Houston universities climb the ranks on annual list of most patents issued

top 100

UH and Rice University appear on the NAI's Top 100 U.S. Universities Granted Utility Patents. Photo courtesy of University of Houston

The University of Houston and Rice University have claimed spots on the National Academy of Inventor's Top 100 U.S. Universities Granted Utility Patents.

The list is based on data obtained from the U.S. Patent and Trademark Office and ranks U.S. academic institutions that are advancing innovation by the number of utility patents issued in the prior year.

Utility patents are among the world’s most valuable assets because they give inventors exclusive commercial rights to produce and use their technology. The universities ranked on the list collectively hold nearly 6,500 patents.

“In the ever-evolving innovation landscape, it is imperative that the U.S. is remaining competitive and at the forefront of today’s emerging research and technologies,” Paul R. Sanberg, president of the NAI, said in a news release. “Ensuring the security of intellectual property through patenting is a crucial component to this and allows those innovations to be effectively moved to market, where they can create valuable societal and economic impact. The Top 100 U.S. list celebrates U.S. universities and their inventive staff and faculty for their dedication in ensuring their innovations and IP are protected.”

The University of Houston System came in at No. 62 with 34 patents, and Rice University claimed the No. 68 spot with 30 patents.

Both universities climbed up the rankings this year. Last year, UH was ranked No. 63 with 27 patents. Rice climbed an impressive 26 spots this year, after ranking No. 94 with 14 patents issued in 2023.

“Granted U.S. utility patents can tremendously help in commercializing the technologies covered by such patents by attracting industry investment and commercial partners on a global level,” Neha Malik, assistant director for intellectual property management in Rice's Office of Technology Transfer, said in a release. “Advancing in this list memorializes Rice’s commitment to support research programs of Rice faculty by generating a path for the university to bring its research to the marketplace.”

Other Texas universities on the list include:

No. 3 University of Texas System (234 patents)
No. 35 The Texas A&M System (61 patents)
No. 73 Texas Tech University System (25 patents)
No. 80 Baylor University (20 patents)

The University of California (540 patents) claimed the No. 1 spot again this year, followed by the Massachusetts Institute of Technology (295 patents), which also placed second for 2024.

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Houston's Welch Foundation has awarded more than 80 grants to support chemical research and careers in Texas for 2025. Photo via Getty Images

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

David Pruner, executive director of TEX-E, joins the Houston Innovator Podcast. Photo via LinkedIn

This Houston innovator's statewide mission to advance energy transition innovation on college campuses

houston innovators podcast episode 224

Collaboration is the name of the game for David Pruner, executive director of the Texas Entrepreneurship Exchange for Energy, known as TEX-E, a nonprofit housed out of Greentown Labs that was established to support energy transition innovation at Texas universities.

TEX-E launched in 2022 in collaboration with Greentown Labs, MIT’s Martin Trust Center for Entrepreneurship, and five university partners — Rice University, Texas A&M University, Prairie View A&M University, University of Houston, and The University of Texas at Austin.

Pruner was officially named to his role earlier this year, but he's been working behind the scenes for months now getting to know the organization and already expanding its opportunities from students across the state at the five institutions.

"In the end, we have five different family members who need to be coordinated differently," Pruner says on the Houston Innovators Podcast. "There's plenty of bright students at each of these schools, and there's plenty of innovation going on, it's whether it can grow, prosper, and be sustainable."

Pruner describes the organization as pulling the best resources from each of the schools, with TEX-E operating as a bit of a matchmaker to connect students across the state through in-person opportunities and its digital platform.

"Our main job is to look to connect everyone, so that an engineer at Texas A&M that has an idea that they want to pursue, but they don't know the business side, can meet that Rice MBA," Pruner says, giving a hypothetical example. "Then, when they realize it's going to be a highly regulated product, we need a regulatory lawyer at UT — we can make all that happen and connect them."

TEX-E's programming includes a bootcamp course, fellowship opportunities at each school, and an annual startup competition at CERAWeek with $50,000 of pre-seed funding up for grabs. Next year, as Pruner explains on the show, the organization will also roll out an accelerator.

Pruner shares more about the program and its future, as well as his views on Houston as a major leader for the energy transition.

Rice University — sometimes known as the "Ivy League of the South" — has been ranked as the best school in the Lone Star State. Courtesy of Rice University

Rice University tops best schools in Texas list

Top of the class

By any measure, Rice University is a top-tier academic institution, lauded locally and nationally for its innovative tuition programs and for boasting the highest-paid graduates in the state. Now, a new ranking names the "Ivy League of the South" the top university in Texas.

