Chevron taps startup for accelerator, nonprofit calls for diverse founders, and more Houston news

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A Texas startup joins another Houston accelerator — and more Houston innovation news. Photo via Getty Images

Houston's summer has been heating up in terms of innovation news, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, a Houston accelerator program taps an Austin energy tech startup, a health tech company names a new C-level exec, and more.

Houston-founded startup raises $26M, names new CEO

Spruce has fresh funding and a new CEO. Photo via GetSpruce.com

Houston-founded multifamily service provider Spruce has raised a $26 million series B round of funding. Additionally, the company has named seasoned technology executive and board member Steven Pho as CEO. His previous experience includes Favor Delivery and RetailMeNot. Former CEO and founder, Ben Johnson, will transition to president.

“For the past two years, I’ve been able to guide Spruce as a board member and am honored to continue to do that as CEO,” says Pho in a news release. “Ben’s vision for Spruce ensured the company’s incredible growth to date, as well as the outsized positive impact on local economies and small businesses Spruce partners with across the country. I am excited to continue to partner with him as he transitions to President of the company. ”

The series B round was led by Sweat Equity Partners, with participation from SoftBank Corp., Mercury Fund, Fitz Gate Ventures, Seamless Capital, Raven One Ventures, and New Age Ventures. The funding will be used to grow the company's team to support expansion. Spruce reportedly plans to nearly double its headcount.

“We believe Spruce has established the right formula for working with local businesses, consumers, and rental properties alike,” says Manish Narula of SoftBank Corp. “We are looking forward to Spruce’s continued growth as it scales with this latest investment round.”

Spruce has raised $40 million to date, including its $8 million series A, which was led by Houston-based Mercury Fund in 2020. The company, which was founded as Apartment Butler, rebranded and relocated its HQ to Austin a couple years ago.

Texas tech startup joins Chevron Technology Ventures Catalyst Program

Houston startup aims to prepare the energy industry's future workforceFrom Rex Tillerson's thoughts on leadership and politics to Houston's role in the low-carbon energy movement, check out these powerful quotes from the 2020 KPMG Global Energy Conference. Getty Images

An innovative Austin company has doubled down on its acceleration and incubation activity in Houston.

Parasanti Inc. was selected to participate in the Houston-based Chevron Technology Ventures Catalyst Program. The company is a member of Greentown Houston and participated in Halliburton Labs. The company's edge computing technology provides secure solutions for remote work — such as off-the-grid oilfield operations.

Through CTV's Catalyst Program, which was founded in 2017 to help mature early-stage technology destined to impact the energy industry, Parasanti be tasked with further developing its software and expand into new projects.

“Parasanti is honored to receive support from a global energy technology leader like Chevron through this program,” says Carrie Horazeck, president of Parasanti’s commercial division, in a news release. “The CTV team has been incredibly helpful as we adapt our technology for the advanced energy solutions market. This program further demonstrates Chevron’s commitment to enabling the energy transition through technological advancement.”

Houston founders can apply for $100,000

Calling all diverse founders in Houston. Photo via Getty Images

Houston founders have until July 25 to apply for Founders First CDC's Job Creators Quest Grant, which will dole out $100,000 to support minority and underrepresented business owners throughout the state of Texas. The nonprofit is looking for Texas companies that:

  • are diverse-led (Black, indigenous, a person of color, LGBTQIA+, military veteran, a woman or located in a low to moderate income area)
  • employ two to 20 people
  • are located in the north, central east, or south Texas regions
  • have annual revenues between $100,000 to $3 million

The grant program was established to help business owners create premium wage jobs and reward diverse-led businesses throughout the state of Texas. Since its launch in early 2021, Founders First CDC has awarded more than $400,000 to minority and underserved business owners throughout the United States.

“With the rising cost of living, it can be challenging for families let alone business owners to stay afloat, particularly when it costs them more to provide goods and services for their consumers,” says Shaylon Scott, executive director of Founders First, in a news release. “We are happy to be able to invest money and resources in hard working business owners throughout Texas to help them thrive, even during uncertain economic times. Investing in diverse entrepreneurs is not only an impactful way to create jobs but is a pivotal way to close the general wealth gap in underserved communities.”

Qualified business owners, particularly those in the Dallas-Ft. Worth, Houston, Austin, and San Antonio markets can learn more and apply online.

Houston tech startup snags military award

This online learning platform just partnered up with a government entity. Photo via Getty Images

Houston-based UpBrainery Technologies, an online learning platform, received an award from the Department of Defense Education Activity as the premiere provider of Career Technology Education for 52 military middle Schools across the world. CTE provides middle school students with critical academic and technical skills, knowledge, and training.

