Houston cancer-fighting organization launches center to support early clinical trials

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The new center is specifically designed to allow patients to be on the cutting edge of testing brand-new therapies that could save their lives.

Cancer treatment in Houston just became even more promising — and forward-thinking.

Phase 1 clinical trials are necessary to prove the efficacy in humans of treatments that have appeared promising in lab trials. In the name of cancer-fighting innovation, Baylor College of Medicine’s Dan L. Duncan Comprehensive Cancer Center has launched the Albert and Margaret Alkek Foundation Center for Experimental Therapeutics.

The new center is specifically designed to allow patients to be on the cutting edge of testing brand-new therapies that could save their lives.

“Clinical trials are critical for advancing the field of oncology and improving outcomes for cancer patients. Phase 1 trials are the first step in bringing innovative therapies to the clinic,” says Dr. Benjamin Musher, Barry S. Smith endowed professor at Baylor and medical director of medical oncology at the Duncan Cancer Center McNair Campus, in a news release. “Our new program will build on the success of previous phase 1 trials at Baylor and provide robust infrastructure to offer more clinical trial opportunities to our patients.”

The Alkek Foundation Center’s team practices across all specialty areas, allowing a broad swath of the Cancer Center’s patients to take part and to continue to receive care from the sub-specialty doctors they know and trust. And even if they aren’t already being treated at Baylor, physicians from outside Baylor can refer patients to the program through a smooth process.

“We are excited to offer novel research treatment options to our cancer patients at our state-of-the-art unit,” says Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center and senior associate dean of cancer programs at Baylor. “This program will increase the scope of our research while giving the cancer patients in our community access to first in human and cutting-edge clinical trials.”

Patients will be treated at Duncan Cancer Center’s clinical home, Baylor St. Luke’s Medical Center’s O’Quinn Medical Tower at the McNair Campus. As interim dean of research and dean of the Graduate School of Biomedical Sciences at Baylor, Carolyn Smith says, with the new center, Baylor is “advancing medicine by taking innovations made in the lab and moving them to the bedside.”

The debut trial to take place at the center enrolled its first patient this month. It will test a novel therapy that targets a mutation commonly found in pancreatic and colorectal cancers.

“Phase 1 oncology clinical trials provide patients early access to cutting-edge therapeutics and immunotherapies that are not widely available. Patients in these trials are often selected because their tumors have a molecular feature that is targeted by these therapies,” says Dr. S. Gail Eckhardt, who is Baylor’s Albert and Margaret Alkek endowed chair and serves as associate dean for experimental therapeutics at Baylor and associate director of translational research at the Duncan Cancer Center.

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Play it back: Houston therapeutics co. sees momentum with expanded treatment opportunities

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It's been a busy summer for Houston-based Coya Therapeutics, a clinical-stage biotech company that's creating revolutionary treatments for neurodegenerative diseases like Alzheimer’s, Parkinson’s, and ALS.

In July, Coya announced that has expanded its collaboration with Houston Methodist Research Institute, or HMRI. The publicly traded company also announced fresh funding from the Johnson Center for Cellular Therapeutics.

Last month, Coya reported that it has expanded its treatment research to see how GLP-1 drugs — a trending drug for weight loss — can enhance the effects of its proprietary therapeutics. By combining the medicines, Howard Berman, co-founder and CEO of Coya Therapeutics, says he thinks Coya can better treat these complex immune-based diseases.

Berman joined the Houston Innovators Podcast in April of 2023 to discuss taking Coya public and his passion for the company's mission.

"I was interested in what I could do for my dad," Berman says on the Houston Innovators Podcast, explaining how he took the meeting with Dr. Stanley Appel, who then presented him with some of his research. "By slide five my jaw had hit the ground.

"He had shown that he could stop the progression in one of his early trials of ALS," Berman says.

Berman shares more of the Coya Therapeutics story on the podcast, as well as how he sees Houston's potential as an emerging hub for biotech.

"The next number of years as we develop this therapeutic regimen for ALS, we have the potential to transform Houston into something more than it is currently," he says. "Our success will be the city's success."

Diversity-focused sports tech accelerator opens applications to Houston innovators for the first time

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A global organization has announced it's opening applications to its equity-focused sports tech accelerator to Houston founders for the first time.

Thanks to a collaboration with Impact Hub and Black Ambition, the adidas Community Lab has expanded its footprint and is now accepting applicants from new markets, including Houston, Toronto, Los Angeles, Atlanta, and New York, for its 2024-2025 cohort.

The initiative, which has been running for three years, has a goal of supporting Black and Latino/a/e founders with mentorship, pitch training, event programming, and networking. The eight-month program also has $75,000 in grant funding to dole out to participants as well.

“As Community Lab enters its third year, we are thrilled to cultivate a larger cohort of social entrepreneurs who share our vision of removing barriers to accessing sport for the communities we collectively serve,” Ayesha Martin, senior director of adidas Purpose, says in a news release.

Both the global organization of Impact Hub and the local group, Impact Hub Houston, are involved in the collaboration.

“Impact Hub is thrilled to partner and support this third iteration of adidas Community Lab, empowering visionary leaders who are advancing SDG3 —Good Health and Wellbeing — and SDG10 — Reduced Inequalities," Michelle Avalos, co-founder of Impact Hub Houston, adds. Together, we’re helping entrepreneurs create equitable access to sports and foster healthier, more inclusive communities for all."

Applications are open online now until September 23.

