Meet the female health tech founders being accelerated by Ignite Healthcare this year. Photo courtesy of Ignite

Last month, a Houston organization dedicated to supporting female founders in health care kicked off its 2023 accelerator with cohort participants from across the country.

Ignite Healthcare Network, based in Houston, is a nonprofit founded on the mission of supporting women in health care. Ignite established its 12-week accelerator program to help advance and connect female health tech founders with mentors and potential clients as their startups scale.

"We have 19 founders doing great work, and we have them matched with three to four advisors helping to mentor them," Ayse McCracken, founder and board chair of Ignite tells InnovationMap. "We also have a virtual learning program, which is new this year, and we have two sessions of those a week."

The programming is curated to tackle the health tech industry's biggest topics and provide advice for a small group of engaged startups, McCracken explains. In its fifth year now, the program has a large group of partners that are involved.

"We've had 91 companies come through our program in the last fours years," McCracken says. "They've raised over $550 million."

The cohort concludes on November 9 with the Fire Pitch Competition at the Ion, where a handful of finalists — selected by Ignite's team of mentors — will present to win the top award.

This year's cohort includes:

  • Somer Baburek, CEO and co-founder of Hera Biotech
  • Sue Carr, president and founder of CarrTech Corp
  • Suchismita Acharya, CEO, chief strategy officer, and co-founder of AyuVis
  • Asma Mirza, CEO and founder of Steradian Technologies
  • J’Vanay Santos, CEO and founder of MyLÚA Health
  • Maureen Brown, CEO and co-founder of Mosie Baby
  • Elizabeth Friedman, president and founder of Safen Medical Products
  • Meghan Doyle, CEO and co-founder of Partum Health
  • Marina Tarasova, COO and co-founder of Paloma Health
  • Melissa Bowley, CEO and founder of Flourish Care
  • Molly Hegarty, CEO and founder of Junum
  • Patty Lee, CEO and co-founder of Orbit Health
  • Piyush Modak, Vice President of R&D and co-founder of EndoMedix
  • Debbie Chen, CEO and founder of Hydrostasis
  • Rachael Grimaldi, CEO and co-founder of CardMedic
  • Rachna Dhamija, CEO of Ejenta
  • Carolyn Treviño Jenkins, CEO and co-founder of We Are Here
  • Lyn Markey, CEO and co-founder of XTremedy
  • Camille O’Malley, CTO and co-founder of XTremedy
Last year, Joanna Nathan, CEO of Houston-based Prana Thoracic, won the top award for her company.
Seventeen of the RBPC student teams walked away with investment prizes this year. Photo courtesy of Rice

Houston student startup competition doles out record-breaking more than $3M in prizes

show me the money

Over the weekend, Houston hosted what is known as the world’s largest and richest intercollegiate student startup competition, and a Texas team took the overall win and over $3 million in investment prizes were given out at the annual banquet.

The 2023 Rice Business Plan Competition was held May 11-13 and included mentoring, pitching, and networking for the 42 student teams with over 350 judges before culminating in over 80 prizes being announced. The $3.4 million in investment and in-kind prizes marks the largest yet for the 23-year-old competition.

"Judges told us that the quality of the startups at this year’s competition was the best ever,” says Catherine Santamaria, director of the RBPC, in the news release. “One judge went so far as to say that every startup this year was worthy of investment.”

Over 450 startups applied to the competition, and the 42 startups selected hailed from 35 universities from five countries. There were five categories: energy, clean tech and sustainability; life sciences and health care solutions; consumer products and services; hard tech; and digital enterprise. Based on the judges scores, seven startups reached the finals, and this year, three Texas teams made the finals, with two being from Rice University.

All 42 companies were eligible for investment or in-kind prizes, and, even though $1.75 million in prizes was expected to be awarded, some of this year's investors doubled — or even tripled — down on investment awards. While the finalists walked away with various in-kind prizes too, here's a round up of the investment prizes each startup won at the awards.

Zaymo, Brigham Young University — $885,000

Zaymo, a tool for e-commerce brands that embeds the shopping experience within customers’ email, won the most amount of money at the awards ceremony. The company won third place and a $50,000 Investment Prize sponsored by David Anderson, Jon Finger, Anderson Family Fund, Finger Interests, Greg Novak and Tracy Druce. Zaymo also won the following awards:

  • $200,000 OWL Investment Prize
  • $100,000 Houston Angel Network Investment Prize
  • $500,000 Softeq Venture Fund Prize
  • $15,000 Eagle Investors Prize
  • $20,000 Novak Druce Carroll Investment Prize

Boston Quantum, Massachusetts Institute of Technology — $455,000

Boston Quantum, which is using enterprise quantum computing software to disrupt the financial industry, won the second-most amount of investment prizes and sixth place in the competition.

