Ventilator designed by Rice University team gets FDA approval

in the bag

A Rice University team of engineers designed a low-cost ventilator, and now the device, which has been picked up for manufacturing, has received approval from the FDA. Photo courtesy of Jeff Fitlow/Rice University

A ventilator that was designed by a team at Rice University has received Emergency Use Authorization from the U.S. Food and Drug Administration amid the COVID-19 pandemic.

The ApolloBVM was worked on March by students at Rice's Brown School of Engineering's Oshman Engineering Design Kitchen, or OEDK. The open-source plans were shared online so that those in need could have access to the life-saving technology. Since its upload, the ApolloBVM design has been downloaded by almost 3,000 registered participants in 115 countries.

"The COVID-19 pandemic pushed staff, students and clinical partners to complete a novel design for the ApolloBVM in the weeks following the initial local cases," says Maria Oden, a teaching professor of bioengineering at Rice and director of the OEDK, in the press release. "We are thrilled that the device has received FDA Emergency Use Authorization."

While development began in 2018 with a Houston emergency physician, Rohith Malya, Houston manufacturer Stewart & Stevenson Healthcare Technologies LLC, a subsidiary of Kirby Corporation that licensed ApolloBVM in April, has worked with the team to further manufacture the device into what it is today.

An enhanced version of the bag valve mask-based ventilator designed by Rice University engineers has won federal approval as an emergency resuscitator for use during the COVID-19 pandemic. Photo courtesy of Stewart & Stevenson

The Rice team worked out of OEDK throughout the spring and Stewart & Stevenson joined to support the effort along with manufacturing plants in Oklahoma City and Houston.

"The FDA authorization represents an important milestone achievement for the Apollo ABVM program," says Joe Reniers, president of Kirby Distribution and Services, in the release. "We can now commence manufacturing and distribution of this low-cost device to the front lines, providing health care professionals with a sturdy and portable ventilation device for patients during the COVID-19 pandemic."

Reniers continues, "It is a testimony to the flexibility of our people and our manufacturing facilities that we are able to readily utilize operations to support COVID-19 related need."

The device's name was selected as a tribute to Rice's history with NASA and President John F. Kennedy's now-famous speech kicking off the nation's efforts to go to the moon. It's meaningful to Matthew Wettergreen, one of the members of the design team.

"When a crisis hits, we use our skills to contribute solutions," Wettergreen previously told CultureMap. "If you can help, you should, and I'm proud that we're responding to the call."
A Houston-based team of scientists and students have developed a low-cost ventilator. Photo courtesy of Rice University

Rice University students and staff team up with Canadian company to make low-cost ventilators

hi, tech

As the COVID-19 case numbers continue to grow, hospitals around the world are either experiencing or expecting a shortage of ventilation units. In Houston, a team of students and staff at Rice University have designed a solution.

Along with Canadian global health design firm, Metric Technologies, the Rice team has developed an automated bag valve mask ventilator that can be crafted for less than $300. Moreover, the team expects to share the designs so that these low-cost machines can be produced everywhere.

The project is being called Take a Breather and was inspired by an early prototype that a group of engineering seniors developed in 2019 at Rice's Brown School of Engineering's Oshman Engineering Design Kitchen, or OEDK. The idea was to take a bag valve mask, which medical professionals use manually by squeezing with their hands, and create a device that can instead compress the bag automatically.

The parts of the device are largely created via 3D printing and laser cut, according to a press release from Rice, and only took around a week to prototype. While the original project was created to help emergency medicine professionals using a manual ventilator, the device is very relevant in the current coronavirus crisis.

"The immediate goal is a device that works well enough to keep noncritical COVID-19 patients stable and frees up larger ventilators for more critical patients," says Amy Kavalewitz, executive director of the OEDK, in the release.

As principal at Metric Technologies, Dr. Rohith Malya, who is assistant professor of emergency medicine at Baylor College of Medicine and an adjunct assistant professor of bioengineering at Rice, saw the growing need for for automated ventilator masks in emergency medicine.

"This is a clinician-informed end-to-end design that repurposes the existing BVM global inventory toward widespread and safe access to mechanical ventilation," Malya says in the release.

According to Malya, more than 100 million bag valve masks are produced annually. The designed device, which can work with these bags, has been named the ApolloBVM — a nod to when President John F. Kennedy announced from the Rice campus that it was his mission to get America to the moon.

"This project appeals to our ingenuity, it's a Rice-based project and it's for all of humanity," he says in the release. "And we're on an urgent timescale. We decided to throw it all on the table and see how far we go."
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Houston's fund of funds announces 2 new investments

money moves

The HX Venture Fund, which invests in out-of-town venture capital funds that have their eyes on Houston startups, has grown its portfolio.

The fund of funds now has a portfolio of 10 VCs from across the country, across industries, and across startup stages. According to a recent announcement, the HX Venture Fund has invested in New York-based Greycroft Venture Partners and Washington D.C.-based Revolution Ventures. The announcement also included Boston-based Material Impact and San Francisco-based venBio Global Strategic Fund, however those had been previously reported by InnovationMap.

"We are delighted to partner with the general partners of Greycroft Venture Partners, Material Impact, Revolution Ventures, and venBio Global Strategic Fund," says Sandy Guitar, managing director of HX Venture Fund, in the release. "With their proven expertise and exceptional track records, we are excited to integrate them into Houston networks and not only give them access to the Fund's innovative corporate limited partners, but also harness their knowledge to empower Houston entrepreneurs."

