose logic.) Next is a 1-10 rating scale in areas like intro/extroversion, stress, spirituality, loneliness, creativity, and habits.

Some of these, like "I enjoy going out with friends" and "How important is family to you?", felt neat and inspired concise answers. Others, like "I enjoy politically incorrect humor" and "I enjoy discussing politics/news," felt like minefields. I do enjoy a wicked joke, but are we talking politically incorrect like The Office, or politically incorrect like I got kicked out of my bookclub and believe no one can take a joke anymore? I selected 3 for political incorrectness, and 8 for discussing news and politics, angling hard toward sensitivity and away from potential, if unlikely belligerence.

According to Timeleft, its algorithm considers these answers and a few other logistics to pair users with a restaurant and with each other, resulting in two medium-size tables at each. Our group of seven met at 68 Degrees Kitchen in East Austin; It would have been eight, but one didn't show up. A Timeleft representative says the app overbooked from the intended five, expecting that some people would not show.

Quoted from Timeleft's algorithm explanation, it focuses on these "main ingredients":

  • "Language: Select yours for fluid dialogue[...]"
  • "Balance: A balanced mix of men and women. Note that Timeleft is favored by women, who often make up over 60 percent of participants (thus 4 per table). [Note: Although Timeleft only mentions men and women on this list, it also offered a nonbinary gender marker)"
  • "Temperament: A mix of introverts and extroverts for a balanced rhythm."
  • "Generation: An age gap of five to seven years for common life echoes."

Before we met, we got to see a basic rundown of who would be joining, detailing profession, nationality, and zodiac signs. (Not my ideal trifecta, considering that six-sevenths of us were American, and I'm fairly confident in my ability to interact with people born on any day.) I don't think it's incredibly open-minded of me, but I did feel slightly nervous that half the group worked in tech; I like tech workers, but can't say I really relate.

The dinner
An unexpected point of beauty in the often overwrought world of app-coordinated socializing: Beyond matching us and making our reservation, Timeleft left us to a normal dinner. We ordered from the regular menu, sat among the regular clientele, and handled the payment ourselves, opting to get in a group chat and Venmo one person for one clean bill. It offered a "game," which was really just a list of conversation topics; We only got through two before the topic changing ran cheerfully rampant.

A group of seven — although it did increase the likelihood that we would all like at least one of our companions — was perhaps a bit too large to get to know anyone especially well. We talked as a large group about as much as we split into side conversations. That was perfectly doable, but it made me wish a few times that we had a quiet table of three or four, where we didn't have to raise our voices past each other or inelegantly shift our attention from one conversation to the next.

We discovered a fair amount in common: places lived, schools attended, foods loved, places traveled, parties and underground scenes frequented. Although some of it dipped very lightly into taboos (Who has been to sex clubs? Who has been kicked out of restaurants?), most of these were surface-level parallels.

I learned that one of my dinner mates shared my lack of enthusiasm for school spirit as a concept, but couldn't say whether it was simply noncommittal or deep-rooted antiestablishmentarianism. I learned that at least one of my dinner mates likes to do yoga, but I don't know if they prefer to work up a sweat to EDM or study the Yoga Sutras.

It would be hard to suss out many of the deeper values behind these things, since seven people sitting at a dinner table together are generally trying to be agreeable — or at least entertaining. We're playing to the lowest common denominator, and we don't really know what our denominators are. We never found the gold thread running through — for instance, if we all rated our passion for working out similarly. But if we could narrow it down that much, it might be time to cut out the middle man and join a CrossFit gym.

The after-dinner drinks, and social patterns
After the small group dinners, all the diners from the various Timeleft tables in South and Central Austin were invited to meet up at Hold Out Brewing. Our group (less one person with a morning appointment) decided to head over. It was already 9:45 pm by the time we left the restaurant, having spent nearly 3 hours together already. We were surprised to see the dense crowd that gathered among the picnic tables.

In reporter mode, I started popping by different groups to find out how their night had gone. I talked to more than a dozen people, all of whom had entirely positive feedback about their evenings. The only criticism I heard was that one person felt the $16 "ticket" to the dinner (which was then priced à la carte) was a bit pricy.

Other groups went to Fresa's Chicken al Carbon, North Italia, and what I have to assume was QI Austin: Modern Asian Kitchen, although diners kept pronouncing it "key." Most groups had met members of the other table at the same restaurant, and some even wandered over during the dinner to see how the other half lived. Our group never found its counterpart.

It seemed to me that our group was objectively the most outgoing. Not only were we the last to arrive after our long dinner (as far as I noticed), but we were also (definitely) the last to leave the brewery. One duo from another group said theirs was a little awkward, in a pleasant way, so the two of them kept up most of the talking. One group said conversation flowed fairly easily, but when there was a lull, they returned to the provided conversation topics. It seemed about equally common to share meals or order for yourself, but our gang all shared everything.

Every group noticed their close ages beyond any other unifying factor. No one offered up any common threads, yet people responded in conversation as if they knew each other, with affectionate interjections like, "Of course he would say that!"

Brianna's gang at the Timeleft dinner in Austin. Photo by Brianna Caleri

Final impression
Most interesting to me was that nearly every single person I talked to all night, including in our own group, first heard about the dinner series on Instagram and just thought it sounded worth trying. Only one person specifically told me that they wanted to make new friends because theirs were mostly from work.

My biggest prejudice before the dinner was that the majority of attendees would either be new to Austin or in need of some outside help in making friends. I was right about the first thing; It seemed like most people had only been here a year or less.

But I was wrong about the second thing. In retrospect, it makes sense that a huge group of people who got together just to get together are deeply friendly. And while I still wouldn't expect long-lasting connections to come out of this Friendly People Convention, I can see that's not exactly what most people are aiming for, either.

The app has direct messaging, but I don't feel inclined to use it. Our group is already on an SMS thread, and I got so many new Instagram followers at the after-event that the next morning, I was not even sure who one of them was. We have started rating our compatibility on the app, and indicating who we would be open to seeing at future events, and who we wouldn't.

If I can have a silly dinner with someone who is investing in the world I want to see, I'll happily get silly. I'm sure some of the people I met yesterday are doing that, but I would have little way of knowing — or at least, a much harder time than if we had started on shared ground.

It's tempting, then, to see this as a way to meet people who are very different from you and expand your worldview. I do think it holds some promise for people who want to legitimately invest in becoming friends with each other and learning what's underneath the amiable surface, but I'm curious about where that sense of initiative will come from. Perhaps more regular dinners hold the answer.

I would be happy to see anyone I met yesterday again, if we end up in the same place at the same time. But I think my days of connecting with strangers over no common objective at all are limited.

----

More information about Timeleft is available at timeleft.com, and the app is available via Apple's App Store and Google Play. Houston's next dinner happens Wednesday, June 19. Dinners happen weekly, and RSVPs must be made no later than Tuesday evening.

This article originally ran on CultureMap.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.

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