10 can't-miss events from Houston-based SpaceCom's virtual conference

where to be online

SpaceCom is taking place online this year for free. Here's what you need to sign up for. Photo courtesy of SpaceCom

Today marks the first day in SpaceCom's two-week online conference featuring space entrepreneurs, NASA executives, government experts, and more.

Usually a must-attend event hosted at George R. Brown Convention Center in downtown Houston, SpaceCom is free and virtual this year. Register to attend and check out this curated list of 10 can't-miss discussions.

Click here for the full schedule. (All times have been updated to reflect CDT times)

Tuesday, October 20 — General Session: Whole of Government

Greg Autry, director at SoCal Commercial Spaceflight Initiative, will moderate a discussion with Kevin O'Connell, director at the Office of Space Commerce Department of Commerce, and Scott Pace, executive secretary at the National Space Council. The panel will discuss how they will work together on policies and actions they need to take to enable the trillion-dollar space economy.

This virtual panel takes place online on Tuesday, October 20, from 10 to 10:45 am. Learn more.

Tuesday, October 20 — Carbon Footprint and Emissions Monitoring

Satellite data can give governments and industry the ability to monitor and reduce the carbon footprint. In this panel, experts will discuss the companies that operate and use satellite data to monitor, manage and profit from satellites that monitor the planet's carbon footprint.

  • Lou Zacharilla, director of Innovation Space & Satellite Professionals International (moderator)
  • Sebastien Biraud, staff scientist and Climate Sciences Department Head at Lawrence Berkeley National Laboratory
  • Steve Hamburg, chief scientist at the Environmental Defense Fund
  • Yotam Ariel, CEO of Bluefield Technologies
This virtual panel takes place online on Tuesday, October 20, from 12 to 12:45 pm. Learn more.

Thursday, October 22 — Keynote: Industry Applications

This general session features how Amazon Web Services helps terrestrial industries take advantage of space enabled services already in place at competitive pricing. Speaker Clint Crosier from Amazon Web Services and moderator Douglas Terrier, chief technology officer at NASA.

This virtual panel takes place online on Thursday, October 22, from 10 to 10:45 am. Learn more.

Monday, October 26 — Keynote: International Space Station

The new head of NASA's International Space Station program, Joel Montalbano, who is based in Houston's Johnson Space Center, provides a status of and exciting new industry applications for the ISS as well as insight into the future of ISS.

This virtual panel takes place online on Monday, October 26, from 10 to 10:45 am. Learn more.

Monday, October 26 — NASA Session: Transferring NASA Technology

NASA's treasure trove of technology is available to American industry and entrepreneurs to apply in profitable ways. In this session, NASA technology transfer leaders — Daniel Lockney, Kimberly Minafra, and Krista Jensen — will discuss the many ways the private sector can tap into the accumulated knowledge NASA has to share.

This virtual panel takes place online on Monday, October 26, from 11 to 11:45 am. Learn more.

Tuesday, October 27 — Space Tourism: The Excitement and Expectations

A panel of industry experts will discuss the space tourism industry, taking a deep dive into what the future holds, constraints for the industry's ability to address the market for many years to come and how some of these projects will be executed from a business, technology and execution perspective.

  • Amir Blachman, chief business officer of Houston-based Axiom Space
  • Jane Poynter, founder and co-CEO of Space Perspective
  • Sudhir Pai, CEO of Autonomous Energy Ventures
  • Richard Garriott, private astronaut (moderator)

This virtual panel takes place online on Tuesday, October 27, from 11 to 11:45 am. Learn more.

Tuesday, October 27 — Spaceports as the Innovation Hub for Regions

Spaceports around the world can, and in many cases are, serving as regional innovation centers for high tech activities and creating positive economic development opportunities. Speakers Cherie Matthew, project manager at Corgan, and Pam Underwood, director at the FAA Office of Spaceports, review what the future looks like for spaceports and what funding will be necessary with moderator George Nield, president of Commercial Space Technologies LLC.

