Common Desk, which has locations across Houston, has been acquired — and other innovation news. Rendering courtesy of Common Desk

Houston is starting 2022 strong in terms of innovation news, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, the Bayou City is ranked based on its opportunities for STEM jobs, a Houston blockchain startup scores a major contract, Rice University opens applications for its veteran-owned business competition, and more.

Data Gumbo announces contract with Equinor

After a successful pilot, Equinor has signed off on a contract with Data Gumbo.. Courtesy of Data Gumbo

Houston-based Data Gumbo, an industrial blockchain-software-as-a-service company, announced that it has signed a contract with Equinor. The global energy company's venture arm, Equinor Ventures, supported the startup's $7.7 million series B round, which closed last year.

The company's technology features smart contract automation and execution, which reduces contract leakage, frees up working capital, enables real-time cash and financial management, and delivers provenance with unprecedented speed, accuracy, visibility and transparency, per the release.

“Equinor is an industry trailblazer, demonstrating the true value of our international smart contract network to improve and automate manual processes, and bring trust to all parties,” says Andrew Bruce, founder and CEO of Data Gumbo, in a news release. “Smart contracts are playing a critical role in driving the energy industry forward. Our work with Equinor clearly demonstrates the benefits that supermajors and their supply chain customers, partners and vendors experience by automating commercial transactions. We are proud to continue our work with Equinor to help them realize the savings, efficiencies and new levels of transparency available through our smart contract network.”

Equinor opted into a pilot with the company a few years ago.

“Since piloting Data Gumbo’s smart contracts for offshore drilling services in 2019, we have worked with the company to continually refine and improve use cases. We now have the potential to expand Data Gumbo’s smart contract network to enable transactional certainty across our portfolio from the Norwegian Continental Shelf to our Brazilian operated assets and beyond,” says Erik Kirkemo, senior vice president at Equinor. “GumboNet reduces inefficiencies and processing time around contract execution in complex supply chains, which is a problem in the broader industry, and we look forward to realizing the streamlined process and cost savings of its rapidly expanding smart contract network.”

WeWork acquires Dallas coworking brand with 6 Houston locations

Common Desk, which has six locations in Houston including in The Ion, has been acquired. Photo courtesy of Common Desk

Dallas-based Common Desk, which has six locations in Houston, announced its acquisition by WeWork. The company's office spaces will be branded as “Common Desk, a WeWork Company,” according to a news release.

“Similar to WeWork, Common Desk is a company built on the concept of bringing people together to have their best day at work," says Nick Clark, CEO at Common Desk, in the release. "With the added support from WeWork, Common Desk will be able to not only leverage WeWork’s decade of experience in member services to improve the experience of our own members but also leverage WeWork’s impressive client roster to further build out our member base.”

Here are the six Common Desk spaces in Houston:

Here's how Houston ranks as a metro for STEM jobs

Source: WalletHub

When it comes to the best cities for jobs in science, technology, engineering, and math, Houston ranks in the middle of the pack. The greater Houston area ranked at No. 37 among the 100 largest metros across 19 key metrics on the list compiled by personal finance website, WalletHub. Here's how Houston fared on the report's metrics:

  • No. 36 – percent of Workforce in STEM
  • No. 74 – STEM Employment Growth
  • No. 43 – Math Performance
  • No. 16 – Quality of Engineering Universities
  • No. 2 – Annual Median Wage for STEM Workers (Adjusted for Cost of Living)
  • No. 90 – Median Wage Growth for STEM Workers
  • No. 75 – Job Openings for STEM Graduates per Capita
  • No. 88 – Unemployment Rate for Adults with at Least a Bachelor’s Degree

Elsewhere in Texas, Austin ranked at No. 2 overall, and Dallas just outranked Houston coming in at No. 34. San Antonio, El Paso, and McAllen ranked No. 51, No. 65, and No. 88, respectively.

Rice University calls for contestants for its 8th annual startup pitch competition for veterans

Calling all veteran and active duty startup founders and business owners. Photo courtesy of Rice University

Rice University is now accepting applications from Houston veterans for its annual business competition. To apply for the 2022 Veterans Business Battle, honorably discharged veterans or active duty founders can head online to learn more and submit their business plan by Feb. 15.

“We’re looking forward to giving veterans the opportunity not just to share their ideas and get financing, but learn from other past winners the lessons about entrepreneurship they’ve lived through while growing their businesses,” event co-chair Reid Schrodel says in a news release.

