2 Houston startups make strategic hires

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Two Houstonians have been named to the C-suites of growing startups. Photos courtesy

A pair of Houston tech startups have recently announced new appointments to their leadership staff. A digital supply chain commerce company named a new CFO, while an Irish health tech company has named its new Houston-based leader.

GoExpedi names new CFO

Jorge Ordonez is the newly named CFO for GoExpedi. Photo courtesy of GoExpedi

Houston-based GoExpedi, an innovative end-to-end digital supply chain and data analytics solutions company, named Jorge Ordonez as CFO for the company.

"With our rapidly accelerating growth, ongoing investment activity and new industrial customers coming online, it was crucial that we bring on board an experienced financial leader who can help us successfully scale at a fast pace," says Tim Neal, GoExpedi CEO, in a news release. "Jorge led one of the top medical equipment providers in the country as well as a leading industrial technology solutions provider. We'll greatly benefit from his diverse financial experience, helping us to become the leading digital industrial supply chain and data analytics providers in North America."

Ordonez brings 25 years of finance and accounting experience across industries, including 10 years in distribution and logistics. His most recent position was CFO at US Med-Equip, a medical equipment provider.

"I am honored to join GoExpedi, one of the most innovative industrial supply chain and data solutions providers out there, at this time of rapid growth," says Ordonez in the release. "I look forward to working closely with GoExpedi's leadership team to support sustained financial success as the company expands into different geographies and sectors. My goals are to help the company continue its financial success and build optimized financial decision-making models and processes that will equip the company to scale and expand capital availability to continue its growth trajectory."

Health tech startup with US operations in Houston names new CEO

Benjamin A. Hertzog will lead Intelligent Implants through its next phase of development. Photo courtesy of Intelligent Implants

Benjamin A. Hertzog, entrepreneur in residence at Johnson and Johnson’s Center for Device Innovation at the Texas Medical Center, has a new title. Last month, Hertzog was named CEO of Intelligent Implants, a development-stage digital medicine and orthopedics startup based in Ireland with its United States operations based in Houston.

“Ben joined Intelligent Implants as Executive Chairman of the Board in 2020, and his broad experience in complex Class-III medical devices, leadership, and exceptional track record made it an obvious choice to have Ben join us at the helm of the company,” says John Zellmer, Intelligent Implants co-founder and founding CEO, in a news release. “Ben has the skills and credibility to guide Intelligent Implants as we navigate through the next stage of clinical and commercial activities. We look forward to his leadership as we continue to achieve key milestones.”

Zellmer will transition into the role of COO while Hertzog is tasked with leading product development, as well as clinical, and commercial activities for the company’s novel and proprietary smart orthopedic implant platform.

With more than 20 years of experience in healthcare and life sciences as an engineer, investor, and entrepreneur, Hertzog has founded medical device startup, Procyrion, leading the cardiac device company through Series C financing, product development, animal studies, strategic investment, and human clinical trials. He also served as managing director of AlphaDev (now Fannin Partners), an early-stage venture development firm.

“I am thrilled to work with John and the entire Intelligent Implants team as we make progress towards bringing this novel technology platform to the market,” says Hertzog. “Throughout my career, I’ve been driven by and focused on bringing innovative medical device therapies to the market, and I believe that SmartFuse represents the future of medical devices; smart connected implants that provide therapeutic benefits and real-time data to support clinical decision making. Ultimately, I believe these implants will have significant advantages to traditional implants in addressing unmet clinical needs and improving patient outcomes.”

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Houston biotech company tests hard-to-fight cancer therapeutics

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A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

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This story originally appeared on our sister site, EnergyCapitalHTX.