This virtual panel takes place online on Tuesday, October 27, from 12 to 12:45 pm. Learn more.

Wednesday, October 28 — NASA Session: Industries of the Future

NASA technology is creating the underpinning for new industries of the future. NASA's work has already changed the world with advances in telecom and microprocessors. More is yet to come. This panel led by Douglas Terrier, NASA chief technologist will explore the industries on the horizon that will stem from NASA innovation.

This virtual panel takes place online on Wednesday, October 28, from 11 to 11:45 am. Learn more.

Thursday, October 29 — Keynote: Women of Space

NASA's head of human exploration, Kathy Lueders, based in Houston's Johnson Space Center, discusses the crucial role that women have, are, and will continue to provide in getting America back to the Moon, as well as in creating the trillion-dollar commercial space economy with moderator Vanessa Wyche, deputy director at JSC.

This virtual panel takes place online on Thursday, October 29, from 10 to 10:45 am. Learn more.

Thursday, October 29 — Zoom to the Moon

An international panel discussion with Orion Program Managers about progress toward launching NASA's first human-rated spacecraft to travel around the Moon since 1972.

  • Catherine Koerner, NASA Orion Program Manager NASA at JSC
  • Didier Radola, head of ORION ESM Programme Airbus
  • Nico Dettman, Lunar Exploration Group Leader for Lunar Exploration Development Projects European Space Agency
  • Tony Antonelli, Artemis II mission director Lockheed Martin

This virtual panel takes place online on Thursday, October 29, from 12 to 12:45 pm. Learn more.

The panel of experts discussed the Space City's history — but also its future as a leader in space exploration. Photo courtesy of SpaceCom

Overheard: Houston experts weigh in on the future of the Space City

EAVESDROPPING IN HOUSTON

Houston's been known as the Space City for about 50 years since "Houston" was the first word spoken from the surface of the moon. But whether or not that nickname will continue to stick was up for debate at a 2019 SpaceCom panel on November 21.

The panel, entitled "Regional Benefits of a Commercial Space Economy: Case Study Houston," the panelists set out to discuss the city's rich history of space exploration, as well as to answer the question of where Houston's space industry is headed.

"We could ask that question in a passive way, but my preference is that here in Houston we ask the question now, answer it, and be very proactive and deliberate about making sure we get the outcome that we want," says Vernon McDonald, senior vice president at KBR and moderator of the discussion.

If you missed the enlightening discussion, here are a few takeaways from the panelists.

"Houston is in this great position to be this beacon to lead entrepreneurs and inspire other regions to explore further."

— Rick Jenet, director of the Center for Advanced Radio Astronomy. Jenet, who is based in Brownsville, Texas, is working to develop a vibrant commercial space hub in South Texas. In a lot of ways, the area looks to Houston's history for its development, he says.

"We built a community of engineers and scientists and a workforce that's all vested in the outcome of the human space flight program."

— Steve Altemus, president and CEO of Intuitive Machines. The creation of the Johnson Space Center developed generations within the community of scientists and engineers, but, moving forward, Houston has to be intentional about building its talent base. "I'm very passionate about doing that here in Houston," Altemus adds.

"There's a beacon of hope for our community if we can organize around it and attract commercial business here to keep this city the Space City, but redefine ourselves as a commercial space hub."

— Altemus says, adding that it's going to take further development, talent, and funds — like what's happening at the Houston Spaceport — to make this transition.

"Over the years, Houston took space for granted. Houston started to focus on the bigger industries that brought in funding and jobs."

— Steven Gonzalez, technology transfer strategist at NASA's Johnson Space Center. At the risk of being unpopular, Gonzalez mentions that the city's attention has been diverted from space exploration. However, he adds, there are new initiatives from the Greater Houston Partnership and Houston First that are picking up the slack.

"The answers to Houston delivering on its potential is going to be collaborations — how well we collaborate."

— Harvin Moore, president at Houston Exponential. Houston is collaborative, and the city needs to make sure its resources are inclusive as commercial space develops in town.

