These three Houstonians have a lot up their sleeves for their companies. Courtesy photos

This week's three Houston entrepreneurs are all about improving access for startups — either to capital or to resources — and that's no small undertaking in a market like Houston. With its urban sprawl and large population, Houston's been considered to have a connectivity problem. Luckily, these three folks have solutions.

Grace Rodriguez, executive director and co-founder of Impact Hub Houston

Grace Rodriguez is the co-founder and executive director of Impact Hub Houston. Courtesy of Grace Rodriguez

Grace Rodriguez has been working to launch Impact Hub Houston for a while now, but her and her team's moment has come. For Rodriguez, the goal is to both advance Houston startups, as well as the innovation ecosystem as a whole.

"Our real vision is to help Houston become a role model for how the world solves the most pressing issues," she says. "We want to show the rest of the world that Houston has the talent, expertise, insight, and resources to solve issues around the world." Read more about Rodriguez and Impact Hub Houston here.

Nicolas Carnrite, co-founder of LetsLaunch

Nicolas Carnrite founded LetsLaunch to improve access to funding. Courtesy of LetsLaunch

Something didn't add up for Nicolas Carnrite. The opportunity to invest in companies was limited to such a small percentage of the population.

"There's something like 30 million people globally that have a $1 million net worth, which is the definition of being an accredited investor," Carnrite says. "Thirty million people out of 7.7 billion, so it's a little less than half a percentage."

This translated into an opportunity to create LetsLaunch, a securities investment online platform that democratizes investment. The Houston company has taken it a step further in its recent partnership with The Cannon. Read more about this partnership here.

Youngro Lee, co-founder and CEO of NextSeed

Youngro Lee NextSeed

Youngro Lee, co-founder and CEO of NextSeed, wants to create a connection between business and their communities. Courtesy of NextSeed

Thanks to a recent SEC accreditation, Youngro Lee is now able to announce that his Houston online fundraising platform, NextSeed, is a broker-dealer. The platform, which has helped the likes of Buffalo Bayou Brewery and The Waffle Bus raise thousands of capital dollars, is now able to offer its community more investment opportunities. Read more about what the deal means for the company here.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”

Chevron enters the lithium market with major Texas land acquisition

to market

Chevron U.S.A., a subsidiary of Houston-based energy company Chevron, has taken its first big step toward establishing a commercial-scale lithium business.

Chevron acquired leaseholds totaling about 125,000 acres in Northeast Texas and southwest Arkansas from TerraVolta Resources and East Texas Natural Resources. The acreage contains a high amount of lithium, which Chevron plans to extract from brines produced from the subsurface.

Lithium-ion batteries are used in an array of technologies, such as smartwatches, e-bikes, pacemakers, and batteries for electric vehicles, according to Chevron. The International Energy Agency estimates lithium demand could grow more than 400 percent by 2040.

“This acquisition represents a strategic investment to support energy manufacturing and expand U.S.-based critical mineral supplies,” Jeff Gustavson, president of Chevron New Energies, said in a news release. “Establishing domestic and resilient lithium supply chains is essential not only to maintaining U.S. energy leadership but also to meeting the growing demand from customers.”

Rania Yacoub, corporate business development manager at Chevron New Energies, said that amid heightening demand, lithium is “one of the world’s most sought-after natural resources.”

“Chevron is looking to help meet that demand and drive U.S. energy competitiveness by sourcing lithium domestically,” Yacoub said.

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This article originally appeared on EnergyCapital.