Khaliah Guillory, founder of Nap Bar, says she hopes to expand to 30 locations in three years. Photo courtesy Khaliah Guillory

Editor's note: These Houston innovators are making big strides in the fields of neurotechnology, neurodevelopmental diagnosis, and even improving the way we rest and recharge.

For our latest roundup of Innovators to Know, we meet a researcher who is working with teams in Houston and abroad to develop an innovative brain implant; a professor who has created an AI approach to diagnosis; and a local entrepreneur whose brand is poised for major expansion in the coming years.

Jacob Robinson, CEO of Motif Neurotech

Houston startup Motif Neurotech has been selected by the United Kingdom's Advanced Research + Invention Agency (ARIA) to participate in its inaugural Precision Neurotechnologies program. The program aims to develop advanced brain-interfacing technologies for cognitive and psychiatric conditions. Three Rice labs will collaborate with Motif Neurotech to develop Brain Mesh, which is a distributed network of minimally invasive implants that can stimulate neural circuits and stream neural data in real time. The project has been awarded approximately $5.9 million.

Motif Neurotech was spun out of the Rice lab of Jacob Robinson, a professor of electrical and computer engineering and bioengineering and CEO of Motif Neurotech.

Robinson will lead the system and network integration and encapsulation efforts for Mesh Points implants. According to Rice, these implants, about the size of a grain of rice, will track and modulate brain states and be embedded in the skull through relatively low-risk surgery. Learn more.

Dr. Ryan S. Dhindsa, Dhindsa Lab

Dr. Ryan S. Dhindsa, assistant professor of pathology and immunology at Baylor and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and his team have developed an artificial intelligence-based approach that will help doctors to identify genes tied to neurodevelopmental disorders. Their research was recently published the American Journal of Human Genetics.

Dhindsa Lab uses “human genomics, human stem cell models, and computational biology to advance precision medicine.” The diagnoses that stem from the new computational tool could include specific types of autism spectrum disorder, epilepsy and developmental delay, disorders that often don’t come with a genetic diagnosis.

“Although researchers have made major strides identifying different genes associated with neurodevelopmental disorders, many patients with these conditions still do not receive a genetic diagnosis, indicating that there are many more genes waiting to be discovered,” Dhindsa says. Learn more.

Khaliah Guillory, Founder of Nap Bar

From nap research to diversity and inclusion, this entrepreneur is making Houston workers more productiveFrom opening Nap Bar and consulting corporations on diversity and inclusion to serving the city as an LGBT adviser, Khaliah Guillory is focused on productivity. Courtesy of Khaliah Guillory

Khalia Guillory launched her white-glove, eco-friendly rest sanctuary business, Nap Bar, in Houston in 2019 to offer a unique rest experience with artificial intelligence integration for working professionals, entrepreneurs and travelers who needed a place to rest, recharge and rejuvenate.

Now she is ready to take it to the next level, with a pivot to VR and plans to expand to 30 locations in three years.

Guillory says she’s now looking to scale the business by partnering with like-minded investors with experience in the wellness space. She envisions locations at national and international airports, which she says offer ripe scenarios for patrons needing to recharge. Additionally, Guillory wants to build on her initial partnership with UT Health by going onsite to curate rest experiences for patients, caregivers, faculty, staff, nurses and doctors. Colleges also offer an opportunity for growth. Learn more.

Khaliah Guillory, founder of Nap Bar, says she hopes to expand to 30 locations in three years. Photo courtesy Khaliah Guillory

Houston startup Nap Bar pivots with VR and big plans for growth

power nap

Houston’s Khaliah Guillory takes a 30-minute nap every day. She says this is how she’s so productive.

The habit also led to the founding of her white-glove, eco-friendly rest sanctuary business, Nap Bar.

Guillory launched the luxury sleep suites company back in 2019 to offer a unique rest experience with artificial intelligence integration for working professionals, entrepreneurs and travelers who needed a place to rest, recharge and rejuvenate. The company was named a Houston Innovation Awards finalist last year.

She says naps are backed by science. And by her professional network, too.

“Once I polled and surveyed my friends, most of them said that they also took naps during their lunch break, whether it be in their office or in their car,” says Guillory, former vice president of marketing strategy at Wells Fargo. “Once they overwhelmingly agreed that they would absolutely use a dedicated place for them to take naps if I created it, I got to work, and Nap Bar was born.”

Simply put, Guillory has effectively made it acceptable and, yes, even cool for working adults to take naps.

“I played D1 basketball at the University of Central Florida and that’s really where I learned the art of a power nap and the benefits of it,” Guillory says. “And I just continued to nap throughout my corporate career. So, in November of 2018, I retired from corporate America … I just knew I had a higher calling to do something else.”

