Podcast: Here's what innovators think of Houston's innovation ecosystem

HOUSTON INNOVATORS PODCAST EPISODE 175

This week's episode of the Houston Innovators Podcast features five mini interviews with Houston innovators. Photos courtesy

It's the fourth year for Houston Tech Rodeo — a four-day event that takes over Houston's innovation ecosystem — and the programming is in full swing.

The week, put on by Houston Exponential, shines a spotlight on Houston innovators, investors, startup development organizations, and more and invites everyone to the table to learn more about the goings on within Houston's business community and connect with fellow Houstonians.

In honor of the week, today's edition of the Houston Innovators Podcast is a bit different. Rather than sit down with one Houston innovator, I got to chat briefly with five movers and shakers within Houston tech: Damyanna Cooke of Boozed and the Black Founders Network,Joshua Taylor of Capital Factory and the Black Founders Network,LaGina Harris of The US Space,Brandy Guidry of the Pearland Innovation Hub, and Chad Spensky of Allthenticate.

I took the opportunity to ask each of them about how they have engaged with the Houston innovation ecosystem and how they've seen it evolve and grow. Each of them also told me what they thought the city still needed to work on as well as its greatest asset to founders and the greater innovation community.

Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


The Pearland Innovation Hub celebrates its launch this week. Photo via pearlandedc.com

Pearland to open innovation-focused hub to support local entrepreneurs

coming soon

Entrepreneurs in the Pearland area have a new resource to help them grow their businesses.

The Pearland Economic Development Corp. has launched the Pearland Innovation Hub, aimed at connecting small businesses with programs and services that are designed to contribute to their success.

The Pearland Innovation Hub is managed through a partnership between the Pearland Economic Development Corp. and The Cannon, a Houston-area business networking community for entrepreneurs, investors, and corporate innovators. For now, the hub does not officially have a physical space. The hub is welcoming the local community to their launch party Thursday, May 19, at BAKFISH Brewing.

The Cannon hired Brandy Guidry to run the Pearland hub. She has more than 17 years of experience in business operations; engineering; technical marketing; innovation; and strategic planning, project, and program management.

Among the hub’s offerings are business-plan competitions, business coaching, networking, and programs.

Guidry’s office is at the Pearland Chamber of Commerce. “We can have small gatherings here,” she says. “Our focus is to have as many events at local venues to help promote and patronize the local business owners.”

Pearland Mayor Kevin Cole says in a news release that the hub will “serve to establish Pearland as a community known for innovation and entrepreneurship and where emerging companies want to locate.”

“The Pearland Innovation Hub is a groundbreaking initiative to support existing and aspiring small business owners,” Guidry adds.

A launch party for the Pearland Innovation Hub is scheduled for 5 pm May 19 at Pearland’s Bakfish Brewing Co., 1231 Broadway St.

Pearland Prosperity’s Community Strategic Plan recommended establishment of a hub for entrepreneurship and small business assistance. In April 2021, the economic development corporation’s board set in motion the creation of the hub. Seven months later, the Pearland City Council approved a three-year, $927,000 contract with The Cannon to operate the hub.

Members of the hub’s advisory board are:

  • Matt Buchanan, president of the Pearland Economic Development Corp.
  • Mona Chavarria, owner of A&A Cleaning.
  • Bill Jackson, founder and CEO of Base Pair Biotechnologies.
  • Jim Johnson, president and CEO of the Pearland Chamber of Commerce.
  • Randeep Nambiar, a board member of the Pearland Economic Development Corp.
  • HR consultant Ann Strouhal.

During the hub’s first year or two, it’ll be run through the economic development corporation. But the plan is to eventually transition the hub to its own nonprofit organization that will enter a contractual relationship with the economic development corporation.

Other than the Pearland Economic Development Corp. and The Cannon, the hub’s partners include the City of Pearland, the Pearland Chamber of Commerce, and San Jacinto Community College’s Small Business Development Center.

Brandy Guidry is the Pearland Navigator with The Cannon. Photo via pearlandinnovationhub.com

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.