Early and effective stakeholder outreach is a key part of a successful project. Getty Images

Often times we think of technology as innovation. But innovation and the success derived from it is not always about technological advances.

Technological advances have driven innovation in all sectors of our economy. Technology and social media have driven social change and changed how stakeholders— the public and outside influencers — impact infrastructure and construction projects, and how they advocate with policy leaders. This includes the energy, utilities, infrastructure, real estate projects, and manufacturing industries.

Often times the innovation from technology is about a new way of thinking and how one adapts to, works with, and embraces technology and how it impacts a business or an industry. It is about a willingness to do things differently because technology now drives us to think creatively and differently than in the past. It is taking a new approach to how one manages risk, solves problems and meets the challenges facing a business or an industry.

Technology has changed how we communicate as a culture. It has changed how the public communicates with business and how business has to communicate with the public. Because of the growth and influence of social media in our culture, business must now mange a new kind of risk in the risk register of a project. It has to change how it interacts and communicates with stakeholders. It has to be more attentive and listen actively compared to how it operated in the past. Gone are the days when a project manager, private equity firm/investor or company developing a project can "keep their head down so they don't get shot at."

I listed the many industries that are impacted by social media. There is no better example of an industry that has had to change and use innovative and new ways of communicating due to technology. Regardless of the energy project, the development of oil & gas, building a pipeline, new utility lines, a refinery or chemical facility the industry now has to assess who their stakeholders are, listen to them attentively, and develop a strategic plan for outreach. If a company changes how they interact with stakeholders the associated risks will be minimized, mitigated and/or reduced.

There are a plethora of energy projects I can list that highlight how a business failed to innovate in response to how they failed to adapt to, work with and embrace the technology of social media and how it impacts them. One project sums it up, Keystone.

Effective stakeholder outreach has four parts: identification, analysis, prioritization and engagement.

Identification
The first step is to identify the stakeholders. This includes those who will be directly or indirectly impacted such as local, state and federal political leaders, NGOs, media, faith-based groups, landowners, civic leaders, nearby businesses and advocacy groups.

Analysis
The analysis is an evaluation of possible risks related to the stakeholders and the community where the project is planned such as stakeholders who might be opposed to the project, have concerns or be able to influence the process in any way. Have there been issues in the community or legislative bodies that might have a negative impact?

Prioritization
Prioritization is the process of taking the results from the analysis of stakeholders and determining what risks or issues exist. These risks are ranked. Strategies and tactics are developed to address and mitigate them. Finally, a determination is made regarding how and when to communicate with stakeholders.

Engagement
Engagement is the final part of stakeholder outreach. This is the process of communicating with stakeholders to explain the project and how they will be impacted. It will also serve as an opportunity to solicit feedback and insight as well as to continue analyzing risks from stakeholders.

Early and effective stakeholder outreach is a key part of a successful project. It is a new and innovative way of thinking about how to understand and mitigate project risk. It is a willingness to change because technology has shifted how our culture communicates, advocates and engages with business, policy leaders and one another.

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Andrew Biar is founder and president of Strategic Public Affairs, a government relations and PR/communications firm based in Houston.
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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."