Texas-based travel brand unpacks stylish and affordable luggage

Wheels up

Suitcase company, Tiko, raised $100,000 in its first crowdfunding campaign. Courtesy photo

If Marcus Segui's successful 2016 Kickstarter is any indication, people are looking for innovative ways to make traveling a little easier. With that intention in mind, Segui launched Tiko, a Texas-based travel brand shaking up the industry by providing affordable, beautifully designed, quality luggage to passengers across the world.

On November 1, Tiko rolled into the world with its signature carry-on, priced at $195, and designed to fit in overhead bins (a must for those of us who find baggage fees insulting). Available only online, the company's first bag comes with 360-degree spinning wheels, and is offered in charcoal and gray.

For the Texas-born Segui, the idea for his company was born out of one thing: he travels — a lot. After a career in finance in New York, Segui traveled to Colombia, a trip that ended up lasting three years. "I got a Spanish tutor, found an apartment, and started looking for a way to do business," Segui says. "Before long I linked up with a local investment fund who asked me to launch a real estate company for them."

"Running a business in Spanish was really hard," he jokes, and by the time Segui decided to leave Colombia, he had logged countless flights across South and Central America. The University of Texas grad eventually made his way back to Austin with a busted carry-on in tow.

"After my time in New York and South America, I decided to return to Austin for two reasons: friends and family. Every entrepreneur needs to lean on their network to get a new company off the ground," he says.

And oh how that network helped. Unable to find a carry-on replacement that was both durable and affordable, Segui got the idea for a direct-to-consumer luggage company designed to bypass retailers and thus cut the price point for the luggage in half.

Segui began development on a series of prototypes, eventually landed on Tiko's current carry-on model, and decided to launch a Kickstarter to gauge interest (and funds, of course). The campaign raised over $100,000, allowing Segui to take off with the new company.

In order to move the company into its next phase, Segui assembled a who's who team of tech talent, including former execs from YETI and Airbnb. Earlier this month, the company officially launched its first product from its coworking space headquarters in South Austin.

A few weeks into the new endeavor, it remains to be seen if the public will embrace Tiko, but its launch points to a growing trend: consumers are demanding a different travel experience. Suddenly, people are beginning to question the inconvenient, expensive, and yes, unstylish things that must be endured in order to get from one point to another.

Perhaps one day we'll return to that glamorous apex of airline travel, the time where no one wore pajamas and passengers didn't have to line up like cattle to board the aircraft. Until then, at least we can have nice luggage.

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This story originally appeared on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

New accelerator joins the Ion and more Houston innovation news to know

Trending News

Editor's note: The Houston innovation scene is buzzing with big news this month, from a new accelerator joining the fold at the Ion to pre-IPO funding and national expansion plans. Below are the five most-read InnovationMap stories from Feb. 1-15, 2026:

New accelerator for AI startups to launch at Houston's Ion this spring

The new AI Native Dual-Use Sports, Health & Wellness Accelerator is expected to launch in March. Photo courtesy of the Ion

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform. The AI Native Dual-Use Sports, Health & Wellness Accelerator is scheduled to formally launch in March. Continue reading.

10+ can't-miss Houston business and innovation events in February

From recurring monthly favorites to the return of annual celebrations and summits, here's what not to miss in February. Photo courtesy the Ion.

February may be a short month, but its event calendar isn’t. From recurring monthly favorites to the return of annual celebrations and summits, here are the Houston business and innovation events not to miss — and how to register. Continue reading.

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