Rice Alliance pitch event identifies 8 most-promising energy tech startups

ones to watch

The Rice Alliance for Technology and Entrepreneurship identified eight startups that are best suited for disrupting energy tech and innovation. Photo courtesy of Rice Alliance

In honor of CERAWeek, the Rice Alliance for Technology and Entrepreneurship hosted its annual Energy Venture Day.

After over 50 startup pitches and more than 300 meetings, venture investors identified eight startups that are the most-promising companies on a path to innovate and disrupt the energy ecosystem.

The 2023 Energy Venture Day's Most-Promising Startup winners were:

AeroShield Materials

Graphic via aeroshield.tech

Hyde Park, Massachusetts-based AeroShield Materials is creating thermally insulating transparent inserts. The inserts are only four millimeters of AeroShield's material and, when placed inside a double-pane window, provides 65 percent more energy efficiency.

Columbia Power Technologies (C-Power)

Image via cpower.co

C-Power, based in Charlottesville, Virgina, has a technology that harnesses the power of the ocean.

"C-Power delivers this renewable energy resource to the world, both through low-power solutions that bring energy and the cloud to the sea and large-scale solutions that help decarbonize terrestrial grids," the company's website reads.

EarthEn

Graphic via earthen.energy

Chandler, Arizona-based EarthEn is focused on long duration energy storage solutions that use CO2 in a closed loop to store 4 to 100 hours of energy at a low cost. The SaaS tools — with artificial intelligence and machine learning — optimize peak demand pricing and use predictive analysis to enable grid resiliency.

Group1

Photo via Twitter

Group 1, based in Austin, is focused on the commercialization of potassium-ion batteries. The core technology originates from the labs of University of Texas at Austin professor JB Goodenough, co-inventor of the lithium-ion battery.

Ionada Carbon Solutions

Photo via ionada.com

Houston-based Ionada, a member of Halliburton Labs, has created a technology that can remove up to 99 percent of the carbon dioxide emissions for the energy, marine, and e-fuels, according to the company.

"Our engineers have more than a century of combined expertise in reducing emissions for the power generation, chemical, road, rail, air and marine industries. We are here to help you find the best sustainable solution to reduce your emissions," reads the website.

H Quest Vanguard

Photo courtesy of Halliburton

Another Halliburton Labs member H Quest Vanguard, headquartered in Pittsburgh, has developed an electrically powered chemical conversion platform that leverages Microwave Plasma Pyrolysis to liberate zero-CO2 hydrogen from natural gas using only a quarter of energy required by electrolysis, while coproducing a high-value carbon or petrochemical coproduct.

Pressure Corp

Photo by Anton Petrus/Getty

Houston-based Pressure Corp is developing waste pressure power systems to help midstream gas companies solve how they reduce emissions by providing the technology, capital and expertise required to achieve their environmental, social and governance goals.

STARS Technology

Photo via starsh2.com

Based in Richland, Washington, STARS Technology Corp. is commercializing advanced micro-channel chemical process technology that originally was designed for NASA and the Department of Energy. The company's reactors and heat exchangers are compact, energy-efficient, and more.

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The Rice Alliance has named its second annual cohort. Photo via Getty Images

5 Houston energy tech companies named to Rice accelerator

seeing green

The Rice Alliance for Technology and Entrepreneurship has announced the 17 companies joining its second accelerator — and the program didn't have to venture very far for some of them.

The Rice Alliance Clean Energy Accelerator named the early- to mid-stage startups that will participate in its second annual class — five of which are based in Houston:

  • CLS Wind is developing a unique system to lift any size wind turbine component to any height using smaller-capacity cranes, an efficient, safe and economical solution to a lack of available high-capacity cranes and vessels.
  • Dsider is developing a low code solution for climate minded organizations to visualize and analyze their carbon pathways to plan, prioritize and operate sustainably and economically.
  • Emission Critical is developing carbon accounting and management software as a service to help enterprises solve end-to-end carbon footprinting with minimum effort
  • NanoTech is developing advanced materials to help businesses and individuals solve fireproofing and thermal insulation challenges with new world particles.
  • Pressure Corp is developing waste pressure power systems to help midstream gas companies solve how they reduce emissions by providing the technology, capital and expertise required to achieve their environmental, social and governance goals.

