Exclusive: New Houston accelerator reveals its inaugural cohort and announces strategic partner

Smart Cities

The Ion Smart Cities Accelerator — named for its to-be home, The Ion — announced the 10 companies selected for the first cohort. Courtesy of Rice University

The Ion Smart Cities Accelerator launched earlier this year with a goal of engaging startups from around the world to solve some of Houston's most prevalent challenges. Backed by Intel and Microsoft and partnered with the city of Houston and Station Houston, the program has developed a curriculum and selected its first cohort.

Ten startups from around the world — half of which from right here in Houston — were selected to be a part of the program. And narrowing down to 10 was tough for the program's judges, says Christine Galib, director of the Ion Smart Cities Accelerator.

"Selecting the participants for our first cohort was difficult, due to this amazing pool of talent — that's always the problem you want to have," she tells InnovationMap.

The program will be a 10-month process, beginning Wednesday, September 4. The accelerator's Demo Day is scheduled for December 4, and then the participants will complete a pilot program with the city from January to June, Galib says.

Based on the issues the cohort aims to solve — resilience and mobility — the program and the city of Houston decided on Near Northside as a focus for the companies.

"We focused on aligning to the needs of the city of Houston and our spotlight community, Near Northside," Galib says. "We really considered the focus areas that we have identified that were needs or challenges in the area, like aging infrastructure or health and safety."

The entrepreneurs will attend local meetings, connect with the community, and zero in on the neighborhood for solutions. This provides a more accessible avenue of integration for each of the companies' technologies and allows for the entrepreneurs to receive feedback in real time from the community.

"One of my biggest things with the accelerator is technology will be for the people, and not the other way around. We're really hoping that we can build relationships with community members in Near Northside such that they'll be able to have access to our startups and their technology in a very integrated way."

Along with this new neighborhood focus, the program also announced a partnership with the University of Houston.

"We're collaborating with the UH Technology Bridge such that professors, researchers, and startups associated with UH can have a pipeline from the world of academia and research to industry and urban planning," says Galib.

Here are 10 selected startups for the inaugural cohort.

Aatonomy

Houston-based Aatonomy has developed a device that allows for Houston drivers to instal self-driving technology in their own vehicles.

"They're basically Tesla's autopilot — but for cars we already own," Galib says.

The technology makes for safer, smarter driving around town.

AeoShape

Another homegrown company, AeoShape is in the business of compiling data and making it easier to use — from facial analysis to location-based services, the company is taking data and organizing it to more easily use it for finding solutions or strategies.

"Imagine having all the big data served up anywhere at any time in a comprehensive, visual way," Galib says.

BlocPower

Based in New York, BlocPower is connecting the dots in the consumer energy world. The startup links up with government entities, utilities contractors and more to engage IoT, machine learning, and structured finance technology to better provide clean energy in American cities.

"This is pairing the different segments in the building and infrastructure world in a way that makes sense so that they can build in an integrated way," Galib says.

GoKid

Another New York company, GoKid has a solution for carpooling. In a world so conveniently filled with ridesharing technology, busy parents still struggle to find safe rides home for their kids. The free app allows for parents to connect with one another in a way never before been optimized for school pick-up and drop-off.

"We see GoKid really working with our schools here to make ridesharing safer," Galib says. "We really like them because they were a solution for the ridesharing challenge — a lot of parents who might need carpooling services don't necessarily trust an Uber driving that they don't know."

Kriterion

Artificial intelligence company Kriterion is based in South Africa, but will soon call Houston home. The company takes AI a step further in its industry and infrastructure approach.

"We see their platform shaping three areas of Houston: waste management, power system management, and pothole detection and maintenance management," says Galib.

Sensytec

 Sensytec comes out of the University of Houston and uses is technology to monitor, analyze, and quantify cement and concrete conditions.

"We thought this was pretty cool to have in our cohort because Houston is quite the concrete jungle," says Galib.

The company was also recently named a top startup in MassChallenge Texas' inaugural Houston cohort.

SlideX

Houston-based SlideX has solutions for everyone's daily struggle: Parking. The company's technology has applications for finding parking in the city — including a 3D map to help direct you — and even for paying for parking.

"They call themselves 'the next generation of intelligent parking,'" Galib says.

Umanity

San Francisco-based Umanity has created a philanthropic supply chain tool. The technology can match and map local nonprofit needs to volunteers and donations, plus provide real-time analytics.

"This is kind of the epitome of doing good and adds a very strong social enterprise and community base component to our startups," says Galib.

Wyzerr

Kentucky startup Wyzerr specializes in easy-to-use surveys.

"We think Wyzerr can provide a good feedback platform where the city of Houston, businesses, and nonprofits can easily engage with people all over the city to find out how satisfied they are with the businesses and services the city provides," Galib says.

The company's technology can be crucial for tracking KPIs and progress.

"When you're creating a Smart City, there are obviously objectives you set for what you consider to be a Smart City, but also there are ways to measure how well you're meeting those objectives," she adds.

Reality IMT

Houston-based Reality IMT is engaging the latest technology tools to digitize infrastructure.

"This really speaks to understanding our infrastructure and ways to make it safer and more efficient, and also understanding the data associated with that," says Galib.