Guillory first opened up shop in Rice Village as a beta test for her novel nap idea and it took off. She soon forged strategic partnerships with organizations like UT Health, where Nap Bar provided much-needed naps to postpartum mothers.

“Nap Bar showed what the benefits of a good nap was, specifically to postpartum moms in terms of mental stressors, productivity, and things of that nature,” Guillory says.

In November 2019, Guillory moved Nap Bar to The Galleria and says the business produced revenue from day one. However, in March 2020, she was forced to shut us down due to the COVID-19 pandemic.

“I promised myself that I was not going back to corporate America, so I pivoted. I moved forward by creating a better sleep box, with a vegan pillow mist and soy-based candle. I also became a certified sleep coach. And I just kept pivoting from there, reinventing Nap Bar as a company,” she says.

One pivot included adding a virtual reality sleep experience, MetaSnooze.

“MetaSnooze is a really cool technology that offers sleep therapy and relaxation that I curated myself,” Guillory says. “Basically, the user puts on the VR headset, and it escapes them. They're transported to places all over the country. For example, they're sitting in serene environments all the while listening to these rhythmic beats that are designed to help them release and relax. Visualizations have been scientifically proven to improve one’s mental health and mental stressors.”

Guillory initially rolled out MetaSnooze in 2020 at events like South by Southwest and kept improving the experience and building her business. By February 2024, she was curating a wellness experience at The Grammy Awards.

“That was huge for us,” Guillory says. “Being able to get feedback from the celebrities, with a handful of them even inquiring where they could purchase the headset. They were excited about the future of Nap Bar, so that was really, really cool.”

The widespread interest in Nap Bar has Guillory thinking big. She aims to expand to 30 locations in three years.

“When I say that, it sounds ambitious,” says Guillory. “It is, but I come from the school of thought that if you shoot for 30 and you get 25, no one's going to shake their finger at you for doing that, right? It's really aiming towards this big, hairy, audacious goal. I learned that in corporate America. So, what we're looking to do now is raise money like crazy.”

Guillory says she’s now looking to scale the business by partnering with like-minded investors with experience in the wellness space.

She envisions locations at national and international airports, which she says offer ripe scenarios for patrons needing to recharge. Additionally, Guillory wants to build on her initial partnership with UT Health by going onsite to curate rest experiences for patients, caregivers, faculty, staff, nurses and doctors. Colleges also offer an opportunity for growth.

“We’ve done some really cool pop-ups with the University of Houston, where we brought the rest experience on campus,” Guillory says. “That means we bring a portable, full-size, organic mattress with disposable sheets, as well as our virtual reality experience.”

Nap Bar will also serve companies, office buildings, and even sports venues, according to Guillory.

“We can literally go any and everywhere,” she says. “Our collected data suggests that we’ve just got to go where sleepy people are so that they can get restorative sleep.”

From a pricing standpoint, Nap Bar’s model is a dollar a minute. Depending on where the client is, the pop-up experience is based on a day rate or a half-day rate, starting at $4,000.

Add-ons include a full-size organic mattress or hosting a masseuse or massage therapist onsite.

With the Grammys already under her belt, Guillory would like to see Nap Bar utilized at the 2028 Olympics and build partnerships with other virtual reality companies to bring its licensed MetaSnooze software to the masses.

She also sees opportunities in athletic treatment, sleep apnea, and insomnia.

“We have done several studies with proven results that MetaSnooze has reduced mental stressors and anxiety,” Guillory says. “I'm excited about what the future holds for MetaSnooze. It definitely is a game-changer … We will continue to innovate sleep or provide sleep resources and tools in a very innovative way.”

These three innovators are ones to look out for. Courtesy photos

3 Houston innovators to know this week

Who's who

From venture capital funding to nap research, these Houston innovators are leading the way in their industries. This week's innovators to know are a finance expert, LGBT leader and productivity expert, and a Houston expat making big moves in real estate.

Remington Tonar, managing director at The Cannon Houston

Courtesy of Remington Tonar

A banker, a crowdfunding specialist, and a venture capital expert walk into a room. It might be the beginning of a joke, or it might just be how Remington Tonar and a few other panelists contributed to Houston Community College's Small Business Summit.

The panel discussed different avenues for funding startups have. Tonar represented the venture capital firms — a type of funding that's currently. changing.

"There's a new phenomenon in venture where a lot of early stage investors and angel investors are looking at social impact investing," Tonar says. "They want to invest in women- or minority-owned businesses or companies that have a sustainability or social impact component to them. For those investors, the return demands are much more flexible." Read the full story here.

Khaliah Guillory, founder of Nap Bar

Courtesy of Khaliah Guillory

Khaliah Guillory needed a place to nap one day when commuting with her wife into the city from their home in Richmond, Texas. She usually resorted to a quick car nap to get her back to 100 percent, but it was weird to do that with someone else in the car. So, she created it, and Nap Bar was born.