  • $5,000 Chevron Technology Ventures Sixth-Place Cash Prize
  • $300,000 OWL Investment Prize
  • $125,000 Softeq Venture Fund Prize
  • $25,000 Urban Capital Network Diversity Investment Prize in partnership with South Loop Ventures

FluxWorks, Texas A&M University — $350,000

Based on the judges scores, the big winner was FluxWorks, a Texas company that's technology includes magnetic gears that are four times quieter than standard with 99 percent efficiency and can offer unprecedented reliability from outer space to under the sea and even inside the human body. The company won the $350,000 GOOSE Capital Investment Grand Prize.

Skali, Northwestern University — $300,000

Skali, which didn't make it into the prestigious finalist positions, still walked away with $300,000 courtesy of the Softeq Venture Fund Prize. Skali's technology aims to better equip flights with medical emergency assistance.

TierraClimate, Rice University — $280,000

TierraClimate, a marketplace for selling verified carbon offsets to corporate buyers, won fourth place and the Norton Rose Fulbright $5,000 Prize. The company also won a $200,000 Softeq Venture Fund Prize and the $75,000 OWL Investment Prize.

AirSeal, Washington University in St. Louis — $250,000

Another non-finalist that still scored big was AirSeal, a company that's created a simple blood test for cardiovascular diagnostics. The startup secured the $250,000 TMC Innovation Healthcare Investment Prize.

Sygne Solutions, Rice University — $200,000

Sygne Solutions, a startup on a mission of eliminating a group of chemicals known as PFAS in water through its patent-pending technology, won second place and the $100,000 Investment Prize, sponsored by David Anderson, Jon Finger, Anderson Family Fund, Finger Interests, Greg Novak and Tracy Druce. The company also received the $100,000 TiE Houston Angels Investment Prize.

BlueVerse, Texas Tech University — $145,000

BlueVerse, a startup with tech to merge social media with reviews and rewards for small businesses, didn't make the finals but walked away with on of the $125,000 Softeq Venture Fund Prizes and the $20,000 Novak Druce Carroll Investment Prize.

Atma Leather, Yale University —$130,000

Atma Leather, a material innovation company that's created plant-based leather from banana stems and other crop waste, came in fifth place and secured the $5,000 EY Fifth-Place Cash Prize. The startup also won:

  • $75,000 OWL Investment Prizes
  • $50,000 nCourage Investment Group’s Courageous Women Entrepreneurs Investment Prize

MyLÚA Health, Cornell University — $30,000

MyLÚA Health's AI technology supports the maternal health industry. The company won the $30,000 Pearland Economic Development Corporation Spirit of Entrepreneurship Prize.

Active Surfaces, Massachusetts Institute of Technology — $25,000

With its flexible and lightweight solar panel technology, Active Surfaces scored the $25,000 New Climate Ventures Sustainability Investment Prize.

Integrated Molecular Innovations, Michigan Technological University — $25,000

Integrated Molecular Innovations, which created a wearable device that can monitor hormone levels, won the $25,000 Southwest National Pediatric Device Consortium Prize.

MiraHeart, Johns Hopkins University — $25,000

MiraHeart, which created a non-invasive way of monitoring child heart conditions, also won the $25,000 Southwest National Pediatric Device Consortium Prize.

Biome Future, University of Florida — $20,000

Biome Future, which creates ocean-safe chemicals via microbes in corals, won one of the $20,000 Novak Druce Carroll Investment Prizes.

Citrimer, University of Michigan — $10,000

A sustainable materials company, Citrimer won the $10,000 NABACO RBPC Alumni Network Prize.

Thryft Ship, University of Georgia — $10,000

Thryft Ship, which streamlines the shipping process for social media sellers, won a $10,000 nCourage Investment Group’s Courageous Women Entrepreneurs Investment Prize.

Pathways, Harvard University  — $5,000

Pathways, which is developing a full-stack sustainability platform for the construction industry, won $5,000 Shell Ventures Seventh-Place Cash Prize.