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Microsoft partners with Rice University's OpenStax on AI teaching tool

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Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

Houston ranks among the 15 best cities in America for 2025

Ranking It

A new national report ranking the best cities in America has declared Houston is the 13th best U.S. city in 2025.

The annual "America's Best Cities" report from Resonance Consultancy, a Canada-based real estate and tourism marketing firm, ranks the relative qualities of livability, cultural "lovability," and economic prosperity in America's principal cities with metropolitan populations of 500,000 or more.

These top 100 cities "brilliantly weave local culture with economic prospects, aligning with global and domestic travel trends to create premier experiences for both residents and travelers."

Houston's new placement is three spots lower than its triumphant No. 10 rank in 2024. Though it no longer holds a prized top-10 spot, the report hails Houston as a "coveted hometown for the best and brightest on earth."

Among Houston's other shining attributes are its booming population growth – which has now grown to a staggering 7.51 million people – plus its competitive real estate market and a vibrant hospitality and culinary scene. Additionally, Houston earned a well-deserved No. 4 rank in the report's "restaurants" subcategory.

"A 221-room Home2 Suites/Tru by Hilton debuted near Toyota Center in March, while Marriott’s newly renovated Residence Inn NASA/Clear Lake keeps surging visitors happy," the report said. "West Houston’s Greenside will convert 35,000 square feet of warehouses into a park-laced retail hub by 2026, while America’s inaugural Ismaili Center, rising along Allen Parkway, remains on schedule for later this year, adding yet another cultural jewel to H-Town’s festival-fueled mosaic."

The report additionally puts a large focus on Houston's innovative energy sector and its numerous large companies that boost the local economy and create thousands of jobs. Several of these Houston-based companies are some of the best places to work, according to U.S. News and World Report.

One such company that was specifically praised in the report was the HyVelocity Hub, which aims to "ensure economic resilience and long-lasting, domestic energy production" along the Gulf Coast.

"The HyVelocity Hydrogen Hub just locked in up to $1.2 billion from the U.S. DOE, targeting 45,000 jobs and slicing 7.7 million tons of CO₂ a year," the report said.

Elsewhere in Texas

Dallas (No. 14) and Austin (No. 15) ranked right behind Houston in the top 20, while San Antonio sank into the No. 41 spot after previously ranking 32nd last year. El Paso also fell from No. 83 in 2024 to No. 100 this year.

Jason McGrath, the executive vice president and head of U.S. Corporate Reputation at Ipsos, said in the report that American cities are proving their resiliency as they are faced with "climate issues, increasing infrastructural demands, and shifting geopolitical landscapes affecting international relations and travel."

"Despite these hurdles, cities are creatively reinventing themselves to shine as examples of cultural vibrancy and innovation, keeping their competitive edge both locally and globally," McGrath said. "Our report shows that the allure of American cities remains strong, thanks to their rich diversity and vast attractions — from natural wonders to buzzing cultural hubs."

The top 10 best cities in America in 2025 are:

  • No. 1 – New York City, New York
  • No. 2 – Los Angeles, California
  • No. 3 – Chicago, Illinois
  • No. 4 – San Francisco, California
  • No. 5 – Seattle, Washington
  • No. 6 – Miami, Florida
  • No. 7 – Boston, Massachusetts
  • No. 8 – Washington, D.C.
  • No. 9 – Las Vegas, Nevada
  • No. 10 – San Diego, California
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This article originally appeared on CultureMap.com.

Houston biosciences company opens new sequencing center for drug development

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Houston-based Avance Biosciences has launched the Next-Generation Sequencing Center of Excellence, designed to enhance the company’s sequencing capabilities for drug development. Specifically, the facility at the company’s main campus in Northwest Houston will pursue breakthroughs in biologics, cell therapy and gene therapy.

In the drug industry, sequencing refers to studying nucleotides in DNA and RNA molecules. Nucleotides are the building blocks of DNA and RNA.

“This is a major milestone for Avance Biosciences as we continue to support the evolving needs of biologics and cell and gene therapy developers,” Xuening “James” Huang, co-founder, CEO and chief technology officer of Avance, said in a news release. “By consolidating state-of-the-art sequencing platforms and scientific talent, we’ve created a highly capable organization ready to solve complex genomic challenges with precision and compliance.”

In 2013, Avance rolled out next-generation sequencing (NGS) that complies with federal guidelines. Since then, Avance “has remained at the forefront of regulated sequencing services,” the company said. “The launch of the (new center) strengthens the company’s ability to deliver accurate, reproducible, and regulatory-aligned sequencing data across a wide array of therapeutic modalities.”

Cal Froberg, senior vice president of sales and marketing at Avance, said pharmaceutical and biotech clients trust the company’s technical capabilities and regulatory compliance.

“With the ever-changing global landscape and increasing scrutiny around international sample shipments, conducting advanced, cost-effective NGS testing domestically is now more feasible than ever,” Froberg said. “Our clients have confidence that their samples will remain in the U.S.”

Avance, founded in 2010, plans to hold an open house at the new facility in September to showcase its capabilities, technology, talent, and services. The company’s services include sequencing, molecular biology, cell-based testing, and bioanalytical testing.
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