The 10-week program kicks off at the university’s Rice Alliance Energy Tech Venture Forum in September, and concludes on Demo Day on Nov. 17. While mostly virtual, the program will welcome the complete cohort to Houston three times throughout the accelerator.

The full cohort of companies — which come from seven states and four countries — has already collectively raised more than $54.5 million. Over the 10 weeks, the companies will receive support and mentorship to help them raise funding, launch pilots, win adoption into the marketplace, and more.

The 2022 cohort specializes across the spectrum of clean energy, including advanced materials, digital technology for energy, energy efficiency, energy storage, geothermal energy, hydrogen, waste heat to power, wave energy, and wind energy. The rest of the cohort includes:

  • Atargis Energy, based in Colorado, is developing an innovative twin hydrofoil-based wave energy converter technology combined with a proprietary feedback control system that combines real-time sensors, predictive algorithms and machine learning to make possible the first predictable, low-cost, utility-scale baseload electricity sourced from ocean waves for utilities and other electricity providers.
  • Based in Somerville, Massachusetts, Eden GeoPower Inc. is developing electrical reservoir stimulation technology to help geothermal, petroleum and mineral resource developers solve issues with low-permeability reservoirs by effectively increasing permeability in a way that uses less water and emits less CO2 than traditional stimulation methods.
  • FuelX has developed solid-state hydrogen power systems to help transportation manufacturers meet their customers’ growing performance requirements by using high-energy-density systems that outperform batteries and other pure hydrogen solutions. When coupled with a green hydrogen raw material, FuelX systems provide zero-carbon power.
  • GeoGen Technologies — a Canadian company — is developing a new kind of geothermal that allows oil and gas companies to convert end of life oil and gas wells to economic geothermal.
  • Durham, North Carolina-based GOLeafe uses organic materials and non-energy or capital-intensive equipment to produce graphene oxide — the world's strongest, thinnest and most conductive material — through a process that’s 10 times more cost efficient and eco-friendly using readily available materials such as hay, sugar and wood chips.
  • LiNa Energy is commercializing safe, sustainable, solid-state sodium batteries that contain no lithium or cobalt.
  • Luminescent, based in the United Kingdom, is building an isothermal expansion heat engine for waste heat recovery along gas transmission pipelines.
  • Nobel improves fuel efficiency for gas-fired power plants with drop in, reliable supersonic combustion technology.
  • Quino Energy — based in California — produces low-cost, long-lifetime aqueous organic flow batteries for grid storage applications. The charge is stored in specially designed organic molecules called quinones, which are produced from cheap chemical precursors in a proprietary, zero-waste process.
  • Viridly, based in Texas, is developing geothermal power plants with patent-pending generator technology alongside geothermal greenhouses to provide the first financially viable way to confidently deliver and scale up the development of baseload geothermal electricity.
  • Another Canadian company, Volta Technique’s compressed air storage and management technology addresses the unpredictable and ever-increasing cost of energy for large commercial and industrial electricity users while enabling decarbonization of the electricity grid through higher integration of renewable energy.
  • Wootz, another Texas company, is developing a scalable manufacturing process to produce sustainable, cost-effective, high-performance carbon nanotube materials at commercial scale to replace or enhance traditional metallic conductors.

Twelve companies participated in Class 1 of the Rice Alliance Clean Energy, which was delivered virtually last summer. The 12 startups in that inaugural class have raised a combined $6.5 million in funding, identified and launched pilots, met investors, hired staff and moved their offices to Houston.

The program is supported by founding sponsor Wells Fargo and supporters: BP, Baker Botts, Chevron, ExxonMobil, Halliburton Labs, Equinor, Microsoft, NRG, Saudi Aramco Energy Ventures, Shell Ventures, Sunnova, TotalEnergies, Tudor Pickering Holt, Canadian Consulate, TC Energy, Phillips 66, and ENI Next.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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