From new board members at Houston Exponential to startups receiving funding, here are the latest short stories of Houston innovation. Photo by Zview/Getty Images

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, a startup snags funding from a new corporate venture group, a blockchain startup gets major kudos, CTV's latest investment, and more.

HX names newest board members

HX has five more members of its board. Photo courtesy

Houston Exponential has announced five new members to its governing board. Joining the group is:

  • Stephanie Campbell, managing director of the Houston Angel Network and general partner at The Artemis Fund
  • Martha Castex-Tatum, Houston City Council member
  • Gordon Daugherty, co-founder and president of Capital Factory
  • Emily Keeton, CFO of Mercato and co-founder of Station Houston
  • Roberto Moctezuma, founder and CEO of Fractal River
The board is chaired by Barbara Burger of Chevron and Chevron Technology Ventures. She will continue on as chair until the end of next year, when Blair Garrou of Mercury Fund will take over.

New corporate venture fund makes first investment

Houston-based SmartAC emerged from stealth mode this summer. Photo courtesy of smartac.com

Pinnacle Ventures, a corporate venture fund created by Pinnacle based just outside of Houston in Pasadena, announced the company has invested in Houston-based SmartAC.com, a member-based technology platform that monitors the health of air conditioning systems.

The deal is Pinnacle Ventures' first investment and will help SmartAC.com expand their service offerings to homeowners and top-level HVAC service providers.

"We are excited to have Pinnacle Ventures invest in our company and to have Ryan Sitton, founder and CEO of Pinnacle, join our board," says Josh Teekell, founder and CEO of SmartAC.com, in a news release. "The capital provided by Pinnacle Ventures will help us accelerate the growth required to meet our customer demand, which has scaled quickly since our launch in June.

"Additionally, this capital will help us power a new residential connected service economy for a $30 billion industry while offering our service partners a way to increase loyalty through improved transparency and customer experience," Teekell continues. "We're very much aligned with Pinnacle Ventures' focus on improving reliability through innovation and are confident that this investment will help us support our end users."

Data Gumbo recognized as an innovative blockchain company

CB Insights ranked 50 blockchain companies and one Houston startup made the cut. Photo via CB Insights

CB Insights released its inaugural Blockchain 50 ranking and named Houston-based Data Gumbo among the top blockchain companies in the world.

"The Blockchain 50, which we've created in conjunction with Blockdata, was born out of a desire to reduce that uncertainty and recognize the pioneering companies using the blockchain," says CB Insights CEO Anand Sanwal in the study. "This inaugural class of the Blockchain 50 is tackling a range of use cases across trade finance, capital markets, exchanges and more and are being used by banks, governments and major retailers."

Combined, the 50 companies included in the ranking have raised over $3 billion across 113 deals since 2017.

"Being named to this CB Insights' list is an honor and testament to the power of Data Gumbo's blockchain network GumboNet," says Andrew Bruce, CEO and Founder, of Data Gumbo in a news release. "Our smart contracts enable companies to leverage blockchain technology across the global business infrastructure to capture critical cost savings and value, forging a new foundation for commercial transactions: one based on trust, transparency, speed and visibility."

Currux Vision is deploying its technology in California

The Houston company's technology has been tested in California. Photo via currux.vision

Houston-based Currux Vision, which uses infra-tech artificial intelligence and machine learning solutions for smart city infrastructure, has conducted testing with the city of San Jose, California, and its department of transportation.

According to the tests, Currux Vision's SmartCity ITS can operate at 99 percent accuracy in the city. Moreover, Currux Vision can achieve high resolution results with older legacy digital and analog camera systems that offer lower resolution. Testing included but was not limited to vehicle detection and classification, turning movement counts, pedestrian counts, bicycle discrimination, stopped vehicles, and speeding, according to a press release.

"Increasing urbanization, traffic, mode shift, and increasing focus on safety drive the urgent need for a next-generation traffic management solution like our SmartCity ITS," says Alex Colosivschi, founder and CEO of Currux Vision, in the release. "We believe that efficient mobility and being able to do more with less creates economic opportunities, enables trade, improves quality of life, and facilitates access to markets and services effectively leveraging resources. ... We are happy to have worked with a great partner like San José's Department of Transportation to prove these transportation solutions."

Chevron Technology Ventures invests in software company

Chevron Technology Ventures, led by Barbara Burger, has announced its latest investment. Courtesy of CTV

Houston-based Chevron Technology Ventures has invested in a Denver-based container platform company's latest round. Nubix today announced it has closed $2.7 million in seed financing led by Tuscan Management with strategic investment from Chevron Technology Ventures, in addition to participation from other new investors.

"Businesses worldwide are investing in digital transformation initiatives with IoT-based solutions," says Rachel Taylor, Nubix co-founder and CEO, in a news release. "Our unique innovation in container and services technology enables unprecedented agility and safety when building, deploying and managing applications at the edge.

"We're delivering on digital transformation's requirements for agile compute at the edge, empowering organizations to analyze data in real-time where the data is actually created. This is a massive market opportunity for Nubix and we look forward to working hand-in-hand with our new investors as we drive agility and intelligence to the edge."

Golden Section Ventures invests in Austin startup

GSV has invested in Accelerist's impact-driven software. Image via accelerist.com

Austin-based Accelerist Inc. raised a $1 million investment round led by Houston-based Golden Section Ventures to catalyze the company's growth plans. Accelerist specializes in social impact partnership technology that nonprofits use to prospect, screen, access and measure the efficacy of their relationships with each other.

"We are very impressed with what Brittany (Hill, CEO and founder) and her team have built and are excited to join the journey," says Dougal Cameron, General Partner at GSV. "We are confident that Accelerist can be the standard of excellence for social impact partnership technology. This solution is more needed than ever."

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.