In addition to these investment prizes, the startups have the chance to score in-kind prizes. This year, that included:

  • $6,667 Baker Botts Legal Services In-Kind Prize to FluxWorks, Texas A&M University
  • $6,667 Baker Botts Legal Services In-Kind Prize to Sygne Solutions, Rice University
  • $6,667 Baker Botts Legal Services In-Kind PrizeFluxWorks to Zaymo, Brigham Young University
  • $10,000 New York Technology Capital CFO Consulting In-Kind to FluxWorks, Texas A&M University
  • EFN Mentoring Services to all startup competitors
  • Amazon Web Services to all startup competitors
  • Stage 2 Competition Entry to Sygne Solutions, Rice University
All 42 of the RBPC companies wins at least $950. In each of the three semi-final rounds, third place wins $2,000, fourth place wins $1,750, and fifth place wins $1,500. The wild card round, which acts as a second-chance competition for the companies that didn't originally make it to the finals, advances the wild card winner into the finals and also awards second place $1,000, third place $975, fourth place $950, and fifth place $950.
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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.

Elon Musk's SpaceX is about to make its debut on Wall Street

Money Moves

Elon Musk's rocket company SpaceX will make its debut on Wall Street Friday, June 12, and both institutional and retail investors are expected to gobble up the 555.6 million shares going up for sale at $135 apiece. Musk, already the world's richest man, could become its first trillionaire.

SpaceX is likely to become the biggest IPO ever, with proceeds of around $75 billion. SpaceX hopes to become the first company to send people to Mars. In fact, part of Musk’s future compensation depends on SpaceX eventually establishing a colony of at least 1 million people on the red planet.

Why SpaceX is going public now

In a video conference on Musk's social media platform X, he told JPMorgan CEO Jamie Dimon that people have suggested for the last 10 years that he take SpaceX public. He's doing it now because the company plans to put 100,000 next-generation Starlink satellites into orbit. Deploying AI data centers in space is a “massive new growth base and you need capital for that,” he said.

Going public provides access to the capital that SpaceX needs. But it also exposes it to more scrutiny from shareholders and more regulatory oversight. That includes filing quarterly financial reports, which critics say incentivizes short-term thinking over longer-term planning and creates unnecessary costs for a company. Securities regulators are currently soliciting public comment on a proposal to require public companies to file the financial reports only twice every year.

How the IPO impacts the company

Musk will hold the majority of a special class of shares, giving him control over decisions related to company strategy, finances and personnel. On the latter, because of his ownership of most of these Class B shares, the only person who can fire Musk as CEO is Musk.

The company credits Musk with being the “driving force” behind its growth, innovation and success. But what happens if Musk is no longer in the picture? SpaceX warns that the loss of Musk could disrupt its ability to execute its strategy as well as hurt its “reputation and relationships with customers, partners and other stakeholders.”

The company also warns that finding a replacement with the same skills and experience as Musk would be time-consuming, if not nearly impossible. As Wedbush Securities analyst Dan Ives wrote Wednesday, “At the end of the day Musk is SpaceX and SpaceX is Musk.”

What could make or break SpaceX

Currently in the test phase, the gigantic reusable Starship rocket is key to SpaceX realizing Musk's ambitions. Much of the commercial space business hinges on SpaceX developing Starship’s capability to be fully reusable and hearty enough for a quick turnaround between flights. If that doesn't happen, SpaceX warns that putting data centers and satellites in space will take longer and cost more money, meaning it risks customers bailing on the company.

Analysts say that by pioneering reusable rockets, SpaceX has established a clear lead on competitors such as Blue Origin, led by Amazon founder Jeff Bezos. The Starlink satellite business competes with, among others, AST SpaceMobile – which is relying on a SpaceX rocket to send its latest generation of satellites into orbit next week.

The prospectus filed last week says SpaceX’s biggest potential market is the sale of business-oriented artificial intelligence products designed to transform how people get work done. It’s an opportunity SpaceX predicts would be worth $22.7 trillion if it could somehow dominate rivals like Anthropic, OpenAI and Microsoft in a highly competitive industry. But the prospectus shows no clear path to profitability for the xAI business, which merged with SpaceX earlier this year.

Why Wall Street is paying attention

If the SpaceX IPO is as successful, the stock could quickly join the Nasdaq 100, a widely followed index that tracks the 100 largest non-financial companies in the composite. That's important because some popular funds, such as the $460 billion QQQ exchange-traded fund, mimic the index and will automatically buy whatever is listed in the index.

Nasdaq recently changed its rules to allow select companies to enter the Nasdaq 100 after just 15 trading days.

S&P Dow Jones Indices, on the other hand, is sticking to established and more traditional thresholds that will not allow SpaceX or other companies with gargantuan IPOs faster entry into its S&P 500 index. That means even high-profile companies will still need to wait for their stocks to trade a full 12 months before they can enter the index.

Companies want to be in the S&P 500 in particular because it's arguably the most important index on Wall Street, with trillions of dollars either mimicking it exactly or benchmarked against it. Vanguard's VOO fund that tracks the S&P 500 has roughly $950 billion invested in it, for example.