A new report finds that the Lone Star State isn't prime for innovation jobs — and more Houston innovation news. Photo via Getty Images

Houston's summer has been heating up in terms of innovation news, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, Houston investors were tapped for impressive roles, a local hospital system has invested in the city's diversity and inclusion, and more.

Houston Methodist awards more than $4.6 million for 2022 DEI Grant program

Ryane Jackson, vice-president, community benefits at Houston Methodist, oversees the grant program. Photo courtesy of Houston Methodist

Houston Methodist announced grants to 59 Houston-area nonprofit organizations totalling more than $4.6 million thanks to the Houston Methodist Diversity, Equity & Inclusion Grant Program. The program supports "community initiatives focused on addressing the social determinants of health that lead to health inequities within racial, ethnic and social minorities, including women, people experiencing homelessness, older adults, the LGBTQ+ community, immigrants and more," per a news release.

It's the second year for the DEI Grant Program, and the latest donations will support more than 100,000 people in the Houston area through 29 healthy neighborhood programs, 16 economic empowerment programs, and 17 educational empowerment programs.

“It’s incredibly encouraging to see so many local non-profit organizations working to close the health and social disparity gaps that exist among minority groups in the Houston area,” says Ryane Jackson, vice-president, community benefits at Houston Methodist, in the release. “The goal of the Houston Methodist DEI grant program is to enact meaningful change. For us, that change entails working together with local charity agencies in our collective pursuit to build a healthier Houston that reaffirms the value and worth of everyone. Entering our second year of funding, we’re pleased to support even more local organizations this year who are critical in shaping our community.”

The program has two types of grant funding — the Social Equity Grant for health equity programs targeting racial and ethnic minorities, and the DEI Grant, which provides resources for operating growing agencies serving broader minority communities.

Some examples of the grants are:

  • DEI Grant to the The Montrose Center, which empowers the LGBTQ+ community and their families to live healthier, more fulfilling lives. DEI grant funds will benefit LGBTQ+ seniors and African American seniors from Third Ward in need of affordable and affirmative housing and will enable the hiring of a case manager to support the initiative.
  • DEI Grant tp the Santa Maria Hostel, which offers a comprehensive continuum of care for women and their families including residential detoxification, substance use disorder treatment for women, and emergency and transitional housing. DEI Grant funding will support the Recovery Support Services Program that assists formerly incarcerated women with housing and economic stability through salary support for Peer Recovery Coaches. This agency is the only recovery agency that allows women to keep their children with them while going through the program.
  • Social Equity Grant to Boat People SOS - Houston, a nonprofit social and legal services provider whose purpose is to empower, organize, and equip immigrant communities in their pursuit of liberty and dignity. The Houston Methodist Social Equity grant funding will support their senior services program designed to address social support needs and provide resources to Vietnamese seniors.

2 Mercury investors named to prestigious programs

Samantha Lewis and Aziz Gilani of Mercury have each received exciting appointments. Photos via Mercury

Houston-based venture capital firm has two employees to celebrate. Samantha Lewis, principal at Mercury, was announced as a member of the Class 27 of the Kauffman Fellows Program, a group of global innovation investors, just after Aziz Gilani, managing director at the firm, was appointed to the National Advisory Council on Innovation and Entrepreneurship, a Federal advisory committee that advises the United States Secretary of Commerce.

For Lewis, the appointment enrolls her in the two-year program, which is described as "a United Nations of venture investing," in a news release. She joins a network of 765 fellows — including 59 in the current cohort — spanning six continents and representing over 670 VC firms around the globe.

At NACIE, Gilani was one of 32 leaders appointed by U.S. Secretary of Commerce Gina M. Raimondo last month. The group, according to a news release, will be tasked with "developing a National Entrepreneurship Strategy that strengthens America’s ability to compete and win as the world’s leading startup nation and as the world’s leading innovator in critical emerging technologies."

Texas ranks as middle of the pack when it comes to innovative states

Texas ranks in the lower half of the nation when it comes to innovation jobs. Chart via Smartest Dollar

The Lone Star State was named the 30th most innovative state, according to a new report from Smartest Dollar. The report evaluated data from 350 metros and all 50 states and sought to identify the locations with the most innovative workers. Researchers calculated a composite innovation index for each location and ranked states accordingly.

Here is a summary of the data for Texas, according to the report:

  • Composite innovation index: 59.30
  • Share of workers in the most innovative jobs: 2.6 percent
  • Total workers in the most innovative jobs: 322,910
  • Average annual wage for all workers: $54,230
  • Average annual wage for workers in the most innovative jobs: $77,098

Here are the statistics for the entire United States:

  • Composite innovation index: 59.53
  • Share of workers in the most innovative jobs: 3.1 percent
  • Total workers in the most innovative jobs: 4,428,790
  • Average annual wage for all workers: $58,260
  • Average annual wage for workers in the most innovative jobs: $86,562

Applications are open for pitch competition

A new pitch competition is looking for finalists. Photo via Getty Images

Applications are now open for the Black Girl Ventures x Omaze Houston pitch competition. The deadline to submit is July 1.

This fall, seven finalists will pitch their businesses to a panel of judges, and the first place winner will win $10,000. Second and third place winners will receive $6,000 and $2,000, respectively. Capital One will match funds, effectively doubling the prize money for the top three finalists.

Eligibility includes Black and Brown woman-identifying founders with revenue-generating (under $1 million) businesses. Founders can submit their applications online. Finalists will be notified on July 18.

Black Girl Ventures has been active in Houston since 2020. According to the organization, the region has six Change Agents, or fellows, who work to strengthen and expand the local entrepreneurial ecosystem.

Houston startup joins national 5G accelerator cohort

Houston startup joins a cohort of companies changing the future of 5G. Photo via Getty Images

A Houston company has been named to a new 5G-focused accelerator program. The gBETA 5G Technology Spring 2022 cohort includes Houston-based Ohana. Using advertising revenue, the company brings free access to information and connectivity to the world and is planning to roll out a 5G smartphone and data plan free to users across the globe later this year.

gBETA, which has an industry agnostic cohort ongoing in Houston, also has this 5G-focuset version that follows a similar structure. The five companies will go through the free, seven-week accelerator — that kicked off May 5 — and receive intensive and individualized coaching and access to gener8tor’s national network of mentors, customers, corporate partners, and investors.

The program will culminate with the gener8tor Showcase Day in the fall, which will highlight each of the five companies.

“We’re so fortunate to have such a diverse set of founders from across the country, with expertise across the internet technology and communications continuum,” says Doug Applegate, gBETA director for the 5G Technology program. “They highlight the capabilities and possibilities of what 5G Technology can bring to the world, and we’re excited to see how the companies grow.”

The other companies include Chicago-based Socian Technologies, Fishers, Indiana-based Qumulex Boston-based Mentore, and Dallas-based Taubyte.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.