Three Houston companies are among the best startups for employees. 10'000 Hours/Getty Images

Three businesses based in the Houston area appear in Forbes magazine's inaugural ranking of the best startup employers.

Forbes teamed up with market research company Statista to identify up-and-coming companies that are liked most by those who work there. Researchers evaluated 2,500 U.S. businesses with 50 or more employees on three criteria: employer reputation, employee satisfaction, and growth. The result: Forbes' first-ever ranking, released March 10, of the country's 500 best startup employers.

To create the ranking, Statista looked at articles, blogs, and social media posts about each employer; employee reviews on job websites like Glassdoor and Indeed; and website traffic and employee headcounts for each startup over a two-year span.

The three Houston-area startups that are ranked are: Houston-based 2nd.MD (No. 280), Pearland-based Code Ninjas (No. 350), and Houston-based Onit (No. 463).

San Francisco-based footwear retailer Allbirds snags the No. 1 ranking on the Forbes list, and the Dallas-Fort Worth leads Texas metro areas for the most startups on the list with its 13 startup companies.

Ranked 25th, the highest in Texas, Fort Worth-based Koddi garners the top ranking among all Texas startups. The company provides marketing software for advertisers in the travel industry. In 2019, the Digiday Worklife Awards program named Koddi the tech company with the most collaborative culture.

"Koddi gives its employees the ability to shape the direction of their own careers and empowers them to succeed," Zachary Rector, associate director of account services, said in a 2017 release. "Every day at Koddi offers a unique challenge to overcome and the opportunity for personal growth. All of your coworkers are fully committed to one another's success and help each other learn. Koddi is a fast-paced, ever-changing, and engaging place to work."

Here are the 12 other Dallas-Fort Worth startups that appear in the Forbes ranking:

  • No. 50 — Bestow, Dallas
  • No. 59 — Veryable, Dallas
  • No. 118 — Sector 5 Digital, Fort Worth
  • No. 149 — Stryve Biltong, Plano
  • No. 231 — PestRoutes, McKinney
  • No. 265 — Titus Industrial, Dallas
  • No. 275 — Student Success Agency
  • No. 271 — Meritize, Frisco
  • No. 272 — Defi Solutions, Westlake
  • No. 305 — Crystal Clear Concepts, Grand Prairie
  • No. 325 — WellKept, Arlington
  • No. 411 — Tap Water Watch, Dallas

Meanwhile, Austin had a dozen startups on the list. At No. 87, Austin-based SchooX is the top-ranked startup in the Central Texas region. The company provides a workplace learning platform.

"Working at SchooX provides an awesome environment with great people that changes the way people learn," employee George Litos says on the company's website. "SchooX is shaping the future of e-learning, and I'm proud to be a part of it."

Here are the 11 other Austin-area companies that claim spots in the top 500:

  • No. 97 — Iris Telehealth, Austin
  • No. 201 — Jungle Scout, Austin
  • No. 226 — RigUp, Austin
  • No. 301 — TrustRadius, Austin
  • No. 315 — Shipwell, Austin
  • No. 399 — AlertMedia, Austin
  • No. 430 — Everlywell, Austin
  • No. 451 — Innovetive Petcare, Cedar Park
  • No. 457 — SubjectWell, Austin
  • No. 463 — ScaleFactor, Austin
  • No. 478 — Outdoorsy, Austin
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This article originally ran on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.