Prada is collaborating with Houston-based aerospace company Axiom Space on the design of spacesuits for NASA’s Artemis III mission to the moon. Photo via axiomspace.com

Courtesy of the Prada luxury brand, NASA astronauts are getting an infusion of fashion.

Prada is collaborating with Houston-based aerospace company Axiom Space on the design of spacesuits for NASA’s Artemis III mission to the moon. Astronauts haven’t yet been chosen for the mission, which is set for 2025.

“Prada’s technical expertise with raw materials, manufacturing techniques, and innovative design concepts will bring advanced technologies instrumental in ensuring not only the comfort of astronauts on the lunar surface, but also the much-needed human factors considerations absent from legacy spacesuits,” says Michael Suffredini, co-founder, president, and CEO of Axiom Space.

The spacesuit, called the Axiom Extravehicular Mobility Unit (AxEMU), is geared toward improving astronauts’ flexibility, boosting protection against harsh conditions, and supplying tools for exploration and scientific activities.

“Our decades of experimentation, cutting-edge technology, and design know-how – which started back in the ’90s with Luna Rossa challenging for the America’s Cup – will now be applied to the design of a spacesuit for the Artemis era. It is a true celebration of the power of human creativity and innovation to advance civilization,” says Lorenzo Bertelli, marketing director of the Prada brand.

NASA has enlisted Axiom and Charlotte, North Carolina-based Collins Aerospace to outfit astronauts with next-generation spacesuits. Axiom’s partners on this project are KBR and Sophic Synergistics, both based in Houston, along with Air-Lock, A-P-T Research, Arrow Science and Technology, David Clark Co., and Paragon Space Development.

Collins maintains a sizable presence at the Houston Spaceport.

In July, Axiom secured a NASA task order potentially worth $147 million to modify the Artemis III spacesuit for astronauts heading to the International Space Station. This follows a $228 million NASA task order awarded to Axiom in 2022 for development of the Artemis III spacesuit.

The task orders are part of Axiom’s $1.26 billion spacesuit contract with NASA. All told, NASA has earmarked as much as $3.5 billion for new spacesuits.

For its return to the moon, NASA has doubled down on its relationships with two companies in Houston. Photo courtesy of NASA

NASA expands spacesuit partnerships with 2 Houston tech companies in $5M deals

getting ready to moon walk

Two Houston space tech companies are suiting up thanks to an expanded relationship with NASA.

Axiom Space and Collins Aerospace, which have been working with NASA developing new spacesuits since last summer, have each received $5 million to continue their work. The new spacesuits will be used in NASA's upcoming Artemis missions. Axiom Space, which unveiled its design in March, is creating a suit that will be used in low Earth orbit, and Collins Aerospace, headquartered in Charlotte, North Carolina, but with a significant presence in Houston, will build a suit that will be worn on the lunar surface.

“These task orders position NASA for success should additional capabilities become necessary or advantageous to NASA’s missions as the agency paves the way for deep space exploration and commercialization of low Earth orbit,” says Lara Kearney, manager of the Extravehicular Activity and Human Surface Mobility Program at the Johnson Space Center, in a news release. “Using this competitive approach we will enhance redundancy, expand future capabilities, and further invest in the space economy.”

The spacesuit, revealed in March, will be worn by the first woman and first person of color to visit the moon. Photo courtesy of Axiom Space

These two new Exploration Extravehicular Activity Services task orders are being issued due to an increased capability request.

"Axiom Space was previously awarded an initial task order to develop a spacewalking system for a demonstration in partial gravity on the lunar surface during Artemis III and will now begin early assessments for extending that suit for use outside the International Space Station," reads the NASA news release. "Likewise, Collins Aerospace was previously awarded an initial task order to develop a spacewalking system for a demonstration in microgravity outside the space station and will now begin early assessments for extending that suit for use on the lunar surface."

Each part of the missions — low Earth orbit and the lunar surface — come with their own set of challenges, including variation in gravitational fields, environments, and mission tasks. These suits will potentially be used throughout the lunar missions through 2034.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."