Timeleft, which specializes in real-life social experiences, has launched in Houston. Here's how it went for CultureMap Austin's editor, Brianna Caleri. Photo courtesy

Editor's note: CultureMap Austin editor Brianna Caleri recently attended a dinner arranged by Timeleft, an app that helps people meet each other. The app just launched in Houston — read about Brianna's experience using the app below.

Conventional wisdom — if I may be so bold as to define it — would suggest that people who want to make friends should: select a genuine interest, join a group centered around it, and keep attending meetings. I have not quite been sold on the generic women's group meetups I see on Facebook; and even the most passionate conversations about my ramen bar neighbor's favorite noodle dishes at have never led us to hang out a second time.

I tend to look for friends who will suggest ethical shopping alternatives, make impassioned, over-intellectualized art recommendations, and stay up late workshopping existential dread. But I recognize that's a lot to ask after one dinner.

Thus, I was both surprised and not surprised at all to really enjoy Austin's second-ever Timeleft dinner, a lightly match-made night out for strangers. I don't think I've discovered a new portal to jump into and skip all the awkward early stages of making adult friends, but I had an energizing night with people who impressed me with their social ease and willingness.

The setup
When someone signs up for the French app Timeleft, they are greeted with a pleasantly detailed, yet broad personality test. First, a this-or-that rapid fire: things like, "Do you consider yourself more of a smart person or funny person?" (Smart.) "Would you rather listen to rock or rap?" (Rock.) "Are your opinions usually guided by logic and facts, or emotions and feelings?" (Tough, but I chose logic.) Next is a 1-10 rating scale in areas like intro/extroversion, stress, spirituality, loneliness, creativity, and habits.

Some of these, like "I enjoy going out with friends" and "How important is family to you?", felt neat and inspired concise answers. Others, like "I enjoy politically incorrect humor" and "I enjoy discussing politics/news," felt like minefields. I do enjoy a wicked joke, but are we talking politically incorrect like The Office, or politically incorrect like I got kicked out of my bookclub and believe no one can take a joke anymore? I selected 3 for political incorrectness, and 8 for discussing news and politics, angling hard toward sensitivity and away from potential, if unlikely belligerence.

According to Timeleft, its algorithm considers these answers and a few other logistics to pair users with a restaurant and with each other, resulting in two medium-size tables at each. Our group of seven met at 68 Degrees Kitchen in East Austin; It would have been eight, but one didn't show up. A Timeleft representative says the app overbooked from the intended five, expecting that some people would not show.

Quoted from Timeleft's algorithm explanation, it focuses on these "main ingredients":

  • "Language: Select yours for fluid dialogue[...]"
  • "Balance: A balanced mix of men and women. Note that Timeleft is favored by women, who often make up over 60 percent of participants (thus 4 per table). [Note: Although Timeleft only mentions men and women on this list, it also offered a nonbinary gender marker)"
  • "Temperament: A mix of introverts and extroverts for a balanced rhythm."
  • "Generation: An age gap of five to seven years for common life echoes."

Before we met, we got to see a basic rundown of who would be joining, detailing profession, nationality, and zodiac signs. (Not my ideal trifecta, considering that six-sevenths of us were American, and I'm fairly confident in my ability to interact with people born on any day.) I don't think it's incredibly open-minded of me, but I did feel slightly nervous that half the group worked in tech; I like tech workers, but can't say I really relate.

The dinner
An unexpected point of beauty in the often overwrought world of app-coordinated socializing: Beyond matching us and making our reservation, Timeleft left us to a normal dinner. We ordered from the regular menu, sat among the regular clientele, and handled the payment ourselves, opting to get in a group chat and Venmo one person for one clean bill. It offered a "game," which was really just a list of conversation topics; We only got through two before the topic changing ran cheerfully rampant.

A group of seven — although it did increase the likelihood that we would all like at least one of our companions — was perhaps a bit too large to get to know anyone especially well. We talked as a large group about as much as we split into side conversations. That was perfectly doable, but it made me wish a few times that we had a quiet table of three or four, where we didn't have to raise our voices past each other or inelegantly shift our attention from one conversation to the next.

We discovered a fair amount in common: places lived, schools attended, foods loved, places traveled, parties and underground scenes frequented. Although some of it dipped very lightly into taboos (Who has been to sex clubs? Who has been kicked out of restaurants?), most of these were surface-level parallels.

