West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Plug and Play is opening a Sugar Land hub to accelerate startups and innovation across smart cities, energy, health, and mobility sectors. Photo courtesy of Plug and Play

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.

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Payal Patel, former director of business development at Station Houston, has joined Plug and Play as director of corporate partnerships. Courtesy of Payal Patel

Former Station Houston director joins the Plug and Play team as the program prepares for launch

New hire

Plug and Play Tech Center — a global powerhouse startup accelerator with its headquarters in Silicon Valley — has hired its first boots-on-the-ground team member for its Houston outpost.

Payal Patel, former director of business development at Station Houston, has joined Plug and Play as director of corporate partnerships. Plug and Play already has a handful of corporate partners in Houston, and Patel will be working with those organizations as well as growing the partnerships. These large companies are crucial to Plug and Play's process.

"The way we help startups advance is by helping them get connected to the largest corporations in the world so that they can run pilots with those big companies and eventually get them as customers," Patel tells InnovationMap.

Patel might be the first Houston hire since Plug and Play entered the Houston market, but it won't be the last. According to Patel, the organization will be hiring to fill a venture management-focused person, as well as someone to run operations. The most immediate hire, however, will be for an office manager, as Plug and Play is currently looking for office space. Patel says the organization should make a decision regarding its Houston office space in the coming weeks.

The accelerator program's first batch of startups will launch later this month at a private pitch event on September 17 where Plug and Play companies from around the world will pitch for Houston corporate partners and select guests. The event will act as the launch of the program's first batch, which will continue throughout the rest of the year.

Plug and Play is always evaluating startups for inclusion into their ongoing accelerator programs, Patel says, and Houston companies can express their interest in joining the program via the website.

For Patel, the new position is exciting for her — from what she will be able to accomplish but also for what it means to Houston.

"As I've gotten to know Plug and Play, what I've been most impressed with is the resources and capabilities they have," Patel says. "They've got great Fortune 500 corporate partners, they work and know the best tech startups all over the world, and they have a strong investment capability. I'm excited that those resources and capabilities are coming to Houston."

Ahead of entering the Houston market later this year, Silicon Valley's Plug and Play hosted three days of programming surrounding innovation in energy and health care. Natalie Harms/InnovationMap

Overheard: Prominent business leaders weigh in on innovation in the energy and health industries

Eavesdropping in Houston

Plug and Play, a Silicon Valley venture capital firm and accelerator program, plans to launch its operations in Houston later this year. And, in showing its commitment to the Bayou City, the organization hosted three days worth of panels, talks, and pitches at the Texas Medical Center's TMC Innovation Institute earlier this month.

Houston Innovation Week was Plug and Play's formal introduction to Houston startups and the local corporations that have the potential to support them. The programming focused on health and energy and sustainability, and the summit concluded with TMCx's Demo Day.

If you missed the event, we've hit the highlights for you by rounding up nine powerful quotes overheard throughout the week.

“Nowadays, I feel every industry is going to go through an incredible digital transformation. Even the oil and gas industry, which is very capital heavy, there’s going to be a layer of fast-moving technologies which would help the industry be more efficient. This is the crossroads where Plug and Play was born — bridging the gap between the entrepreneurs and the technologies. That changes an industry.”

— Saeed Amidi, CEO and founder of Plug and Play, says. He also shares the story of how Plug and Play got its start from a few lucky early investments to making over 150 investments a year.

“Now we have about 30 offices, and then quite frankly I realized I had forgotten about America.”

— Amidi says, announcing that Plug and Play will open five new offices across the United States in the next six months to a year.

“We’re not walking in terms of building this integrated robust innovation ecosystem, we’re sprinting in that direction.”

— Mayor Sylvester Turner says, adding that, "If there is any city that ought to be leading the way when it comes to startups, technology, and innovation, it ought to be the city of Houston."

“You have to get people to invest more. It doesn’t happen on its own. People have to see that if we invest, we’re going to get a return.”

— Mayor Turner says, calling the crowd to action. "You can't just talk about what others have done and what we have accomplished. You have to take that now, build the platform, and move into where we are going."

“One of the things you look at is it’s not the technology itself that’s going to make you win or lose, it’s what you do with it.”

— Barbara Burger, president of Chevron Technology Ventures, responding to a question about what technologies she has her eyes on. Burger continued on to say that, while she couldn't highlight any technologies in particular — it's like picking a favorite child, she's always evaluating how a new technology would help with the affordability, reliability, and lower environmental impact. "That's the game," she says.

"Management is amazing at suppressing innovation. … We can move toward just trying not to suppress it. If someone has an idea, they are safe to go through the process and raise their hand."

— Bradley Andrews, president of digital at Worley. "I think it's a change in attitude," he says about how management can evolve to advance ideas within energy companies.

