U.S. Transportation Secretary Elaine Chao used SXSW to make the announcement. Photo courtesy of Hyperloop One

Creation of a transportation-in-a-tube system that promises to whisk passengers from Houston to Dallas in 30 minutes got a big boost March 12 from the federal government.

During an appearance at SXSW, U.S. Transportation Secretary Elaine Chao said she has established a transportation technology council that will aim to clear regulatory and legal roadblocks for the traffic-busting Virgin Hyperloop One concept and similar transit innovations.

In September 2017, the company behind Hyperloop One picked a 640-mile route in Texas for the initiative. The futuristic system — with passengers riding in pods carried through a massive tube — would connect Houston, Austin, Dallas-Fort Worth, Laredo, and San Antonio. Hyperloop One would provide two stops each in the Dallas-Fort Worth and Houston areas, and one each in Austin, Laredo, and San Antonio.

The north-south leg of Hyperloop One would run between Dallas-Fort Worth and Laredo, while the east-west leg would operate between Houston and San Antonio. As imagined now, a trip between Austin and Dallas would last 19 minutes at speeds up to 670 mph — two to three times faster than high-speed rail and 10 to 15 times faster than traditional rail. A ride from Houston to Austin would take 21 minutes, while a trek from Houston to San Antonio would last 26 minutes.

"Texas is exploring how to make hyperloop a reality at the state and local level, but federal support is a huge key for us to be certified and successful," Ryan Kelly, head of marketing and communications for Virgin Hyperloop One, tells CultureMap. "It is exciting that the federal government is recognizing us as a potential new mode of transportation that can be a leap forward for America. Hopefully, Texas can be a first mover."

Aside from Texas, Virgin Hyperloop One has U.S. projects underway in Colorado, Missouri, and the Chicago-Columbus-Pittsburgh corridor. Virgin Group, led by Sir Richard Branson, is among the investors in Hyperloop One.

The federal council unveiled at SXSW will help fast-track a first-of-its-kind transportation network in the U.S. that shares components with trains, planes, and self-driving vehicles. Members of the council will explore technological innovations, such as transit tunnels and self-driving vehicles, in the quest to speed up development of Virgin Hyperloop One and other emerging modes of mass transportation.

"Hyperloop is a new mode of transportation that is built for the 21st century," Jay Walder, CEO of Virgin Hyperloop One, says in a release. "We want to be the company that spearheads the next giant leap forward in transportation here in the United States, but we know we can't do it alone."

Kelly says it's unclear when Texas passengers might be able to travel on Virgin Hyperloop One's network, but the company hopes the first route — wherever it may be — will be ready by the end of 2028.

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This story originally ran on CultureMap.

ElecTrip uses eco-friendly Teslas to shuttle business people to and fro across the state. Courtesy of Electrip

Texas startup using Tesla cars for more efficient and eco-friendly travel

Rethinking roadtrips

A Texas startup shuffling business men and women across the state in style has created an elevated road trip experience for its customers.

Founded in 2018 and based in Austin, ElecTrip aims to add luxury and convenience to regional commutes between major Texas cities by providing transportation in Teslas equipped with WiFi, complimentary snacks, and professional drivers.

Mandeep Patel, a University of Texas at Austin student, had the idea for the company just about a year ago while completing an internship. Patel had the company up and running just a few months later.

Patel serves as founder and CEO, along with his classmate and co-founder, Eliott Lee, who is COO. Lee tells InnovationMap that he and Patel had gotten tired of the stress of airport travel, the restrictive schedule of buses, and the soul-draining fatigue of driving. ElecTrip's no-compromise solution is cost effective, comfortable, and carbon neutral.

"One thing we really pride ourselves on is being sustainable, energy-efficient, and having no emissions," Lee says.

ElecTrip offers door-to-door service for their customers, who can customize pickup and drop-off locations in any major Texas city. The company has eight routes between Houston, Austin, Dallas, and San Antonio, but customers can book a custom route within a 300-mile radius of those cities. Prices range from $249.99 to $429.99, but customers can opt to share rides to cut down on cost, with cars seating three to five riders.

"We emphasize on B2B, geared more towards businesses," says Lee, explaining that customers can customize their trip with food and beverage requests.

The company offers three different Tesla models: Tesla Model S, Tesla Model X, and Tesla Model 3, each offering a specific number of passenger seats, luggage capacity, and mileage range.

"The main reason why we chose Tesla is because of the supercharger network," says Lee in referring to Tesla's 1,422 Supercharger Stations throughout the United States.

Clients don't have to worry about the charging process, Lee says. The company plans the trips around these charging stations, which are free to any Tesla user.

ElecTrip is less than a year old and has already coordinated hundreds of rides, according to the website. While starting the company while still juggling classes — Lee expects to graduate from UT in 2020, while Patel is graduating this year — Lee says being a student-run startup has its perks.

"We find a lot of funding in startup competitions that only students have access to," said Lee.

Additional initial funding for the company came out of Patel's savings account, Lee says. ElecTrip owns one Tesla and rents out additional vehicles to cover the demand of rides. Lee explains that renting vehicles instead of owning them would cut back on the company's real estate while providing additional income for Tesla owners that aren't using their cars.

