Memorial Park Conservancy's renovations include some projects that are rare or never been done before. Photo courtesy of MPC

Memorial Park is undergoing a huge transformation that is mixing a little bit of old with the new.

The Memorial Park Master Plan includes adding breathtaking new projects — like water features, a new athletic complex, and more — as well as conservation efforts that restore parts of the land that were native coastal prairie. The project is a collaborative effort between Memorial Park Conservancy, Uptown Houston TIRZ, and Houston Parks and Recreation Department to redevelop the 1,500-acre park.

The Master Plan is set to deliver a series of projects ahead of 2028, and there are a few initiatives that are innovative and different from other urban parks' transformations, notes MPC's president and CEO Shellye Arnold.

The Land Bridge

Photo courtesy of MPC

A big part of Memorial Park's transformation is restoring the park to native species and ecosystems.

"We're taking ball fields, parking lots, and roads and converting them back to what was here — native wetland coastal prairie," Arnold says. "This serves important stormwater purposes."

In order to connect two native coastal prairie lands on either side of Memorial Drive, MPC is building a unique 30-foot-high land bridge the size of three-and-a-half football fields. The space will be large enough that you don't even realize you're standing over a busy street, Arnold says.

The prairies will serve an important purpose for rainwater collection — a growing need within the city of Houston.

"We're channeling [rainwater] into this prairie where some of it can be absorbed, cleansed, slowed down," says Arnold. "And then what doesn't get slowed down and absorbed can flow through the prairie [on the other side], which is even bigger."

The Land Bridge also serves another purpose that park goers have wanted, Arnold says: Connectivity.

"[They] want access across the Memorial Drive — [they] want to safe access, and so this is the response. It's a pretty bold and visionary response," Arnold says.

BioCycling

Photo courtesy of MPC

In 2011, a major drought decimated the park and areas saw losses of 50 to even 90 percent of the canopy of trees. MPC and its team saved what could be saved, and the rest is serving a new purpose to the park.

"We took the trees that we lost on the drought that people felt such a tremendous loss for and ground them all up, and they are in a biocycle in a two-acre area in the back of the park," Arnold says.

The soil created — some of which includes manure from the animals at the Houston Zoo — has already been used on some plants in the park, and Arnold says those plants are thriving.

"It's cool that those those trees are giving life to the park," Arnold says.

Invasive species of trees that are plucked from out of the park are also being ground up and used in the same way.

"There isn't anything this big like this in an urban park setting like this kind of recycling effort," she says.

The biocycling process is scalable too.

"We could open this up to other organizations," Arnold says. "It's so much better ecologically to take trees and grind them up and use it inside the space rather than haul them out to landfill way outside of town and dump them."

The benefit to the program is that MPC can retain some of the soil it produces for these other organizations and use it on site.

Biodiversity initiatives and research

Photo courtesy of MPC

When putting the plans in place, MPC and its partners called on 25 of the best ecologists, as well as 50 more park and other types of consultants specializing in everything from insects and wildlife to prairies and trees.

Just as the Land Bridge is creating new prairie space, other initiatives throughout the park will be focused on eliminating invasive species and bringing back the natural ecosystem of the park.

The Easter Glades project, which is set to deliver next year, will have a habitat for fish, and will not allow any fishing or boating. Carolyn White, conservation director at MPC, is working with the Texas Wildlife Association to bring in the right species of fish.

Arnold says that MPC works with other organizations in an innovative way to bring native plants into MPC, since the park has the space for these organizations to use to cultivate and propagate plants.

"They bring their native plants and they grow them with their volunteers, and they leave us a little bit here," Arnold says. "We could never buy enough native plants to go inside this park."

Memorial Park Conservancy is gearing up to unveil one if its first projects within its 10-year master plan redevelopment. Photo courtesy of MPC

Memorial Park Conservancy plans to deliver its first project of its master plan redevelopment next year

Coming soon

Memorial Park Conservancy has until 2028 to deliver on its master plan redevelopment project, but if MPC president and CEO Shellye Arnold has anything to say about it, the plan will be completed way ahead of that.

The project is a collaborative effort between MPC, Uptown Houston TIRZ, and Houston Parks and Recreation Department to redevelop the 1,500-acre park. In 2011, a major drought decimated the park and areas saw losses of 50 to even 90 percent of the canopy of trees.

"As tragic as it was, it made people take action," says Arnold.

Following the drought, these organizations looked to the people to see what was needed and wanted by the 3 million visitors and residents of the 170 ZIP codes that frequent the park annually.

"There was a huge outcry to do something," Arnold says. "That something became an effort to define the future of the park in a way that would be powerful, bold, thoughtful, innovative, and very resilient. It would consider Houstonians of the future and Houstonians today. It would consider soils, storm water treatment, the wildlife, and what people want."

When putting the plans in place, MPC and its partners called on 25 of the best ecologists, as well as 50 more park and other types of consultants specializing in everything from insects and wildlife to prairies and trees.

The overall funding plan is a total of $205 million — MPC itself has a capital campaign goal of $50 million — with $32 million to go. A $70 million donation from the Kinder Foundation is the most significant contribution within the fundraising efforts. The foundation approached MPC asking to help contribute to the most transformative project in the master plan, Arnold says, and so they suggested the Eastern Glades, a park within a park and the first project within the master plan to deliver.

MPC expects the Eastern Glades to open next summer — and much of the construction has already been completed. The area will be a 100-acre park within a park with wetlands, a man-made pond, 9 acres of picnic space, and three picnic pavilions.

Eastern Glades

Photo courtesy of MPC

"The full 100-acre Eastern Glades project will provide an amenity that we do not have right now," says Arnold in a release, "a place to put down a blanket and read a book, relax on a park bench, or go for a leisurely walk and just enjoy being outdoors."

In addition to the Eastern Glades, the park will also reopen some relocated ballparks next year.

After next year, the MPC and its master plan partners will deliver a slew of other projects on a rolling basis.

Here are some other exciting ones you can expect in the next few years:

Running Complex

Photo courtesy of MPC

Running is such an important part of Memorial Park, Arnold says, citing the Seymour Lieberman's millions of annual visitors. The $19 million running complex is expected to deliver in 2022.

Memorial Groves

Photo courtesy of MPC

There's a section of Memorial Park that has more history than the rest of the land. The master plan includes a 100-acre, $21.5 million memorial for the fallen soldiers from Camp Logan that's expected to deliver in 2022.

"There were a handful of WWI training camps — this was one of the sites that was chosen," Arnold says. "We have archeological features in the park."

The memorial will feature native pine trees that will be planted in a formation that looks as if they are standing in attention.

The Land Bridge

Photo courtesy of MPC

Possibly the most striking of all the plans is the Land Bridge. The project will connect each of the prairie wetlands on either side of Memorial Drive with a 30-foot-high arch of land. The space will be large enough that you don't even realize you're standing over a busy street, Arnold says. The Land Bridge is planned to deliver in 2022.

Stormwater management

Photo courtesy of Mir

An ongoing part of the transformation will be stormwater management upgrades. MPC has budgeted $3 million to this asset of the renovation. While a part of the plan is tributaries for run-off water, bringing back prairie and wetlands will do a great deal to help abate stormwater.

"We're taking ball fields, parking lots, and roads and converting them back to what was here — native wetland coastal prairie," Arnold says. "This serves important stormwater purposes."

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”