Houstonian shares journey of entrepreneurship from pivot to exit to focus on inspiring positivity

HOUSTON INNOVATORS PODCAST EPISODE 247

Megan Eddings shares the full entrepreneurial journey — from founding to a pandemic pivot and an exit — on the Houston Innovators Podcast. Photo courtesy of Megan Eddings

After years of tolling over her athleisure wear startup, Megan Eddings knew what her company needed for it to be successful, and she knew she wasn't the right person to do it.

Accel Lifestyle, a clothing brand based on Edding's patented antimicrobial Prema fabric, launched late in 2019 just ahead of boutique fitness studio craze was significantly affected by the pandemic. After pivoting to face masks, including manufacturing tens of thousands for the United States Military, Eddings says she went into the next few years with Accel being back on track to design stink-resistant workout clothing.

But Eddings knew the company needed a huge marketing push to make a splash in the direct-to-consumer world.

"The core of who I am is not a social media person," she says on the Houston Innovators Podcast. "That isn't my skillset. If you sell a product, one of the only ways to become wildly successful is to have an incredible marketing strategy that you need a lot of money to build and create. That is not something that I liked.

"I was so passionate about inventing something, but in order to really scale to the next level, I would have had to take on quite a bit of investment money," she continues.

The process of figuring this out wasn't fast — and it wasn't easy, Eddings says. It took a lot of soul searching and figuring out her strengths and what was right for her.

Eddings says she started considering B2B opportunities — some of which were with major retail brands — but these companies weren't willing to make the financial commitment to Accel or its Prema fabric. The one exception was Talbots, which agreed to stock Accel's clothing.

"It was like trying to fit a round peg into a square hole for a solid year," she says, explaining the emotional and mental toll the process took on her.

Eddings says that just as the opportunity for entrepreneurship found her — by way of her husband's sweaty workout gear she felt convinced she could improve — the next opportunity for Accel found her as well. Eddings was invited to film a segment featuring Accel's products on TV.

As great of an opportunity as it was to sell Accel's products, the segment would be even more meaningful to the company. Shortly after the it aired, a man reached out to Eddings with an acquisition offer from him and his two Australian colleagues who want to build a clothing brand as big as Patagonia, Eddings says.

"When the three men flew in, we had a three-hour lunch and I felt like I was sitting with friends," Eddings says. "I decided I was going to sell, and that was pretty much it." The terms of the deal were not disclosed.

Eddings, whose background in medical sales originally brought her to Houston 12 years ago, turned back to the business world — this time tackling another new industry: oil and gas. She's now the chief strategy officer of Houston-based consultancy New Wave Offshore Energy. And as much as she likes this new role, she says she's ready to add onto her plate a new venture taking her experience with making pivots and incorporating positivity into every asset of her life.

"What I've realized is everyone wants to be happier. When I would give talks about entrepreneurship, the No. 1 question I would get as a founder is 'how do you stay so positive?'" Eddings says.

With this inspiration, she's starting a podcast — The Pivot to Positivity — and has already filmed a pilot episode of a TV show with the same focus.

"Everyone just needs more joy in their life," Eddings says.

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Houston-based Accel Lifestyle's innovative line of athleisure has made it into Talbots. Photo courtesy of Accel

Innovative Houston athleisure startup debuts in Talbots

ready-to-wear innovation

After a year of planning and behind-the-scenes work, the highly anticipated collaboration between local apparel brand Accel Lifestyle and Talbots has finally come to fruition.

Shoppers can now find Accel Lifestyle apparel — beloved for its eco-friendly, sustainable, antibacterial fabrics sourced made in the USA — on Talbot's website.

This partnership marks the first-ever collaboration for the athleisure brand of Talbots, T by Talbots. By teaming up with Accel Lifestyle, Talbots expands its product offerings and also provides its loyal, forward-thinking, and ethically minded customers with a new clothing option that perfectly fits with their values.

At the helm of Accel Lifestyle is founder Megan Eddings, whose background in chemistry ignited the creation of the brand's groundbreaking Prema fabric after one too many run-ins with foul-smelling gym clothes. Her proprietary fabric boasts a revolutionary antibacterial technology, rendering Accel Lifestyle's apparel supremely comfortable, high-quality, and remarkably odor-resistant. With this cutting-edge fabric, Accel Lifestyle firmly establishes itself as a trailblazer in the industry, setting new standards for functionality and style.

As CultureMap reported in 2019, Eddings's innovative work was rewarded with a partnership with Inc. Magazine, Houston billionaire Tilman Fertitta, and others.

Amanda Cotler and Megan Eddings of Accel Lifestyle are celebrating a big win for their company. Photo courtesy

"We are beyond elated about the Accel x Talbots launch," Eddings tells CultureMap." Amanda Cotler, Accel's Director of Operations, and I have been working on this opportunity for a year, and it feels incredible for the collaboration to be live. Our passions are textiles with technology and an ethical made-in-the-USA supply chain. To have a multi-billion dollar company like Talbots care about the same things brings us so much joy."

In addition to their remarkable achievements in fashion, Accel Lifestyle champions the power of women in STEM through their team's leadership and this collaboration. By showcasing the applications of science and technology within the realm of fashion, Accel Lifestyle and Talbots are spotlighting the remarkable potential within these fields.

With the Accel Lifestyle x Talbots collaboration in full swing, customers can expect an extraordinary fusion of sustainable fashion and impeccable style. The Accel Lifestyle collaboration features an Anti-Odor Power Tank and an Anti-Odor Timeless Tee. Both are available in colors black and white.

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This article originally ran on CultureMap.

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Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.

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