3 female Houston innovators to know this week

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This week's roundup of Houston innovators includes Nicole Rogers of Validere, Allie Danziger of Ampersand, and Ashley Small of Medley Inc. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three female innovators across industries — from energy tech to business entrepreneurship.

Nicole Rogers, senior vice president at Validere

Nicole Rogers, senior vice president at Validere, joins the Houston Innovators Podcast to discuss how her company has grown exponentially over the past year. Photo courtesy of Validere

Nicole Rogers joined Canadian startup Validere during the summer last year — right smack dab in the middle of a pandemic. But despite COVID-19 and the drop in oil prices, the energy company grew exponentially — in clientbase, in venture capital support, and in employee count.

"One of the things we found that was to our advantage throughout the pandemic was a lot of folks in oil were having a career identity crisis. Oil really struggles with employment elasticity," Rogers says. "A lot of the colleagues we were talking to were just fatigued with the ups and downs going on in the past decade."

Rogers, who's based in the company's Houston office, shares more about Validere's growth and opportunities in the new year — plus what she thinks Houston needs to do to maintain its status of energy capital of the world in the episode. Click here to read more and to stream the podcast.

Allie Danziger, founder of Ampersand

Houston entrepreneur, Allie Danziger, wanted to create a program for young professionals looking to gain experience in unprecedented times. Photo courtesy of Ampersand

Allie Danziger has two small children, but she started thinking about if her kids were college age, would she want them to enroll in a virtual college experience or hold off for a time where they could have a more traditional experience. Realizing she probably wasn't alone, she thought about how she could create an alternative for high school grads — in this time of the pandemic but also in a time where college degrees aren't the best option for job security.

"I really believe that it scales way beyond this pandemic," says Danziger. In her research, she saw a lack of career-focused gap curriculums and resources available. "There are no programs that help you determine what the right path for you is—to really do that self-exploration and then apply it to your career path," she explains. Click here to read more.

Ashley Small, founder and CEO of Medley Inc.

From events to online shopping — here are four tech trends to look out for this year according to Ashley Small. Photo courtesy of Medley

It's a new year and the perfect time to reflect on where society is at from a technological standpoint. In light of the pandemic and an overarching trend of tapping into tech to provide solutions to COVID-19-related challenges, 2021 will likely see more of these trends.

"As a business owner, it's clear to me that many of these shifts will persist long after the pandemic has ended," writes Ashley Small, founder and CEO of Medley Inc., in a guest column for InnovationMap.

From subscriptions to online shopping, Small highlighted the types of tech in the digital realm that deserve our special attention in 2021. Click here to read more.

Nicole Rogers, senior vice president at Validere, joins the Houston Innovators Podcast to discuss how her company has grown exponentially over the past year. Photo courtesy of Validere

Canadian energy tech startup doubles down on Houston and plans to scale

HOUSTON INNOVATORS PODCAST EPISODE 65

While the pandemic and last year's drop in oil prices may have caused their own set of challenges, at least one energy tech startup saw plenty of opportunity for growth amid the unprecedented times.

In 2020, Validere, which is based in Calgary and has a growing office in Houston, closed a $15 million series A round with participation from two Silicon Valley firms — Greylock and Wing Venture Capital — as well as doubled their employee base. The company has software and hardware supplychain solutions for oil and gas companies that improves visibility and trust in oil testing.

"We came out of our Q2 and Q3 having the best quarters that the company had ever had," says Nicole Rogers, senior vice president at Validere, on this week's episode of the Houston Innovators Podcast. "Many of our results were tied to our customers being forced to do something differently. When you can't earn your profits the same way you did before, you will constantly look for profits somewhere else — and we are core to that movement."

Hiring for startups is always a challenge — especially competing with both big tech and big oil companies — but Rogers says this is another example of how both the instability in oil and gas coupled with COVID-19-caused crisis played to their benefit.

"One of the things we found that was to our advantage throughout the pandemic was a lot of folks in oil were having a career identity crisis. Oil really struggles with employment elasticity," Rogers says. "A lot of the colleagues we were talking to were just fatigued with the ups and downs going on in the past decade."

Validere's technology is also beneficial to oil and gas companies who are looking to use data and supply chain optimization increase transparency in a market that is prioritizing sustainability and ESG — Environmental, Social, and Corporate Governance.

"ESG is a supply chain problem and opportunity — and that's what we do at Validere," Rogers says. "We're transforming the world's largest supply chains through the use of software, machine learning, artificial intelligence, and our staff."

