A Texas organization has doled out millions to Houston cancer-fighting professionals

granted

Texas doctors and researchers received millions for their transformational work in cancer prevention and treatment. Getty Images

Researchers at medical institutions across the state have something to celebrate. The Cancer Prevention and Research Institute of Texas has made 71 grants this week to cancer-fighting organizations that total a near $136 million.

"CPRIT's priorities of pediatric cancer research and cancers of significance to Texans highlight this large slate of awards," says Wayne Roberts, CPRIT CEO, in a release. "Investments are made across the cancer research and prevention continuum in Texas unlike any other state in the country."

New to the awards this time around is the Collaborative Action Program for Liver Cancer, which has been claimed by Baylor College of Medicine's Hashem B. El-Serag.

"Texas has the highest incidence rates of hepatocellular cancer in the nation," El-Serag says in a release from BCM. "Our CPRIT funded Center will house infrastructure to support and enhance research collaborations among liver cancer researchers; to educate providers, researchers and the general public on best practices and opportunities to reduce the burden of liver cancer; and to engage private and public entities in policy initiatives."

Houston organizations also received recruitment awards, which reward Texas organizations for bringing in great minds from across the world. According to the release, CPRIT has brought in a total of 181 scholars and 13 companies to the Lone Star State.

Of the 71 grants, 58 represent academic research, 10 prevention, and three product development research. Here are the ones awarded to Houston organizations.

The University of Texas MD Anderson Cancer Center

  • $900,000 granted for Shao-Cung Sun's research in regulation of CD8 T cell responses in antitumor immunity (Individual Investigator Research Award)
  • $897,483 granted for Alemayehu A. Gorfe's research in characterization and optimization of novel allosteric KRAS inhibitors (Individual Investigator Research Award)
  • $3 million granted for Hashem B. El-Serag's research at The Texas Collaborative Center for Hepatocellular Cancer (Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Collaborative Action Center Award)
  • $2.46 million to Jessica Hwang for patient-centered liver cancer prevention in the Houston community (Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Investigator-Initiated Research Awards)
  • $3.51 million for Kevin McBride's Recombinant Antibody Production Core at Science Park
  • $199,804 granted for Andrea Viale's epithelial memory of resolved inflammation as a driver of pancreatic cancer progression (High Impact High Risk Award)
  • $6 million for the recruitment of Christopher Flowers, M.D. (Recruitment of Established Investigator Awards)
  • $2 million for the recruitment of Kevin Nead, MD, MPhil (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
  • $2 million for the recruitment of Alison Taylor, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
  • $2 million for the recruitment of Mackenzie Wehner, MD, MPhil (Recruitment of First-Time, Tenure-Track Faculty Members Awards)

Baylor College of Medicine

  • $5.38 million granted for Steven J. Ludtke's new capabilities for cancer research in the TMC CryoEM Cores (Core Facility Support Awards)
  • $1.35 million granted for Bryan M. Burt's novel endoscope-cleaning port for minimally invasive cancer surgery (Early Translational Research Awards)
  • $199,500 granted for Yohannes T. Ghebre's Topical Esomeprazole for Radiation-induced Dermatitis (High Impact High Risk Award)
  • $199,920 granted for Robin Parihar's targeting of cancer associated fibroblasts with anti-IL-11-secreting CAR T cells (High Impact High Risk Award)
  • $2 million for the recruitment of Umesh Jadhav, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
  • $2 million for the recruitment of Stanley Lee, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
  • $2 million for the recruitment of Ang Li, MD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
  • $1.29 million for Jane R. Montealegre's expansion of "a Community Network for Cancer Prevention to Increase HPV Vaccine Uptake and Tobacco Prevention in a Medically Underserved Pediatric Population"

Texas Medical Center

  • $5.44 million granted for William McKeon's Business-Driven Accelerator for Cancer Therapeutics (Core Facility Support Awards)