Patel and Lee are the only two full-time employees at ElecTrip, as all drivers work on a contract-basis. Lee tells InnovationMap that in the future, ElecTrip will focus on business partnerships.

"A lot of these other services are geared towards consumers," says Lee. "We hope to be geared toward mainly towards businesses in the long run."

ElecTrip is gearing up for growing its partnerships with local small businesses in Austin and Houston to provide food and drink products for rides.

"It is something we're looking at targeting in the next one or two months," says Lee.

Mandeep Patel (left) and Eliott Lee are the co-founders of ElecTrip, a travel company that uses Teslas across Texas.Courtesy of ElecTrip

Virgin Trains may be speeding into Texas. Photo courtesy of Virgin Trains

Transportation company steers talk of high-speed trains between Houston, Austin, and San Antonio

ALL ABOARD?

You've likely heard of the proposed high-speed "bullet" train that would connect Houston and Dallas, as well as the proposed transportation-in-a-tube concept that would link Houston, Austin, Dallas, San Antonio, and Laredo.

Now, another possible alternative to planes, Amtrak trains, and automobiles has chugged into the picture.

Virgin Trains USA, a transportation startup that plans to trade its shares on the Nasdaq stock exchange, is exploring two high-speed routes in Texas — one tying together Houston, Austin, and San Antonio, and the other between Houston and Dallas. All four of those cities are plagued by ever-increasing traffic tie-ups.

There's no word yet on when these routes might take shape. At this point, they're merely ideas, and ahead of the company going public, officials at Virgin Trains are staying mum.

In all, Virgin Trains has outlined seven potential routes in the U.S. beyond what it already has on the drawing board.

"Our goal is to build railroad systems in North America that connect major metropolitan areas with significant traffic and congestion," the company says in a filing with the U.S. Securities and Exchange Commission.

Virgin Trains aims to tie together heavily populated cities separated by 200- to 300-mile distances that are "too long to drive, too short to fly." It wants to run the trains along existing transportation corridors — rail, highway or a combination of the two — "to cost-effectively build our systems, as opposed to developing entirely new corridors at potentially significantly higher costs."

If the Virgin name sounds familiar, it should. British billionaire Sir Richard Branson's Virgin Group is a minority investor in Virgin Trains, which already operates a South Florida route between Miami and West Palm Beach. West Palm Beach-to-Orlando and Orlando-to-Tampa routes also are in the works in Florida, in addition to a Los Angeles-to-Las Vegas route. Virgin's other transportation investments include airlines and space travel.

Jim Mathews, president and CEO of the Rail Passengers Association, says he's on board with the Branson-backed Virgin Trains venture — not as an "anti-Amtrak" move but as an advancement in U.S. passenger rail travel.

"Speaking from the experience of someone who spent almost his entire career watching Sir Richard innovate, invest, and take risks, I firmly believe this could be a real shot in the arm for passenger rail in the United States," Mathews writes on the association's website. "Like all entrepreneurs, Sir Richard isn't afraid to fail, and he has made a few bad bets in the past. But he's also made some very good ones, and has transformed not just travel but philosophies wherever he has gone."

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This story originally ran on CultureMap.

TxDOT has a new task force focused on keeping Texans informed on self-driving vehicles that are getting road ready. Getty Images

Texas forms task force geared at autonomous vehicle development

Road to unmanned driving

Self-driving cars are en route to Texas, and the state government wants to ensure Texas is ready for the ride. The Texas Department of Transportation announced the creation of a Connected and Autonomous Vehicle Task Force on Jan. 24.

The CAV Task Force will focus on being a comprehensive resource for information on all Texas CAV projects, investments, and initiatives, the press release says. The organization will also host events surrounding CAV progress and education around the topic.

"With our world-class universities, top-notch workforce and startup culture, Texas is a national leader in the development of new technologies," says Gov. Greg Abbott in the release. "As transportation technology advances, the CAV Task Force will ensure that the Lone Star State remains at the forefront of innovation."

TxDOT's interest, the release reports, is in hopes that the self-driving technology will minimize accidents and maximize safety, as well as expand opportunities for residents, especially within the elderly and disabled populations who currently don't have reliable transportation to their errands and appointments.

In 2017, in the 85th Texas Legislative Session, Abbot signed Senate Bill 2205 into law. The legislation identifies key requirements for CAVs, such as insurance and adhering to traffic laws, like normal vehicles, as well as requiring video recording devices in the car, the Texas Tribune reported. However, it's worth nothing that self-driving vehicles were already being experimented with in Austin by the likes of Google, the Tribune notes.

"Our goal is to further build on the momentum already established with the Texas Technology Task Force and the Texas Innovation Alliance, and work with interested parties on the latest and greatest in CAV projects and enhancements," says TxDOT Executive Director James Bass. "We look forward to furthering these important efforts as connected and autonomous vehicles become reality."

TxDOT is also focusing on rail planning, as the Houston-Dallas high-speed rail chugs along. Earlier this month, the state asked for Texans' feedback on the projects.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."