"I'd like to say that Houston is the birthplace of human space flight, and in 50 years, I'd like to see the city be the leader and the point of the spirit for human exploration internationally and commercially out in mars and beyond.

— Altemus responds when asked about the Space City's next 50 years.

"I think what Houston will be most proud of in 50 years is that we played an extremely important role in shaping how Texas leads the world in commercial space exploration."

— Jenet, who mentions that there's space exploration innovation happening statewide.

"When you think about what [leading space exploration] company will be here fifty years from now, I don't think it's been created yet. But I would like that company to be here in Houston."

— Gonzalez says, adding that the first trillionaire is likely to make his or her fortune in the space industry, and he wants that money here in Houston.

"A lot of our future is not going to be based on what huge companies or government are doing but much more about entrepreneurs."

— Moore says, emphasizing the need for developing startup resources in Houston.

In his SpaceCom 2019 keynote address, Bill Nye shares the breakthrough technology he's been able to develop at The Planetary Society. Photo courtesy of SpaceCom

Bill Nye shares the future of space exploration at Houston's annual SpaceCom

out of this world

According to Bill Nye, known to most as "The Science Guy" but who now leads the largest non-government space exploration nonprofit, humanity has always asked two questions: How did we get here and are we alone.

"If you want to answer those two questions, you've got to explore space," Nye, CEO of The Planetary Society, says in his keynote address at Houston's annual SpaceCom.

The conference, which took over downtown Houston's George R. Brown Convention Center for November 20 and 21, welcomed a record number of attendees from all over the world. Throughout the two days, 2,500 space fans, experts, and professionals from around the world engaged with panels and programming as well as the exhibit hall full of dozens of space companies.

In his keynote address, Nye walked through the history of solar space studies and breakthroughs, from Johannes Kepler's 17th century observation of the sun's solar force on comets to Carl Sagan's work to develop a completely solar powered spacecraft. Sagan, who was a mentor to Nye, passed away in 1996 and didn't get to see his dream become reality.

Nye, however, has accomplished Sagan's goals, and the technology he and The Planetary Society has developed is low cost and completely citizen funded, representing a huge step toward democratizing space.

"We built two spacecrafts for $7 million," Nye says of LightSail 1 and 2.

The first iteration didn't last long, but LightSail 2 equipped with CubeSats — small but mighty satellites — became the first controlled solar sail spacecraft completely propelled by the sun. Solar sails use radiation pressure from the sun as an energy source reacting with extremely thin reflective material that makes up the sail.

The device, which is still in space, represents a lot of potential for long-term space missions since no fuel is needed. While there have been light sails launched in the past, LightSail 2 was the first iteration to be able to be steered from earth in a timely manner. (The device can be turned in a matter of minutes.)

"With this technology, we can democratize space," Nye tells the crowd, sharing that just a few hours before, Time magazine named the technology as the most innovative invention in aerospace.

Nye says that while the work he is doing at The Planetary Society came about as a group of engineers trying to solve a specific problem, the results they have found and the feedback they received represent the world's interest in continuing space exploration in a cost-effective and feasible way.

"Space brings people together," Nye says.

From enlightening talks and conventions to networking opportunities, here's where you need to be in November. Getty Images

10+ can't-miss Houston business and innovation events for November

Where to be

Looking for some help navigating an innovation-filled month in Houston? Look no further.

November is jam packed with Houston business and innovation events — from huge conventions like SpaceCom and Global Corporate Venture taking over downtown on the same days to the Digital Fight Club battling it out in Houston for the first time and The Houston Innovation Summit planning a week of programming.

If you know of innovation-focused events for this month or next, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

November 5 — Female Founder Luncheon with MassChallenge and HX

Houston is full of entrepreneurial women and this event aims to bring women together and give access to top female entrepreneurs and passionate women in local businesses. They will share their 'why,' their stories, challenges, successes, tips, and answer your burning questions about local entrepreneurship. Join us for a panel and lunch in a closed setting where we discuss what it takes to be a successful female entrepreneur.