“It’s easy to say that we’ll do the thing that gives us the most competitive advantage — and it’s really hard to figure out what that means and how you do that. In general, if we see something that’s out there and implemented that someone else has done, I don’t need to create an internal capability like that. I just need to go access that.”

— Doug Kushnerick, senior technology scouting and venture adviser at ExxonMobil. For Kushnerick, technology solutions that fix specific problems are easy to go after, but things that affect big picture and strategic assets are harder to figure out if they are worth implementing.

“One of our big asks from our partners from an internal perspective is really to have a champion — whether its an innovation manager or someone who really advocates these startups internally. Someone who will find the clinician and the business unit and tap the legal team.”

— Neda Amidi, global head of health and partner at Plug and Play Tech Center, responding to a question about opening up the channels of communications between startups and large companies. She adds that it's a requirement for these people to visit a Plug and Play location four to six times a year.

“What I see from a culture perspective is that it really starts with the leadership in the institution. If the people at the top in the C-suite of the institution are focused on understanding why their organization isn’t performing as well as they expect it to be and are willing to look to the outside, that’s how it starts in my mind.”

— Thomas Luby, director TMC Innovation Institute, responding to a question from the audience about large organizations that tend to be slower adaptors to new technologies.

Plug and Play is on the hunt for real estate for its Houston office. Photo by Zview/Getty Images

Exclusive: Silicon Valley startup accelerator and venture capital firm will launch its Houston program by the end of the year

Plugging in

Another accelerator with a global presence is itching to get into the Houston innovation ecosystem. California-based Plug and Play will launch its Houston accelerator program sometime in the fourth quarter of this year and is currently looking for the right location to house the company's local operations.

The organization, which has 30 locations all over the world and has made early stage investments in the likes of DropBox, PayPal, Lending Club, is hosting a series of events on June 4 to 6 at the TMC Innovation Institute. The events are free and open to the public.

"Our goal is to introduce innovation trends and disruptive technologies from Plug and Play's global ecosystem to leading corporations in Texas focused on energy, sustainability, and health care," says Omer Gozen, vice president of Plug and Play's New Materials, Food, and Sustainability Programs, in an email. "This event allows us to bring the very-best startups to Houston's backyard."

The Plug and Play programming's intent is twofold. While the talks and pitches will spark conversations within Houston's ecosystem, it will also give the organization a chance to meet face to face with Houston corporations and startups, says a spokesperson. And Houston's huge corporate presence is a major draw, says Susan Davenport, senior vice president of economic development for the Greater Houston Partnership, in a statement.

"With our large concentration of Fortune 500 companies and a broad diversity of industry, Houston is an ideal location for a platform like Plug and Play that connects startups with major corporations," says Davenport.

The city has been communicating with Plug and Play for a while and has "worked closely" with them on this new office. Representatives from the GHP and Mayor Sylvester Turner even visited Plug and Play's headquarters last year.

"Their announcement is further evidence of the growing momentum behind Houston's startup and innovation ecosystem—one that has seen the emergence of a series of accelerators and major investments in technology in less than two years," Davenport says in the statement. "That Houston is one of only a handful of locations for Plug and Play in North America indicates how important this region is to the relationship between emerging businesses and major companies."

The accelerator will run for three months twice a year with 20 startups in each cohort. The cohorts are stage-agnostic and do not require any equity or fees for the startups to participate.

Good things don't just come to those who wait. If you're wanting to get your startup in front of major corporations, you need to take matters into your own hands. Pexels

Overheard: Experts give advice for Houston startups looking for corporate partnerships

Eavesdropping in Houston

If you've ever wanted to know the best way to get your startup in front of a major corporation, according to experts from both sides of the table — here's your chance.

At the Houston Innovation Open Conference, five major players in Houston's innovation ecosystem sat on a panel and discussed startups, accelerators, and more. One question asked each panelist for their advice for corporate partnerships. Here's what they had to say.

“Go to one of our programs — even if you used to work at an oil and gas company, as a startup, you need new pathways and you need help and support and lots of love along the way.”

— Gabriella Rowe, CEO of Station Houston. Even with a Houston business background, there's strength in numbers, she says.

“Keep your identity along the way.”

— Haibin Xu, regional manager of Shell Research Connect & GameChanger US and Canada. From the corporate side of things. Xu said sometimes the Shells of the world can't help you — find the right company that best aligns with your startup.

“Do your research. … And have a clear value proposition, and put it on the table.”

— Wade Bitaraf, head of energy and sustainability practice at Plug and Play. Preparation and research is extremely important before you meet with any potential corporate partners.

“Find a community to join … and don’t limit yourself to what you think is your industry.”

— Brad True, managing director of The Cannon and Cannon Ventures. True gave an example of a Cannon company that found success outside the industry they thought they were confined to.

“You have to find the pathways that are going to make it as easy as possible.”

— Brian Richards, innovation lead and managing director at Accenture. Richards emphasized that startups can go bankrupt waiting for something formal from a big corporation.

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

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