The first crew of all civilians is headed into orbit this month — and they are going to bring back essential research. Photo via inspiration4.com

The world's first all-civilian human spaceflight mission to orbit will be participating in health-related research projects sponsored by a Houston organization.

The crew of Inspiration4 will contribute to research projects that the Translational Research Institute for Space Health, or TRISH, at Baylor College of Medicine will sponsor. The project is a collaboration is between TRISH, SpaceX, and investigators at Weill Cornell Medicine.

"The crew of Inspiration4 is eager to use our mission to help make a better future for those who will launch in the years and decades to come," says Jared Isaacman, commander of the Inspiration4 mission, in a news release. "In all of human history, fewer than 600 humans have reached space. We are proud that our flight will help influence all those who will travel after us and look forward to seeing how this mission will help shape the beginning of a new era for space exploration."

According to the release, all biomedical data collected for the Inspiration4 mission will be accessible through an open data repository funded and overseen by TRISH. The mission will include the following TRISH-sponsored research:

  • Collect research-grade ECG activity, movement, sleep, heart rate and rhythm, blood oxygen saturation, cabin noise and light intensity.
  • Perform a series of tests in the Cognition app designed to assess changes in behavioral and cognitive performance. This is the same app that is currently used by astronauts in NASA-funded research studies.
  • Scan organ systems via a Butterfly IQ+ Ultrasound device, which is designed with artificial intelligence guidance for non-medical experts. Data collected will determine if non-medical experts can self-acquire clinical grade images without guidance from ground support and will provide a timeline of biological changes before and during spaceflight. This device is also currently being tested by astronauts on the International Space Station.
  • Collect and test drops of blood during spaceflight for markers of immune function and inflammation using a state-of-the-art miniaturized device called the Vertical Flow Immunoassay.
  • Use balance and perception tests pre-flight and immediately post-flight to measure sensorimotor adaptation during changes of gravity. These tests are currently performed by astronauts upon return from spaceflight.
  • Archive, fully analyze, and share resulting biomedical samples and data in collaboration with investigators at Weill Cornell Medicine and research data in an open format database to enable greater collaborative research.

Researchers at Weill Cornell Medicine will be collecting the environmental and biomedical data and biological samples from Inspiration4's four crew members before, during, and after the mission. These samples and data will be added to a planned Biobank that will hold cryogenically-frozen samples and data from the Inspiration4 mission. The sample collection will enable long-term research and health monitoring for astronauts. WorldQuant is providing funding support for the work at Weill Cornell Medicine.

The mission, which will be aboard SpaceX's Falcon 9, is slated for September 15 from Launch Complex 39A at NASA's Kennedy Space Center. The three-day mission will target approximately a 575 km orbit, flying farther from Earth than any human spaceflight since the Hubble Space Telescope repair missions. Inspiration4's goal is to inspire humanity and raise money for St. Jude Children's Research Hospital.

The space mission will be riding aboard SpaceX's Falcon 9. Photo via inspiration4.com

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Greentown Labs appoints Houston founder among 4 new board members

All a-board

Greentown Labs, a Massachusetts-based climatetech startup incubator with its secondary location in Houston, has appointed four new board members.

Of the new appointees, two community board members have been named in order to act as liaisons between startups and Greentown Labs. Greentown Houston's appointed representation is Nisha Desai, founder and CEO of Intention, and community member. The other new board members are Gilda A. Barabino, president of Olin College of Engineering and professor of biomedical and chemical engineering; Nidhi Thakar, senior director of resource and regulatory strategy and external engagement for Portland General Electric; and Leah Ellis, co-founder and CEO of Sublime Systems, who is the Sommerville location's community board member).

"It is important for a startup incubator to have leadership and insight from stakeholders including the public and private sector, academic and university communities," says Greentown Labs CEO Dr. Emily Reichert in a news release. "These leaders bring a wealth of knowledge relevant to not only climatetech but to our continued growth as an organization. Their voices will be important to have at the table as Greentown charts its course for the next decade of climate action."

Desai's current startup, Intention, is climate impact platform for retail investors, and she has previously worked at six energy-related startups including Ridge Energy Storage, Tessera Solar, and ActualSun, where she was co-founder and CEO. She's also worked in a leadership role at NRG Energy and spent several years as a management consultant with the energy practice of Booz Allen Hamilton — now Strategy&, a PWC company.

"I'm honored to join the board of Greentown Labs as a representative of the startup community," she says in the release. "This is a pivotal time for climate and energy transition. I look forward to working with the rest of the board to expand the collective impact of the Greentown Labs ecosystem."

The four new appointees join seven existing board members:

  • Alicia Barton, CEO of FirstLight Power (Board Chair)
  • Katherine Hamilton, Chair of 38 North Solutions
  • Dawn James, Director of US Sustainability Strategy and Environmental Science at Microsoft
  • Matthew Nordan, Co-Founder and Managing Director of Prime Impact Fund and General Partner at Azolla Ventures
  • Kathleen Theoharides, Secretary of Energy and Environmental Affairs, Commonwealth of Massachusetts
  • Mitch Tyson, Principal at Tyson Associates and Co-Founder of the Northeast Clean Energy Council
  • Dr. Emily Reichert, CEO of Greentown Labs

Houston fund makes first local investment in $8M deal

money moves

A Houston-based investment fund has announced its its latest deal that includes an investment into a local direct-to-consumer supplement company.