Founded by Pharrell Williams, Black Ambition will also collaborate with the program this year on key programing sessions. The organization invests funding and resources into Black and Hispanic entrepreneur-founded startups.

"Black Ambition was founded to create the space, bespoke opportunities and relationships needed for underrepresented founders to excel, uninterrupted. We are excited to partner with adidas Purpose to extend elements of our renowned, global founder support model to social impact entrepreneurs positively transforming their communities through sports and wellness," says Jermeen Sherman, managing director at Black Ambition.

City of Houston grants $100,000 to 10 innovative arts organizations

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Ten Houston individuals and nonprofits are beneficiaries of grants totaling $100,000 for efforts to furthers cultural tourism and resilience throughout the City of Houston.

The Mayor’s Office of Cultural Affairs (MOCA) awarded the funds through the Initiative, a competitive grant program administered by Houston Arts Alliance (HAA) and funded by a portion of the city’s Hotel Occupancy Tax.

The application period is open three times annually and grant funding falls into three categories: Art + Neighborhood Cultural Destinations, Art + Disaster Resilience Awareness, and Art + Conference Tourism.

Here is a look at the winners and the projects that will be created with these grants.

Art + Conference Tourism

Contemporary Arts Museum Houston
This week, from September 16-19, the museum, in partnership with Houston Freedmen’s Town Conservancy (HFTC) and artist Theaster Gates, hosts Houston’s edition of the renowned Black Artists Retreat (B.A.R). The initiative explores the concept of “Black Land Ownership and Space: Black Stabilization and Determination." The four-day event brings together speakers, panelists, and experts from Houston and across the country to elevate and inspire the brain trust in local Black and BIPOC artists, creatives, and intellectuals. Programming occurs in Houston Freedmen’s Town, POST Houston, and CAMH.

One Sample Cultural Foundation
The organization will use its grant to produce the Ethnography of Afro-Venezuelan Music, a multidisciplinary educational conference that includes videos, music, and dance that exploring the syncretism of African culture and European religious practices in Venezuela through music. This free event will take place twice — at the Institute of Hispanic Culture of Houston on October 10 and at Teatro Bilingüe de Houston on April 13, 2025. The project aims to strengthen ties between the African American and Venezuelan communities and promote a dynamic cultural exchange.

SoulSista Art Foundation
The organization hosts a conference highlighting Houston’s contributions to the new music business at Houston Warehouse Studio on November 11. Free and open to the general public, it will include performances from selected poets and Afrobeats artists who have been recognized over the years in Houston, along with a DJ and food trucks. Donations will be accepted.

Art + Neighborhood Cultural Destinations

DaCamera
The music organization will use its grant for a series of jazz concerts at the historic El Dorado Ballroom in Third Ward. DaCamera at The Eldorado: Rising Jazz Stars features up-and-coming jazz artists from around the country, providing a new opportunity for Houstonians to experience the next generation of outstanding jazz talent. Concerts begin in October and run through May 2025. All performances will be pay-what-you-can.

Dance Afrikana
A curated exhibition, digital dance archive, and a book are planned as part of the organization's Black Dance in Texas multidisciplinary project. Documenting the rich history of Black dance in the state, this project is an extension of the research project by Dance Afrikana’s founder and Scholar-in-Residence for Rice University’s CERCL Program at the African American History Research Center Gregory Campus.

Norma Jo Thomas
The composer's original musical, Carol of the Bells, will have its world premiere on December 14 at the C. Lee Turner Performing Arts Center on the campus of Lone Star College. The holiday offering is part of Thomas' ongoing tradition to bring cultural programming to the community, and is part of an Acres Homes community collaboration.

The Pilot Dance Project

Celebrated Houston-based choreographer Cynthia Garcia presents Loteria, which brings to life the characters of the traditional Mexican board game. In an urban landscape of constant gentrification, often cultural signifiers, customs, and traditions are left behind to show the legacies of cultural communities. The work will be performed at two major cultural events in gentrified neighborhoods that have histories as Mexican and Mexican American neighborhoods, MECA’s Day of the Dead Festival in October and the MD Anderson YMCA’s annual posada in Near Northside in December.

University of Houston Foundation
Seven-time Grammy Award-winner Terence Blanchard will engage communities from Third Ward and downtown Houston in a series of events. In addition to performing a concert, the jazz legend will collaborate with University of Houston and University of Houston-Downtown students. Performance will take place November 7, 8, and 10 at the Wortham Theater Center or at the University of Houston Moores School of Music. A fireside chat and workshop are also part of the visit.

Art + Resilience Awareness

Group Acorde
The organization's Batimento Cardiaco is a new work that depicts Houstonians' mental health before, during, and after a natural disaster occurs. It will premiere at the MATCH October 3 and 4, and feature musicians, two contemporary dance choreographers, and a visual artist who've collaborated on this important work. Sets and costumes are made of recyclable materials. A discussion will follow the performance. Rehearsals streamed on Group Acorde's social media will give audiences a look at the work as it develops.

Lance Flowers
The artists solo exhibit, Take Me As I Am, takes place simultaneously at the Hogan Brown Gallery in Third Ward and Yale University’s Institute for Sacred Music. It's a collection of new 2D works, videography, music, and photography pieces highlighting Third Ward and its community, and all the materials used will be gathered from the Third Ward. It's curated by gallery director Robert Hodge. The Yale portion of this show has received its own funding.

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This article originally ran on CultureMap.

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