"UpBrainery's skills-based training is delivered through the proprietary artificial intelligence-based technology, BrainLab," the company reports in a news release. "The blend of cutting-edge technology and skills training content provides an engaging experience for students delivered through TikTok-style videos, gamified learning, and augmented reality."

The agreement builds upon DODEA's vision of educating, engaging, and empowering military-connected student in order to ensure that "all school-aged children of military families are provided a world-class education that prepares them for post-secondary education and/or career success," the release continues.

Specific details on the partnership were not released.

Houston oncology company names new C-suite leader

Aravive Inc. has a new chief medical officer. Photo via Getty Images

A Houston-based late clinical-stage oncology company has a new C-level exec.

Aravive Inc. (Nasdaq: ARAV), which is developing targeted therapeutics to treat metastatic disease, announced its new chief medical officer, Dr. Robert B. Geller. A medical oncologist with over 30 years of drug development experience, Geller will lead all aspects of clinical and medical affairs, including commercialization preparedness and launch of novel therapeutics, according to a news release.

“I feel very fortunate and proud that I am able to join Aravive at this critical juncture, as the company nears key value inflection points,” says Geller in the release. “As a medical oncologist, I have devoted my career to caring for patients, and developing and commercializing new therapies for cancer patients. Based upon the clinical data to date on batiraxcept, I am convinced that batiraxcept has the potential to meet the high unmet medical needs of patients with advanced cancers, and potentially become a best-in-class medicine across a range of tumors, including ovarian, renal and pancreatic cancer, which require new treatment approaches.”

Geller was most recently senior vice president of medical affairs at California-based Coherus Biosciences. He's authored over 200 publications and abstracts and has served as reviewer for numerous medical journals.

Halliburton Labs has named its newest cohort — and opened applications for the next one. Photo courtesy of Halliburton

Houston clean energy lab names 4 new companies to program

new to the labs

Halliburton Labs has doubled the number of clean energy companies that are operating out of its facilities with the addition of its second cohort.

Four companies have been selected for the program, joining four existing member companies of Halliburton Labs, which originally launched last summer. The companies recently announced to the incubator are Alumina Energy, Ionada, Parasanti, and SurgePower Materials.

"We are excited to support and collaborate with this group of early-stage, clean energy companies as they continue their commercialization journey," says Dale Winger, managing director of Halliburton Labs, in a news release. "Each has demonstrated a commitment to accelerating their technologies, and we are eager to help them innovate, develop and scale each company."

The new companies join existing labs members Nanotech Inc, Enexor BioEnergy, Momentum Technologies, and OCO Inc. Nanotech was the first company to join the labs in August 2020, while the other three were added in February.

With the announcement of the new cohort, Halliburton is now accepting applications for its third cohort. Interested companies can apply via the website, and submissions are due by September 3, 2021.

Alumina Energy

Focusing on providing zero-carbon heat and power solutions, Santa Monica, California-based Alumina Energy has created a patented packed bed thermal energy storage technology that can make renewable energy resources a more reliable and cost competitive source of heat and power.

"We are very excited to join Halliburton Labs' cleantech accelerator program and collaborate with their experienced team to advance cleaner, affordable energy," says Sasha Braun Diamont, founder and CEO of Alumina Energy, in the release.

Ionada

Ionada is based in Ontario, Canada, and also has offices in London and Germany. The company has developed an exhaust gas cleaning systems that's designed to reduce emissions from the marine and power generation industries.

"We are receiving tremendous interest from industrial emitters around the world for modular carbon capture systems. Halliburton Labs' engineering, supply chain expertise and global network provide the ideal launching platform for us to scale our business to meet demand," says Edoardo Panziera, CEO of Ionada, in the release.

Parasanti

Headquartered in Austin, Parasanti is a tech company with software and hardware applications geared toward streaming analytics and production machine learning to enhance data analytics,

"Parasanti could not be more honored to be a part of the Halliburton Labs accelerator. With the domain expertise and wealth of knowledge that Haliburton Labs possesses, this accelerator will position Parasanti to leverage our edge hardware and software technologies to enable new artificial intelligence and machine learning solutions in the energy space," says Parasanti co-founders James Hancock and Joshua Seagroves in the release.

SurgePower Materials

San Marcos-based SurgePower Materials has developed a way to produce high-purity graphene from an abundant renewable raw material — a process that will allow for producing concrete, electronics, renewable energy, and batteries in a more sustainable way.

"Our goal is to make SurgePower Materials the key enabler of the forthcoming graphene age with plant-based graphene as an essential component of many new technologies. Our strategic collaboration with Halliburton Labs allows us to leverage their world-class engineering expertise to rapidly scale our production and accelerate the adoption of new graphene-based solutions," says Dr. Michael Opoku, CEO of SurgePower Materials, in the release.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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