Details: The event is from 11 am to 1 pm on Tuesday, November 5, at Houston Exponential (410 Pierce St.). Learn more.

November 6 — Texas Life Science Forum

Rice Alliance's Texas Life Science Forum brings together members from industry, emerging life science companies, academic, and investors. This is the "must attend" event for anyone in the life science industry in Texas or affiliated with innovation at the life science academic institutions.

Details: The event is from 8:30 am to 5 pm on Wednesday, November 6, at BioScience Research Collaborative (6500 Main St.). Learn more.

November 6 — Baker Tilly - Six Figure #Fail

Details: The event is from 11:30 am to 1 pm on Wednesday, November 6, at The Cannon (1336 Brittmoore Road). Learn more.

November 6 — Science First: Changing the Trajectory of Lung Cancer

In honor of Lung Cancer Awareness Month, JLABS sitting down with experts at The Lung Cancer Initiative at Johnson & Johnson and MD Anderson Lung Cancer Moon Shots as well as innovators in the field to present on and create dialogue around the core challenges faced by innovators in the field, new discoveries, emerging technologies, and potential solutions.

Details: The event is from 11 am to 1:30 pm on Wednesday, November 6, at JLabs @ TMC (2450 Holcombe Blvd.). Learn more.

November 7 — TMCx Demo Day: Medical Device 2019

TMCx's annual medical device cohort celebrates the end of another program as the participating entrepreneurs take to the main stage to pitch their solutions. During the event, 16 medical device startups will showcase the progress they have made on their solutions, and what they have planned for the future.

Details: The event is from 1:30 to 8 pm on Thursday, November 7, at TMC Innovation Institute (2450 Holcombe Blvd.). Learn more.

November 8-10 — Second Annual Health Equity Hackathon

CareSet presents the second annual Health Equity Hackathon using newly available data that will help address innovations for the underserved community in the U.S.

Details: The event is from November 8 through 10, at United Way of Greater Houston (50 Waugh Dr.). Learn more.

November 12 — Houston Forum for Equitable Development without Displacement

Rice University is planning to develop 16 acres around Houston's Wheeler Station to create a neighborhood centered around technology, innovation, and entrepreneurship. To demand that the developers sign a Community Benefits Agreement, we are establishing the Houston Coalition for Equitable Development without Displacement (HCEDD). All individuals, community groups, advocacy organizations, and supporting businesses/organizations who are interested in supporting this initiative are invited to attend.

Details: The event is from 6 to 8 pm on Tuesday, November 12, at Wesley AME Church (2209 Emancipation Ave). Learn more.

November 13 — Upstream Venturing + Technology Showcase

In collaboration and partnership with Equinor Technology Ventures, BP Ventures, Shell Ventures, Saudi Aramco Energy Ventures, and Cannon Ventures, hear the latest trends in upstream technology implementation.

Details: The event is from 5 to 8 pm on Wednesday, November 13, at The Cannon (1336 Brittmoore Road). Learn more.

November 14 — TopCoder Innovation Summit

The Topcoder Innovation Summit is the premier innovation event for industry leaders. At the Innovation Summit, you'll have the opportunity to speak with industry leaders, attend panels on innovation and emerging technologies, and meet with the Wipro and Topcoder executive teams.

Details: The event is from 8 am to 4:45 pm on Thursday, November 14, at InterContinental Hotel (6750 Main St.). Learn more.

November 14 — JLABS x UH: Startup Pains: From Academia to Startup (Therapeutics)

JLABS and the University of Houston Technology Bridge present a special installment of Startup Pains, a monthly talk given by entrepreneurs who share their journey of launching a company and overcoming unanticipated obstacles in order to find success in their industry. This month's focus is to arm those contemplating entrepreneurship with a road map for navigating the startup waters, specifically focused on therapeutics.

Details: The event is from 5:30 to 7 pm on Thursday, November 14, at JLabs @ TMC (2450 Holcombe Blvd.). Learn more.

