A group of Houstonians have launched a virtual tutoring platform for students in Kindergarten through eighth grade. Image via teachingtogive.org

Seven local high schoolers took lessons from their own schooling challenges in 2020 to launch a free, virtual tutoring program last month with the goal of helping younger students close learning gaps of their own during this unprecedented academic year ahead.

Dubbed Teaching To Give, the project matches kindergarten through eighth grade students with honor roll high schoolers from Kinder High School for the Performing and Visual Arts, Strake Jesuit, and Bellaire High School for 30- to 45-minute teaching sessions in core subjects, languages, debate, and arts via Zoom.

Kinder HSPVA sophomore Weillison Hsu, who now serves as president of Teaching to Give, first proposed the idea to fellow piano major and Vice President Hayden Miller at the end of the 2019-20 school year. The 15-year-olds are bright, talented, and artistic, but their freshman years had not come without challenges: First, several of their teachers were required to take a leave of absence, leaving them with long-term substitutes. Then COVID-19 hit, making traditional learning impossible.

It took time to adjust, Miller says, but eventually he and his peers found their stride in the tech-based schooling style that Houston Independent School District has been following for months. Still, they feared the transition for younger students had not been as smooth.

"We have been used to that independence, where in elementary school, and middle school even, you do a lot hands on and in person," Miller says. So, they decided to help in a way that was safe, affordable, and approachable.

"During these times, it's just not possible to make sure that everyone is fully striving," Miller says. "We wanted to make it as easy as possible for parents to use us and to have a stress-free environment, to provide a successful education and set up."

Today, Teaching to Give has held more than 100 free web-based tutoring sessions for kids around the city in subjects from science to piano. They ask on-boarding students to complete a personality and learning style questionnaire and place them with one of their 29 tutors who they predict will work best with for their subject matter and interests. Miller says the minor age difference has allowed their sessions to have real impact.

"It provides a more relatable experience," he says. "A lot of the time we'll have the same interests as our students. We can use that to foster mutual excitement for the subject material."

Still, the group is learning how to teach in a virtual setting as they go.

"It really forces you to think of how you say things to get the result that you want," Miller says. "I think we will all come out of this as better communicators."

Miller, Hsu, and the five other board members — Lina Wu, Amy Park, Fiona Condron, Rushil Chetty, and Ashley Chu — plan to continue to focus on virtual tutoring sessions even after the pandemic ends and limitations on in-person learning lift. Again pulling from their own experience, they know that virtual options can provide big benefits for busy parents and students like themselves.

And in the meantime, they're hoping to start partnerships with a few local lower schools, are accepting applications for additional tutors, and are raising awareness for their new initiative, Project Pencil, which will donate art supplies to the Gregory-Lincoln Education Center in the Fourth Ward.

"Art is something that is universal. It takes away the stress of learning. Also, art lessons and music lessons are very expensive," Miller adds. "We wanted to incorporate that into our classes because that's what our biggest strengths lie in. We wanted to share that passion and provide a way to spread more unity between people. Art has a way of doing that."

Teaching to Give founders (Weillison, Hayden and Lina) virtually meeting with Thomas Porter, HISD Magnet Coordinator for Gregory Lincoln. Image courtesy of Teaching to Give

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CultureMap Emails are Awesome

Houston investor on SaaS investing and cracking product-market fit

Houston innovators podcast episode 230

Aziz Gilani's career in tech dates back to when he'd ride his bike from Clear Lake High School to a local tech organization that was digitizing manuals from mission control. After years working on every side of the equation of software technology, he's in the driver's seat at a local venture capital firm deploying funding into innovative software businesses.

As managing director at Mercury, the firm he's been at since 2008, Gilani looks for promising startups within the software-as-a-service space — everything from cloud computing and data science and beyond.

"Once a year at Mercury, we sit down with our partners and talk about the next investment cycle and the focuses we have for what makes companies stand out," Gilani says on the Houston Innovators Podcast. "The current software investment cycle is very focused on companies that have truly achieved product-market fit and are showing large customer adoption."

An example of this type of company is Houston-based RepeatMD, which raised a $50 million series A round last November. Mercury's Fund V, which closed at an oversubscribed $160 million, contributed to RepeatMD's round.

"While looking at that investment, it really made me re-calibrate a lot of my thoughts in terms what product-market fit meant," Gilani says. "At RepeatMD, we had customers that were so eager for the service that they were literally buying into products while we were still making them."

Gilani says he's focused on finding more of these high-growth companies to add to Mercury's portfolio amidst what, admittedly, has been a tough time for venture capital. But 2024 has been looking better for those fundraising.

"We've some potential for improvement," Gilani says. "But overall, the environment is constrained, interest rates haven't budged, and we've seen some potential for IPO activity."

