Meet the 4 corporations best supporting Houston's innovation ecosystem

Houston innovation awards

The Corporate of the Year category for the Houston Innovation Awards has four finalists — each playing a role in Houston's innovation ecosystem across energy, tech, and health care innovation. Photos courtesy

What corporations are most supporting Houston's startup ecosystem? The Houston Innovation Awards sought to find that out with a new category for the 2023 event.

The Corporate of the Year category has four finalists — each playing a role in Houston's innovation ecosystem across energy, tech, and health care innovation. Learn about each of these finalists in the interviews below.

Click here to secure your tickets to the November 8 event where we announce the winner of this exciting new category.

Aramco Ventures

Jim Sledzik, North American managing director of Saudi Aramco Energy Ventures, leads the organization locally. Photo via Aramco

Describe your company's work within the Houston innovation ecosystem.

Aramco Ventures has supported the development of Houston's innovation ecosystem as a founding member of the Ion to advance energy transition and Houston's tech economy. Jim Sledzik, managing director, Aramco Ventures North America, serves on the Ion Advisory Council. In addition we support Greentown Labs with its offices in Boston and Houston with Sledzik also named to its Advisory Board. Aramco Venture professionals are frequently tapped as speakers and participants for numerous industry speaking events and "Pitch Competitions" for start-up companies. For example, the 20th Annual Energy Tech Venture Forum held in Houston and organized by the Rice Alliance for Technology and Entrepreneurship; Climate Week NYC; and the first ever Women's Capital Summit in New York City.

Why has your company decided to support the Houston innovation ecosystem?

Houston is considered the energy capital of the world and Aramco's support and involvement will help amplify the city's reputation and presence as a global energy hub.

Describe your company's impact on the Houston innovation ecosystem.

Aramco's impact has been felt throughout the city by our involvement in major innovation events, activities, and investments.

Chevron Technology Ventures

Jim Gable, vice president of innovation at Chevron and president of Chevron Technology Ventures, leads the organization locally. Photo courtesy

Why has your company decided to support the Houston innovation ecosystem?

Investing in the communities where we operate is a core Chevron value, and Chevron is committed to building the innovation ecosystem in Houston. It’s good for our company and it’s good for the city.

The Houston region, with its deep pool of engineering and industry talent, world-class university expertise, growing startup community and vast energy infrastructure, is well-positioned to lead in the creation of lower carbon energy and improve the region’s global competitiveness. By leveraging its strengths, Houston can create its own model for how it’s going to disrupt the energy space.

Describe your company's impact on the Houston innovation ecosystem.

At Chevron Technology Ventures, we leverage our trial and deployment resources, venture investments and strategic partnerships – both internal and external – to support the technological breakthroughs that will enable the evolution to a lower-carbon energy system. CTV is an active sponsor of university programs and accelerators that build up the Houston energy ecosystem. It has led Chevron’s founding partnership with Greentown Labs Houston and was The Ion’s first tenant and program partner. CTV also backs The Cannon and Rice Alliance Clean Energy Accelerator, among others. As a partner and supporter of the innovation ecosystem, Chevron is committed to helping the ecosystem thrive.

Houston Methodist

Michelle Stansbury, vice president of innovation and IT applications at Houston Methodist, leads the company's innovation efforts. Photo courtesy of Houston Methodist

Describe your company's work within the Houston innovation ecosystem.

Our new collaborative space, the Tech Hub at Ion, is one way we are expanding our culture of innovation within Houston and its growing innovation ecosystem. Beyond showcasing ongoing technology, the Tech Hub at Ion also serves as a nucleus for community engagement and networking and hosting educational initiatives, with additional programming opportunities like reverse pitch sessions in the works.

Why has your company decided to support the Houston innovation ecosystem?

Healthcare is evolving at a rapid pace thanks to digital technology, so it’s important to search for solutions that are beyond the traditional walls of the hospital and even beyond our own industry. Serving our patients both in and outside the walls, especially in the community, has been a priority for Houston Methodist since our inception. We’ve had success in the healthcare innovation space, so we think it’s important to pay it forward and support the Houston innovation community.

