3 female Houston innovators to know this week

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This week's roundup of Houston innovators includes Nicole Rogers of Validere, Allie Danziger of Ampersand, and Ashley Small of Medley Inc. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three female innovators across industries — from energy tech to business entrepreneurship.

Nicole Rogers, senior vice president at Validere

Nicole Rogers, senior vice president at Validere, joins the Houston Innovators Podcast to discuss how her company has grown exponentially over the past year. Photo courtesy of Validere

Nicole Rogers joined Canadian startup Validere during the summer last year — right smack dab in the middle of a pandemic. But despite COVID-19 and the drop in oil prices, the energy company grew exponentially — in clientbase, in venture capital support, and in employee count.

"One of the things we found that was to our advantage throughout the pandemic was a lot of folks in oil were having a career identity crisis. Oil really struggles with employment elasticity," Rogers says. "A lot of the colleagues we were talking to were just fatigued with the ups and downs going on in the past decade."

Rogers, who's based in the company's Houston office, shares more about Validere's growth and opportunities in the new year — plus what she thinks Houston needs to do to maintain its status of energy capital of the world in the episode. Click here to read more and to stream the podcast.

Allie Danziger, founder of Ampersand

Houston entrepreneur, Allie Danziger, wanted to create a program for young professionals looking to gain experience in unprecedented times. Photo courtesy of Ampersand

Allie Danziger has two small children, but she started thinking about if her kids were college age, would she want them to enroll in a virtual college experience or hold off for a time where they could have a more traditional experience. Realizing she probably wasn't alone, she thought about how she could create an alternative for high school grads — in this time of the pandemic but also in a time where college degrees aren't the best option for job security.

"I really believe that it scales way beyond this pandemic," says Danziger. In her research, she saw a lack of career-focused gap curriculums and resources available. "There are no programs that help you determine what the right path for you is—to really do that self-exploration and then apply it to your career path," she explains. Click here to read more.

Ashley Small, founder and CEO of Medley Inc.

From events to online shopping — here are four tech trends to look out for this year according to Ashley Small. Photo courtesy of Medley

It's a new year and the perfect time to reflect on where society is at from a technological standpoint. In light of the pandemic and an overarching trend of tapping into tech to provide solutions to COVID-19-related challenges, 2021 will likely see more of these trends.

"As a business owner, it's clear to me that many of these shifts will persist long after the pandemic has ended," writes Ashley Small, founder and CEO of Medley Inc., in a guest column for InnovationMap.

From subscriptions to online shopping, Small highlighted the types of tech in the digital realm that deserve our special attention in 2021. Click here to read more.

Nicole Rogers, senior vice president at Validere, joins the Houston Innovators Podcast to discuss how her company has grown exponentially over the past year. Photo courtesy of Validere

Canadian energy tech startup doubles down on Houston and plans to scale

HOUSTON INNOVATORS PODCAST EPISODE 65

While the pandemic and last year's drop in oil prices may have caused their own set of challenges, at least one energy tech startup saw plenty of opportunity for growth amid the unprecedented times.

In 2020, Validere, which is based in Calgary and has a growing office in Houston, closed a $15 million series A round with participation from two Silicon Valley firms — Greylock and Wing Venture Capital — as well as doubled their employee base. The company has software and hardware supplychain solutions for oil and gas companies that improves visibility and trust in oil testing.

"We came out of our Q2 and Q3 having the best quarters that the company had ever had," says Nicole Rogers, senior vice president at Validere, on this week's episode of the Houston Innovators Podcast. "Many of our results were tied to our customers being forced to do something differently. When you can't earn your profits the same way you did before, you will constantly look for profits somewhere else — and we are core to that movement."

Hiring for startups is always a challenge — especially competing with both big tech and big oil companies — but Rogers says this is another example of how both the instability in oil and gas coupled with COVID-19-caused crisis played to their benefit.

"One of the things we found that was to our advantage throughout the pandemic was a lot of folks in oil were having a career identity crisis. Oil really struggles with employment elasticity," Rogers says. "A lot of the colleagues we were talking to were just fatigued with the ups and downs going on in the past decade."

Validere's technology is also beneficial to oil and gas companies who are looking to use data and supply chain optimization increase transparency in a market that is prioritizing sustainability and ESG — Environmental, Social, and Corporate Governance.

"ESG is a supply chain problem and opportunity — and that's what we do at Validere," Rogers says. "We're transforming the world's largest supply chains through the use of software, machine learning, artificial intelligence, and our staff."

Rogers, who's based in the company's Houston office, shares more about Validere's growth and opportunities in the new year — plus what she thinks Houston needs to do to maintain its status of energy capital of the world in the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Austin company to bring AI-powered school to The Woodlands

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Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston space tech co. lands $175M and more innovation news to know

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Editor's note: The top Houston innovation news for the month includes major fundraising rounds for two Houston scaleups and local inductees into the National Academy of Inventors. Here are the five most-read InnovationMap headlines from March 1-15, 2026:

1. Intuitive Machines secures $175M equity investment to fuel growth

Intuitive Machines has landed a $175 million investment as it looks secure satellite deals and develop space-based data centers. Photo courtesy Intuitive Machines.

Houston-based space infrastructure and services company Intuitive Machines has secured a $175 million equity investment from unidentified institutional investors. The investors received shares of Class A stock in exchange for their funding. Publicly held Intuitive Machines (Nasdaq: LUNR) says it plans to use the capital to help build revenue and invest in technology, including communications and data-processing networks. Continue reading.

2. Houston e-commerce giant Cart.com raises $180M, surpasses $1B in funding

Cart.com has raised $180 million to scale its logistics network, expand AI capabilities and develop workflow automation tools. Photo courtesy of Cart.com

Houston-based commerce and logistics platform Cart.com has raised $180 million in growth capital from private equity firm Springcoast Partners, pushing the startup past the $1 billion funding mark since its founding in 2020. Cart.com says it will use the capital to scale its logistics network, expand AI capabilities and develop workflow automation tools. Continue reading.

3. Houston leads Texas with 7 new National Academy of Inventors senior members

The University of Houston has more faculty named to this year’s senior member class of the National Academy of Inventors than any other Texas institution. Photos courtesy UH.

The University of Houston is now home to seven new senior members of the National Academy of Inventors. According to UH, its seven new members represent the largest group from any single Texas institution this year, bringing the university's total senior member count to 46. Continue reading.

4. Booming Houston suburb launches innovation grant to attract startups

The City of Sugar Land is putting money on the table to support startups that relocate jobs to southwest Houston. Photo via Getty Images.

Think you’ve got a burgeoning startup? Consider moving it to southwest Houston. The City of Sugar Land announced the Sugar Land Starts Innovation Fund to support companies that move jobs to the area. Continue reading.

5. 6+ can't-miss Houston business and innovation events in March

From CERAWeek to H-Town Roundup, here's what not to miss this month and how to register. Photo courtesy of CERAWeek

March brings the return of some of Houston’s signature innovation events, plus insightful talks and celebrations in honor of Women's History Month. Here’s what not to miss and how to register. Continue reading.

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

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