The Digital Fight Club made its Houston debut on November 20 at White Oak Music Hall. Emily Jaschke/InnovationMap

What do you get when you cross the information of an innovation panel with the ferocity of a boxing match? A verbal sprawling among innovation leaders that can only be known as the Digital Fight Club.

Houston's DFC came about with the help of Accenture, which had been a partner at the Dallas events, and InnovationMap, who teamed up as presenting sponsors for the event. DFC's founder, Michael Pratt, came up with the idea for Digital Fight Club as a way to liven up technology-focused events and networking opportunities.

The setup of the event is five fights, 10 fighters, and five judges. Each fighter has just a couple minutes to take their stand before the event moves on.

"This is Digital Fight Club," says Pratt, CEO of the company. "You get subject matter experts, and serious founders and CEOs on the stage and make them make their case. You learn something, it's a lot of fun, and it's a lot better than a panel."

The hour of fighting is coupled with a VIP event ahead of the showdown and an after party where further networking can continue on. At Houston's VIP event, InnovationMap got to check in with partners, fighters, and referees about how they thought the event was going to pan out. Check out the VIP event video here.

The panel of referees included Gabriella Rowe, CEO of Station Houston; Denise Hamilton, CEO of Watch Her Work; TimKopra, partner at Blue Bear Capital; Lance Black, Director at TMCx; and Barbara Burger, president of Chevron Technology Ventures.

The refs asked two questions per fight, and were able to vote on the winners of each round — as was the audience through an interactive web-based application. The break down of the fights, topics, and winners are as follows:

Fight #1: Future Workforce of Robotics/AI. Matt Hager, CEO of Poetic Systems, vs Pablo Marin, senior AI Leader, Microsoft. Hager took the win with 77 percent of the vote.
Fight #2: Whose responsibility is cybersecurity. Ted Gutierrez, CEO of SecurityGate vs Tara Khanna, managing director and Security Lead at Accenture. Khanna won this round, snagging 66 percent of the votes.
Fight #3: Oil & Gas Industry and the Environment. Michael Szafron - commercial adviser for Cemvita Factory, vs Steven Taylor, co-founder of AR for Everyone. Szafron received 76 percent of the voites, securing the win.
Fight #4: Digital in our personal lives. Grace Rodriguez, CEO of ImpactHub, vs Javier Fadul, chief innovation officer at HTX Labs. Rodriguez won with the largest margin of the night — 85 percent.
Fight #5: Future of Primary Care Geetinder Goyal, CEO of First Primary Care, vs Nick Desai, chief medical information officer at Houston Methodist. Goyal received 72 percent of the votes to take home the win.

The fights were heated, and some of the fighters had knockout quotes, from Hager's "AI is mostly bullshit" to Khanna's "Compliance doesn't mean you're secure." For more of the knockout quotes, click here.

The fight is on

Emily Jaschke/InnovationMap

Mike Pratt, who hosted the event, founded the Digital Fight Club in 2016.

Ten Houston innovators took the stage for five fights on the role technology plays in the future of industry. Emily Jaschke/InnovationMap

Overheard: Local fighters land knockout statements at Houston's first Digital Fight Club

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On Wednesday, Houston's innovation ecosystem hosted the rowdiest crowd at a professional business event that the city has ever seen.

Digital Fight Club, a Dallas-based event company, had its first Houston event at White Oak Music Hall on November 20 thanks to presenting sponsors Accenture and InnovationMap. The event featured 10 fighters and five referees across five fights that discussed cybersecurity, the future of primary care, and more.

"This is Digital Fight Club," says Michael Pratt, CEO of the company. "You get subject matter experts, and serious founders and CEOs on the stage and make them make their case. You learn something, it's a lot of fun, and it's a lot better than a panel."

If you missed the showdown, here are some of the nights zingers made by the entrepreneurs and subject matter experts that were the fighters of the evening.

"I believe that computers can get a lot of information to create [something new]. That's my job, that's what I do, and I see it done."

Pablo Marin, senior AI leader at Microsoft, during the fight on robotics and AI in the workforce. Marin's argument was that artificial intelligence and robotics can and will replace all repetitive jobs. However, he also believes that computers have the ability to create, as well, based on their ability to see the whole world and have access to all the world's information.

"AI is mostly bullshit."

Matthew Hager, CEO of Poetic Systems. Hager, who won the first fight of the night, responded to Marin that, while businesses like to believe that AI is actually able to deliver results so that they can sell more, the technology hasn't actually arrived yet. Plus, Hager says AI will never be creative without the human element. "Creativity is about who created it. It's about the photographer, not the camera," he says.