Describe your company's impact on the Houston innovation ecosystem.

Our new collaborative space, the Tech Hub at Ion, is one way we are expanding our culture of innovation within Houston and its growing innovation ecosystem. Beyond showcasing ongoing technology, the Tech Hub at Ion also serves as a nucleus for community engagement and networking and hosting educational initiatives, with additional programming opportunities like reverse pitch sessions in the works. Houston Methodist’s Center for Innovation often collaborates with technology companies with solutions that provide a better patient experience and/or support clinicians and often these are technology companies early in their start-up journey. One Houston start-up Houston Methodist at the beginning of the pandemic and continues to use is MIC Sickbay, the technology that powers the virtual ICU and uses algorithms and AI to monitor patients.

Microsoft

Rob Schapiro, Energy Acceleration Program director and Houston site leader for Microsoft, leads the company's local innovation support efforts. Photo courtesy of Microsoft

Describe your company's work within the Houston innovation ecosystem.

Microsoft is committed to driving tech and innovation in the Houston community with a specific focus on underrepresented communities. Microsoft is financially supporting the ion, Greentown Labs Accel, DivInc, Tejano Tech Summit, and the Rice Alliance Clean Energy Accelerator as well as programs designed to bring the next generations of Houston founders to the forefront (G-Unity Business Lab, SuperGirls Shine Foundation, Tech Fest Live, PVAMU). Aside from the financial support, Microsoft brings a dedicated team of volunteers and mentors to each of these engagements, and they are helping shape the future of innovation in the city of Houston.

Why has your company decided to support the Houston innovation ecosystem?

We believe that it is our duty to be an active and engaged corporate partner to any and all communities in which we operate. We decided to invest in Houston because of the rich, diverse talent pool and the growing energy transition industry.

Describe your company's impact on the Houston innovation ecosystem.

  • Partnered with DivInc to create an Energy Tech Accelerator program that had its first cohort of seven companies this year.
  • Driving thought leadership and bringing attention to valuable initiatives through serving on the advisory boards of the Ion (Vice Chair position), Greentown Labs Houston, Rice Alliance Clean Energy Accelerator.
  • Supporting the next generation of innovators: 120 high school students received hands on training in innovation and prototyping as part of the G-Unity Business Lab. This program doubled in size due to its success. Microsoft sponsored prototyping and design thinking training. We also seated one of the Hustle Tank judges.
  • Graduated 14 students from the Level Up fellowship program in partnership with Prairie View A&M University and Accenture; most students received and accepted employment offers from Accenture.
  • Sponsored 20 high school girls who participated in the SuperGirls Shine Foundation's 40/40 mentorship program.
  • Ten women founders received mentoring and training as part of the DivInc Women in Tech Cohort
  • Held a four-week high school internship program for BIPOC students

This week's roundup of Houston innovators includes Isabella Schmitt of Proxima Clinical Research, Rob Schapiro of Microsoft, and Lara Cottingham of Greentown Labs. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from medical device innovation to energy tech— recently making headlines in Houston innovation.

Isabella Schmitt, director of regulatory affairs at Proxima Clinical Research and principal at M1 MedTech

A Houston life science expert shares what she thinks Houston needs to work on to continue growing as an health care innovation ecosystem. Photo courtesy

Houston is home to the world's largest medical center, but it still tends to fall behind other metros when it comes to life science innovation hub rankings. Isabella Schmitt, director of regulatory affairs at Proxima Clinical Research and principal at M1 MedTech, writes in a guest column for InnovationMap about why this is — and what can be done to change that.

"Houston's life sciences sector holds immense growth potential, but addressing funding, talent recruitment, regulatory navigation, and collaboration challenges is needed for continued success," she writes. "By tackling these issues and leveraging its unique strengths, Houston can establish itself as a significant player in the global life sciences arenas. If we wait too long, we won’t be able to truly establish the Third Coast because another player will come into the mix, and we’ll lose companies like BioMatrix to their golden shores." Read more.