Guillory, who also specializes in diversity and inclusion with her consulting company, KOG & Company, serves on the city's LGBT Advisory Board. She's the third installment of InnovationMap's Innovating Pride feature. Read the full interview here.

Jonathan Wasserstrum, founder and CEO of SquareFoot

Courtesy of SquareFoot

Houston native Jonathan Wasserstrum started a company and took it to New York City. He now has over 10 years of real estate experience and still runs that company — SquareFoot. But even he remembers the days of startup life that consisted of never knowing where your office might be in a year or even in a few months.

Wasserstrum wrote a guest article for InnovationMap about the things to consider before you take the leap and move to a coworking space. Click here to read the guest column.

From opening Nap Bar and consulting corporations on diversity and inclusion to serving the city as an LGBT adviser, Khaliah Guillory is focused on productivity. Courtesy of Khaliah Guillory

From nap research to diversity and inclusion, this entrepreneur is making Houston workers more productive

Featured Innovator

Khaliah Guillory is an avid napper — and she's had to be. A multiple hat wearer and big proponent of side hustles, she's always piled responsibilities high on her plate.

Earlier this year left a corporate leadership position to open Nap Bar in Rice Village, but for years before that, she had her diversity and inclusion side hustle, KOG & Company. She works with companies — big and small — to integrate the best diversity and inclusion initiatives into the workplace.

"The intersection between KOG and Nap Bar and the common denominator is productivity and performance," Guillory says. "From a corporate standpoint — even when you think about diversity and inclusion — it all boils down to we want people who don't look like us or don't come from where we come from to be productive and perform well."

Guillory, who is this week's Pride Month Featured Innovator on InnovationMap, also serves on Mayor Sylvester Turner's LGBT Advisory Board.

InnovationMap: When did you know you wanted to be an entrepreneur?

Khaliah Guillory: I was 8 or 9 years old, and my family drank a lot of soda. Where I grew up in Port Arthur, Texas, you could go and trade in cans for change. I would go outside, line up all the cans, and step on them to crush them. I saw an infomercial about a can crusher. It made my business more efficient. That's when my entrepreneurial journey started.

IM: How did The Nap Bar come about? 

KG: I have always been an avid napper. When I was in Kindergarten, and the teacher would say go grab your red or blue mat, I did it and I was out. I enjoyed naptime. In high school, I played basketball and I napped at the end of school. When I got into college, I played basketball at the University of Central Florida. My days would start at 5 am and wouldn't end until midnight. The only way I was able to graduate on time and maintain my grades for my scholarships was napping. It just continued throughout my professional career, and I started napping in my car.

One day, my wife and I commuted into the city — we live in the Sugar Land/Richmond area. We had about an hour and a half to spare. It was nap time, but it would be awkward with her in the car. She suggested Googling naps in Houston. She says, "We live in Houston, there's got to be a place where you could take a quick nap." There was no such place. She told me I should create it. That was April of last year.

IM: Then what did you do to get the ball rolling?

KG: The next day I surveyed all my friends and asked them if I was the only one out here napping. I quickly realized that I wasn't. Specifically, 52 percent of Americans, according to Amerisleep, admitted to napping at work. I committed to doing more research. I've committed 10,000 plus hours to researching the benefits to napping and the indicators of sleep exhaustion. Fast forward to November of last year, I transitioned away from my C-level position at a Fortune 500 company to really pursue Nap Bar.

IM: How’s business been?

KG: We just celebrated our 30th day of business a couple of weeks ago. We are already generating revenue. We are excited for what's to come. June is shaping up to be a real opportunity for us to be in the black, and July is shaping up to have a lot of events. We found that our biggest challenge is educating the masses on the benefits of taking a chill session in the middle of the day, and also educating on the indicators of what it's like to be sleep deprived.

IM: With KOG & Company, your other company, you’ve worked for years with large companies to help incorporate diversity and inclusion. How does that tie into your nap research?

KG: The intersection between KOG and Nap Bar and the common denominator is productivity and performance. From a corporate standpoint — even when you think about diversity and inclusion — it all boils down to we want people who don't look like us or don't come from where we come from to be productive and perform well. The best place for any corporation that has a philosophy or a vision of values and embraces corporate social responsibility is to acknowledge that people are going to be the heartbeat of their company.

IM: What do organizations — from startups to Fortune 500 companies — need to know about diversity and inclusion?

KG: The biggest thing is that from a culture standpoint, just simply hiring people to check a box isn't going to provide the desired ROI. It really, truly has to be embraced by the culture. If I am a business owner or corporation, and my goal is to have a diversity of talent, then I need to go where those people are. If I create and curate an environment with diversity and inclusivity, then going to recruit and then ask them what type of organization they want to work for and what it would look like — then go out and build that. And if they don't know where to start, they can hire me and I can hold their hand and give some real life experience. I've lived it as a banker, as a supervisor, and as a C-level executive.

