These three startups are innovating flood damage mitigation tools so that Houstonians can have peace of mind this hurricane season. Getty Images

In light of Houston's frequent floods, a local organization has formed to encourage innovation in resiliency — especially as the city moves throughout the 2020 hurricane season.

The Gulf Coast & Southwest Resilience Innovation Hub was founded last month by the Insurance Information Institute and ResilientH20 Partners in The Cannon's downtown location. The organization is looking into the best innovations within resiliency — especially as it pertains to Houston, where nine of the 10 most expensive hurricanes in the United States have occurred in the past 16 years.

"There has been a widespread interest in, and demand for, best-in-class actionable, alternative disaster mitigation solutions since 2017's Hurricane Harvey and subsequent storms caused extensive insured losses to autos, homes, businesses, and governmental properties," says Richard Seline, managing partner of ResilientH2O Partners, in a news release.

The organization held a virtual panel and pitch session that featured three flood-focused startups. Here are the three companies and their innovative solutions to flood mitigation.

True Flood Risk

True Flood Risk uses machine learning and artificial intelligence to assess a home's flood risk. Image via truefloodrisk.com

Shelly Klose founded her company, True Flood Risk, after she observed Hurricane Sandy devastating New Jersey. But, she wondered, why some homes were hit harder than others. So, she created an artificial intelligence-driven property risk management platform that would easily indicate how susceptible to flood damage each home is. The company even has a way to measure the property's first-floor height based street view images.

"With this key data point for structural height coupled with ground elevation and flood zone data, you have a good indication if that property is at risk," Klose says.

The New York-based company allows users to run their address and learn about their flood damage risk for free — and that's something Klose says thats a tool she's seen used more frequently amid the pandemic.

"What we're finding is people have been so emotionally and financially hit so hard during this pandemic," Klose says. "The last thing you want to do is lose your house."

FloodFrame

Self-deploying flood protection for buildings

FloodFrame is a self-deploying flood protection for buildings. Photo via floodframe.com

Part of the challenge of mitigating flood damage is that it can happen in an instant with little to no warning. FloodFrame provides a solution to that in its self-inflating technology that can detect and prevent flood damage.

FloodFrame works by using buoyancy. A lightweight cloth is wrapped around a tube is installed underground outside the perimeter of your home or business. One end of that cloth is attached to a box that is also installed underground. As flooding begins, an automatic system will release the lids to deploy the inflation of the tube that will protect the structure. When the flood comes in, the system will float on top of the flood — kind of like a pool noodle — and protect the structure from the water. It's easier to install than raising a house, for instance, and can be reused as a long-term solution.

Tasha Nielsen launched the U.S. iteration of FloodFrame — which originated in Denmark — by becoming the company's first franchisee. Now, that process how the company plans to grow and expand and Nielsen is working with home builders and contractors to provide the invention in new homes and buildings. Nielsen also hopes to work with insurance companies, since the device helps prevent costly payouts.

Climaguard

A waterproof container for your car.

Houston-based ClimaGuard is looking to help drivers protect their vehicles from floods. Photo via ClimaGuard/Facebook

Hundreds of thousands of cars were damaged during Hurricane Harvey, and those car owners faced financial burdens from having to find temporary transportation to repairing or even buying a new vehicle. Rahel Abraham, who lost her car during the storm, founded Houston-based ClimaGuard to help enable people to help protect their cars or possessions from the elements.

"We're providing a resilient, practical, and real-time solution," says Abraham.

The tool is easy to use and affordable, considering the costs of potential damages, with a starting price of $399. The average insurance payout for vehicles was $12,000, Abraham says, so it's actually a great risk mitigation tool for auto insurers.

Airports, spaceports, and carports — these three Houston innovators represent the city's future. Courtesy photos

3 Houston innovators to know this week

Who's who

This week's Houston innovators to keep an eye on are working on technologies that are true testaments to the day and age we live in. From commercial space travel to a product that protects vehicles from floodwaters that are more and more frequent, these entrepreneurs are providing solutions to problems no one even dreamed of having a few decades ago.

Mark Bergsrud, co-founder and CEO of Grab

Courtesy of Grab

For over 20 years, Mark Bergsrud worked at the intersection of travel and technology — first at Continental Airlines, then at United Airlines following the merger, and now for himself as the co-founder of Grab, a Houston startup that's making grabbing a bite at the airport way easier.

Grab's technology digitizes and optimizes the airport dining experience — from ordering pickup remotely ahead of time to kiosks or table tablet ordering. The company, which has operations in 37 airports, just closed a multimillion-dollar Series A fundraising round to help continue its growth.

"We've called ourselves a startup for a long time, and now we think of ourselves as more of a scale-up company," Bergsrud says. "Now it's about having the money to scale faster."

Read more about the company by clicking here.

Rahel Abraham, founder of ClimaGuard

Courtesy of ClimaGuard

For inventors, you can usually pinpoint a particular "eureka" moment. For Rahel Abraham, it was seeing her 2008 Infiniti G35 completely totaled by the rain waters of Hurricane Harvey. She knew there had to be some way to protect cars and valuables from flooding, so she invented ClimaGuard's Temporary Protective Enclosure.

Abraham, who was selected for the 12-week DivInc accelerator program in Austin for her company, wants to make the product available to everyone.

"My goal is not to make it to where it's an exclusive product — available only to those who can afford it — but I want to be able to help those who it would make even more of an economic impact for," Abraham says.

Read more about the company by clicking here.

Arturo Machuca, general manager of Ellington Airport and the Houston Spaceport

Arturo Machuca

Courtesy of the Houston Airport System

Arturo Machuca is playing a waiting game. Various companies are developing commercial spaceflight and — whether that technology delivers in two years or 10 years, Machuca wants Houston to be ready. Ellington Airport and the Houston Spaceport are being developed throughout a multiphase, multimillion-dollar process, while also serving as an active airport.

"We use what we already have at Ellington Airport," Machuca tells InnovationMap. "We're serving aviation today until commercial spaceflight gets here."

Read the full interview by clicking here.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”