For years, Squid Compression has helped ease the pain of patients in doctor's offices. Now, anyone can get the treatment on the go. Photo via squidgo.com

Houston company creates portable device that eases pain without the use of drugs

No pain, just gain

Many of the estimated 50 million Americans who suffer from chronic pain turn to drugs — including heavily abused opioids — to relieve their symptoms. Houston-based startup Portable Therapeutix LLC's drug-free solution to pain management seeks to put a dent in the market for prescription painkillers.

In 2018, Houston-based Portable Therapeutix introduced Squid Go, a portable device that's designed to ease the pain and swelling of sore joints and muscles. It's a follow-up to the company's Squid Compression, a pain management device launched in 2013 for patients at rehabilitation centers, hospitals, doctor's offices, and the like.

Squid Go enables consumers to apply two approaches — cold therapy and compression therapy — to relieving joint pain and swelling caused by arthritis, bouncing back from athletic activities, or recovering from an injury or surgery involving muscles and joints. Variations of the device can treat ankle, back, leg, knee, shoulder, or wrist pain.

To reap the benefits of Squid Go, a consumer uses the device for just 15 minutes. Squid Go — which combines a cold gel pack with proprietary compression technology — features special air pockets that inflate and deflate, gently massaging the body part needing treatment. That massaging boosts circulation and reduces swelling.

"Increased circulation brings more nutrient- and oxygen-rich blood to the area, promoting recovery," says Sam Stolbun, co-founder of Portable Therapeutix. "Meanwhile, [the] gentle compression also drives the pain-relieving cold from the gel pack deeper into the tissues to alleviate soreness and discomfort."

The coldness of the gel pack fights inflammation.

Stolbun says someone can take the lightweight, portable Squid Go device to the office, to the gym or anywhere else for on-the-go pain relief. It even can be used without the cold gel pack for compression-only therapy to improve circulation and decrease swelling. The Squid Go pump delivers about 15 treatments before it needs to be recharged.

Squid Compression received clearance from the U.S. Food and Drug Administration as a prescription-only device in 2013 and gained over-the-counter status in 2014. The consumer version, Squid Go, employs the same technology and operates the same way as Squid Compression, so a second FDA stamp of approval wasn't required.

Pricing for the heavy-duty Squid Compression system starts at $700. The consumer-friendly Squid Go system goes for $300 or $350, depending on its purpose. Users can buy extra wraps and gel packs to supplement the system.

Stolbun says he and co-founder Shai Schubert developed the Squid devices after realizing that existing pain-fighting cold packs provided only superficial relief, while water-based treatments were inconvenient and offered no compression advantages. Still other cold and compression therapies on the market are expensive and generally aren't covered by health insurance, he says.

Stolbun says that "it became apparent that a reasonably priced, well-made, portable, and effective pain relief and recovery device would meet a need for a broad range of consumers — from athletes to seniors."

Stolbun, a sports enthusiast and bakery mogul, and Schubert, a scientist and entrepreneur, established Portable Therapeutix in 2011.

The company's debut product, Squid Compression, still enjoys success, but Stolbun says the company has shifted its focus to Squid Go. Portable Therapeutix plans to pump up sales for Squid Go via its online presence, he says, as well as through physical therapists, sports trainers and other professionals who've used Squid Compression but want to offer the less pricey Squid Go model to their clients for in-home treatment.

Portable Therapeutix is backed by private investors; the amount of funding it has received isn't available. The company doesn't release revenue and profit figures.

Today, the company employs just one person in Houston but will add workers as its distribution pipeline expands, Stolbun says. Sales, marketing, and customer service representatives are scattered around the country. Stolbun, the CEO, is based in Houston, while Schubert, the chief technical officer, is based in Boston.

Portable Therapeutix relies, in part, on word-of-mouth praise to promote Squid Go. Among those hailing the device is Lee Ward of Houston, who describes himself as a competitive tennis player.

On the Squid Go website, Ward explains that he'd been suffering from progressively worsening tendonitis in his knees for a couple of years.

"I tried a number of remedies, including ice and gel packs, immediately following my tennis workout, but both remedies were ineffective and difficult to use," Ward says in his online testimonial.

He then discovered Squid Go and became a fan.

"The best thing about [Squid Go] is its ease of use. It provides a quick, effective treatment that makes it ideal for daily use by both the serious and recreational athlete," Ward says.

Smart tech

Courtesy of Squid Go

Squid Go combines a cold gel pack with proprietary compression technology and features special air pockets that inflate and deflate, gently massaging the body part needing treatment.

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Rice University announces leader of new materials and nanotechnology institute

at the helm

A recently established institute at Rice University has revealed its new leader.

The Rice Advanced Materials Institute has named Lane Martin as director. Martin will also serve as Welch Professor of Materials Science and NanoEngineering in the George R. Brown School of Engineering. He begins both roles on July 1.

“Lane is everything we expect our faculty to be — hard-working, committed to excellence, dedicated to students and collaborative across disciplines,” says Howard R. Hughes Provost Amy Dittmar in a news release. “I look forward to seeing Rice faculty and students reap the benefits of his leadership.”

