Houston hospital doles out DEI funds, investors join prestigious programs, and more local innovation news

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A new report finds that the Lone Star State isn't prime for innovation jobs — and more Houston innovation news. Photo via Getty Images

Houston's summer has been heating up in terms of innovation news, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, Houston investors were tapped for impressive roles, a local hospital system has invested in the city's diversity and inclusion, and more.

Houston Methodist awards more than $4.6 million for 2022 DEI Grant program

Ryane Jackson, vice-president, community benefits at Houston Methodist, oversees the grant program. Photo courtesy of Houston Methodist

Houston Methodist announced grants to 59 Houston-area nonprofit organizations totalling more than $4.6 million thanks to the Houston Methodist Diversity, Equity & Inclusion Grant Program. The program supports "community initiatives focused on addressing the social determinants of health that lead to health inequities within racial, ethnic and social minorities, including women, people experiencing homelessness, older adults, the LGBTQ+ community, immigrants and more," per a news release.

It's the second year for the DEI Grant Program, and the latest donations will support more than 100,000 people in the Houston area through 29 healthy neighborhood programs, 16 economic empowerment programs, and 17 educational empowerment programs.

“It’s incredibly encouraging to see so many local non-profit organizations working to close the health and social disparity gaps that exist among minority groups in the Houston area,” says Ryane Jackson, vice-president, community benefits at Houston Methodist, in the release. “The goal of the Houston Methodist DEI grant program is to enact meaningful change. For us, that change entails working together with local charity agencies in our collective pursuit to build a healthier Houston that reaffirms the value and worth of everyone. Entering our second year of funding, we’re pleased to support even more local organizations this year who are critical in shaping our community.”

The program has two types of grant funding — the Social Equity Grant for health equity programs targeting racial and ethnic minorities, and the DEI Grant, which provides resources for operating growing agencies serving broader minority communities.

Some examples of the grants are:

  • DEI Grant to the The Montrose Center, which empowers the LGBTQ+ community and their families to live healthier, more fulfilling lives. DEI grant funds will benefit LGBTQ+ seniors and African American seniors from Third Ward in need of affordable and affirmative housing and will enable the hiring of a case manager to support the initiative.
  • DEI Grant tp the Santa Maria Hostel, which offers a comprehensive continuum of care for women and their families including residential detoxification, substance use disorder treatment for women, and emergency and transitional housing. DEI Grant funding will support the Recovery Support Services Program that assists formerly incarcerated women with housing and economic stability through salary support for Peer Recovery Coaches. This agency is the only recovery agency that allows women to keep their children with them while going through the program.
  • Social Equity Grant to Boat People SOS - Houston, a nonprofit social and legal services provider whose purpose is to empower, organize, and equip immigrant communities in their pursuit of liberty and dignity. The Houston Methodist Social Equity grant funding will support their senior services program designed to address social support needs and provide resources to Vietnamese seniors.

2 Mercury investors named to prestigious programs

Samantha Lewis and Aziz Gilani of Mercury have each received exciting appointments. Photos via Mercury

Houston-based venture capital firm has two employees to celebrate. Samantha Lewis, principal at Mercury, was announced as a member of the Class 27 of the Kauffman Fellows Program, a group of global innovation investors, just after Aziz Gilani, managing director at the firm, was appointed to the National Advisory Council on Innovation and Entrepreneurship, a Federal advisory committee that advises the United States Secretary of Commerce.

For Lewis, the appointment enrolls her in the two-year program, which is described as "a United Nations of venture investing," in a news release. She joins a network of 765 fellows — including 59 in the current cohort — spanning six continents and representing over 670 VC firms around the globe.

At NACIE, Gilani was one of 32 leaders appointed by U.S. Secretary of Commerce Gina M. Raimondo last month. The group, according to a news release, will be tasked with "developing a National Entrepreneurship Strategy that strengthens America’s ability to compete and win as the world’s leading startup nation and as the world’s leading innovator in critical emerging technologies."