Gilani shares more insight into his investment thesis, what areas of tech he's been focused on recently, and how Houston has developed as an ecosystem on the podcast.

Houston startup scores $12M grant to support clinical evaluation of cancer-fighting drug

fresh funding

Allterum Therapeutics, a Houston biopharmaceutical company, has been awarded a $12 million product development grant from the Cancer Prevention and Research Institute of Texas (CPRIT).

The funds will support the clinical evaluation of a therapeutic antibody that targets acute lymphoblastic leukemia (ALL), one of the most common childhood cancers.

However, CEO and President Atul Varadhachary, who's also the managing director of Fannin Innovation, tells InnovationMap, “Our mission has grown much beyond ALL.”

The antibody, called 4A10, was invented by Scott Durum PhD and his team at the National Cancer Institute (NCI). Licensed exclusively by Allterum, a company launched by Fannin, 4A10 is a novel immunotherapy that utilizes a patient’s own immune system to locate and kill cancer cells.

Varadhachary explained that while about 80 percent of patients afflicted with ALL have the B-cell version, the other 20 percent suffer from T-cell ALL.

“Because the TLL population is so small, there are really no approved, effective drugs for it. The last drug that was approved was 18 or 19 years ago,” the CEO-scientist said. 4A10 addresses this unmet need, but also goes beyond it.

Because 4A10 targets CD127, also known as the interleukin-7 receptor, it could be useful in the treatment of myriad cancers. In fact, the receptor is expressed not just in hematological cancers like ALL, but also solid tumors like breast, lung, and colorectal cancers. There’s also “robust data,” according to Varadhachary for the antibody’s success against B-cell ALL, as well as many other cancers.

“Now what we're doing in parallel with doing the development for ALL is that we're continuing to do additional preclinical work in these other indications, and then at some point, we will raise a series A financing that will allow us to expand markets into things which are much more commercially attractive,” Varadhachary explains.

Why did they go for the less commercially viable application first? As Varadhachary put it, “The Fannin model is to allow us to go after areas which are major unmet medical needs, even if they are not necessarily as attractive on a commercial basis.”

But betting on a less common malady could have a bigger payoff than the Allterum team originally expected.

Before the new CPRIT grant, Allterum’s funding included a previous seed grant from CPRIT of $3 million. Other funds included an SBIR grant from NCI, as well as another NCI program called NExT, which deals specifically with experimental therapies.

“To get an antibody from research into clinical testing takes about $10 million,” Varadhachary says. “It's an expensive proposition.”

With this, and other nontraditional financing, the company was able to take what Varadhachary called “a huge unmet medical need but a really tiny commercial market” and potentially help combat a raft of other childhood cancers.

“That's our vision. It's not economically hugely attractive, but we think it's important,” says Varadhachary.

Atul Varadhachary is the managing director of Fannin Innovation. Photo via LinkedIn

Houston researcher scores prestigious NSF award for machine learning, power grid tech

grant funding

An associate professor at the University of Houston received the highly competitive National Science Foundation CAREER Award earlier this month for a proposal focused on integrating renewable resources to improve power grids.

The award grants more than $500,000 to Xingpeng Li, assistant professor of electrical and computer engineering and leader of the Renewable Power Grid Lab at UH, to continue his work on developing ways to use machine learning to ensure that power systems can continue to run efficiently when pulling their energy from wind and solar sources, according to a statement from UH. This work has applications in the events of large disturbances to the grid.

Li explains that currently, power grids run off of converted, stored kinetic energy during grid disturbances.

"For example, when the grid experiences sudden large generation losses or increased electrical loads, the stored kinetic energy immediately converted to electrical energy and addressed the temporary shortfall in generation,” Li said in a statement. “However, as the proportion of wind and solar power increases in the grid, we want to maximize their use since their marginal costs are zero and they provide clean energy. Since we reduce the use of those traditional generators, we also reduce the power system inertia (or stored kinetic energy) substantially.”

Li plans to use machine learning to create more streamlined models that can be implemented into day-ahead scheduling applications that grid operators currently use.

“With the proposed new modeling and computational approaches, we can better manage grids and ensure it can supply continuous quality power to all the consumers," he said.

In addition to supporting Li's research and model creations, the funds will also go toward Li and his team's creation of a free, open-source tool for students from kindergarten up through their graduate studies. They are also developing an “Applied Machine Learning in Power Systems” course. Li says the course will help meet workforce needs.

The CAREER Award recognizes early-career faculty members who “have the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organization,” according to the NSF. It's given to about 500 researchers each year.

Earlier this year, Rice assistant professor Amanda Marciel was also

granted an NSF CAREER Award to continue her research in designing branch elastomers that return to their original shape after being stretched. The research has applications in stretchable electronics and biomimetic tissues.

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This article originally ran on EnergyCapital.