Prior to his appointment at Rice, Martin was the chancellor’s professor of materials science and engineering at the University of California, Berkeley. He also served as chair of the materials science and engineering department, faculty scientist in the material sciences division of the Lawrence Berkeley National Laboratory, and co-director of the Collaborative for Hierarchical Agile and Responsive Materials, according to the release.

“I had the privilege of mentoring Lane when he was a doctoral student at Berkeley,” says Ramamoorthy Ramesh, vice president for research, professor of materials science and nanoengineering and professor of physics and astronomy. “He is a gifted scientist with the boldness and vision to build this new institute into a research powerhouse.”

The new institute was created following a $100 million gift from Houston-based Welch Foundation. It will bring together chemistry, materials science, machine learning, and artificial intelligence to revolutionize the future of industry.

“This institute will keep Rice at the forefront of high-impact research related to energy transition, advanced materials and future computing,” says Luay Nakhleh, the William and Stephanie Sick Dean of the school, in the release. “It will empower our faculty and students to help solve some of the most pressing problems of our day.”

Report: Texas rises through the ranks of most innovative states

moving on up

The Lone Star State has again taken a step up on an annual report that ranks the most and least innovative states in the country — this time cracking the top 15.

Texas ranked No. 15 in personal finance site WalletHub's 2023’s Most and Least Innovative States ranking. It's a steady improvement for the state, which ranked No. 16 in 2022 and No. 17 in 2021.

The report analyzed the 50 states and the District of Columbia and how each performed across 22 key metrics, including population of STEM professionals, venture capital investment activity, number of technology companies, patents per capita, and more. The data was pulled from the U.S. Census Bureau, Bureau of Labor Statistics, National Science Foundation, National Center for Education Statistics, United States Patent and Trademark Office, and other records.

Here's how Texas performed at a glance:

  • No. 18 for share of STEM professionals
  • No. 16 for projected STEM job demand by 2030
  • No. 25 for eighth grade math and science performance
  • No. 21 – for share of science and engineering graduates aged 25 or older
  • No. 13 – for share of technology companies
  • No. 31 – for R&D spending per capita
  • No. 18 – venture capital funding per capita
For the 11th year, Texas won Site Selection Magazine's Governor's Cup, the governor's office announced earlier this year. The award, which Texas has won 19 times since its inception in 1978, recognizes the nation’s top-performing state for job-creating business relocations and expansions.

"Texas truly is America’s economic engine, and we stand apart as a model for the nation. When choosing where to relocate or expand their businesses, more and more innovative industry leaders find themselves at home in our state," Governor Greg Abbott says in a news release about the award.

"I congratulate the exceptional economic development teams at the local, regional, and state level who have worked so diligently to attract and retain these growing businesses and the jobs they create in diverse communities across this great state," he continues.

The most innovative states included the District of Columbia, which ranked at No. 1, followed by Massachusetts, Washington, Maryland, and California, respectively. The least innovative state was identified as Mississippi, followed by Louisiana, North Dakota, West Virginia, and Arkansas, respectively.

Source: WalletHub

Access to quality education is a significant contributor to each state's innovation economy, the experts say in the report.

"Investing in education, particularly K-12 but also at the University level, it is no accident that innovative ecosystems develop in states with strong education systems and research universities," says David L. Deeds, professor at the University of St. Thomas in Minneapolis. "These institutions build strong capable modern workforces that attract capital, and jobs and create innovations. The benefits do not happen overnight, in fact, they take years if not decades, but consider what The UC’s or the University of Texas at Austin have meant for the development of premier innovative ecosystems."

Investor advocates now is the time to position Houston as a leading biomanufacturing hub

houston innovators podcast episode 178

Houston has all the ingredients to be a successful synthetic biology hub, says Veronica Wu. She believes so strongly in this that she relocated to Houston from Silicon Valley just over a year ago to start a venture capital firm dedicated to the field. Since then, she's doubled down on her passion for Houston leading in biotech — especially when it comes to one uniquely Houston opportunity: biomanufacturing.

While Houston's health care innovation scene is actively deploying synthetic biology applications, Wu points to Houston-based Solugen, a plant-based chemical producer, as an example of what Houston has to offer at-scale industrial biomanufacturing. Houston has the workforce and the physical space available for more of these types of biomanufacturing plants, which have a huge potential to move the needle on reducing carbon emissions.

"This is really fundamental technology that's going to change the paradigm and whole dialogue of how we are making a significant impact in reducing a carbon footprint and improving sustainability," says Wu, founder and managing partner of First Bight Ventures, on the Houston Innovators Podcast.

Several aspects — government funding, corporate interest, advances in technology — have converged to make it an ideal time for synthetic biology innovators and investors, Wu explains on the show, and she has an idea of what Houston needs to secure its spot as a leader in the space: The BioWell.

First introduced at a Houston Tech Rodeo event at the Texas Medical Center's Innovation Factory, The BioWell is a public-private partnership that aims to provide access to pilot and lab space, mentorship and programming, and more support that biomanufacturing innovators critically need.

"The way we envision The BioWell is it will provide a holistic, curated support for startups to be able to get across the Valley of Death," Wu says, explaining that startups transitioning from research and development into commercialization need extra support. The BioWell will provide that, as well as allow more engagement from corporations, investors, and other players.

Now that her plans for The BioWell have been announced, Wu is looking for those who want to be a part of it.

She shares more about her mission and what's next for First Bight Ventures on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.