The show must go on with these SXSW-related events in Houston and Austin

Texas strong

SXSW was canceled this year due to the rising threat of COVID19, aka the coronavirus, but these events are still ones to check out if you are still planning on attending. Marie Ketring/via sxsw.org

With SXSW canceled — and now the Houston Livestock Show and Rodeo has followed suit — and Austin and Houston entrepreneurs are reeling from the loss of networking, pitch competitions, and business opportunities. But unaffiliated organizations are trying to keep some of the spirit of SXSW alive in both Texas cities and online.

"Coronavirus dropped an economic bomb on Austin, and we are trying to triage the scraps," says Marc Nathan, vice president of client strategy at Egan Nelson, an Austin-based, startup-focused law firm.

The economic impact of SXSW 2019 was reported by the organization to have been over $350 million, and, even assuming this year's festival was on par with that, the city of Austin has lost more than that — from the affect on restaurants, lodging, and more. At this point, refunds are not being given out to badge holders.

Additionally, the organization itself is hurting. The 10-day festival has a year-round staff of over 150 people, and SXSW has recently laid off around 30 percent of those employees. Nathan, who says he highly suspects the organization will have to look into restructuring or even bankruptcy, also notes the cancelation will hurt individuals in a way that's not so easy to track.

"This did affect individuals," Nathan says. "Yes, the big brands were hurt and lost a lot of money, but it's not about them. It's about the little guys — the startups that wanted to launch, the bands that wanted to play, or the films that were selected for the contest. It's all the people who use SXSW as a platform, and that platform just disintegrated."

A group of scrappy Austinites have banded together to create Rally Austin and are putting together resources and events online for those still coming into the city and are looking to network responsibly. A few events are also taking place digitally. Here's a list of events to attend, and keep an eye on Rally Austin for any last-minute updates.

Houston-based WatchHerWork's Female Founders Day (March 12 in Austin)

Two Houston female founders — Reda Hicks and Denise Hamilton — saw an opportunity to make SXSW more female friendly, and that's what they've done by introducing this new unofficial SXSW event. Click here for more.

Hicks recently joined the Houston Innovators Podcast to discuss the opportunity. Click here to listen.

SoFin @ SXSW 2020 (March 13 in Austin)

Focused on fintech solutions, SoFin will go on as planned and will feature Houston-based iownit.us, a blockchain-enabled investment platform. Click here for more info.

The Austin Tech Happy Hour will also still be held on Friday, March 13, in Austin. Click here for more info.

Houston-based Hatch Pitch Competition (March 16 hosted online)

The annual pitch competition, which is usually streamed online, will switch to completely online only. Click here for more info.

Hatch Pitch is also expected to host a Houston-based, cybersecurity-focused competition next month. Click here to read more.

OpenCoffee Club (March 16 in Austin)

Open Coffee Club, a monthly networking opportunity, will continue as planned. Networking is encouraged, handshaking is not. Click here for more info.

Digital Pitch - An Alternative to SXSW2020 (March 17 hosted online)

Houston's Startup Grind has organized a digital pitch competition that will be hosted completely online. Click here for more info.

Startup of the Year Virtual Pitch Competition (March 17 hosted online)

The Established's annual pitch competition is going online, despite The Established House's physical location being canceled. A Houston-based company will still pitch and the competition has Houston judges involved as well. Click here for more info.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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