Suitcase company, Tiko, raised $100,000 in its first crowdfunding campaign. Courtesy photo

If Marcus Segui's successful 2016 Kickstarter is any indication, people are looking for innovative ways to make traveling a little easier. With that intention in mind, Segui launched Tiko, a Texas-based travel brand shaking up the industry by providing affordable, beautifully designed, quality luggage to passengers across the world.

On November 1, Tiko rolled into the world with its signature carry-on, priced at $195, and designed to fit in overhead bins (a must for those of us who find baggage fees insulting). Available only online, the company's first bag comes with 360-degree spinning wheels, and is offered in charcoal and gray.

For the Texas-born Segui, the idea for his company was born out of one thing: he travels — a lot. After a career in finance in New York, Segui traveled to Colombia, a trip that ended up lasting three years. "I got a Spanish tutor, found an apartment, and started looking for a way to do business," Segui says. "Before long I linked up with a local investment fund who asked me to launch a real estate company for them."

"Running a business in Spanish was really hard," he jokes, and by the time Segui decided to leave Colombia, he had logged countless flights across South and Central America. The University of Texas grad eventually made his way back to Austin with a busted carry-on in tow.

"After my time in New York and South America, I decided to return to Austin for two reasons: friends and family. Every entrepreneur needs to lean on their network to get a new company off the ground," he says.

And oh how that network helped. Unable to find a carry-on replacement that was both durable and affordable, Segui got the idea for a direct-to-consumer luggage company designed to bypass retailers and thus cut the price point for the luggage in half.

Segui began development on a series of prototypes, eventually landed on Tiko's current carry-on model, and decided to launch a Kickstarter to gauge interest (and funds, of course). The campaign raised over $100,000, allowing Segui to take off with the new company.

In order to move the company into its next phase, Segui assembled a who's who team of tech talent, including former execs from YETI and Airbnb. Earlier this month, the company officially launched its first product from its coworking space headquarters in South Austin.

A few weeks into the new endeavor, it remains to be seen if the public will embrace Tiko, but its launch points to a growing trend: consumers are demanding a different travel experience. Suddenly, people are beginning to question the inconvenient, expensive, and yes, unstylish things that must be endured in order to get from one point to another.

Perhaps one day we'll return to that glamorous apex of airline travel, the time where no one wore pajamas and passengers didn't have to line up like cattle to board the aircraft. Until then, at least we can have nice luggage.

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This story originally appeared on CultureMap.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.