Suitcase company, Tiko, raised $100,000 in its first crowdfunding campaign. Courtesy photo

If Marcus Segui's successful 2016 Kickstarter is any indication, people are looking for innovative ways to make traveling a little easier. With that intention in mind, Segui launched Tiko, a Texas-based travel brand shaking up the industry by providing affordable, beautifully designed, quality luggage to passengers across the world.

On November 1, Tiko rolled into the world with its signature carry-on, priced at $195, and designed to fit in overhead bins (a must for those of us who find baggage fees insulting). Available only online, the company's first bag comes with 360-degree spinning wheels, and is offered in charcoal and gray.

For the Texas-born Segui, the idea for his company was born out of one thing: he travels — a lot. After a career in finance in New York, Segui traveled to Colombia, a trip that ended up lasting three years. "I got a Spanish tutor, found an apartment, and started looking for a way to do business," Segui says. "Before long I linked up with a local investment fund who asked me to launch a real estate company for them."

"Running a business in Spanish was really hard," he jokes, and by the time Segui decided to leave Colombia, he had logged countless flights across South and Central America. The University of Texas grad eventually made his way back to Austin with a busted carry-on in tow.

"After my time in New York and South America, I decided to return to Austin for two reasons: friends and family. Every entrepreneur needs to lean on their network to get a new company off the ground," he says.

And oh how that network helped. Unable to find a carry-on replacement that was both durable and affordable, Segui got the idea for a direct-to-consumer luggage company designed to bypass retailers and thus cut the price point for the luggage in half.

Segui began development on a series of prototypes, eventually landed on Tiko's current carry-on model, and decided to launch a Kickstarter to gauge interest (and funds, of course). The campaign raised over $100,000, allowing Segui to take off with the new company.

In order to move the company into its next phase, Segui assembled a who's who team of tech talent, including former execs from YETI and Airbnb. Earlier this month, the company officially launched its first product from its coworking space headquarters in South Austin.

A few weeks into the new endeavor, it remains to be seen if the public will embrace Tiko, but its launch points to a growing trend: consumers are demanding a different travel experience. Suddenly, people are beginning to question the inconvenient, expensive, and yes, unstylish things that must be endured in order to get from one point to another.

Perhaps one day we'll return to that glamorous apex of airline travel, the time where no one wore pajamas and passengers didn't have to line up like cattle to board the aircraft. Until then, at least we can have nice luggage.

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This story originally appeared on CultureMap.

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European spacecraft developer expands to Houston with U.S. business, new lab

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European aerospace manufacturer The Exploration Company has established its first U.S. entity and named Space City as its headquarters.

The company announced earlier this month that it has launched TEC Federal to support U.S. government customers and agencies, and to scale The Exploration Company's engineering operations in the country.

Mark Kirasich serves as president of TEC Federal. Kirasich most recently served as the senior director of human spaceflight at Blue Origin after a nearly 40-year career at NASA.

The Exploration Company is developing the reusable Nyx space vehicle. Nyx is designed to take off from any heavy launcher in the world. It will then dock at space stations, retrieve up to 3,000 kilograms of cargo, splash down and return the cargo to Earth. The company aims to make Nyx fully reusable for up to 10 missions, making it a more affordable and sustainable option for aerospace missions.

The Exploration Company completed a successful drop test of the spacecraft in May in the Mojave Desert. The company says Nyx is slated to perform its first flight demonstration in 2028.

In addition to launching the Houston business, The Exploration Company also opened its new Rapid Innovation Lab near Houston's NASA Johnson Space Center on Space Park Drive.

The Exploration Company opened its Rapid Innovation Lab earlier this month. Photo via LinkedIn

The Rapid Innovation Lab features a full-scale mockup of the future Nyx crew capsule as well as ongoing development and testing of the Nyx cargo capsule, according to the company.

The Exploration Company says the new lab will allow its engineers, designers, and operators to prototype and test crew interfaces. It will also support partnerships with NASA personnel and astronauts.

“Houston gives us direct access to the people and expertise that have built and operated human spaceflight systems for decades. We’re excited to invest and expand around that— engineers, operators, and astronauts working together and moving quickly towards building a crew capsule.” Hélène Huby, founder and CEO of The Exploration Company, said in a blog post.

According to The Houston Chronicle, The Exploration Company has about 30 employees in the Houston area.

The company was founded in 2021 by Huby, a French rocket scientist, and has raised more than $350 million in venture capital. It operates out of Germany, France, Luxembourg, Spain and Italy, with offices in the U.S. and the United Arab Emirates. It is also developing a reusable, high-thrust rocket engine known as Storm.

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.