GP Capital Partners has invested in Qualitas Health, known as iwi, which produces plant-based omega-3 and protein products that's sold directly to consumers as well as retailers across the United States. Iwi's nutrition supplement is sustainably sourced from the company's cultivation pond systems, which are the size of football fields and located in New Mexico and Texas.

“We are excited about our investment in iwi. They have a proprietary and scalable process to create in-demand products in a sustainable manner," says Gina Luna, principal of the fund, in the news release. "We look forward to working with iwi’s management team as they pursue this transformative opportunity.”

The $8 million deal — $5.5 million in senior secured term debt and a $2.5 million direct equity investment — will help iwi accelerate sales of its existing products and ramp up development, marketing, and growth of new protein-based product, according to the release. Iwi will also enter new international markets.

“The iwi team looks forward to working with GP Capital Partners following their investment in our growing company. We have big plans for accelerating our growth, and are pleased to partner with this team that brings both expertise and relationships to support us in this new stage of the company," says Miguel Calatayud, CEO of iwi, in the release.

Outside of GP, the Houston company's other investors include Grupo Indukern, Gullspång Re:food VC, PeakBridge VC, , Arancia Group, Trucent, SASA, and Minrav. GP launched its $275 million fund last year. It's structured as a Small Business Investment Company and will deploy funding into 20 to 25 companies within the Gulf Coast region.

The supplement company is based in Houston. Photo via Instagram

How company behavior guides activists’ choices, according to this Houston researcher

houston voices

It’s been more than 100 years since Pavlov’s dog showed the world that behavior is often guided by forces we don’t comprehend.

The same is true of the interaction between companies and protestors, according to Rice Business professor Alessandro Piazza and Fabrizio Perretti of Bocconi University in Milan. In a recent study, the scholars show that when protestors fight to change a company’s policy, their future choices of where and how much to protest are shaped by the company’s response.

Moreover, the outcome may not be what either group has planned for. Companies that meet protestor demand often inadvertently spur the protestors to demonstrate further; conversely, companies that refuse to give in tend to propel protestors to redirect their energies toward related but different issues.

The researchers based their conclusions on a deep dive into the anti-nuclear movement of the 1970s and 1980s, and a close analysis of protests and company responses in specific locations.

During the time period studied, the researchers found, public sentiment toward nuclear energy changed from mild support to open hostility in the form of an organized protest movement. To quantify this movement’s impact on nuclear power plant construction, the researchers studied the aftermath of protestors’ local victories.

In Massachusetts, for example, the first nuclear power protest in 1974 persuaded Northeast Utilities to postpone, and then permanently cancel, its plant. This reaction, Piazza and Perretti found, catalyzed local protestors. In the years that followed, the region became one of the United States’ strongest bastions of anti-nuclear activism.

In order to quantify how company actions affected protests, the researchers first measured the number of U.S. protest events by geographic location from 1970 to 1995. They then compared this number to the number of nuclear facilities either completed or cancelled over a one-year time period within 100 miles of a given demonstration. They included controls to account for local economic and political differences upon local activism, and for any geographic bias of the newspaper sources used to identify protest events.

The patterns they found were intriguing. Proposing a new plant for construction boosted anti-nuclear protests by 18 percent in a 100-mile radius. Cancelling construction of a plant drove a 27 percent increase in anti-nuclear protests. And when a new nuclear plant was completed and connected to the grid, the researchers witnessed a 2.3 percent increase in the number of protests not directly aimed at nuclear power plants.

The reason for the increase in other protests when a company prevailed and built a power plant? The researchers hypothesize that each time a plant was completed, demoralized activists attached themselves to other movements.

These results raised a related question. Did company decisions on one type of controversy, such as a nuclear power plant, lead to greater support for related protest movements or for unrelated ones? The former, it turns out.

To measure this, the researchers again looked at protests within given regions and categorized them into anti-nuclear weapon protests, environmental protests, public policy protests, anti-war protests and protests against the proximity of a given plant to a specific property, that is, “not in my backyard” protests.

Nuclear power opponents, they found, were most likely to turn to adjacent issues such as protests against nuclear weapons. Protest activities, in other words, have a domino effect.

While most research tracks the effects of activism on companies, Piazza and Perretti’s study shows that the way companies act is also a critical event driver. Company choices can actually drive the evolution of activism, triggering activist mobilization in other causes.

The research represents a challenge to traditional explanations of activism, which usually assume that mobilization and protests are most effective early on then dwindle over time, regardless of the behavior of the organization.

Piazza and Perretti’s findings suggest a valuable lesson for companies, especially those operating in more than one location: Their decisions in one place may actually escalate activism elsewhere. Pacific Gas & Electric successfully acted on this insight in the 1980s. Working with the Sierra Club, the company swapped the cancellation of one site at Bodega Bay, California — the target of frequent protests — for support of a plant at a second site elsewhere in the state at Diablo Canyon.

The findings also offer important insight for activists choosing a company on which to focus. These activists should keep in mind that the companies most likely to capitulate are also the ones most likely to feed a movement going forward — providing, in effect, the possibility of a double win.

Meanwhile, even if they fail in one effort, activists can take heart that their energy isn’t necessarily wasted. Only a little further afield, a similar movement may gain momentum from demoralized protestors looking for a new cause.

------

This article originally ran on Rice Business Wisdom and is based on research from Alessandro Piazza, an assistant professor of strategic management at Jones Graduate School of Business at Rice University.