I learned that one of my dinner mates shared my lack of enthusiasm for school spirit as a concept, but couldn't say whether it was simply noncommittal or deep-rooted antiestablishmentarianism. I learned that at least one of my dinner mates likes to do yoga, but I don't know if they prefer to work up a sweat to EDM or study the Yoga Sutras.

It would be hard to suss out many of the deeper values behind these things, since seven people sitting at a dinner table together are generally trying to be agreeable — or at least entertaining. We're playing to the lowest common denominator, and we don't really know what our denominators are. We never found the gold thread running through — for instance, if we all rated our passion for working out similarly. But if we could narrow it down that much, it might be time to cut out the middle man and join a CrossFit gym.

The after-dinner drinks, and social patterns
After the small group dinners, all the diners from the various Timeleft tables in South and Central Austin were invited to meet up at Hold Out Brewing. Our group (less one person with a morning appointment) decided to head over. It was already 9:45 pm by the time we left the restaurant, having spent nearly 3 hours together already. We were surprised to see the dense crowd that gathered among the picnic tables.

In reporter mode, I started popping by different groups to find out how their night had gone. I talked to more than a dozen people, all of whom had entirely positive feedback about their evenings. The only criticism I heard was that one person felt the $16 "ticket" to the dinner (which was then priced à la carte) was a bit pricy.

Other groups went to Fresa's Chicken al Carbon, North Italia, and what I have to assume was QI Austin: Modern Asian Kitchen, although diners kept pronouncing it "key." Most groups had met members of the other table at the same restaurant, and some even wandered over during the dinner to see how the other half lived. Our group never found its counterpart.

It seemed to me that our group was objectively the most outgoing. Not only were we the last to arrive after our long dinner (as far as I noticed), but we were also (definitely) the last to leave the brewery. One duo from another group said theirs was a little awkward, in a pleasant way, so the two of them kept up most of the talking. One group said conversation flowed fairly easily, but when there was a lull, they returned to the provided conversation topics. It seemed about equally common to share meals or order for yourself, but our gang all shared everything.

Every group noticed their close ages beyond any other unifying factor. No one offered up any common threads, yet people responded in conversation as if they knew each other, with affectionate interjections like, "Of course he would say that!"

Brianna's gang at the Timeleft dinner in Austin. Photo by Brianna Caleri

Final impression
Most interesting to me was that nearly every single person I talked to all night, including in our own group, first heard about the dinner series on Instagram and just thought it sounded worth trying. Only one person specifically told me that they wanted to make new friends because theirs were mostly from work.

My biggest prejudice before the dinner was that the majority of attendees would either be new to Austin or in need of some outside help in making friends. I was right about the first thing; It seemed like most people had only been here a year or less.

But I was wrong about the second thing. In retrospect, it makes sense that a huge group of people who got together just to get together are deeply friendly. And while I still wouldn't expect long-lasting connections to come out of this Friendly People Convention, I can see that's not exactly what most people are aiming for, either.

The app has direct messaging, but I don't feel inclined to use it. Our group is already on an SMS thread, and I got so many new Instagram followers at the after-event that the next morning, I was not even sure who one of them was. We have started rating our compatibility on the app, and indicating who we would be open to seeing at future events, and who we wouldn't.

If I can have a silly dinner with someone who is investing in the world I want to see, I'll happily get silly. I'm sure some of the people I met yesterday are doing that, but I would have little way of knowing — or at least, a much harder time than if we had started on shared ground.

It's tempting, then, to see this as a way to meet people who are very different from you and expand your worldview. I do think it holds some promise for people who want to legitimately invest in becoming friends with each other and learning what's underneath the amiable surface, but I'm curious about where that sense of initiative will come from. Perhaps more regular dinners hold the answer.

I would be happy to see anyone I met yesterday again, if we end up in the same place at the same time. But I think my days of connecting with strangers over no common objective at all are limited.

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More information about Timeleft is available at timeleft.com, and the app is available via Apple's App Store and Google Play. Houston's next dinner happens Wednesday, June 19. Dinners happen weekly, and RSVPs must be made no later than Tuesday evening.

This article originally ran on CultureMap.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.