Houston named growing hub for life sciences, cybersecurity startups win contest, and more innovation news

short stories

In this roundup of short stories, Houston has been recognized as an emerging hub for life sciences, HCC wins an award for entrepreneurship, and more local innovation news. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, see why Houston has been named a top emerging hub for life sciences, Hatch Pitch reveals its cybersecurity startup winners, and more.

Houston named an emerging life science hub

A new report finds that Houston's life sciences scene — soon to be home to TMC3 — is growing. Courtesy of Elkus Manfredi Architects

According to a new report from CBRE, Houston is on track to be a top market for life sciences. The report factored in size and growth of life-sciences employment, the venture capital and National Institutes of Health funding, and more.

"Interest in Houston's life sciences sector from developers, investors and financial backers has grown significantly in recent years," says Nelson Udstuen, senior vice president at CBRE, in a press release. "Several factors have contributed to this, including an increase in both federal funding from NIH and private venture capital, a growth in R&D employment and commitments from Texas Medical Center member institutions and other private developers to establish new life science buildings and campuses."

Houston's life-sciences industry, which comes in at No. 2 on the list behind Pittsburgh and ahead of Austin, ranks within the 20 largest in the U.S. by employment. In terms of growth, Houston is expanding at a 6.5 percent pace from 2018 to 2019. Houston institutes received around $600 million in funding from NIH last year, which amounted to the 12th-largest sum by market.

"Houston is also a draw for the life sciences industry due to its large cluster of life science employees," continues Udstuen. "Our market is home to a large population with the technical ability to perform Research and Development, meaning employers do not have to focus as heavily on recruiting from other markets."

Inaugural pitch competition names winners

pitch

Hatch Pitch named the winners of its inaugural cybersecurity-focused competition. Photo via Getty Images

Houston-based Hatch Pitch announced its Cyber Pitch competition in December, and, other than having to pivot to virtual, the competition went off without a hitch. The winners at the Houston Cyber Summit were revealed on October 22.

  • Toronto-based Paqt took first place
  • PixoAnalytics, based in Bonn, Germany, came in second
  • And Austin-based Clocr placed in third place as well as the Audience Favorite.

Hatch Pitch will return in March 2021 for the Hatch Pitch Digital Summit, but until then, check out video clips and the pitches from Cyber Pitch 2020 online.

Houston college receives national entrepreneurship award

Houston Community College has been named the 2020 Heather Van Sickle Entrepreneurial College of the Year. Photo via HCC.edu

The National Association for Community College Entrepreneurship has named Houston Community College as the 2020 Heather Van Sickle Entrepreneurial College of the Year at its 18th Annual Conference in Nashville, Tennessee, earlier this month.

"Houston Community College is a model of how colleges contribute to their local entrepreneurial ecosystems," says Rebecca Corbin, president and CEO of NACCE, in a news release. "Through persistence and entrepreneurial mindset and action, HCC has scaled replicable and sustainable entrepreneurial programs that have impacted thousands of students over the past several years. It is a pleasure to recognize this outstanding college, which was selected by an independent judging panel, as the winner of NACCE's 2020 Entrepreneurial College of the Year Award."

Energy tech startup names new CEO

Tachyus has a new head honcho. Photo via tachyus.com

Data-focused energy software startup Tachyus has announced the promotion of Fernando Gutierrez to CEO — formerly vice president of customer success.

"We are in a unique time within the upstream oil and gas space, and I truly believe Tachyus has the ability to pioneer the acceleration of the digital transformation within the industry," says Gutierrez, in a news release. "We are at the intersection of innovation and conventionalism, and I'm excited to lead the organization in a movement that continues to establish our technical solutions with our unique product signature."

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform. Last year, the company raised $15 million in a round led by Houston-based Cottonwood Venture Partners.

Former CEO and Co-Founder Paul Orland has assumed the role of chairman.

Female founder selected for new program backed by Houston organization

Kim Roxie, founder of LAMIK Beauty, is among the 15 recipients of a new initiative. Photo via stacysrise.helloalice.com

Plano, Texas-based Stacy's Rise Project expanded its annual grant and mentorship program in order to give more aid to Black female business founders, who on average only receive 0.2 percent of venture capitalist funding, according to a press release. The organization teamed up with its longtime partner, Houston-founded Hello Alice, to back an additional 15 Black female founders with a total of $150,000.

Among the 15 recipients was Houston's own Kim Roxie of LAMIK Beauty. LAMIK Beauty is a beauty-tech company designed for multicultural women with products made with natural and organic ingredients.

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Houston-based Tachyus closed a $15 million Series B round. Photo courtesy of Thomas Miller/Breitling Energy

Houston oil and gas software company closes $15 million round led by local PE firm

Money on the mind

It's pay day for Houston-based Tachyus. the data-driven software company has closed its Series B fundraising round at $15 million. The round was led by Houston-based Cottonwood Venture Partners, a private equity firm that funds companies using technology to solve problems within the energy industry.

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform.

"In this economic environment, oil and gas operators need disruptive tools to optimize their fields," Tachyus CEO and co-founder, Paul Orland, says in a release. "This investment allows us to reach more customers and accelerate the delivery of new technology that improves our clients' business performance."

The company has already grown its client base and has customers in Argentina, Europe, and Asia. Tachyus joins several other tech-focused energy startups in CVP's portfolio, including Ambyint, Novi Labs, and SitePro. Houston-based Tudor, Pickering, Holt & Co. served Tachyus as its financial adviser.

"As the oil and gas industry evolves in the face of new commercial challenges, operators need to focus on getting the best performance from their assets, and Tachyus' technology has a track record of doing just that," says Jeremy Arendt, managing partner of CVP, in the release. "We are excited to partner with the Tachyus team to expand their reach and empower customers to optimize production across their fields."

Tachyus closed its last round in 2016 with a $4 million investment from Primwest, according to CrunchBase. Before that, the company had raised several million.

Last year, the startup restructured its C-suite. Tachyus co-founder Dakin Sloss transitioned from CEO to chairman, and Orland, who was previously CTO, took the reins, according to a release.

Paul Orland is CEO of Tachyus. Photo via tachyus.com

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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