Over the past few years, finalists have received more than $4 million of investments through the program. This year's monetary prizes add up to $30,000 — $15,000 prize for first place, $10,000 for second place, and $5,000 for third place.

Finalists will be invited to make their business pitch April 22 and 23 at Rice University. Click here to register for the event.

City of Houston receives grant to stimulate STEM opportunities

Houston's youth population is getting a leg up on STEM opportunities. Photo via Getty Images

Thanks to a $150,000 grant from the National League of Cities, the city of Houston has been awarded a chance to provide quality education and career opportunities to at-risk young adults and students. The city is one of five cities also selected to receive specialized assistance from NLC’s staff and other national experts.

“This award is a big win for young people. They will benefit from significant career development opportunities made possible by this grant,” says Mayor Sylvester Turner in a news release. “These are children who would otherwise go without, now having experiences and connections they never thought possible. I commend the National League of Cities for their continued commitment to the future leaders of this country.”

According to the release, the grant money will support the Hire Houston Youth program by connecting diverse opportunity youth to the unique STEM and technology-focused workforce development.

"Our youth deserve educational opportunities that connect them to the local workforce and career exploration, so they can make informed choices about their future career path in Houston’s dynamic economy. Houston youth will only further the amazing things they will accomplish, thanks to this grant," says Olivera Jankovska, director of the Mayor's Office of Education.

Need a job in STEM? You've come to the right place. Photo by Scott Halleran/Getty Images

Houston named the No. 2 city for STEM jobs

Lab work

Sure, Houston can boast that it's the Energy Capital of the World. That's undisputed. However, Houston also is making strides in the wider range of STEM fields — science, technology, engineering, and mathematics.

A new study from the American Enterprise Institute's Housing Center finds Houston is No. 2 among the best U.S. metro areas for STEM workers. Dallas-Fort Worth topped the ranking, and Austin earned the No. 4 spot.

The American Enterprise Institute sifted through data in three categories — STEM employment in 2018, overall employment growth since 1990, and affordability for first-time homebuyers — to devise its ranking. In all, the institute examined the 30 metro areas with the most STEM jobs.

Houston landed at:

  • No. 10 for STEM employment, with 207,000 jobs in 2018. (The Greater Houston Partnership puts the current figure at more than 240,000).
  • No. 6 for overall employment growth (70 percent) since 1990.
  • No. 6 for median home price for first-time buyers.

The study notes that the vibrancy of home construction helped Houston maintain a high rate of employment growth and a high score for home affordability.

"On one hand, some metro areas with relatively high home prices are desirable places to live in terms of jobs and local amenities," the study says. "On the other hand, house prices may be higher than they really need to be due to local policies that needlessly drive up the price of land and thereby constrain the amount of new housing. Households should be aware of these tradeoffs."

Houston fared better in the American Enterprise Institute study than it did in a recent STEM ranking from personal finance website WalletHub. To determine the best markets for STEM professionals, WalletHub compared the 100 largest metro areas across 20 key metrics. Houston ranked 33rd, while Dallas-Fort Worth ranked 38th and Austin came in at No. 4.

Whether Houston stands at No. 2 or No. 33, business leaders are confident the region is fertile territory for STEM.

"Houston's talent base of 300,000 educated millennials and more than 240,000 STEM workers power our leading industries, including life sciences, energy, and manufacturing and logistics," says Susan Davenport, senior vice president of economic development at the Greater Houston Partnership.

"For us to continue to compete and grow in these critical sectors," Davenport adds, "we need to continue to foster and attract new STEM talent and market the positive attributes that make Houston a great place to live."

The Greater Houston Partnership touts several strengths that will propel the region's STEM sector, including:

  • The Texas Medical Center's recently announced TMC3 research hub.
  • A firm foothold in the life sciences industry, thanks to the Texas Medical Center, the world's largest complex of healthcare and life science institutions.
  • NASA's Johnson Space Center.
  • A cluster of more than 6,000 manufacturers.

Davenport points to establishment of Houston's four-mile-long Innovation Corridor — featuring an array of startup accelerators and tech incubators — as another vehicle for STEM success. At the heart of the corridor will be Rice University's new $100 million innovation hub, known as The Ion.

The corridor, she says, "will help Houston create the next generation of companies solving big problems."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."