Personal finance website WalletHub has released its 2020's Best College & University Rankings, just in time for the looming November 1 "early decision" college application deadline. Rice takes the No. 1 Texas spot and comes in at No. 13 overall in the U.S.

In order to determine the rankings, WalletHub compared more than 1,000 colleges and universities across seven key dimensions: student selectivity, cost and financing, faculty resources, campus safety, campus experience, educational outcomes, and career outcomes.

Among Texas schools, Rice comes in first for the following individual metrics: admission rate, student-faculty ratio, graduation rate, and post-attendance median salary. The school places second for gender and racial diversity.

The University of Texas at Austin follows as the No. 2 best school in Texas, while Trinity University comes in third. Here are the top 10 schools in Texas, according to WalletHub:

Rice University
University of Texas at Austin
Trinity University
Baylor University
LeTourneau University
Texas Christian University
Texas A&M University-College Station
University of Dallas
Southwestern University
Southern Methodist University

At No. 13 on the overall list, Rice shares the spotlight with prestigious institutions, coming in behind the Massachusetts Institute of Technology, Harvard University, Princeton University, Yale University, Stanford University, the California Institute of Technology, Duke University, University of Pennsylvania, Northwestern University, University of North Carolina — Chapel Hill, Vanderbilt University, and Columbia University. University of Chicago is No. 14.

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This article originally ran on CultureMap.

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5 must-read Houston innovation headlines: AI for seniors, major Meta news

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Editor's note: The first half of June brought big innovation headlines for Houston, from AI exploration to major Meta investments and the 2026 Fortune 500 list. Below are the five most-read InnovationMap stories published June 1-14, 2026:

1. Houston lab explores how AI bots can help the elderly

The University of Houston’s Empathetic Lifespan AI & Robotics for Aging (ELARA) Lab is currently conducting research into how AI bots may be able to help the elderly live more social and independent lives through several ongoing initiatives. The lab officially launched last month as part of the Gerald D. Hines College of Architecture & Design under the leadership of Assistant Professor Chorong Park. Part of the lab’s mission is tackling ongoing problems with aging, such as dealing with disabilities and social isolation. Researchers’ current work is focused on designing a new AI companion bot specifically tailored to the needs of older people. Continue reading.

2. New UH survey reveals concerns over AI data center growth in Houston

A new report out of the University of Houston shows that area residents remain wary of the long-term effects of operating data centers. The recent survey from the University of Houston’s latest SPACE City Panel, conducted by the Center for Public Policy at the Hobby School of Public Affairs, shows that while 85 percent of Houston-area residents use AI, nearly 63 percent oppose the construction of AI data centers within 1 mile of their homes. Continue reading.

3. Meta to bring $115 million AI data center training initiative to Houston

Meta and Associated Builders and Contractors have entered into a partnership to invest $115 million in training programs for the construction of AI data centers, with a portion of the project launching in Houston. The companies announced June 8 that they would open America’s Workforce Academies at ABC chapter training centers in Houston; Indianapolis; Baton Rouge, Louisiana; and Columbus, Ohio. Continue reading.

4. 27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston is a giant among U.S. hubs for corporate headquarters. The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 23 Fortune 500 headquarters. Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3. Continue reading.

5. 7 Houston neighbors named to U.S. News' best places to live in 2026

Several Houston suburbs have been crowned the best places to live in the U.S. for 2026, according to U.S. News & World Report. Sugar Land is the highest-ranked city in the Houston metro, and it ranks as the 10th best place to live in the country. Continue reading.

Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

No. 9 ExxonMobil
No. 21 Chevron
No. 29 Phillips 66
No.55 Sysco
No. 75 ConocoPhillips
No. 89 Enterprise Products Partners
No. 103 Plains GP Holdings
No. 133 Hewlett Packard Enterprise
No. 149 NRG Energy
No. 157 Quanta Services
No. 164 Baker Hughes
No. 173 Occidental Petroleum
No. 179 Waste Management
No. 201 EOG Resources
No. 204 Group 1 Automotive
No. 207 Halliburton
No. 223 Cheniere Energy
No. 236 Corebridge Financial
No. 262 Targa Resources
No. 266 Kinder Morgan
No. 388 Westlake
No. 435 CenterPoint Energy
No. 438 APA
No. 440 Comfort Systems USA
No. 455 NOV
No. 488 KBR
No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.

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