IM: What’s surprised you about being on Mayor Sylvester Turner’s LGBT Advisory Board?

KG: I think what surprised me most about is that the city of Houston is really progressing and striving. It just makes sense. We're the most diverse city in the country, and I applaud Mayor Sylvester Turner for assembling the LGBT Advisory Board and for appointing me.

The city of Houston — and all the entities that fall under it from a government landscape — is desiring a journey to get more training and education. How do we educate on how to report a hate crime. How do we make sure that city employees are showing up to work and are 100 percent comfortable in their own skin. The biggest surprise I'd have to say is that the city has done an incredible job with the training. I walked away from the meeting learning things that I didn't even know about the LGBTQ community.

IM: What does Pride Month mean to you?

KG: Pride means to me being comfortable in my skin as I am, who I am. The month is a pleasant reminder to be "me" every day, all day. Pride month means my uniqueness is celebrated, not tolerated which should be the norm everyday; not just a month. Pride means being secure in the community — workplace, networking event, the gym, basically everywhere — and confidently say "my wife."

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Portions of this interview have been edited.

The Nap Bar offers "pay-by-snooze" rest. Photo by Dominique Monday

New Rice Village nap bar refreshes sleep-deprived Houstonians

Stay woke

Khaliah Guillory wants to put you to sleep. To clarify: She wants you to nap. And the power nap is all the rage right now. Busy workers, executives and entrepreneurs in New York, Europe, and Japan are all napping during the day — taking a short snooze that not only helps them be more productive in their daily tasks, but allows them to be healthier.

"Americans lose 1.2 million work days because of sleep deprivation," Guillory tells CultureMap. "That costs the economy $411 billion. And the Centers for Disease Control estimate that driving while you're sleep deprived is the equivalent of driving under the influence."

To counter the trends, Guillory will open Nap Bar in Rice Village. Slated for a late April unveiling, a pay-by-the-snooze napping facility will be at the back of New Living. Guillory has partnered with the company, already known for its commitment to sustainability. Nap Bar's custom-patented napping pods are designed with sound-proof materials and contain organic, nontoxic Bungaloom mattresses and bedding.

A Comfort Concierge will greet visitors and lead them to a private suite surrounded with T.L.C. There are also two shared nap pods with twin mattresses available. Naps are scheduled 20 to 26 minutes for short-term alertness, or longer, if needed. A 20-minute snooze will set you back $25, while 26 minutes run $32. (If you're looking for a full hour, that's available for $69). Sleeping pods have blackout curtains and are soundproof.

Guillory has also made the napping experience into a luxury one so Nap Bar nappers receive complimentary aromatherapy and custom brain wave therapy with every siesta. Other add-ons include, lymphatic massages, hot showers, espressos, and EarthCraft Juicery blends that are crafted from raw, healing ingredients. The all-organic experience all designed to provide gentle healing and peaceful rest.

"Our culture tells us that if you're napping during the day, you're either a kid or you're lazy," says Guillory. "But that's not true. If you take as little as 20 minutes to nap, you'll feel revitalized."

A snooze story
Guillory didn't intend to become a nap guru. Like many things in life, however, necessity became the mother of invention. While working as an executive for a Fortune 500 company, Guillory was traveling heavily, catching brief bits of shut-eye in airport lounges or her car. At one point she found herself in Richmond, with an hour and a half to kill before her next meeting in Houston. Driving straight into town would make her far too early for her appointment. There wasn't time to go home. And checking into a hotel seemed silly.

"That's when my wife said to me, Google nap spaces in Houston," she recalls. She did. There were none. And that's why she created her own. "I wanted a safe haven for people to unplug," Guillory says. "It doesn't have to be full-on sleep. It can be relaxation, meditation, whatever you need."

And far from resting on her own laurels with her business on the cusp of opening, Guillory is pursuing other nap-centric opportunities. She's looking to partner with area businesses to incorporate nap pods into their space for employees, and is planning a Nap Bar Snooze Unit, a mobile tour bus that will "roll through downtown and let people take power naps," she explains.

She generated a great deal of interest when she took her concept on the road to Bush Intercontinental Airport earlier this week, displaying the nap pod and sharing the feedback she'd received from Nap Bar's beta testers. That input is something she takes seriously; when Nap Bar debuts, it'll be with products that her testers recommended — and they had opinions on everything from the bedding to the materials used in the pod.

"I want to turn sustainable rest into sustained productivity," says Guillory. "And I think this is just what Houston needs."

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This article originally ran on CultureMap.

Oils and scents help you relax. Photo by Dominique Monday

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Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.