A Houston company has raised additional funding as it grows its encrypted lodging booking platform. Photo via Gustavo Fring/Pexels

A travel booking technology company that's looking to alleviate some of the stresses of finding and making hotel reservations has raised additional seed funding.

Houston-based Pinktada has raised additional funding to the tune of $975,000. Ireland-based Selenean Capital contributed to the seed funding round, joining the company's previous investor True Global Ventures 4 Plus, which has invested $2 million to date. According to Crunchbase data, the latest investment brings the company's total to $3.9 million.

“Selenean Capital’s approach to partnership is identifying real world future needs and then working relentlessly to achieve those goals," says Davin Browne, Selenean’s CEO, in a news release. "Pinktada encapsulates this perfectly with a transformational approach to the hotel booking model built around a brilliant team. We look forward to the partnership and journey with them."

Founded in 2020, Pinktada launched its booking platform earlier this year. The technology — backed by NFT encryption — allows users to sell or trade existing lodging reservations. As many hotels and third-party booking sites offer cheaper non-refundable booking options, Pinktada gives travelers a secure alternative if their plans change. The company's hotel partners can benefit from the transactions, too, per the company's statement.

“We are thrilled with the market validation we are receiving,” says Mark J. Gordon, chief hospitality officer, in the release. “We launched in May with properties in Hawaii and the Dominican Republic, have since added exquisite hotels in Mexico, New York, Miami and San Francisco, and have another 18 in the process of being on-boarded. More important though is the caliber of our partners, which are leading hotel industry names.”

According to the company, membership grew 20 percent in August and 40 percent in September as the platform added new hotel partners.

“We could not be more excited about our prospects," says Lyon Hardgrave, Pinktada’s CEO, in the release. “This investment reflects the significant progress we have made this year. It will allow us to accelerate the onboarding of new hotels, dial up marketing efforts, and continue to evolve our technology to embrace other large opportunities.”

The Founders District in West Houston has an NFT investment opportunity. Rendering via foundersdistrict.com

Developing West Houston district introduces NFT investment opportunity

money moves

Developers are turning to blockchain technology to help finance a new indoor-outdoor bar at Houston’s Founders District innovation campus.

Under the umbrella of the Powder Keg Collective, the Powder Keg bar is selling non-fungible tokens (NFTs) to finance construction and operation of its 14,000-square-foot expansion. NFTs, similar to cryptocurrencies, are stored on a blockchain and represent ownership of a unique asset.

The new venue will be at 1300 Brittmoore Rd., near the existing Powder Keg bar and The Cannon West Houston entrepreneurial hub. Aside from catering to everyday patrons, the venue will host community events, festivals, private events, and concerts.

Buyers of the Powder Keg NFTs will be entitled to gain proceeds from the development, and will receive beer discounts, access to VIP events, and other privileges.

“These utility NFTs provide owners with tangible financial value and membership in a real estate club, not empty hype,” Mark Toon, co-owner of the Powder Keg, The Cannon and the Founders District, says in a news release.

“The Powder Keg Collective is another way we’re building community around technology, demystifying it, and bringing together Houstonians — whether they’re investors, NFT collectors, crypto-enthusiasts, or people who just want a stake in their neighborhood bar.”

On the Ethereum blockchain platform, the collective will sell 2,361 tokens ranging in price from $250 to $500,000 each. Tokens can be purchased with cryptocurrencies or U.S. dollars. The venue itself will accept the same two payment methods.

The Powder Keg is planning an expansion. Photo courtesy

Each NFT pass to Lago Mar Crystal Lagoon is available for $170 to $210. Rendering courtesy of Land Tejas

Hot Houston summer spot plans to sell NFT membership

making waves

One of the most hyped — and most baffling — tech innovations on the planet is making waves in Texas City.

The Lago Mar Crystal Lagoon waterpark says it’s now selling season passes based on NFT technology. NFT stands for non-fungible token.

“At a basic level, an NFT is a digital asset that links ownership to unique physical or digital items, such as works of art, real estate, music, or videos,” the Insider website explains. “NFTs can be considered modern-day collectibles. They’re bought and sold online, and represent a digital proof of ownership of any given item. NFTs are securely recorded on a blockchain — the same technology behind cryptocurrencies — which ensures the asset is one-of-a-kind.”

The Lago Mar lagoon, a 12-acre waterpark that opened in 2020, says its NFT-based season pass may be the first anywhere to enable admission into an attraction. The park’s traditional and NFT season passes provide unlimited access to the lagoon, which hosts annual events like Lagoonfest Texas. The lagoon anchors a planned 100-acre, mixed-use entertainment district.

Uri Man, CEO of The Lagoon Development Co., which developed the Lago Mar venue, says the NFT pass offers perks that a regular pass doesn’t. For example, the NFT pass lets you enjoy special activities at the state’s largest crystal lagoon, such as setting sail with a professional captain or going kayaking.

“This payment option is buzzing around the event and attractions community, with entertainment and crypto experts theorizing how places like Disney World might be able to offer NFT entry and experiences,” Man says in a news release. “We’re not just talking about it, though — we’re doing it, and we are the first in the world, as far as I know.”

Each NFT pass is available for $170 to $210. Passes can be purchased with several types of cryptocurrency.

The Lago Mar lagoon’s NFT partner is OpenSea, an NFT marketplace. OpenSea’s investors include Dallas Mavericks owner and Shark Tank investor Mark Cuban, Austin entrepreneur and author Tim Ferriss, and NBA star and former University of Texas basketball standout Kevin Durant.

It's possible that NFT passes someday could pop up at Lagoon Development’s other waterparks. It already operates a crystal lagoon in Humble, is building another one in Iowa Colony, and expects to break ground soon on lagoons in Cypress, Katy, and Splendora.

To say that NFTs are exploding in popularity in the Houston area and elsewhere is a massive understatement. One study shows NFT sales hit $17.7 billion in 2021, up from $82.5 million in 2020, according to the Axios news website. Investment bank Jefferies predicts the value of the global NFT market will exceed $35 billion in 2022 and $80 billion in 2025, the CoinDesk news website reports.

The Texas City lagoon is just one of many businesses being captivated by the growing allure of NFTs. For instance, speculation continues to swirl that Disney’s theme parks will eventually adopt NFT season passes.

Furthermore, the NBA’s Dallas Mavericks may turn to NFTs for ticketing, and Southern California’s annual Coachella music festival is selling lifetime passes as NFTs.

“NFT tickets have the ability to not only take ticketing technology to the next level, but to also enable direct relationships between the seller and the buyer, and the performer and the fan — creating a connection that begins as soon as the NFT ticket is purchased, and continuing long after the event has ended,” the Better Marketing blog points out.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”