The University of Texas Health Science Center at Houston

  • $5.95 million granted for Zhiqiang An's Advanced Cancer Antibody Drug Modalities Core Facility (Core Facility Support Awards)
  • $2 million granted for Qingyun Liu's discovery and development of novel peptibody-drug conjugate for treating cancers of the digestive system (Early Translational Research Awards)
  • $199,998 granted for Leng Han's expression landscape and biomedical significance of transfer RNAs in cancer (High Impact High Risk Award)
  • $2 million for Lara S. Savas' Salud en Mis Manos that delivers "Evidence-Based Breast & Cervical Cancer Prevention Services to Latinas in Underserved Texas South and Gulf Coast Communities"

The University of Texas Medical Branch at Galveston

  • $3.55 million granted for William K. Russell's A Targeted Proteomics and Metabolomics Mass Spectrometry Core Facility at the University of Texas Medical Branch at Galveston (Core Facility Support Awards)
  • $199,996 granted for Brendan Prideaux's novel cellular-level imaging approach to assess payload drug distribution in tumors following administration of targeted drug delivery systems (High Impact High Risk Award)
  • $200,000 granted for Casey W. Wright's targeting ARNT and RBFOX2 alternative splicing as a novel treatment modality in lymphoid malignancies (High Impact High Risk Award)

The Methodist Hospital Research Institute

  • $200,000 granted for Robert Rostomily's development of a mini-pig glioma model and validation of human clinical relevance (High Impact High Risk Award)

Texas Southern University

  • $200,000 for Song Gao's alleviating SN-38-induced late-onset diarrhea by preserving local UGTs in the colon (High Impact High Risk Award)

University of Houston

  • $200,000 granted for Sergey S. Shevkoplyas' Novel High-Throughput Microfluidic Device for Isolating T-cells Directly from Whole Blood to Simplify Manufacturing of Cellular Therapies (High Impact High Risk Award)

Rice University

  • $2 million for the recruitment of Jiaozhi (George) Lu, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
  • $1.67 million for the recruitment of Vicky Yao, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)

The Rose

  • $2 million for Bernice Joseph's Empower Her To Care Expansion

Legacy Community Health Services

  • $999,276 for Charlene Flash's "Increasing Breast and Colorectal Cancer Screening Rates for the Medically Underserved using Population Health Strategies at a Multi-County FQHC"
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Exclusive: Houston Exponential makes strategic marketing hire

innovator to know

Houston Exponential has made another new hire. Clemmie Pierce Martin has joined Houston Exponential as director of marketing and strategy. The nonprofit helps spur the growth of Houston’s innovation ecosystem.

She most recently was director of strategic partnerships and products at Houston-based startup Goodfair, which operates an online thrift store. Before that, she was head of client success at Austin-based startup Mesa Cloud, which offers a platform for tracking student progress.

Martin, who grew up in Houston and graduated from the University of Texas at Austin and Houston’s The Kinkaid School, says her new employer “sees the potential in Houston and our startup ecosystem that I’ve always felt was underserved and underrepresented nationally. I couldn’t be more excited to join a team that is working tirelessly to make sure that for founders and startups anywhere in the world, Houston is not just a choice but rather the clear choice of venue.”

Martin is a great-niece of the late President George H.W. and the late first lady Barbara Bush.

Serafina Lalany, the new executive director of Houston Exponential (HX), says Martin’s experience with startups “is an invaluable asset to the organization.”

“Her insights and experiences … couldn’t be more fitting for HX’s mission to lower the barrier of entry for early stage startups in the city,” Lalany says in a news release.

Lalany became executive director of HX in September. She had been the organization’s vice president of operations and chief of staff. Lalany succeeds Harvin Moore, who resigned this summer as president and CEO of the four-year-old nonprofit.

Earlier this month, HX named Ivery Boston III as director of inclusive innovation. He previously worked for the Miami Downtown Development Authority.

Aside from the new hires, the organization recently restructured its board of directors. The board transitioned to a more informal “convening” board, and an executive committee now oversees HX’s operations.

University of Houston: Navigating between researcher and professor

houston voices

What is the difference between a professor teaching and conducting research? When does a professor need an Institutional Review Board to provide oversight on their project? The NSF has had this come up often enough, presumably, that they wrote a vignette on their website.