"What if the seatbelt laws and the speed limits were defined by Dodge, Ford, or Chrysler?"

Ted Gutierrez, CEO and co-founder of Security Gate, who argued for government to take the reigns of cybersecurity. He adds that companies are never going to be able to agree to one set of rules. "We gotta get one group to set the standard, and it's up to everyone else to refine that and innovate for it," he says.

"Compliance doesn't mean you're secure."

Tara Khanna, managing director and security lead at Accenture, who won the fight on cybersecurity needing to be figured out by the business industry. She argues that the private sector wins the war on talent and recruiting, so it has the money and resources to dedicate to the issue in more ways than the government ever will.

"I was born, I'm going to die, and there is nothing like earth in the universe as we know it. It is worth preserving and protecting."

Steven Taylor, co-founder of AR for Everyone, in the fight over the oil and gas industry's responsibility to the environment. He argued that it's going to be a mix of policy and corporate initiatives that changes the industry.

"I think the free market is going to get there if the consumer has the choice to pick what they want to do."

Michael Szafron, commercial adviser for Cemvita Factory, who took home the win for the oil and gas and the environment fight. Szafron's argument was that corporations are going to do what their consumers want, so that's who would drive them to action. "Let's look at California —very regulated environmentalists, and a million of those people get moved to Texas," he says.

"Disconnecting our personal lives from technology would not only limit ourselves, but it would also limit our capacity to adopt those tools to the needs of our society." 

Javier Fadul, chief innovation officer at HTX Labs, during the fight on digital in our personal lives. Fadul argues that not only does technology allow us to connect worldwide, but disconnecting would prevent that technology from developing further.

"I love tech, but now that it's on all the time everywhere, we need to make time to unplug."

Grace Rodriguez, CEO of Impact Hub Houston, who won the fight on personal technology. She says that yes, technology can help international connectivity, but it does more harm than good as people use personal tech as a default or distraction from humans right in front of them. "When your with people, be present," she says.

"Part of our innovation to redesign primary care is really to deploy technology out there to seamlessly provide care."

Nick Desai, chief medical information officer at Houston Methodist, who argued that the future of primary care is new innovations within traditional medicine. He adds that virtual care, which is something Methodist is working on, can help improve accessibility.

"The future of primary care is here. It's called direct primary care." 

Geetinder Goyal, CEO of First Primary Care, who won the fight on the future of primary care with his argument for a new, free market approach to medicine. Direct primary care opens up treatment and access to physicians with a monthly fee for patients to work outside of health care plans.

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Rice research breakthrough paves the way for advanced disease therapies

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Bioengineers at Rice University have developed a “new construction kit” for building custom sense-and-respond circuits in human cells, representing a major breakthrough in the field of synthetic biology, which could "revolutionize" autoimmune disease and cancer therapeutics.

In a study published in the journal Science, the team focused on phosphorylation, a cellular process in the body in which a phosphate group is added to a protein, signaling a response. In multicellular organisms, phosphorylation-based signaling can involve a multistage, or a cascading-like effect. Rice’s team set out to show that each cycle in a cascade can be treated as an elementary unit, meaning that they can be reassembled in new configurations to form entirely novel pathways linking cellular inputs and outputs.

Previous research on using phosphorylation-based signaling for therapeutic purposes has focused on re-engineering pathways.

“This opens up the signaling circuit design space dramatically,” Caleb Bashor, assistant professor of bioengineering and biosciences and corresponding author on the study, said in a news release. “It turns out, phosphorylation cycles are not just interconnected but interconnectable … Our design strategy enabled us to engineer synthetic phosphorylation circuits that are not only highly tunable but that can also function in parallel with cells’ own processes without impacting their viability or growth rate.”

Bashor is the deputy director for the Rice Synthetic Biology Institute, which launched last year.

The Rice lab's sense-and-respond cellular circuit design is also innovative because phosphorylation occurs rapidly. Thus, the new circuits could potentially be programmed to respond to physiological events in minutes, compared to other methods, which take hours to activate.

Rice’s team successfully tested the circuits for sensitivity and their ability to respond to external signals, such as inflammatory issues. The researchers then used the framework to engineer a cellular circuit that can detect certain factors, control autoimmune flare-ups and reduce immunotherapy-associated toxicity.