Texas ranks as middle of the pack when it comes to innovative states

Texas ranks in the lower half of the nation when it comes to innovation jobs. Chart via Smartest Dollar

The Lone Star State was named the 30th most innovative state, according to a new report from Smartest Dollar. The report evaluated data from 350 metros and all 50 states and sought to identify the locations with the most innovative workers. Researchers calculated a composite innovation index for each location and ranked states accordingly.

Here is a summary of the data for Texas, according to the report:

  • Composite innovation index: 59.30
  • Share of workers in the most innovative jobs: 2.6 percent
  • Total workers in the most innovative jobs: 322,910
  • Average annual wage for all workers: $54,230
  • Average annual wage for workers in the most innovative jobs: $77,098

Here are the statistics for the entire United States:

  • Composite innovation index: 59.53
  • Share of workers in the most innovative jobs: 3.1 percent
  • Total workers in the most innovative jobs: 4,428,790
  • Average annual wage for all workers: $58,260
  • Average annual wage for workers in the most innovative jobs: $86,562

Applications are open for pitch competition

A new pitch competition is looking for finalists. Photo via Getty Images

Applications are now open for the Black Girl Ventures x Omaze Houston pitch competition. The deadline to submit is July 1.

This fall, seven finalists will pitch their businesses to a panel of judges, and the first place winner will win $10,000. Second and third place winners will receive $6,000 and $2,000, respectively. Capital One will match funds, effectively doubling the prize money for the top three finalists.

Eligibility includes Black and Brown woman-identifying founders with revenue-generating (under $1 million) businesses. Founders can submit their applications online. Finalists will be notified on July 18.

Black Girl Ventures has been active in Houston since 2020. According to the organization, the region has six Change Agents, or fellows, who work to strengthen and expand the local entrepreneurial ecosystem.

Houston startup joins national 5G accelerator cohort

Houston startup joins a cohort of companies changing the future of 5G. Photo via Getty Images

A Houston company has been named to a new 5G-focused accelerator program. The gBETA 5G Technology Spring 2022 cohort includes Houston-based Ohana. Using advertising revenue, the company brings free access to information and connectivity to the world and is planning to roll out a 5G smartphone and data plan free to users across the globe later this year.

gBETA, which has an industry agnostic cohort ongoing in Houston, also has this 5G-focuset version that follows a similar structure. The five companies will go through the free, seven-week accelerator — that kicked off May 5 — and receive intensive and individualized coaching and access to gener8tor’s national network of mentors, customers, corporate partners, and investors.

The program will culminate with the gener8tor Showcase Day in the fall, which will highlight each of the five companies.

“We’re so fortunate to have such a diverse set of founders from across the country, with expertise across the internet technology and communications continuum,” says Doug Applegate, gBETA director for the 5G Technology program. “They highlight the capabilities and possibilities of what 5G Technology can bring to the world, and we’re excited to see how the companies grow.”

The other companies include Chicago-based Socian Technologies, Fishers, Indiana-based Qumulex Boston-based Mentore, and Dallas-based Taubyte.

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Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

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With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

5+ must-know application deadlines for Houston innovators

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Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

2026 Energy Venture Day & Pitch Competition

Deadline: Feb. 13

Details: The Rice Alliance, the Houston Energy Transition Initiative (HETI) and TEX-E will present the annual Energy Venture Day and Pitch Competition during CERAWeek on March 24-25, 2026. Energy Venture Day features two days of presentations by energy tech ventures driving efficiency and advancements toward the energy transition. On March 24, the Pitch Preview at the Ion will feature over 50 companies presenting in front of Rice Alliance's robust network of investors and industry partners. On March 25, the Energy Venture Day and Pitch Competition during CERAWeek will showcase 36 ventures at the George R Brown Convention Center. The pitch competition is divided up into the TEX-E university track, in which Texas student-led energy startups compete for $50,000 in cash prizes, and the industry ventures track. The industry track is subdivided into three additional tracks, spanning materials to clean energy. The top three companies from each industry track will be named. The winner of the CERAWeek competition will also have the chance to advance and compete for the $1 million investment prize at the Startup World Cup. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.

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