November 15 — Tilting the Grid: How Electricity Companies Will Disrupt

Tilting the Grid is the conference where you can eavesdrop on what the most daring companies in the REP space are doing and discuss what the next "big" thing might be. Ready to learn what big data can reveal about customer behavior? Prepared for a deep dive into the latest customer acquisition trends?

Details: The event is from noon to 5 pm on Friday, November 15, at Whitehall Hotel Houston (1700 Smith St). Learn more.

November 18-24 — The Houston Innovation Summit

For the third year, Houston's innovation ecosystem is taking over the city for a week of events and programming coordinated by Impact Hub Houston. To check out the panels, meetups, and all other programming, click here. Note: Some of the specific events will also appear in this curated list of Houston events.

November 20 — Houston Digital Fight Club

Entrepreneurs and experts are taking the stage — or in this case ring — to battle out their ideas on tech and innovation in Houston. The high energy debate will take place across five fights and networking opportunities. Secure your tickets — it's expected to sell out.

Details: The event is from 6 to 10 pm on Wednesday, November 20, at White Oak Music Hall (2915 N Main St.). Learn more.

November 20 — Inside Billy's Brain: Surgeon, Inventor, Innovator

Join JLABS @ TMC and explore the mind and motivations of Dr. Billy Cohn, the renowned surgeon, inventor and innovator.

Details: The event is from 11:30 am to 1:30 pm on Wednesday, November 20, at JLabs @ TMC (2450 Holcombe Blvd.). Learn more.

November 20-21 — SpaceCom

SpaceCom, America's Commercial Space Conference and Exposition, addresses the strategic issues impacting the commercial space industry that will enable your business to set a clear course to gain a competitive advantage in the coming trillion-dollar space economy. SpaceCom is operating under a Space Act Agreement with NASA. In 2019, the Department of Commerce's Office of Space Commerce and the Department of Energy's Office of Technology Transitions join NASA and the commercial space industry in collaborating on the development of the show.

Details: The event is from Wednesday, November 20, to Thursday, November 21, at the George R. Brown Convention Center (1001 Avenida De Las Americas). Learn more.

November 20-21 — Global Corporate Venture 

Never has the energy industry been more vulnerable to disruption, but as open to change. The world's leading energy and transportation companies are using venture capital to invest in, and help deploy, new technologies and business models that will fundamentally change the way we generate, distribute and use energy.

Details: The event is from Wednesday, November 20, to Thursday, November 21, and takes place at various locations throughout the two-day conference. Learn more.

SpaceCom is the place for NASA, aeronautics, and anyone intersted in space. Photo courtesy of SpaceCom

NASA's SpaceCom lands in downtown Houston

Out of this world

The galaxies of science, astronomy, and pop culture have collided with the November 26 landing of NASA's InSight probe on Mars. As the world celebrates this critical mission, locals can explore the worlds of NASA, aerospace, and industry with SpaceCom — The Space Commerce Conference and Exposition, a two-day space extravaganza running November 27 to 28 at the George R. Brown Convention Center.

SpaceCom invites industry professionals, global leaders, and decision makers shaping the commercialization of space to discover where technology and innovation can take us, according to a release. Focusing on Earth and in near and deep space, SpaceCom provides attendees a chance to rub elbows with NASA departments, discuss the International Space Station, and exchange ideas on deep space exploration.

The convention will also integrate international space agencies and companies, providing a chance to form partnerships and collaborate on space initiatives with professionals from more than 30 countries. Industry pros can see how the world of space exploration can improve improve the tools, machines, devices, and services we use every day here on Earth in the fields of energy, advanced manufacturing, medicine, agribusiness, and maritime, per the statement.

It wouldn't be a convention without a chance to roam the interactive exhibit hall, plus there's a chance to participate in NASA presentations. Given the recent Mars news and the Johnson Space Center connection, this event promises to be a real blast for space fans.

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This story originally appeared on CultureMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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