Houston park accepts $10M donation for innovative ecological project

green gifting

Memorial Park's land bridges are currently under construction. Rendering courtesy of Nelson Byrd Woltz

As Houstonians have been witnessing for the past few years, Memorial Park is in the midst of a renaissance, with a game-changing land bridge in the works, the recently opened Eastern Glades, and more than $200 million in improvements slated by 2028.

Now, Houston's crown green space has received another impressive donation towards the reintroduction of the native Gulf Coast prairie, courtesy of a $10 million contribution from the The Cyvia and Melvyn Wolff Family Foundation. The massive contribution will help the park's Land Bridge and Prairie project realize its innovative goals of establishing a more resilient ecology, enhancing animal habitats, improving storm water management, and providing a beautiful, immersive and accessible experience for Park visitors, according to a press release.

"The transformation of Memorial Park is vitally important to our city and our Foundation. We are honored to be part of this incredible effort and proud to join the Kinders and others who have funded the vision for the park," donor Cyvia Wolff said in a statement. "Together, we are creating one of the largest urban prairie reclamation efforts in Texas so that Houstonians can experience a native landscape that has largely been lost."

The multi-year project aims to restore 45 acres of native prairie to the park in an area that starts at the south basin of the land bridge and extends to an area north of Memorial Dr. For the time in more than a century, the land will look as it did when Indigenous people roamed the coastal plain — long before it was farmed by European settlers or served as the ground of Camp Logan, a training area for soldiers during World War I.

Once a dominant feature of coastal Texas and Louisiana, less than 1-percent of its historic range remains, according to the Memorial Park Conservancy. Seeds from plants found along the park's railroad tracks will be added to others collected by the Nature Conservancy to enable the project's realization.

One of the project's primary benefits will be making the park more resilient during floods. The new, south prairie basin will retain more water than the parking lots, woods, and baseball fields that occupied the area previously, while the prairie's deep root system will absorb more water that would otherwise wind up overwhelming Buffalo Bayou.

Increased biodiversity means that native species will return to the park for the first time. Its proximity to the park's Bayou Wilds forest should create more opportunities for bird watchers. Park visitors will be able to experience the prairie through trails and other paths that will connect to other areas of the park.

"Cyvia and Melvyn Wolff are an important part of the fabric of Houston with their leadership in business and education. It is a true honor for us to be working with the Wolff Foundation in returning to the park's ecological and cultural roots and to, quite literally, plant the seeds for Memorial Park's future," said Shellye Arnold, president and CEO of Memorial Park Conservancy. "Through thoughtful research, design, planting, and stewardship, this project will create new places for park visitors to enjoy, grow, and learn for years to come."

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Steven Devadanam contributed to this article. This article originally ran on CultureMap.

Work has begun on a crucial part of the Land Bridge. Rendering courtesy of Nelson Byrd Woltz

Houston park moves forward on innovative land bridge project

tunnel of sustainability

Few things get local greenspace lovers more hyped than the upcoming improvements and beautification of our beloved Memorial Park — which is currently undergoing a major transformation. While many of the updates and facelifts are years off, one of the most innovative ventures has reached a new milestone in the much-anticipated Land Bridge and Prairie project.

Installation of the first tunnel arches has started as of December 9, according to the Memorial Park Conservancy. Marked by two separate, 35-foot tall mounds, the Land Bridge will serve as a major connector for park users and wildlife between the north and south sides of the park, Additionally, it will offer new gathering spaces with scenic views of Houston and the project's expansive prairie network.

Once the project is completed, vehicular traffic will traverse a new alignment of Memorial Drive via tunnels through the Land Bridge — two tunnels below each of the mounds (one for each direction of travel), according to a press release. The arch segments now being erected south of existing Memorial Drive are for the two tunnels through the eastern-most mound.

Next up will be erection of the west mound arches; all tunnels are slated for completion and open to traffic by fall of 2021.

These tunnels boast an innovative edge. While most are built through existing hillsides or below ground, the Land Bridge tunnels will be set at the same grade as the existing roadway, prior to installation of the earthwork for the mounds, per a release. The tunnels through the east and west mound measure 400 feet and 560 feet long respectively and are made up of some 620 separate panels, each of which weighs just under 50,000 pounds.

While excitement is looming, traffic on Memorial Drive is no doubt a concern. Sources at Memorial Park Conservancy assure that Memorial will remain open throughout the duration of Land Bridge and Prairie construction. Within the project area, traffic has been reduced from three lanes to two each way.

All lanes will reopen in fall 2021 once the new Memorial Drive alignment through tunnels is complete. The new road alignment with three lanes restored each way will be complete in September 2021, while the Land Bridge is slated for substantial completion by October 2022.

Meanwhile, trees removed from the Land Bridge and Prairie project area (a major concern for locals) will be relocated in areas of the park designated for reforestation, or repurposed as either compost or toewood for streambank stabilization, in keeping with the Master Plan provisions.

The new arches are being installed on Memorial Drive. Photo courtesy of Memorial Park Conservancy

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This article originally ran on CultureMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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