This week's roundup of Houston innovators includes Taylor Anne Adams of Rice University, Kelly Adels Hess of CompuCycle, and Tatiana Fofanova of Koda Health. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a podcast with an innovation leader from Rice University, the CEO of a tech recycling company, and a startup founder with fresh funding.

Taylor Anne Adams, head of venture acceleration at Lilie

Taylor Anne Adams is working to support Rice University's most ambitious entrepreneurs. Photo courtesy of Lilie

Rice University can barely keep up with the interest of students in entrepreneurial classes and programming — even in the summer.

The university's Liu Idea Lab for Innovation and Entrepreneurship offers around 30 classes a year and over a dozen co-curricular programs — all focused on supporting student entrepreneurs.

"There is a huge desire for this across the campus," Taylor Anne Adams, head of venture acceleration at Lilie, says on the Houston Innovators Podcast. "Our class enrollment has just continued to skyrocket, and we've had to add on more classes and programs and that still seems to not be enough." Continue reading.

Kelly Hess, CEO of CompuCycle

Kelly Hess leads CompuCycle, a Houston-based company focused on electronics recycling. Courtesy of CompuCycle

An innovative Houston company focused on sustainable tech recycling has expanded.

CompuCycle describes its unique Plastics Recycling System as the first and only certified, single solution e-waste recycling business. The company's unique process can now break down discarded technology products into single polymers that can then be reused in the manufacturing process.

“Properly managing all components of electronics is a cornerstone of sustainability and environmental responsibility,” Kelly Adels Hess, CEO of CompuCycle, says in a news release. “Making single polymer plastics that original equipment manufacturers (OEMs) can reuse to produce new electronics or other products, while adhering to international recycling standards, is a gamechanger for domestic companies and those that need their plastics shipped globally.” Continue reading.

Tatiana Fofanova, co-founder and CEO of Koda Health

Tatiana Fofanova, co-founder and CEO of Koda, joined the Houston Innovators Podcast to discuss her company's growth. Image via LinkedIn

Koda Health achieved a successful oversubscription of additional seed round funding thanks to the participation of AARP, Memorial Hermann Health System, and the Texas Medical Center Venture Fund. The total amount raised was undisclosed, and the round was led by Austin-based Ecliptic Capital.

The tech platform improves planning for serious illness treatment and end-of-life care using a cloud-based advance care planning, or ACP, platform that pairs with in-house support. Essentially, it allows patients to do their planning ahead and make sure that their wishes are actually put into action. According to Koda Health, this results in an average of $9,500 saved per-patient, as well as improved health outcomes.

"If we’re looking at speed of market adoption, it’s clear that Koda Health is at the forefront of a crucial transformation in Advance Care Planning," says Tatiana Fofanova, PhD, CEO of Koda Health, in a press release. “In just a few years, we’ve built out a product that now serves well over 700,000 patients nationwide for industry giants like Cigna, Privia and Houston Methodist.” Continue reading.

Taylor Anne Adams is working to support Rice University's most ambitious entrepreneurs. Photo courtesy of Lilie

Meet the Houston innovator setting student startups up for success

HOUSTON INNOVATORS PODCAST EPISODE 240

Rice University can barely keep up with the interest of students in entrepreneurial classes and programming — even in the summer.

The university's Liu Idea Lab for Innovation and Entrepreneurship offers around 30 classes a year and over a dozen co-curricular programs — all focused on supporting student entrepreneurs.

"There is a huge desire for this across the campus," Taylor Anne Adams, head of venture acceleration at Lilie, says on the Houston Innovators Podcast. "Our class enrollment has just continued to skyrocket, and we've had to add on more classes and programs and that still seems to not be enough."

One of the newest additions to the scope of Rice's offerings is the Summer Venture Studio, which launched last year and returned for 2024 with huge interest in the program that was revamped by Adams, who received her MBA at Rice. She says one of her goals was to attract a wide range of technologies and innovations, which she did with the newly announced cohort.

"In the Summer Venture Studio, we have students from undergrad and from the MBA program — we've got PhDs, we've got master's of data science, and it just creates such a vibrant cohort community here," Adams says. "It's about making sure that we're tailoring our programs across the school year as well to make sure we're touching all parts of the campus."

Adams, who's worked with various Houston organizations, including The Cannon, DivInc, and Mercury, is not only passionate about supporting the Rice startup community, but also the greater Houston network of innovators. She's currently on the founding team of The Collectiv, a Houston-based venture firm that's currently raising its first fund to invest in sports tech.

"The people here are entrepreneurial by nature. Houston was founded by entrepreneurs. Yes, we have a lot of traditional industry here, but that wasn't always the case. People had to build those industries from the ground up," Adams says. "It's in the DNA of the city."

The 12-week program received a record number of applications, that spanned the campus' degree offerings. Photo via rice.edu

Rice accelerator names innovative second summer cohort

ready to grow

Rice University's Liu Idea Lab for Innovation & Entrepreneurship, or Lilie, has named eight teams to the second cohort of the Lilie Summer Venture Studio.

The teams are focused on a range of innovative concepts, from health care solutions to running shoe design to automating recruiting from the NCAA Transfer Portal.

According to Rice, the 12-week program received a record number of applications, that spanned the campus' degree offerings.

“We are thrilled to see such a high level of interest and excitement from Rice students for a high-growth venture accelerator,” Kyle Judah, executive director of Lilie, said in a statement. “The diversity and creativity in this year's applications were truly inspiring, and we’re excited to support these promising ventures with the resources and mentorship they need to hit escape velocity and create the next generation of pillar companies for Houston, Texas and the world.”

The selected teams will receive $15,000 in non-dilutive funding from the accelerator, along with access to coworking space and personalized mentorship in the Liu Idea Lab.

Here are the teams for the 2024 Lilie Summer Venture Studio:

  • Coflux Purification, a patent-pending in-stream module that breaks down PFAS using a novel absorbent for chemical-free water
  • Docflow, focused on streamlining residency shift scheduling
  • JewelVision, building virtual fitting rooms for jewelry e-commerce retailers using generative AI
  • Levytation, using data science and AI to answer critical questions about sales and customers for coffee shop management
  • OnGuard, a marketplace to book off-duty police officers and security professionals
  • Roster, leverages data on athletes in the NCAA Transfer Portal to automatically send updates on players to coaches
  • Solidec, a technology platform that extracts molecules from water and air, transforms them into pure chemicals and fuels without any carbon emissions
  • Veloci, a running shoe venture that addresses common pains through shoe design

Lilie launched the Summer Venture Studio last year. According to Rice, two out of the six teams selected, Helix Earth Technologies and Tierra Climate, raised venture capital funds after completing the accelerator program.

Helix Earth Technologies also went on to earn the inaugural TEX-E Prize at CERAWeek in 2023.

“The track record of our Summer Venture Studio Accelerator speaks for itself, despite being early in our second year," Taylor Anne Adams, head of venture acceleration programs at the Liu Idea Lab, said in a statement. "This is the power of entrepreneurship programming that is designed by founders, for founders, that happens at the Liu Idea Lab.”


Last year, Lilie also named 11 successful business leaders with ties to Houston to its first Lilie’s Leadership Council. Each agreed to donate time and money to the university’s entrepreneurship programs. Click here to see who made the list.
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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.