Rogers, who's based in the company's Houston office, shares more about Validere's growth and opportunities in the new year — plus what she thinks Houston needs to do to maintain its status of energy capital of the world in the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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CPRIT hires MD Anderson official as chief cancer prevention officer

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The Austin-based Cancer Prevention and Research Institute of Texas, which provides funding for cancer research across the state, has hired Ruth Rechis as its chief prevention officer. She comes to CPRIT from Houston’s University of Texas MD Anderson Cancer Center, where she led the Cancer Prevention and Control Platform.

Before joining MD Anderson, Rechis was a member of the executive leadership team at the Livestrong Foundation, an Austin-based nonprofit that supports people affected by cancer.

“Ruth has widespread connections throughout the cancer prevention community, both in Texas and across the nation,” CPRIT CEO Kristen Doyle said in a news release. “She is a long-term passionate supporter of CPRIT, and she is very familiar with our process, programs, and commitment to transparency. Ruth is a terrific addition to the team here at CPRIT.”

Rechis said that by collaborating with researchers, policymakers, public health leaders and community partners, CPRIT “can continue to drive forward proven prevention strategies that improve health outcomes, lower long-term costs, and create healthier futures for all.”

At MD Anderson, Rechis and her team worked with more than 100 organizations in Texas to bolster cancer prevention initiatives at clinics and community-based organizations.

Rechis is a longtime survivor of Hodgkin lymphoma, a type of cancer that affects the lymph nodes, which are part of a person’s immune system.

6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston Community College, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Former NASA astronaut, official joins Venus Aerospace board

astronaut appointment

Retired Air Force colonel and former NASA astronaut Pamela Melroy, who previously served as deputy administrator of NASA, recently joined the board of directors at Houston-based Venus Aerospace.

Venus Aerospace, a startup founded in 2020, develops rocket engine technology, including rotating rocket detonation engines for hypersonic flights. These engines promise higher power, greater fuel efficiency and lower emissions than conventional rocket engines or jet engines, according to the Interesting Engineering website. The global rocket propulsion market is expected to grow from $9.5 billion in 2025 to $29.9 billion by 2034, according to a forecast by ResearchAndMarkets.com.

“Advanced rocket propulsion has been of interest to me for over a decade, and Venus Aerospace’s recent achievements in demonstrating the stability of rotating detonation rocket engines represent a significant development,” says Melroy, who left NASA earlier this year and is now a self-employed consultant living in Arlington, Virginia.

Melroy, a member of the United States Astronaut Hall of Fame, has built an illustrious career in the aerospace sector. Aside from being a NASA official, she was:

  • One of only two female astronauts to command a space shuttle mission
  • Deputy program manager of Orion space exploration initiatives at aerospace and defense contractor Lockheed Martin
  • Senior technical adviser and director of field operations for the Federal Aviation Administration’s Office of Commercial Space Transportation, where she came up with the first safety guidelines for commercial human spaceflight
  • Deputy director of the Tactical Technology Office at the Defense Advanced Research Projects Agency (DARPA).
  • An adviser for the establishment of the Australian Space Agency

Venus Aerospace said in a news release that as a leader at three federal agencies, “Melroy shaped America’s strategy in space, accelerated commercial space partnerships, and deepened space exploration.”

Sassie Duggleby, co-founder and CEO of Venus Aerospace, called Melroy “a preeminent leader in the world of aerospace.”

In May, Venus Aerospace completed the inaugural test flight of its rotating detonation rocket engine. The startup, whose headquarters is at the Houston Spaceport, says it’s the only company in the world that has manufactured a flight-proven, high-thrust rotating detonation rocket engine.

On the horizon for Venus Aerospace is production of Stargazer M4, a high-speed aircraft capable of two-hour global travel.

Venus Aerospace’s investors include Airbus Ventures, America’s Frontier Fund, Trousdale Ventures, and Prime Movers Lab. The startup also gets support from the Air Force Research Laboratory (AFWERX), the Air Force, NASA and DARPA.

Jordan Blashek, co-founder and managing partner of America’s Frontier Fund, which backs startups creating breakthrough technologies, said his firm’s investment in Venus Aerospace “underscores our focus on supporting American companies that are revolutionizing industries of the future.”

“With recent hypersonic advancements from China and Russia, safeguarding American innovation and securing our industrial base has never been more urgent,” Blashek added. “Venus Aerospace is poised to redefine hypersonic flight and ensure America’s continued leadership in aerospace innovation.”

Since its founding, Venus Aerospace has raised $78.3 million in investments, according to PitchBook data.

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