A Houston space medicine research organization has partnered with a video game maker that has created surgery simulation technology. Photo via levelex.com

A Houston-based organization affiliated with NASA has teamed up with a video game company to advance virtual simulation in space medicine.

The Translational Research Institute for Space Health, known as TRISH, in partnership with NASA in a consortium led by Baylor College of Medicine, California Institute of Technology in Pasadena, and Massachusetts Institute of Technology in Cambridge has advanced a new approach for space medicine using video game technology by collaborating with video game company, Level Ex.

"We discovered Level Ex through a process of landscaping the many virtual simulation companies that were out there," says Andrew Peterman Director of Information System at TRISH. "We especially noted those that were on the cutting edge of the technology."

Based in Houston, TRISH aims to collaborate with the best and the brightest to revolutionize space health, providing grants to companies with innovative concepts. With Level Ex, they found a new approach to decode earthly medical technologies in space.

Level Ex, a Chicago-based company created in 2015 was founded to provide training games for doctors to use to practice surgeries and procedures. The games are interactive, with the virtual patient reacting to the actions of the player. The training simulations consist of in-depth and physics-driven medical simulations that are verified by doctors in their advisory board.

"We're hoping to completely change the ways that doctors stay up to speed," says Level Ex founder-and-CEO Sam Glassnberg.

With their ongoing collaboration with TRISH, they have a challenge that's out of this world. In space, astronauts have limited space for medical tools and run on a limited crew. This makes providing basic medical training to all astronauts especially important.

Especially since the body begins to react to the new environmental conditions of space missions. The effects can be small or lead to new changes or challenges for astronauts who take on long-range missions. Astronauts may see their bodies slowly start to lose bone and muscle mass. Their fluid begins to shift toward their head, leading to increased risks of hypertension and thrombosis.

All of these are challenges NASA is working to address with the help of gaming technology from Level Ex that innovates the technology with higher-level capability and training. Combining video game technology and medical simulation applications to incorporate and explore the interplay of environmental conditions found in space.

"What we really liked about Level Ex is that they have an amazing team both on the clinical and technical side, says Peterman. "They are a group of former big-name game developers who along with clinical experts have married technology and medicine with their platform producing full in engine physics-driven real simulations rather than video playback."

The astronauts will train using simulations that allow them to practice a procedure in zero gravity conditions and even simulate the gravity conditions of Mars. The game will also allow astronauts to get their own on-screen avatar with their medical information thus allowing fellow astronauts to gain more practice and experience with fewer variables in space.

The advanced medical simulation platform has potential for commercial uses on earth, improving the range of the technology to simulate new, rare, and complex scenarios across a range of medical specialties, allowing doctors to practice a range of difficult scenarios without putting patient lives at risk.

Peterman says that the partnership is expected to continue into the future for immediate applications along with other innovations in astronaut healthcare, including autonomous frameworks to provide medical knowledge in outer space.

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Houston maritime startup raises $43M to electrify vessels, opens new HQ

Maritime Mission

A Houston-based maritime technology company that is working to reduce emissions in the cargo and shipping industry has raised VC funding and opened a new Houston headquarters.

Fleetzero announced that it closed a $43 million Series A financing round this month led by Obvious Ventures with participation from Maersk Growth, Breakthrough Energy Ventures, 8090 Industries, Y Combinator, Shorewind, Benson Capital and others. The funding will go toward expanding manufacturing of its Leviathan hybrid and electric marine propulsion system, according to a news release.

The technology is optimized for high-energy and zero-emission operation of large vessels. It uses EV technology but is built for maritime environments and can be used on new or existing ships with hybrid or all-electric functions, according to Fleetzero's website. The propulsion system was retrofitted and tested on Fleetzero’s test ship, the Pacific Joule, and has been deployed globally on commercial vessels.

Fleetzero is also developing unmanned cargo vessel technology.

"Fleetzero is making robotic ships a reality today. The team is moving us from dirty, dangerous, and expensive to clean, safe, and cost-effective. It's like watching the future today," Andrew Beebe, managing director at Obvious Ventures, said in the news release. "We backed the team because they are mariners and engineers, know the industry deeply, and are scaling with real ships and customers, not just renderings."

Fleetzero also announced that it has opened a new manufacturing and research and development facility, which will serve as the company's new headquarters. The facility features a marine robotics and autonomy lab, a marine propulsion R&D center and a production line with a capacity of 300 megawatt-hours per year. The company reports that it plans to increase production to three gigawatt-hours per year over the next five years.

"Houston has the people who know how to build and operate big hardware–ships, rigs, refineries and power systems," Mike Carter, co-founder and COO of Fleetzero, added in the release. "We're pairing that industrial DNA with modern batteries, autonomy, and software to bring back shipbuilding to the U.S."

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This article originally appeared on EnergyCapitalHTX.com.

Innovative Houston-area hardtech startup closes $5M seed round

fresh funding

Conroe-based hardtech startup FluxWorks has closed a $5 million seed round.

The funding was led by Austin-based Scout Ventures, which invests in early-stage startups working to solve national security challenges.

Michigan Capital Network also contributed to the round from its MCN Venture Fund V. The fund is one of 18 selected by the Department of Defense and Small Business Administration to participate in the Small Business Investment Company Critical Technologies Initiative, which will invest $4 billion into over 1,700 portfolio companies.

FluxWorks reports that it will use the funding to drive the commercialization of its flagship Celestial Gear technology.

"At Scout, we invest in 'frontier tech' that is essential to national interest. FluxWorks is doing exactly that by solving critical hardware bottlenecks with its flagship Celestial Gear technology ... This is about more than just gears; it’s about strengthening our industrial infrastructure," Scout Ventures shared in a LinkedIn post.

Fluxworks specializes in making contactless magnetic gears for use in extreme conditions, which can enhance in-space manufacturing. Its contactless design leads to less wear, debris and maintenance. Its technology is particularly suited for space applications because it does not require lubricants, which can be difficult to control at harsh temperatures and in microgravity.

The company received a grant from the Texas Space Commission last year and was one of two startups to receive the Technology in Space Prize, funded by Boeing and the Center for the Advancement of Science in Space (CASIS), in 2024. It also landed $1.2 million through the National Science Foundation's SBIR Phase II grant this fall.

Fluxworks was founded in College Station by CEO Bryton Praslicka in 2021. Praslicka moved the company to Conroe 2024.