Rob Schapiro, Energy Acceleration Program director and Houston site leader for Microsoft

Rob Schapiro of Microsoft joins the Houston Innovators Podcast to discuss DEI initiatives, translating between the tech in the energy sectors, AI, and more. Photo courtesy of Microsoft

At a glance, Rob Schapiro admits his resume might not make the most sense. A trained geologist with decades of experience in the energy sector, Schapiro made the move to Microsoft three years ago.

"I saw this disconnect between technology companies and energy companies — they didn't really speak the same language," he says on this week's episode of the Houston Innovators Podcast. "I thought I could help potentially solve this problem and work between the two as a sort of translator."

Now, as Microsoft’s Energy Acceleration Program director and site leader for the company’s Houston office, which is located in the Ion, Schapiro is deeply embedded in Houston's innovation ecosystem and is dedicated to helping advance Houston's role energy transition in a sustainable and equitable way. Read more.

Lara Cottingham, vice president of strategy, policy, and climate impact at Greentown Labs

Greentown Houston is asking its current and potential members what they want in a wet lab. Photo via GreentownLabs.com

Greentown Labs is in the early stages of building out a wet lab for its members. But first, Lara Cottingham, vice president of strategy, policy, and climate impact at Greentown Labs, says they want to know what their members actually want.

"We want to announce to the community that this is something we're going to build — but we still need a lot of feedback and input from startups so we can learn what exactly they need or want to see from the wet lab," Cottingham tells InnovationMap. "No two wet labs are the same."

Right now, there aren't any details available about timeline or specifics of the new facility. Greentown is prioritizing getting feedback from its members and having conversations with potential sponsors and corporate partners. Read more.

Rob Schapiro of Microsoft joins the Houston Innovators Podcast to discuss DEI initiatives, translating between the tech in the energy sectors, AI, and more. Photo courtesy of Microsoft

Meet the innovator who's leveraging big tech to advance Houston's ecosystem equitably

HOUSTON INNOVATORS PODCAST EPISODE 188

At a glance, Rob Schapiro's resume might not make the most sense. A trained geologist with decades of experience in the energy sector, Schapiro made the move to Microsoft three years ago.

"I saw this disconnect between technology companies and energy companies — they didn't really speak the same language," he says on this week's episode of the Houston Innovators Podcast. "I thought I could help potentially solve this problem and work between the two as a sort of translator."

Now, as Microsoft’s Energy Acceleration Program director and site leader for the company’s Houston office, which is located in the Ion, Schapiro is deeply embedded in Houston's innovation ecosystem and is dedicated to helping advance Houston's role energy transition in a sustainable and equitable way.

Inspired by the murder of George Floyd, Schapiro says he sought out opportunities in his personal life to expand his contribution to the community as an ally, and he became a big brother in Big Brothers Big Sisters. Microsoft, too, is active in supporting the community through partnering with local organizations, including SUPERGirls SHINE Foundation, the G-Unity Foundation Inc., and more.

"This has been one of the most rewarding aspects of my job, that I've had the ability to leverage the might of Microsoft and my own privilege to have an impact on real people," Schapiro says. "Microsoft's mission is to empower every person and every organization on the planet to achieve more, and when you think about how you do that, it's really daunting. We realized that in order to do that, it's going to require a workforce that looks really different than it does today."

Microsoft knows too well the changing workforce, both from a diversity perspective and when it comes to artificial intelligence and other new technology. In its recent Work Trend Index report, the company found that, rather than being afraid of AI replacing jobs, the majority of the workforce is interested in applying AI to mundane tasks.

Schapiro shares more about his view of how AI will affect the workforce, plus what all the energy industry needs to focus on amid the energy transition, on the podcast. He also weighs in on how Houston's innovation ecosystem has evolved and where he hopes it's going. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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