Houston named growing hub for life sciences, cybersecurity startups win contest, and more innovation news

short stories

In this roundup of short stories, Houston has been recognized as an emerging hub for life sciences, HCC wins an award for entrepreneurship, and more local innovation news. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, see why Houston has been named a top emerging hub for life sciences, Hatch Pitch reveals its cybersecurity startup winners, and more.

Houston named an emerging life science hub

A new report finds that Houston's life sciences scene — soon to be home to TMC3 — is growing. Courtesy of Elkus Manfredi Architects

According to a new report from CBRE, Houston is on track to be a top market for life sciences. The report factored in size and growth of life-sciences employment, the venture capital and National Institutes of Health funding, and more.

"Interest in Houston's life sciences sector from developers, investors and financial backers has grown significantly in recent years," says Nelson Udstuen, senior vice president at CBRE, in a press release. "Several factors have contributed to this, including an increase in both federal funding from NIH and private venture capital, a growth in R&D employment and commitments from Texas Medical Center member institutions and other private developers to establish new life science buildings and campuses."

Houston's life-sciences industry, which comes in at No. 2 on the list behind Pittsburgh and ahead of Austin, ranks within the 20 largest in the U.S. by employment. In terms of growth, Houston is expanding at a 6.5 percent pace from 2018 to 2019. Houston institutes received around $600 million in funding from NIH last year, which amounted to the 12th-largest sum by market.

"Houston is also a draw for the life sciences industry due to its large cluster of life science employees," continues Udstuen. "Our market is home to a large population with the technical ability to perform Research and Development, meaning employers do not have to focus as heavily on recruiting from other markets."

Inaugural pitch competition names winners

pitch

Hatch Pitch named the winners of its inaugural cybersecurity-focused competition. Photo via Getty Images

Houston-based Hatch Pitch announced its Cyber Pitch competition in December, and, other than having to pivot to virtual, the competition went off without a hitch. The winners at the Houston Cyber Summit were revealed on October 22.

  • Toronto-based Paqt took first place
  • PixoAnalytics, based in Bonn, Germany, came in second
  • And Austin-based Clocr placed in third place as well as the Audience Favorite.

Hatch Pitch will return in March 2021 for the Hatch Pitch Digital Summit, but until then, check out video clips and the pitches from Cyber Pitch 2020 online.

Houston college receives national entrepreneurship award

Houston Community College has been named the 2020 Heather Van Sickle Entrepreneurial College of the Year. Photo via HCC.edu

The National Association for Community College Entrepreneurship has named Houston Community College as the 2020 Heather Van Sickle Entrepreneurial College of the Year at its 18th Annual Conference in Nashville, Tennessee, earlier this month.

"Houston Community College is a model of how colleges contribute to their local entrepreneurial ecosystems," says Rebecca Corbin, president and CEO of NACCE, in a news release. "Through persistence and entrepreneurial mindset and action, HCC has scaled replicable and sustainable entrepreneurial programs that have impacted thousands of students over the past several years. It is a pleasure to recognize this outstanding college, which was selected by an independent judging panel, as the winner of NACCE's 2020 Entrepreneurial College of the Year Award."

Energy tech startup names new CEO

Tachyus has a new head honcho. Photo via tachyus.com

Data-focused energy software startup Tachyus has announced the promotion of Fernando Gutierrez to CEO — formerly vice president of customer success.

"We are in a unique time within the upstream oil and gas space, and I truly believe Tachyus has the ability to pioneer the acceleration of the digital transformation within the industry," says Gutierrez, in a news release. "We are at the intersection of innovation and conventionalism, and I'm excited to lead the organization in a movement that continues to establish our technical solutions with our unique product signature."

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform. Last year, the company raised $15 million in a round led by Houston-based Cottonwood Venture Partners.

Former CEO and Co-Founder Paul Orland has assumed the role of chairman.

Female founder selected for new program backed by Houston organization

Kim Roxie, founder of LAMIK Beauty, is among the 15 recipients of a new initiative. Photo via stacysrise.helloalice.com

Plano, Texas-based Stacy's Rise Project expanded its annual grant and mentorship program in order to give more aid to Black female business founders, who on average only receive 0.2 percent of venture capitalist funding, according to a press release. The organization teamed up with its longtime partner, Houston-founded Hello Alice, to back an additional 15 Black female founders with a total of $150,000.

Among the 15 recipients was Houston's own Kim Roxie of LAMIK Beauty. LAMIK Beauty is a beauty-tech company designed for multicultural women with products made with natural and organic ingredients.

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Houston-based Tachyus closed a $15 million Series B round. Photo courtesy of Thomas Miller/Breitling Energy

Houston oil and gas software company closes $15 million round led by local PE firm

Money on the mind

It's pay day for Houston-based Tachyus. the data-driven software company has closed its Series B fundraising round at $15 million. The round was led by Houston-based Cottonwood Venture Partners, a private equity firm that funds companies using technology to solve problems within the energy industry.

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform.

"In this economic environment, oil and gas operators need disruptive tools to optimize their fields," Tachyus CEO and co-founder, Paul Orland, says in a release. "This investment allows us to reach more customers and accelerate the delivery of new technology that improves our clients' business performance."

The company has already grown its client base and has customers in Argentina, Europe, and Asia. Tachyus joins several other tech-focused energy startups in CVP's portfolio, including Ambyint, Novi Labs, and SitePro. Houston-based Tudor, Pickering, Holt & Co. served Tachyus as its financial adviser.

"As the oil and gas industry evolves in the face of new commercial challenges, operators need to focus on getting the best performance from their assets, and Tachyus' technology has a track record of doing just that," says Jeremy Arendt, managing partner of CVP, in the release. "We are excited to partner with the Tachyus team to expand their reach and empower customers to optimize production across their fields."

Tachyus closed its last round in 2016 with a $4 million investment from Primwest, according to CrunchBase. Before that, the company had raised several million.

Last year, the startup restructured its C-suite. Tachyus co-founder Dakin Sloss transitioned from CEO to chairman, and Orland, who was previously CTO, took the reins, according to a release.

Paul Orland is CEO of Tachyus. Photo via tachyus.com

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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