Let's take a quiz

The NSF presented the following scenario: “Professor Speakwell teaches undergraduate courses in linguistics in which he demonstrates variability in both the syntax and vocabulary of spoken expression across individuals and cultures. Professor Speakwell involves his students in active learning in the classroom. He brings recordings of spoken English to class and calls on students to say whether they find the example grammatical and to explain or guess what the utterance means.”

Pretty straightforward, right? A professor is a teacher. But most professors move from role-to-role like a chameleon: researcher, artist, CEO, etc. depending on their discipline.

Here's the question

“Professor Researchit, a colleague of Speakwell’s, uses these same techniques with undergraduate student volunteers to do research on variables that predict understanding of utterances. Dr. Researchit develops a protocol, and obtains IRB approval and students’ signed informed consent. Professor Researchit tells Speakwell that he had better get IRB approval and student informed consent since he is doing the same thing.”

Is Professor Researchit Correct?

Danielle Griffin, Ed.D., associate director of the Research Integrity and Oversight Office in the Division of Research at University of Houston was asked to weigh in on this vignette. She answered by saying, “No, Speakwell is not doing the same thing. Speakwell is teaching, not doing research.”

“The keywords in the first paragraph are ‘involves his students in active learning in the classroom.’ Active learning and research are two different things. They are doing hands-on learning about how to conduct research,” she went on to say. “Professor Researchit is actually doing research because the students are participants and the subjects of the data collection.”

Decision tree

When does a professor need an IRB? The government’s Health and Human Services website boasts an Office for Human Research Protections. You can find a “decision tree” there. It helps professors to determine whether an IRB is required for their research. Every institution has something similar; for instance the University of Rhode Island offers a similar tool to figure out the IRB process in a flow chart. The overarching rule is that if you are using human subjects in a clinical trial — you do need IRB oversight.

According to the University of Iowa, “publicly available data do not require IRB review. Examples: census data, labor statistics.” But they also provide a dense, comprehensive list of what else can be conducted without an IRB in place.

The Big Idea

When in doubt of whether you need an IRB or not, reach out to your institution’s IRB facilitators or the office that handles oversight, ethics and integrity. The Research Integrity and Oversight (RIO) Office at the University of Houston, for instance, “supports and educates the research community in all areas of compliance with federal regulations concerning human subjects, animal subjects, conflicts of interest, grant congruency and responsible conduct of research.” It’s better to be safe than sorry, but if the lesson you’re teaching benefits the student, it is probably not a research project.

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This article originally appeared on the University of Houston's The Big Idea. Cory Thaxton, the author of this piece, is the communications coordinator for The Division of Research.

Houston data analytics firm acquired by Austin agency

m&a moves

Statistical Vision, a Houston-based data and analytics firm, has been scooped up by Austin-based marketing and communications agency Hahn Public for an undisclosed amount.

The deal expands Hahn Public to a 48-person agency with combined annual revenue exceeding $10 million. Statistical Vision has been rebranded as Hahn Stats.

“Our clients come to us drowning in data — sales transactions, marketing information, commodity prices, import and export data, demographics, weather forecasts, etcetera,” Michael Griebe, co-founder and chief statistical officer of what now is Hahn Stats, says in a news release. “We build predictive analytic models to answer specific questions and to point our clients towards revenue growth.”

Griebe and Dirk Van Slyke founded Statistical Vision in 2014. The company's local office is at The Cannon West Houston. Hahn Stats LLC also has an office in Denver.

The data and analytics prowess developed by Statistical Vision will benefit Hahn Public clients like Houston-based ZTERS, Whataburger, the Texas Department of Agriculture, Beef-Loving Texans, H-E-B’s Central Market, Vital Farms, the Propane Education & Research Council, OneGas, GPA Midstream, the East Texas Electric Cooperative, and the Northeast Texas Regional Mobility Authority.

Jeff Hahn, principal of Hahn Public, says the acquisition of Statistical Vision and its data and analytics capabilities will help Hahn Public’s array of food and energy clients, who “continue to face a rapidly changing and uncertain landscape.”

Other businesses under the Hahn umbrella are Apron Food & Beverage Communications, Predictive Media Network, and White Lion Interactive.

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