These four VC funds join six others that HXVF has invested in: Austin-based LiveOak Venture Partners and Next Coast Ventures, Washington D.C.-based Updata Partners, Chicago-based Baird Capital, and Boston-based .406 Ventures and OpenView Venture Partners.

"The receptivity of the HX Venture Fund model has exceeded all our expectations. Since early 2019, over 217 venture capital funds across the U.S. have expressed definitive interest in participating in our model," says Guillermo Borda, managing director of HX Venture Fund, in the release.

"It is especially noteworthy that collectively, the ten funds selected for HX Venture Fund's portfolio have $3.7 billion in committed capital in their funds to be invested with Houston on their investment radar," Borda adds. "This is at a time that provides compelling investment opportunities in the economic cycle. This is an exciting time for Houston entrepreneurs and our innovation ecosystem."

Guitar previously told InnovationMap that she's looking to curate a portfolio of VCs that is diverse in industries and stage. Additionally, before investing in a VC, the HX Venture Fund looks for an interest in investing into Houston startups. The hope is that, while not required, the HXVF portfolio funds invest in a Houston startup down the road. Earlier this year, Houston-based Liongard became the fund of funds' first example of that.

"The innovation and talent in Houston are best-in-class; we want to be investing there," says Tige Savage, managing partner at Revolution Ventures, in the release.

Rice University rises to top of Texas schools in prestigious U.S. News & World Report ranking

Head of class

Rice University continues to rise in national surveys. The latest: U.S. News & World Report's 2021 Best Colleges, released September 14, anoints Rice as the best university in Texas. The prestigious Houston school — dubbed the "Ivy League of the South" — ranks No. 16 among national universities, up one spot from last year.

This is in step with last year's U.S. News & World Report's Best Colleges list, which also named Rice the best university in Texas.

The trusted report compared more than 1,400 undergraduate institutions across 17 measures of "academic quality" this year. Acknowledging the ongoing impact of the coronavirus pandemic on students and schools, the publication made several updates to its methodology, notes a release.

For 2021, U.S. News added two new metrics to measure student debt. It also increased the weight of the outcome category, which measures graduation rates, retention rates, and social mobility, and reduced the weights for standardized test scores, high school class standing, and alumni giving. And, for the very first time, the report ranks test-blind schools (those that don't require an SAT or ACT score for admission).

"The pandemic has affected students across the country, canceling commencement ceremonies and switching classes from in person to remote," said Kim Castro, editor and chief content officer, in a release. "Whether students have slightly altered their college plans or changed them entirely, it remains our mission to continue providing students and their families with the tools they need to help find the right school for them."

Now, on to the rankings. Here's how Rice scores in the prestigious report:

  • No. 6 in Best Undergraduate Teaching
  • No. 8 in Best Value Schools
  • No. 18 in Most Innovative Schools (tie)
  • No. 224 in Top Performers on Social Mobility (tie)
  • No. 19 in Best Undergraduate Engineering Programs (tie)

For 2021, the University of Texas at Austin ranks No. 42 nationally, up a significant six spots from 2020. It's also the school's highest ranking on the report since 1985, touts a news release from the university. Among the country's public universities, UT Austin climbed four spots from the previous year, landing at No. 13.

As for Texas' other top schools, Southern Methodist University and Texas A&M University are tied at No. 66 nationwide, while Baylor University and Texas Christian University rank No. 76 and No. 80, respectively.

The lofty U.S. News & World Report ranking is just the latest in accolades for the Owls. Rice was recently named the seventh best college in the U.S. and the best college in Texas by Niche.com.

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This article originally ran on CultureMap.

Trusted Houston bank identifies 4 coronavirus-related scams you need to know

On Your Side

As the COVID-19 pandemic has grown, so has the confidence of fraudsters who are hoping to scam people out of money. A large portion of our everyday lives have moved online and onto our phones, so it's more important than ever that you know what common tricks to watch out for.

Texas Citizens Bank continually looks out for its customers, creating tip sheets that help everyone become more educated about different types of fraud, from email scammers to debit and credit card crooks.

Here, they outline four common COVID-19 schemes that are making the rounds:

1. Fake offers of info, supplies, or payments
If it sounds official and mentions COVID-19 or the CARES Act, it must be legit, right? Wrong. These websites, mobile apps, and emails with links or attachments are entirely fake. Do not open, click, or download anything sent to you — instead, go directly to the official website on your own to find the info.

2. Someone posing as a doctor or ill family member
If you get a call claiming that someone you love is ill with coronavirus — and too ill to come to the phone, at that — and needs money for treatment, don't believe it. Hang up immediately and call that family member yourself.

3. Claims that your Social Security benefits are suspended
If you receive a letter or email, no matter how official-looking, that says your SSA benefits have been suspended due to COVID-19, know that it's not true. The SSA has not suspended or reduced any benefits, pandemic or not. Be sure to report this scam to the government here.

4. Offers of COVID-19 tests and vaccines
If someone is claiming they can send coronavirus tests directly to your house, they're lying. If they claim they can do the same with a vaccine, they're really lying. You can only obtain tests at hospitals, urgent care facilities, and your doctor's office, and we're still waiting on a reliable vaccine to be approved. Until then, be extra careful about who you believe.

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Texas Citizens Bank is an independently owned, FDIC-insured bank that specializes in Houston's small and medium-sized business owners. If you have questions about financial options during coronavirus or how to keep your money safe, contact a TCB banker today at 713-948-5700.

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