Houston named growing hub for life sciences, cybersecurity startups win contest, and more innovation news

short stories

In this roundup of short stories, Houston has been recognized as an emerging hub for life sciences, HCC wins an award for entrepreneurship, and more local innovation news. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, see why Houston has been named a top emerging hub for life sciences, Hatch Pitch reveals its cybersecurity startup winners, and more.

Houston named an emerging life science hub

A new report finds that Houston's life sciences scene — soon to be home to TMC3 — is growing. Courtesy of Elkus Manfredi Architects

According to a new report from CBRE, Houston is on track to be a top market for life sciences. The report factored in size and growth of life-sciences employment, the venture capital and National Institutes of Health funding, and more.

"Interest in Houston's life sciences sector from developers, investors and financial backers has grown significantly in recent years," says Nelson Udstuen, senior vice president at CBRE, in a press release. "Several factors have contributed to this, including an increase in both federal funding from NIH and private venture capital, a growth in R&D employment and commitments from Texas Medical Center member institutions and other private developers to establish new life science buildings and campuses."

Houston's life-sciences industry, which comes in at No. 2 on the list behind Pittsburgh and ahead of Austin, ranks within the 20 largest in the U.S. by employment. In terms of growth, Houston is expanding at a 6.5 percent pace from 2018 to 2019. Houston institutes received around $600 million in funding from NIH last year, which amounted to the 12th-largest sum by market.

"Houston is also a draw for the life sciences industry due to its large cluster of life science employees," continues Udstuen. "Our market is home to a large population with the technical ability to perform Research and Development, meaning employers do not have to focus as heavily on recruiting from other markets."

Inaugural pitch competition names winners

pitch

Hatch Pitch named the winners of its inaugural cybersecurity-focused competition. Photo via Getty Images

Houston-based Hatch Pitch announced its Cyber Pitch competition in December, and, other than having to pivot to virtual, the competition went off without a hitch. The winners at the Houston Cyber Summit were revealed on October 22.

  • Toronto-based Paqt took first place
  • PixoAnalytics, based in Bonn, Germany, came in second
  • And Austin-based Clocr placed in third place as well as the Audience Favorite.

Hatch Pitch will return in March 2021 for the Hatch Pitch Digital Summit, but until then, check out video clips and the pitches from Cyber Pitch 2020 online.

Houston college receives national entrepreneurship award

Houston Community College has been named the 2020 Heather Van Sickle Entrepreneurial College of the Year. Photo via HCC.edu

The National Association for Community College Entrepreneurship has named Houston Community College as the 2020 Heather Van Sickle Entrepreneurial College of the Year at its 18th Annual Conference in Nashville, Tennessee, earlier this month.

"Houston Community College is a model of how colleges contribute to their local entrepreneurial ecosystems," says Rebecca Corbin, president and CEO of NACCE, in a news release. "Through persistence and entrepreneurial mindset and action, HCC has scaled replicable and sustainable entrepreneurial programs that have impacted thousands of students over the past several years. It is a pleasure to recognize this outstanding college, which was selected by an independent judging panel, as the winner of NACCE's 2020 Entrepreneurial College of the Year Award."

Energy tech startup names new CEO

Tachyus has a new head honcho. Photo via tachyus.com

Data-focused energy software startup Tachyus has announced the promotion of Fernando Gutierrez to CEO — formerly vice president of customer success.

"We are in a unique time within the upstream oil and gas space, and I truly believe Tachyus has the ability to pioneer the acceleration of the digital transformation within the industry," says Gutierrez, in a news release. "We are at the intersection of innovation and conventionalism, and I'm excited to lead the organization in a movement that continues to establish our technical solutions with our unique product signature."

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform. Last year, the company raised $15 million in a round led by Houston-based Cottonwood Venture Partners.

Former CEO and Co-Founder Paul Orland has assumed the role of chairman.

Female founder selected for new program backed by Houston organization

Kim Roxie, founder of LAMIK Beauty, is among the 15 recipients of a new initiative. Photo via stacysrise.helloalice.com

Plano, Texas-based Stacy's Rise Project expanded its annual grant and mentorship program in order to give more aid to Black female business founders, who on average only receive 0.2 percent of venture capitalist funding, according to a press release. The organization teamed up with its longtime partner, Houston-founded Hello Alice, to back an additional 15 Black female founders with a total of $150,000.

Among the 15 recipients was Houston's own Kim Roxie of LAMIK Beauty. LAMIK Beauty is a beauty-tech company designed for multicultural women with products made with natural and organic ingredients.

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Houston-based Tachyus closed a $15 million Series B round. Photo courtesy of Thomas Miller/Breitling Energy

Houston oil and gas software company closes $15 million round led by local PE firm

Money on the mind

It's pay day for Houston-based Tachyus. the data-driven software company has closed its Series B fundraising round at $15 million. The round was led by Houston-based Cottonwood Venture Partners, a private equity firm that funds companies using technology to solve problems within the energy industry.

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform.

"In this economic environment, oil and gas operators need disruptive tools to optimize their fields," Tachyus CEO and co-founder, Paul Orland, says in a release. "This investment allows us to reach more customers and accelerate the delivery of new technology that improves our clients' business performance."

The company has already grown its client base and has customers in Argentina, Europe, and Asia. Tachyus joins several other tech-focused energy startups in CVP's portfolio, including Ambyint, Novi Labs, and SitePro. Houston-based Tudor, Pickering, Holt & Co. served Tachyus as its financial adviser.

"As the oil and gas industry evolves in the face of new commercial challenges, operators need to focus on getting the best performance from their assets, and Tachyus' technology has a track record of doing just that," says Jeremy Arendt, managing partner of CVP, in the release. "We are excited to partner with the Tachyus team to expand their reach and empower customers to optimize production across their fields."

Tachyus closed its last round in 2016 with a $4 million investment from Primwest, according to CrunchBase. Before that, the company had raised several million.

Last year, the startup restructured its C-suite. Tachyus co-founder Dakin Sloss transitioned from CEO to chairman, and Orland, who was previously CTO, took the reins, according to a release.

Paul Orland is CEO of Tachyus. Photo via tachyus.com

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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