Here's what this wealth management adviser wants you to know before you start your business. Photo via Getty Images

May is Small Business Appreciation month and as a Houstonian, small business owner and wealth management advisor, I understand firsthand the questions, considerations and challenges involved with navigating the nuanced world of small business ventures.

In 2005, I started RSF Wealth Management with my business partner. RSF Wealth Management is a Houston-based firm of Northwestern Mutual focused on comprehensive, collaborative and educational financial planning.

Understanding that every startup is different, I believe there are a few key strategies to keep in mind when starting a business.

1. Create a comprehensive business plan

Any lucrative, viable business has to start with a good plan that outlines what you will need to grow revenue and thrive long-term. Creating this strategic business outline will serve as a roadmap for your beginning years as well as a marketing tool when finding investors. The business plan should highlight what your outlook is for the next five years, how you will leverage your product to make profit, and how much money you will need to achieve and maintain financial success—no matter what scenario may come your way.

2. Establish a solid financial foundation

As most startup businesses take up to five years to turn over profit, it is important to receive funding or set aside extra cash, even if it’s a small amount. My advice to small business owners is to make sure you have at least six months to a years’ worth of liquidity before starting a business venture. Emergency savings funds and other cash reserves can help to cover the operational and overhead costs to startups. If you don’t have enough in your personal savings or cash reserves, there are loan options for small businesses, including the paycheck protection program loan, economic injury disaster loan, traditional SBA 7(A) loan and SBA express bridge loan.

3. Verify everything is documented

Documenting everything is crucial when building the foundation of your business for both legal and tax purposes. Not only will this help if something goes wrong with your business, but it will also keep formal structure between you and your business partner. All startups should complete a buy-sell agreement, which details how your partners’ share will be obtained by the remaining partners in case of their death or leave. I also recommend filing a morality clause contract, which requires all employees to comply to behavioral standards during the life of their contract.

4. Review your insurance and tax options

Small business owners should be regularly reviewing their tax and insurance options to ensure they are updated to reflect changing business needs. For instance, the SECURE Act 2.0 tax credit is a new incentive designed to make it easy and affordable for small businesses to offer employer-sponsored retirement plans. The new legislation allows increased tax credits to small businesses to encourage plan sponsorship and improve retirement readiness.

Additionally, business insurance for startups can help cover costs associated with property damage or liability claims. For example, disability overhead expense insurance provides your business with money to pay for everyday operational expenses in the event you’re unable to work due to an illness or injury. Generally, if you provide coverage for employees and cover the premium, you will be able to deduct those costs as a business expense.

Despite the difficulties of making the jump from employee to entrepreneur, 5 million new businesses were created in 2022 according to a study by the US Census Bureau. New businesses are being created every day and with the excitement of starting a new business also comes the complexities and challenges associated with a new business venture.

Financial advisors and industry experts can help you create a plan, understand what loan option is right for you and how much you will need to have in cash reserves to ensure you can securely and stably run your new business. No matter the size or operation of your business, financial advisors can help document your finances and connect you with the right attorney or accountant to set you up for long-term success.

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Keith Rollins is a wealth management advisor with Northwestern Mutual and a founding partner of RSF Wealth Management.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.