“This work brings us a whole lot closer to being able to build ‘smart cells’ that can detect signs of disease and immediately release customizable treatments in response,” Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice who is the lead author on the study, said in a news release.

Ajo-Franklin, a professor of biosciences, bioengineering, chemical and biomolecular engineering and a Cancer Prevention and Research Institute of Texas Scholar, added “the Bashor lab’s work vaults us forward to a new frontier — controlling mammalian cells’ immediate response to change.”

Greentown Labs names new CEO to lead pioneering climate tech incubator

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Houston and Boston climate tech incubator Greentown Labs has named Georgina Campbell Flatter as the organization’s incoming CEO.

Flatter will transition to Greentown from her role as co-founder and executive director of TomorrowNow.org, a global nonprofit that studies and connects next-generation weather and climate technologies with communities most affected by climate change.

“We are at a transformational moment in the energy transition, with an unprecedented opportunity to drive solutions in energy production, sustainability, and climate resilience,” Flatter said in a news release. “Greentown Labs is, and has always been, a home for entrepreneurs and a powerhouse of collaboration and innovation.”

Previously, Flatter worked to launch TomorrowNow out of tomorrow.io, a Boston-based AI-powered weather intelligence and satellite technology company. The organization secured millions in climate philanthropy from partners, including the Gates Foundation, which helped deliver cutting-edge climate solutions to millions of African farmers weekly.

Flatter also spent 10 years at the Massachusetts Institute of Technology (MIT), where she was a senior lecturer and led global initiatives at the intersection of technology and social impact. Her research work includes time at Langer Lab and Sun Catalytix, an MIT – ARPA-E-funded spin-out that focused on energy storage solutions inspired by natural photosynthesis. Flatter is also an Acumen Rockefeller Global Food Systems Fellow and was closely involved with Greentown Labs when it was founded in Boston in 2011, according to the release.

“It’s rare to find an individual who has impressive climate and energy expertise along with nonprofit and entrepreneurial leadership—we’re fortunate Georgie brings all of this and more to Greentown Labs,” Bobby Tudor, Greentown Labs Board Chair and Chairman of the Houston Energy Transition Initiative, said in a news release.

Flatter will collaborate with Kevin Dutt, Greentown’s Interim CEO, and also continue to serve on Greentown’s Board of Directors, which was recently announced in December and contributed to a successful $4 million funding round. She’s also slated to speak at CERAWeek next month.

“In this next chapter, I’m excited to build on our entrepreneurial roots and the strength of our ever-growing communities in Boston and Houston,” Flatter added in a news release. “Together, we will unite entrepreneurs, partners, and resources to tackle frontier challenges and scale breakthrough technologies.”

Greentown also named Naheed Malik its new chief financial officer last month. The announcements come after Greentown’s former CEO and president, Kevin Knobloch, announced that he would step down in July 2024 after less than a year in the role.

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This article originally appeared on our sister site, EnergyCapital.

Houston firm invests $150M in leading 'lab on a chip' medical diagnostics co.

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Houston-based health technology investment firm Hamershlag Private Capital Management Limited (HPCM) announced a $150.15 million venture investment in Patho Care LLC.

Patho Care is a “lab on a chip” medical diagnostics company known for its noninvasive point-of-care testing platforms, such as its Raman spectroscopy-based platform.

Its digital point-of-care testing devices are programmable, mobile, and reusable and can detect current or future respiratory bacterial or viral infections. The company says the technology is more cost-effective and provides results faster than traditional diagnostic methods.

“Patho Care LLC is a distinguished leader in healthcare diagnostics through the utilization of a novel approach with spectroscopy and this investment aligns with HPCM’s strategy of partnering with high-potential companies in dynamic industries,” L. Mychal Jefferson, Chairman of Hamershlag, said in a news release.

The transaction was structured as an acquisition and recapitalization using newly issued common stock and cash, which will work through a newly formed entity, PathoCare Holdings Inc. The deal will also facilitate the repayment of Patho Care LLC's existing financial obligations and settle Patho Care’s outstanding notes, helping ensure the company’s financial readiness, according to the release.

The investment will help Patho Care LLC improve operational efficiencies, broaden its service offerings and continue to innovate in the diagnostic testing space. The companies hope the collaboration will help “unlock new growth opportunities while maintaining the company’s legacy of excellence in an emerging technology,” according to a news release.

“Our commitment to delivering transformative value through innovative investments underscores our confidence in Patho Care’s vision and capabilities,” Jefferson added.