"Companies and stakeholders across the energy spectrum need to act together and act fast." Photo via Getty Images

Houston is home to some of the nation's largest oil and gas exploration and production firms, making it one of the world’s most important energy capitals. Growing regional support for pioneering clean tech, such as carbon capture, will help achieve the crucial transition to net zero whilst maintaining economic stability, boosting local industries and creating jobs.

According to the International Energy Agency (IEA), North America and Asia Pacific are expected to hold the largest share in carbon capture capacity. North America’s world-leading carbon capture potential comes as no surprise given the nation’s dominance in oil and gas, and ideal geology for sequestration.

The IEA’s recently published World Energy Outlook 2023 depicts a global market that is in transition. With more companies, world leaders and governments recognizing that a shift towards sustainable energy is both inevitable and transformative, the question is no longer whether we switch to clean energy, but rather how soon the transition can happen.

For every $1 in investment spending on fossil fuels globally, $1.8 is now being spent to develop clean energy, according to the IEA. Although the clean energy market has almost doubled in the past five years to reach an estimated $2.8 trillion in 2023, investment needs to hit $4.2 trillion per year by 2030 to achieve the universally shared goal of net zero. The IEA believes around 1 Gigaton of CO2 must be captured in 2030, rising to 6 Gigatons by 2050 to achieve the Net Zero Emissions by 2050 Scenario (termed NZE Scenario). This presents a tremendous opportunity for government stakeholders and the business community in Houston to turbocharge the economy and protect the planet from the impact of climate change.

While volatility around the energy market lingers, sustainable technologies remain one of the most dynamic areas of global energy investment. An essential ingredient to its success is bringing on board innovators, entrepreneurs, corporations, and financiers to ensure technology innovation is front and center in facilitating the clean energy transition.

Carbon capture technology is critical, but energy leaders and hard-to-abate industries are under pressure to move faster. To do that, the carbon capture industry must scale up its deployment and increase adoption if hard-to-abate sectors are to address the 30 percent of global CO2 emissions for which they are responsible. Governments have a pivotal role to play in providing financial, regulatory and policy incentives, facilitating a collaborative environment between financiers, hard-to-abate operators, and clean tech companies. While we are moving in the right direction, there is no room for complacency or procrastination given the short timescales for meaningful action.

Over the past several years, Carbon Clean, a global company that is revolutionizing carbon capture, has enjoyed significant expansion in North America. Following the passage of the Inflation Reduction Act (IRA) in August 2022, we saw huge interest in our modular industrial carbon capture technology almost overnight, resulting in a 64 percent increase in inquiries from the U.S. To meet this booming demand, we have opened a U.S. headquarters in Houston, and have plans to double our U.S. headcount to meet industry requirements for our scalable and cost-effective technology, CycloneCC. In short, the United States is poised to become our biggest market. Given our latest lead investor and partner is Houston-based Chevron New Energies, there is no better place than Houston to drive innovation in the country’s energy sector.

The IRA did more than just bring in new inquiries for our breakthrough technology – it also signaled to the energy sector that the federal government is getting serious about bringing emissions down. The impact of the IRA cannot be overstated, especially for the point-source carbon capture technology pioneered by Carbon Clean. While the IRA involves billions of dollars of public investment, it is set up in such a way that companies must make substantial investments first, acting as a down payment on fostering jobs and ensuring the business community is delivering ambitious climate action. The benefits are being felt locally as well – cities like Houston are at the forefront of what the IRA has to offer, taking advantage of these investments and reducing emissions.

Companies and stakeholders across the energy spectrum need to act together and act fast. With the dramatic growth required for carbon capture to have full effect, it will be essential for government, industry, and innovators to join together to concentrate on a number of projects and clusters. We are confident that with new cutting-edge technology and broad collaboration we can rapidly get the world on the right path to net zero.

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Prateek Bumb is CTO and co-founder of Carbon Clean and the principal innovator of Carbon Clean’s industrial carbon capture technologies.

This article originally ran on EnergyCapital.
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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."